Strain Name:
C57BL/6J-MtgxR8929Btlr/Mmmh
Stock Number:
068773-MU
Citation ID:
RRID:MMRRC_068773-MU
Other Names:
R8929 (G1)
Major Collection:

Strain Information

B4galt6
Name: UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 6
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 56386
VEGA: 18
HGNC: HGNC:929
Homologene: 3506
Cdh1
Name: cadherin 1
Synonyms: E-cadherin, Ecad, UM, uvomorulin, L-CAM, E-cad
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 12550
HGNC: HGNC:1748
Homologene: 20917
Sod2
Name: superoxide dismutase 2, mitochondrial
Synonyms: MnSOD, manganese SOD, manganese superoxide dismutase, Sod-2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 20656
VEGA: 17
Homologene: 530
Hgf
Name: hepatocyte growth factor
Synonyms: scatter factor, NK1, SF/HGF, HGF/SF, NK2, C230052L06Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 15234
HGNC: HGNC:4893
Homologene: 503
Epyc
Name: epiphycan
Synonyms: PG-Lb, epiphycan, SLRR3B, Dspg3
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 13516
HGNC: HGNC:3053
Homologene: 3634
Lefty1
Name: left right determination factor 1
Synonyms: lefty-1, Stra3, Lefty, Ebaf
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 13590
HGNC: HGNC:6552
Homologene: 49231
Pds5b
Name: PDS5 cohesin associated factor B
Synonyms: AS3, Aprin
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100710
Homologene: 41001
Gdf3
Name: growth differentiation factor 3
Synonyms: Gdf-3, Vgr-2, Vgr2, ecat9
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 14562
HGNC: HGNC:4218
Homologene: 7336
Tut7
Name: terminal uridylyl transferase 7
Synonyms: 6030448M23Rik, Tent3b, Zcchc6
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 214290
VEGA: 13
Homologene: 51941
Kat7
Name: K(lysine) acetyltransferase 7
Synonyms: Hbo1, Hboa, Myst2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217127
Homologene: 5134
Ncapg2
Name: non-SMC condensin II complex, subunit G2
Synonyms: Mtb, 5830426I05Rik, Luzp5, mCAP-G2
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 76044
VEGA: 12
Homologene: 9820
Akap13
Name: A kinase anchor protein 13
Synonyms: AKAP-Lbc, PROTO-LBC, PROTO-LB, Ht31, 5730522G15Rik, 1700026G02Rik, 5830460E08Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 75547
HGNC: HGNC:371
Homologene: 4903
Metap1
Name: methionyl aminopeptidase 1
Synonyms: 1700029C17Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 75624
Homologene: 6488
Ptpn21
Name: protein tyrosine phosphatase, non-receptor type 21
Synonyms: PTPD1, PTPRL10
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 24000
VEGA: 12
HGNC: HGNC:9651
Homologene: 5110
Atxn2l
Name: ataxin 2-like
Synonyms: A2RP, A2LG, A2D, A2lp
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233871
Homologene: 16513
Adrm1
Name: adhesion regulating molecule 1 26S proteasome ubiquitin receptor
Synonyms: ARM-1, 2510006J17Rik, Gp110, 1110063P18Rik, Rpn13
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 56436
Homologene: 10513
Nars1
Name: asparaginyl-tRNA synthetase 1
Synonyms: ASNRS, Nars
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 70223
VEGA: 18
HGNC: HGNC:7643
Homologene: 68404
Pole
Name: polymerase (DNA directed), epsilon
Synonyms: pol-epsilon
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 18973
HGNC: HGNC:9177
Homologene: 4539
Fndc3b
Name: fibronectin type III domain containing 3B
Synonyms: 1600019O04Rik, fad104
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 72007
Homologene: 11244
Tfap2a
Name: transcription factor AP-2, alpha
Synonyms: Ap-2 (a), AP-2 alpha, Ap2tf, Ap2, Tcfap2a, AP2alpha
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 21418
VEGA: 13
Homologene: 2421
Slc39a7
Name: solute carrier family 39 (zinc transporter), member 7
Synonyms: Ke-4, H-2Ke4, KE4, Ring5, H2-Ke4, Zip7
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 14977
HGNC: HGNC:4927
Homologene: 5072
Mcm4
Name: minichromosome maintenance complex component 4
Synonyms: mCdc21, Cdc21, Mcmd4, 19G
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 17217
VEGA: 16
HGNC: HGNC:6947
Homologene: 40496
Azi2
Name: 5-azacytidine induced gene 2
Synonyms: AZ2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 27215
Homologene: 8443
Sec24b
Name: SEC24 homolog B, COPII coat complex component
Synonyms: SEC24
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99683
Homologene: 55968
Grwd1
Name: glutamate-rich WD repeat containing 1
Synonyms: WDR28
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 101612
Homologene: 6644
Zfp445
Name: zinc finger protein 445
Synonyms: ZNF168
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235682
VEGA: 9
Homologene: 27832
Slain1
Name: SLAIN motif family, member 1
Synonyms: 9630044O09Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 105439
Homologene: 16943
Slc44a4
Name: solute carrier family 44, member 4
Synonyms: NG22, 2210409B01Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 70129
Homologene: 11359
Ptpn4
Name: protein tyrosine phosphatase, non-receptor type 4
Synonyms: hPTP-MEG, protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte), TEP/mPTPMEG, testis-enriched phosphatase, TEP, PTPMEG
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 19258
HGNC: HGNC:9656
Homologene: 2120
Clec4b1
Name: C-type lectin domain family 4, member b1
Synonyms: 1810046I24Rik, 1810046I24Rik, DCARbeta, DCAR, mDcar2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 69810
Homologene: 130350
Trpc6
Name: transient receptor potential cation channel, subfamily C, member 6
Synonyms: mtrp6, Trrp6
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 22068
VEGA: 9
Homologene: 37944
Ern2
Name: endoplasmic reticulum to nucleus signalling 2
Synonyms: Ire1b
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 26918
Homologene: 22687
Cdipt
Name: CDP-diacylglycerol--inositol 3-phosphatidyltransferase
Synonyms: 9530042F15Rik, D7Bwg0575e
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 52858
HGNC: HGNC:1769
Homologene: 7159
Ttn
Name: titin
Synonyms: connectin, L56, mdm, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Muc4
Name: mucin 4
Synonyms: 4933405I11Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 140474
HGNC: HGNC:7514
Homologene: 124469
Fstl5
Name: follistatin-like 5
Synonyms: 9130207J01Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 213262
Homologene: 10584
Tbx15
Name: T-box 15
Synonyms: Tbx8, de, Tbx14
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 21384
Homologene: 7967
Trank1
Name: tetratricopeptide repeat and ankyrin repeat containing 1
Synonyms: A230061D21Rik, LOC235639, C030048J01Rik, Lba1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 320429
Homologene: 45845
Fras1
Name: Fraser extracellular matrix complex subunit 1
Synonyms: bl, E130113P14Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231470
Homologene: 23516
Slc5a4a
Name: solute carrier family 5, member 4a
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 64452
VEGA: 10
Unc13a
Name: unc-13 homolog A
Synonyms: Munc13-1, 2410078G03Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 382018
Homologene: 11279
Nebl
Name: nebulette
Synonyms: Lnebl, 1200007O21Rik, A630080F05Rik, D830029A09Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 74103
Homologene: 128431
Vmn2r82
Name: vomeronasal 2, receptor 82
Synonyms: EG624845
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 624845
Homologene: 83483
Bdh1
Name: 3-hydroxybutyrate dehydrogenase, type 1
Synonyms: 2310032J20Rik, Bdh
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 71911
HGNC: HGNC:1027
Homologene: 20860
Arfgef3
Name: ARFGEF family member 3
Synonyms: B930094H20Rik, D10Bwg1379e, BIG3
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 215821
VEGA: 10
Homologene: 41366
Sema5b
Name: sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
Synonyms: SemG, SemG, Semag
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 20357
Homologene: 8427
Cyp2j5
Name: cytochrome P450, family 2, subfamily j, polypeptide 5
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 13109
HGNC: HGNC:2634
Homologene: 116530
Sytl2
Name: synaptotagmin-like 2
Synonyms: Slp2, Slp2-a, Slp2-d, Slp2-c, Slp2-b
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 83671
Homologene: 131343
Spart
Name: spartin
Synonyms: TAHCCP1, Spg20
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229285
Agxt2
Name: alanine-glyoxylate aminotransferase 2
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 268782
Homologene: 12887
Zer1
Name: zyg-11 related, cell cycle regulator
Synonyms: C230075L19Rik, Zyg11bl
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227693
Homologene: 4621
BC051019
Name: cDNA sequence BC051019
Synonyms: D7H11orf16, ICRFP703N2430Q5.5
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 57355
HGNC: HGNC:1169
Homologene: 49631
Clip4
Name: CAP-GLY domain containing linker protein family, member 4
Synonyms: 1700074B05Rik, 5830409B12Rik, 4833417L20Rik, 1700024K14Rik, Rsnl2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 78785
VEGA: 17
Homologene: 11662
Lrriq3
Name: leucine-rich repeats and IQ motif containing 3
Synonyms: 4930438B07Rik, 4930511J15Rik, 4933403H06Rik, Lrrc44
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 74435
Homologene: 23668
Slc36a3
Name: solute carrier family 36 (proton/amino acid symporter), member 3
Synonyms: tramdorin2, PAT3, TRAMD2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 215332
Homologene: 76175
Vmn1r212
Name: vomeronasal 1 receptor 212
Synonyms: V1rh18
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 171275
Homologene: 110880
Cndp2
Name: CNDP dipeptidase 2
Synonyms: Pep-1, Dip-2, 0610010E05Rik, Cn2, Pep1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 66054
VEGA: 18
Homologene: 10085
Dppa5a
Name: developmental pluripotency associated 5A
Synonyms: Esg1, ecat2, Dppa5
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 434423
Homologene: 104905
Pdap1
Name: PDGFA associated protein 1
Synonyms: HASPP28, PAP1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231887
Homologene: 8927
Dpf1
Name: double PHD fingers 1
Synonyms: neuro-d4, Neud4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 29861
Homologene: 3415
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 119,667,548 bp
  • A to G, chromosome 1 at 180,937,725 bp
  • C to A, chromosome 2 at 17,393,180 bp
  • A to G, chromosome 2 at 30,110,869 bp
  • A to T, chromosome 2 at 76,876,580 bp
  • A to G, chromosome 2 at 180,172,937 bp
  • C to T, chromosome 3 at 27,542,104 bp
  • T to C, chromosome 3 at 55,128,558 bp
  • T to C, chromosome 3 at 76,707,831 bp
  • T to A, chromosome 3 at 99,314,903 bp
  • T to C, chromosome 3 at 130,009,858 bp
  • T to C, chromosome 3 at 138,468,882 bp
  • T to C, chromosome 3 at 155,188,182 bp
  • T to C, chromosome 4 at 96,658,740 bp
  • G to T, chromosome 5 at 16,593,990 bp
  • T to C, chromosome 5 at 96,769,507 bp
  • T to C, chromosome 5 at 110,297,788 bp
  • T to C, chromosome 5 at 145,132,862 bp
  • T to C, chromosome 5 at 150,719,914 bp
  • C to T, chromosome 6 at 122,609,797 bp
  • G to T, chromosome 6 at 123,069,769 bp
  • A to T, chromosome 7 at 29,309,749 bp
  • A to T, chromosome 7 at 45,830,632 bp
  • T to C, chromosome 7 at 75,609,004 bp
  • C to T, chromosome 7 at 90,375,602 bp
  • C to T, chromosome 7 at 109,716,026 bp
  • C to T, chromosome 7 at 122,170,140 bp
  • C to G, chromosome 7 at 126,493,756 bp
  • T to G, chromosome 7 at 126,979,653 bp
  • T to C, chromosome 8 at 71,651,191 bp
  • ACTCGAAATGATGTGGCTC to ACTC, chromosome 8 at 106,666,238 bp
  • A to G, chromosome 9 at 8,643,410 bp
  • A to G, chromosome 9 at 78,367,883 bp
  • T to A, chromosome 9 at 111,378,935 bp
  • C to A, chromosome 9 at 118,049,976 bp
  • T to G, chromosome 9 at 122,853,667 bp
  • T to A, chromosome 10 at 18,603,455 bp
  • A to G, chromosome 10 at 76,170,783 bp
  • A to G, chromosome 10 at 79,396,707 bp
  • A to G, chromosome 10 at 97,675,745 bp
  • A to G, chromosome 11 at 55,137,311 bp
  • T to C, chromosome 11 at 95,306,156 bp
  • A to T, chromosome 12 at 98,689,137 bp
  • A to T, chromosome 12 at 116,452,363 bp
  • T to A, chromosome 13 at 22,883,324 bp
  • A to G, chromosome 13 at 40,728,832 bp
  • A to G, chromosome 13 at 59,800,128 bp
  • A to T, chromosome 14 at 103,685,728 bp
  • C to A, chromosome 15 at 10,393,744 bp
  • T to A, chromosome 16 at 15,630,425 bp
  • G to A, chromosome 16 at 31,456,894 bp
  • T to G, chromosome 16 at 32,753,994 bp
  • A to T, chromosome 16 at 32,754,017 bp
  • C to A, chromosome 16 at 35,647,367 bp
  • C to A, chromosome 17 at 13,015,087 bp
  • T to C, chromosome 17 at 34,030,990 bp
  • A to T, chromosome 17 at 34,917,532 bp
  • T to C, chromosome 17 at 71,831,208 bp
  • A to G, chromosome 18 at 20,688,365 bp
  • G to T, chromosome 18 at 64,511,824 bp
  • A to G, chromosome 18 at 84,675,173 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R8929 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
068773-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.