Strain Name:
C57BL/6J-MtgxR8096Btlr/Mmmh
Stock Number:
067528-MU
Citation ID:
RRID:MMRRC_067528-MU
Other Names:
R8096 (G1)
Major Collection:

Strain Information

Cdk17
Name: cyclin dependent kinase 17
Synonyms: 6430598J10Rik, Pctk2
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 237459
VEGA: 10
HGNC: HGNC:8750
Homologene: 55666
Actn4
Name: actinin alpha 4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 60595
HGNC: HGNC:166
Homologene: 55857
Arid5b
Name: AT-rich interaction domain 5B
Synonyms: Mrf2, 5430435G07Rik, Mrf2alpha, Mrf2beta, Desrt
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 71371
VEGA: 10
Homologene: 45872
Scrib
Name: scribbled planar cell polarity
Synonyms: Scrb1, Crc
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 105782
Homologene: 44228
Zfp280d
Name: zinc finger protein 280D
Synonyms: Suhw4
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235469
Homologene: 17151
Trim24
Name: tripartite motif-containing 24
Synonyms: Tif1a, D430004I05Rik, A130082H20Rik, TIF1alpha
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 21848
Homologene: 20830
Acin1
Name: apoptotic chromatin condensation inducer 1
Synonyms: Acinus, 2610510L13Rik, 2610036I19Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 56215
Homologene: 22853
Pigr
Name: polymeric immunoglobulin receptor
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 18703
HGNC: HGNC:8968
Homologene: 1984
Slc39a8
Name: solute carrier family 39 (metal ion transporter), member 8
Synonyms: BIGM103, 4933419D20Rik, ZIP8
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 67547
Homologene: 11155
Cacna2d3
Name: calcium channel, voltage-dependent, alpha2/delta subunit 3
Synonyms: alpha 2 delta-3, alpha2delta3
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 12294
Homologene: 74929
Cux2
Name: cut-like homeobox 2
Synonyms: Cutl2, ENSMUSG00000072641, Cux2, Cux-2, 1700051K22Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 13048
Homologene: 22426
Tex30
Name: testis expressed 30
Synonyms: 3110030D08Rik, 1700029F09Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 75623
Homologene: 16344
Zfp958
Name: zinc finger protein 958
Synonyms: BC003267
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 233987
Homologene: 129582
Ryr1
Name: ryanodine receptor 1, skeletal muscle
Synonyms: calcium release channel isoform 1, Ryr, skrr
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 20190
Homologene: 68069
Tnik
Name: TRAF2 and NCK interacting kinase
Synonyms: 4831440I19Rik, 1500031A17Rik, C530008O15Rik, C630040K21Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 665113
Homologene: 77943
Pclo
Name: piccolo (presynaptic cytomatrix protein)
Synonyms: Pico, Acz
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 26875
Homologene: 69111
Muc4
Name: mucin 4
Synonyms: 4933405I11Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 140474
HGNC: HGNC:7514
Homologene: 124469
Srrm3
Name: serine/arginine repetitive matrix 3
Synonyms: 2900083I11Rik, SRm300-like, Srrm2l
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 58212
Homologene: 136723
Scn2a
Name: sodium channel, voltage-gated, type II, alpha
Synonyms: Nav1.2, A230052E19Rik, Scn2a1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 110876
Homologene: 75001
Tnn
Name: tenascin N
Synonyms: tenascin-W, Tnw
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 329278
Homologene: 18634
Astn1
Name: astrotactin 1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 11899
HGNC: HGNC:773
Homologene: 7233
Vrtn
Name: vertebrae development associated
Synonyms: 7420416P09Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 432677
VEGA: 12
Homologene: 41236
Muc5b
Name: mucin 5, subtype B, tracheobronchial
Synonyms: MUC9, MUC5, 2300002I04Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 74180
HGNC: HGNC:7516
Homologene: 136756
Igsf10
Name: immunoglobulin superfamily, member 10
Synonyms: CMF608, Adlican2, 6530405F15Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 242050
Homologene: 18712
Adgre4
Name: adhesion G protein-coupled receptor E4
Synonyms: Emr4, EGF-TM7, D17Ertd479e, Gpr127, FIRE
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 52614
VEGA: 17
Homologene: 64640
Grik1
Name: glutamate receptor, ionotropic, kainate 1
Synonyms: Glurbeta1, A830007B11Rik, GluK5, Glur5, D16Ium24, Glur-5, D16Ium24e
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 14805
HGNC: HGNC:4579
Homologene: 68992
Gpr87
Name: G protein-coupled receptor 87
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 84111
HGNC: HGNC:4538
Homologene: 13021
Or8u9
Name: olfactory receptor family 8 subfamily U member 9
Synonyms: MOR185-4, Olfr1044, GA_x6K02T2Q125-47640742-47639798
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 259013
Homologene: 100542
Mrc2
Name: mannose receptor, C type 2
Synonyms: Endo180, novel lectin, uPARAP
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17534
Homologene: 4408
Clca3a1
Name: chloride channel accessory 3A1
Synonyms: Clca1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 12722
HGNC: HGNC:2017
Homologene: 77224
Sphkap
Name: SPHK1 interactor, AKAP domain containing
Synonyms: A930009L15Rik, 4930544G21Rik, SKIP
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 77629
Homologene: 18172
Ggcx
Name: gamma-glutamyl carboxylase
Synonyms: vitamin K-dependent carboxylase
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 56316
HGNC: HGNC:4247
Homologene: 639
Tpra1
Name: transmembrane protein, adipocyte asscociated 1
Synonyms: Tpra40, 40kDa, Gpr175
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 24100
Homologene: 40799
Stx19
Name: syntaxin 19
Synonyms: A030009B12Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 68159
Homologene: 55777
Or10a3
Name: olfactory receptor family 10 subfamily A member 3
Synonyms: GA_x6K02T2PBJ9-11211854-11210853, MOR268-5, Olfr518
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258303
HGNC: HGNC:8162
Homologene: 133601
Or1l4
Name: olfactory receptor family 1 subfamily L member 4
Synonyms: MOR138-1, GA_x6K02T2NLDC-33885305-33886243, Olfr365
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258656
Homologene: 74156
Dynlrb2
Name: dynein light chain roadblock-type 2
Synonyms: DNLC2B, 1700009A04Rik, Dncl2b
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 75465
Homologene: 12601
Rsph14
Name: radial spoke head homolog 14 (Chlamydomonas)
Synonyms: 4933431K05Rik, Rtdr1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 71236
Homologene: 49382
Gm15922
Name: predicted gene 15922
Type: Gene
Species: Mouse
Chromosome: 7
Tnfsf13
Name: tumor necrosis factor (ligand) superfamily, member 13
Synonyms: TALL2, APRIL, 2310026N09Rik, TRDL1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 69583
Homologene: 56971
Trim68
Name: tripartite motif-containing 68
Synonyms: SS-56, F730114J12Rik, Rnf137
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 101700
Homologene: 9991
Scgb2b24
Name: secretoglobin, family 2B, member 24
Synonyms: C2b, Scgb2b3, Abpz, Abpbg24
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233090
Homologene: 83171
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 44,088,503 bp
  • A to T, chromosome 1 at 83,277,558 bp
  • A to G, chromosome 1 at 130,846,510 bp
  • A to G, chromosome 1 at 158,609,320 bp
  • C to T, chromosome 1 at 160,122,841 bp
  • T to A, chromosome 2 at 37,202,066 bp
  • T to A, chromosome 2 at 65,764,022 bp
  • T to A, chromosome 2 at 86,171,712 bp
  • G to A, chromosome 3 at 28,661,778 bp
  • A to T, chromosome 3 at 59,179,808 bp
  • G to T, chromosome 3 at 59,328,959 bp
  • T to C, chromosome 3 at 135,884,656 bp
  • T to A, chromosome 3 at 144,749,685 bp
  • A to G, chromosome 5 at 14,712,961 bp
  • A to G, chromosome 5 at 121,869,097 bp
  • T to A, chromosome 5 at 135,869,240 bp
  • G to T, chromosome 6 at 37,958,657 bp
  • G to A, chromosome 6 at 72,429,993 bp
  • C to T, chromosome 6 at 88,911,717 bp
  • C to G, chromosome 7 at 3,737,320 bp
  • A to G, chromosome 7 at 28,894,583 bp
  • C to A, chromosome 7 at 28,901,913 bp
  • A to G, chromosome 7 at 29,009,201 bp
  • T to A, chromosome 7 at 33,739,221 bp
  • A to G, chromosome 7 at 102,678,442 bp
  • A to T, chromosome 7 at 108,881,041 bp
  • T to C, chromosome 7 at 141,849,555 bp
  • G to T, chromosome 8 at 4,613,273 bp
  • A to G, chromosome 8 at 116,507,517 bp
  • T to C, chromosome 9 at 72,319,278 bp
  • T to A, chromosome 10 at 68,186,152 bp
  • T to A, chromosome 10 at 74,959,661 bp
  • T to G, chromosome 10 at 93,216,367 bp
  • A to G, chromosome 11 at 69,685,157 bp
  • G to T, chromosome 11 at 105,343,507 bp
  • C to T, chromosome 12 at 84,650,035 bp
  • A to G, chromosome 14 at 29,103,700 bp
  • G to A, chromosome 14 at 54,645,269 bp
  • A to T, chromosome 15 at 76,062,709 bp
  • T to A, chromosome 16 at 32,755,390 bp
  • A to C, chromosome 16 at 62,822,161 bp
  • C to T, chromosome 16 at 88,006,467 bp
  • T to A, chromosome 17 at 55,820,700 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R8096 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
067528-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.