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Strain Name:
C57BL/6J-MtgxR8329Btlr/Mmmh
Stock Number:
067859-MU
Citation ID:
RRID:MMRRC_067859-MU
Other Names:
R8329 (G1)
Major Collection:

Strain Information

Atg7
Name: autophagy related 7
Synonyms: 1810013K23Rik, Apg7l
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 74244
Homologene: 4662
Foxa3
Name: forkhead box A3
Synonyms: Tcf-3g, Hnf3g, Hnf-3g, Tcf3g
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 15377
HGNC: HGNC:5023
Homologene: 3308
Dop1b
Name: DOP1 leucine zipper like protein B
Synonyms: 0610038M01Rik, 2610510B01Rik, Dopey2
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 70028
VEGA: 16
HGNC: HGNC:1291
Homologene: 21068
Xpnpep1
Name: X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
Synonyms: D230045I08Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 170750
Homologene: 6424
Tnpo3
Name: transportin 3
Synonyms: 5730544L10Rik, C430013M08Rik, D6Ertd313e
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 320938
Homologene: 40848
Pik3c2a
Name: phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha
Synonyms: PI3KC2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18704
HGNC: HGNC:8971
Homologene: 20581
Gcn1
Name: GCN1 activator of EIF2AK4
Synonyms: GCN1L, G431004K08Rik, Gcn1l1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231659
HGNC: HGNC:4199
Homologene: 5887
Sbno2
Name: strawberry notch 2
Synonyms: Stno
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216161
VEGA: 10
Homologene: 8981
Cog3
Name: component of oligomeric golgi complex 3
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 338337
VEGA: 14
Homologene: 5854
Clptm1l
Name: CLPTM1-like
Synonyms: C130052I12Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218335
VEGA: 13
Homologene: 12767
Ralgps2
Name: Ral GEF with PH domain and SH3 binding motif 2
Synonyms: 1810020P17Rik, 9130014M22Rik, 4921528G01Rik, 2210408F11Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 78255
Homologene: 23421
Myo1d
Name: myosin ID
Synonyms: 9930104H07Rik, D11Ertd9e
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 338367
HGNC: HGNC:7598
Homologene: 45576
Oprl1
Name: opioid receptor-like 1
Synonyms: MOR-C, ORL1, XOR1, LC132, nociceptin/ orphaninFQ receptor, morc, N/OFQ receptor, NOP
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 18389
HGNC: HGNC:8155
Homologene: 22609
Aco1
Name: aconitase 1
Synonyms: Irp1, Irebp, Aco-1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 11428
HGNC: HGNC:117
Homologene: 1657
Apob
Name: apolipoprotein B
Synonyms: apob-100, apob-48
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238055
HGNC: HGNC:603
Homologene: 328
Ccdc3
Name: coiled-coil domain containing 3
Synonyms: 2310045O21Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 74186
Homologene: 12870
Tsg101
Name: tumor susceptibility gene 101
Synonyms: CC2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 22088
Homologene: 4584
Tmtc3
Name: transmembrane and tetratricopeptide repeat containing 3
Synonyms: 9130014E20Rik, B130008E12Rik, mSmile
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 237500
Homologene: 27616
Prune2
Name: prune homolog 2
Synonyms: 6330414G02Rik, A330102H22Rik, A230083H22Rik, Olfaxin
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 353211
VEGA: 19
Homologene: 18939
Map2
Name: microtubule-associated protein 2
Synonyms: MAP-2, G1-397-34, Mtap2, repro4
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 17756
HGNC: HGNC:6839
Homologene: 1779
Yme1l1
Name: YME1-like 1 (S. cerevisiae)
Synonyms: Ftsh, ATP-dependent metalloprotease FtsH1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 27377
Homologene: 31996
Tmprss2
Name: transmembrane protease, serine 2
Synonyms: epitheliasin, D16Ertd61e
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 50528
VEGA: 16
Homologene: 4136
Ackr4
Name: atypical chemokine receptor 4
Synonyms: VSHK1, CCR11, CCBP2, PPR1, CCX-CKR, A630091E18Rik, Ccrl1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 252837
HGNC: HGNC:1611
Homologene: 49474
Ttn
Name: titin
Synonyms: connectin, L56, mdm, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Crb1
Name: crumbs family member 1, photoreceptor morphogenesis associated
Synonyms: A930008G09Rik, 7530426H14Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 170788
HGNC: HGNC:2343
Homologene: 8092
Aff3
Name: AF4/FMR2 family, member 3
Synonyms: LAF-4, 3222402O04Rik, Laf4
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16764
HGNC: HGNC:6473
Homologene: 1718
Hivep2
Name: human immunodeficiency virus type I enhancer binding protein 2
Synonyms: MIBP1, Schnurri-2, Shn-2, Gm20114
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 15273
HGNC: HGNC:4921
Homologene: 4900
Cyp2c66
Name: cytochrome P450, family 2, subfamily c, polypeptide 66
Synonyms: 2010301M18Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 69888
Homologene: 133566
Gls2
Name: glutaminase 2 (liver, mitochondrial)
Synonyms: Lga, A330074B06Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216456
Homologene: 40861
Ryr3
Name: ryanodine receptor 3
Synonyms: calcium release channel isoform 3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 20192
Homologene: 68151
Hc
Name: hemolytic complement
Synonyms: C5a, C5, He, Hfib2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 15139
HGNC: HGNC:1331
Homologene: 20412
Stx18
Name: syntaxin 18
Synonyms: 4933425D03Rik, 1810035L21Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 71116
Homologene: 9655
Scn5a
Name: sodium channel, voltage-gated, type V, alpha
Synonyms: Nav1.5c, Nav1.5, mH1, SkM2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 20271
Homologene: 22738
Wnk2
Name: WNK lysine deficient protein kinase 2
Synonyms: ESTM15, 1810073P09Rik, X83337
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 75607
Homologene: 19155
Pard3b
Name: par-3 family cell polarity regulator beta
Synonyms: 2810455B10Rik, PAR3beta, PAR3L, PAR3B, 2010002N16Rik, Als2cr19, 1810008K04Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 72823
Homologene: 35389
Gprc6a
Name: G protein-coupled receptor, family C, group 6, member A
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 210198
VEGA: 10
Homologene: 17529
Haus5
Name: HAUS augmin-like complex, subunit 5
Synonyms: 2310022K01Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 71909
Homologene: 18969
Or11g26
Name: olfactory receptor family 11 subfamily G member 26
Synonyms: GA_x6K02T2PMLR-6224293-6225228, MOR106-6, Olfr742
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 258422
Homologene: 74163
Ripor3
Name: RIPOR family member 3
Synonyms: 2310033K02Rik, Fam65c
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 69553
Homologene: 15438
Timm29
Name: translocase of inner mitochondrial membrane 29
Synonyms: 1810026J23Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 69773
Homologene: 34702
Dis3l
Name: DIS3 like exosome 3'-5' exoribonuclease
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 213550
Homologene: 15797
Spag16
Name: sperm associated antigen 16
Synonyms: Pf20, 4930524F24Rik, 4930585K05Rik, Wdr29, 4921511D23Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 66722
Homologene: 11572
Cts6
Name: cathepsin 6
Synonyms: 1600022N02Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 58518
Homologene: 75165
Nuggc
Name: nuclear GTPase, germinal center associated
Synonyms: LOC239151, SLIP-GC, Gm600
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 100503545
Homologene: 72641
Rbm42
Name: RNA binding motif protein 42
Synonyms: 1700003D06Rik, 3100004P22Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 68035
Homologene: 32579
Me1
Name: malic enzyme 1, NADP(+)-dependent, cytosolic
Synonyms: Mod-1, Mdh-1, D9Ertd267e, Mod1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 17436
HGNC: HGNC:6983
Homologene: 134785
Hars2
Name: histidyl-tRNA synthetase 2
Synonyms: HARSR, HO3, 4631412B19Rik, Harsl
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 70791
HGNC: HGNC:4817
Homologene: 40819
Ces4a
Name: carboxylesterase 4A
Synonyms: Ces8
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234677
Homologene: 71949
4933430I17Rik
Name: RIKEN cDNA 4933430I17 gene
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 214106
Homologene: 51897
Lmx1a
Name: LIM homeobox transcription factor 1 alpha
Synonyms: Lmx1.1, shaker short-tail
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 110648
HGNC: HGNC:6653
Homologene: 24921
Cherp
Name: calcium homeostasis endoplasmic reticulum protein
Synonyms: 5730408I11Rik, SCAF6, DAN16, D8Wsu96e
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 27967
Homologene: 4656
Trdn
Name: triadin
Synonyms: 2310045H21Rik, triadin-3, triadin-2, triadin-1, triadin 3, triadin 2, triadin 1, EG432451
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 76757
VEGA: 10
Homologene: 38137
Slc36a3
Name: solute carrier family 36 (proton/amino acid symporter), member 3
Synonyms: tramdorin2, PAT3, TRAMD2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 215332
Homologene: 76175
Hoxc8
Name: homeobox C8
Synonyms: Hox-3.1, D130011F21Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 15426
HGNC: HGNC:5129
Homologene: 130642
Ldc1
Name: leucine decarboxylase 1
Synonyms: LOC332942, Gm853
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 332942
Homologene: 128653
Hspa8
Name: heat shock protein 8
Synonyms: Hsp73, Hsc71, Hsc70, 2410008N15Rik, Hsc73
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 15481
HGNC: HGNC:5241
Homologene: 68524
Terb1
Name: telomere repeat binding bouquet formation protein 1
Synonyms: 4930532D21Rik, Ccdc79
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 320022
Homologene: 18330
Or13p10
Name: olfactory receptor family 13 subfamily P member 10
Synonyms: IH12, MOR258-5, GA_x6K02T2QD9B-18877756-18876809, Olfr62
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 18363
Hoxd13
Name: homeobox D13
Synonyms: Hox-4.8, spdh
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 15433
HGNC: HGNC:5136
Homologene: 20147
Ier5l
Name: immediate early response 5-like
Synonyms: 2610524G09Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 72500
Homologene: 69468
Guca2b
Name: guanylate cyclase activator 2b
Synonyms: uroguanylin, Gcap2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 14916
HGNC: HGNC:4683
Homologene: 5150
Trav5d-4
Name: T cell receptor alpha variable 5D-4
Synonyms: Gm8713
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 667583
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 38,205,054 bp
  • C to A, chromosome 1 at 62,637,798 bp
  • T to C, chromosome 1 at 66,415,113 bp
  • T to C, chromosome 1 at 69,895,248 bp
  • T to A, chromosome 1 at 139,237,267 bp
  • G to T, chromosome 1 at 156,884,540 bp
  • A to G, chromosome 1 at 167,689,803 bp
  • T to G, chromosome 2 at 5,229,037 bp
  • C to T, chromosome 2 at 23,164,585 bp
  • C to A, chromosome 2 at 30,472,849 bp
  • G to A, chromosome 2 at 35,012,898 bp
  • G to T, chromosome 2 at 74,668,317 bp
  • A to G, chromosome 2 at 76,833,718 bp
  • T to A, chromosome 2 at 112,662,510 bp
  • T to C, chromosome 2 at 167,983,199 bp
  • T to A, chromosome 2 at 181,718,924 bp
  • T to C, chromosome 4 at 40,186,376 bp
  • T to A, chromosome 4 at 62,543,741 bp
  • A to C, chromosome 4 at 118,666,407 bp
  • T to C, chromosome 4 at 119,658,804 bp
  • C to T, chromosome 4 at 130,215,363 bp
  • T to A, chromosome 5 at 38,128,106 bp
  • G to A, chromosome 5 at 115,609,862 bp
  • A to T, chromosome 6 at 29,558,833 bp
  • T to A, chromosome 6 at 114,686,096 bp
  • A to G, chromosome 7 at 19,014,184 bp
  • T to C, chromosome 7 at 28,883,201 bp
  • T to A, chromosome 7 at 30,645,157 bp
  • T to A, chromosome 7 at 30,659,559 bp
  • A to T, chromosome 7 at 46,909,060 bp
  • T to C, chromosome 7 at 116,418,048 bp
  • G to A, chromosome 7 at 141,640,258 bp
  • A to G, chromosome 8 at 21,948,546 bp
  • G to A, chromosome 8 at 72,462,008 bp
  • A to T, chromosome 8 at 104,484,371 bp
  • G to A, chromosome 8 at 105,148,082 bp
  • A to G, chromosome 9 at 21,593,705 bp
  • T to G, chromosome 9 at 40,802,601 bp
  • T to C, chromosome 9 at 64,311,830 bp
  • C to T, chromosome 9 at 86,619,737 bp
  • A to G, chromosome 9 at 104,099,461 bp
  • A to G, chromosome 9 at 119,535,964 bp
  • T to C, chromosome 10 at 14,128,267 bp
  • A to G, chromosome 10 at 33,444,078 bp
  • A to T, chromosome 10 at 51,627,259 bp
  • T to C, chromosome 10 at 80,064,387 bp
  • T to A, chromosome 10 at 100,447,434 bp
  • A to G, chromosome 10 at 128,201,285 bp
  • A to G, chromosome 11 at 55,148,583 bp
  • T to C, chromosome 11 at 80,638,074 bp
  • A to G, chromosome 12 at 8,011,135 bp
  • A to T, chromosome 13 at 49,095,438 bp
  • A to T, chromosome 13 at 61,195,468 bp
  • T to A, chromosome 13 at 73,612,428 bp
  • T to C, chromosome 14 at 50,515,558 bp
  • G to A, chromosome 14 at 53,001,751 bp
  • G to A, chromosome 14 at 65,641,282 bp
  • A to T, chromosome 14 at 75,740,563 bp
  • A to G, chromosome 15 at 102,991,111 bp
  • T to C, chromosome 16 at 93,771,787 bp
  • T to A, chromosome 16 at 97,568,465 bp
  • A to G, chromosome 18 at 36,789,235 bp
  • T to G, chromosome 19 at 17,121,265 bp
  • T to A, chromosome 19 at 39,186,462 bp
  • A to G, chromosome 19 at 53,002,472 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R8329 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
067859-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.