Strain Name:
C57BL/6J-MtgxR8969Btlr/Mmmh
Stock Number:
068803-MU
Citation ID:
RRID:MMRRC_068803-MU
Other Names:
R8969 (G1)
Major Collection:

Strain Information

Kit
Name: KIT proto-oncogene receptor tyrosine kinase
Synonyms: SCO1, Steel Factor Receptor, belly-spot, SCO5, Tr-kit, Dominant white spotting, Gsfsco1, SOW3, c-KIT, CD117, Gsfsco5, Gsfsow3
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 16590
HGNC: HGNC:6342
Homologene: 187
Kmt2c
Name: lysine (K)-specific methyltransferase 2C
Synonyms: E330008K23Rik, HALR, Mll3
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231051
Homologene: 46480
Dspp
Name: dentin sialophosphoprotein
Synonyms: Dpp, Dsp, Dmp3
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 666279
HGNC: HGNC:3054
Chrnb2
Name: cholinergic receptor nicotinic beta 2 subunit
Synonyms: Acrb2, [b]2-nAchR, Acrb-2, C030030P04Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 11444
HGNC: HGNC:1962
Homologene: 595
Crkl
Name: v-crk avian sarcoma virus CT10 oncogene homolog-like
Synonyms: 1110025F07Rik, Crkol, snoop
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 12929
HGNC: HGNC:2363
Homologene: 38021
Aldh1l1
Name: aldehyde dehydrogenase 1 family, member L1
Synonyms: Fthfd, 1810048F20Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 107747
HGNC: HGNC:3978
Homologene: 122031
Srd5a3
Name: steroid 5 alpha-reductase 3
Synonyms: Srd5a2l, 1110025P14Rik, D730040M03Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 57357
Homologene: 41385
Kat2b
Name: K(lysine) acetyltransferase 2B
Synonyms: Pcaf, A930006P13Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 18519
HGNC: HGNC:8638
Homologene: 20834
Zfp809
Name: zinc finger protein 809
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235047
VEGA: 9
Rnf38
Name: ring finger protein 38
Synonyms: 2610202O07Rik, 1700065B19Rik, Oip1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 73469
Homologene: 32550
Zranb3
Name: zinc finger, RAN-binding domain containing 3
Synonyms: 4933425L19Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226409
Homologene: 32770
Ppp2r5e
Name: protein phosphatase 2, regulatory subunit B', epsilon
Synonyms: 4633401M22Rik, protein phosphatase 2A subunit beta, B56beta
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 26932
VEGA: 12
HGNC: HGNC:9313
Homologene: 55962
Fcho2
Name: FCH domain only 2
Synonyms: 5832424M12Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218503
VEGA: 13
Homologene: 9030
Sec62
Name: SEC62 homolog, preprotein translocation
Synonyms: Dtrp1, Tloc1, 3100002M17Rik, SEC62, HTP1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 69276
Homologene: 2449
Xrn2
Name: 5'-3' exoribonuclease 2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 24128
Homologene: 6927
Ptpn21
Name: protein tyrosine phosphatase, non-receptor type 21
Synonyms: PTPRL10, PTPD1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 24000
VEGA: 12
HGNC: HGNC:9651
Homologene: 5110
Med27
Name: mediator complex subunit 27
Synonyms: D2Ertd434e, 1500015J03Rik, 2310042P07Rik, Crsp8
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 68975
HGNC: HGNC:2377
Homologene: 3152
Phip
Name: pleckstrin homology domain interacting protein
Synonyms: 4632404O06Rik, 2810004D21Rik, Ndrp, Wdr11
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 83946
Homologene: 41209
Tenm2
Name: teneurin transmembrane protein 2
Synonyms: D3Bwg1534e, Ten-m2, 9330187F13Rik, Odz2, 2610040L17Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 23964
Homologene: 22672
Ptcd3
Name: pentatricopeptide repeat domain 3
Synonyms: 2610034F17Rik, 2810422B04Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 69956
Homologene: 41211
Ccdc167
Name: coiled-coil domain containing 167
Synonyms: 1110021J02Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 68597
Homologene: 79796
Ash1l
Name: ASH1 like histone lysine methyltransferase
Synonyms: chromatin remodeling factor, E430018P19Rik, KMT2H, 8030453L17Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 192195
Homologene: 10225
Pcbp2
Name: poly(rC) binding protein 2
Synonyms: alphaCP-2, Hnrpx
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 18521
VEGA: 15
HGNC: HGNC:8648
Homologene: 74536
Ifnar2
Name: interferon (alpha and beta) receptor 2
Synonyms: Ifnar-2
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 15976
HGNC: HGNC:5433
Homologene: 49242
Krt10
Name: keratin 10
Synonyms: D130054E02Rik, cytokeratin 10, K1C1, Krt1-10, K10, keratin 10, suprabasal cytokeratin 10, Krt-1.10
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16661
HGNC: HGNC:6413
Homologene: 137236
Sec1
Name: secretory blood group 1
Synonyms: GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase FUT-III, Fut3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 56546
Homologene: 431
Jup
Name: junction plakoglobin
Synonyms: plakoglobin, Ctnng, D930025P04Rik, gamma-catenin, PG
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16480
HGNC: HGNC:6207
Homologene: 1680
Adam33
Name: a disintegrin and metallopeptidase domain 33
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 110751
Homologene: 11881
U2af1
Name: U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1
Synonyms: 2010107D16Rik, 35kDa
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 108121
VEGA: 17
Homologene: 14345
Uimc1
Name: ubiquitin interaction motif containing 1
Synonyms: D330018D10Rik, Rxrip110, D630032M02Rik, 9430016E08Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 20184
Homologene: 9455
Dync2h1
Name: dynein cytoplasmic 2 heavy chain 1
Synonyms: DHC1b, DHC2, b2b414Clo, Dnchc2, 4432416O06Rik, D330044F14Rik, D030010H02Rik, m152Asp, m407Asp
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 110350
HGNC: HGNC:2962
Homologene: 14468
D16Ertd472e
Name: DNA segment, Chr 16, ERATO Doi 472, expressed
Synonyms: E330003K22Rik, 2310009O17Rik, 1700010I10Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 67102
Homologene: 9696
Btbd10
Name: BTB domain containing 10
Synonyms: Gmrp1, 1110056N09Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 68815
Homologene: 13009
Palld
Name: palladin, cytoskeletal associated protein
Synonyms: 2410003B16Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 72333
Homologene: 75052
Terf2ip
Name: telomeric repeat binding factor 2, interacting protein
Synonyms: Rap1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 57321
Homologene: 10357
Nceh1
Name: neutral cholesterol ester hydrolase 1
Synonyms: CPO-BP, mKIAA1363, B230106I24Rik, Aadacl1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 320024
Homologene: 23251
Isl1
Name: ISL1 transcription factor, LIM/homeodomain
Synonyms: Islet 1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 16392
HGNC: HGNC:6132
Homologene: 1661
Abca13
Name: ATP-binding cassette, sub-family A member 13
Synonyms: A930002G16Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 268379
Homologene: 27991
Pclo
Name: piccolo (presynaptic cytomatrix protein)
Synonyms: Pico, Acz
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 26875
Homologene: 69111
Trpm3
Name: transient receptor potential cation channel, subfamily M, member 3
Synonyms: B930001P07Rik, 6330504P12Rik, LTRPC3, melastatin 2, MLSN2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226025
VEGA: 19
Homologene: 62287
Decr2
Name: 2-4-dienoyl-Coenzyme A reductase 2, peroxisomal
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 26378
HGNC: HGNC:2754
Homologene: 22223
Sh3rf1
Name: SH3 domain containing ring finger 1
Synonyms: Posh, 2200003J05Rik, Sh3md2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 59009
Homologene: 10988
Cfap206
Name: cilia and flagella associated protein 206
Synonyms: 1700003M02Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 69329
Homologene: 18713
Helz2
Name: helicase with zinc finger 2, transcriptional coactivator
Synonyms: BC006779
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 229003
Homologene: 14118
Hc
Name: hemolytic complement
Synonyms: C5, C5a, Hfib2, He
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 15139
HGNC: HGNC:1331
Homologene: 20412
Gm5114
Name: predicted gene 5114
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 330513
Homologene: 45597
Cdh12
Name: cadherin 12
Synonyms: Br-cadherin
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 215654
HGNC: HGNC:1751
Homologene: 37873
Atg9b
Name: autophagy related 9B
Synonyms: eONE, LOC213948, Apg9l2, Nos3as
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 213948
Homologene: 72638
Arhgef11
Name: Rho guanine nucleotide exchange factor 11
Synonyms: PDZ-RhoGEF, Prg
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 213498
Homologene: 11409
Or5m10b
Name: olfactory receptor family 5 subfamily M member 10B
Synonyms: MOR196-1, Olfr1022, GA_x6K02T2Q125-47347069-47348016
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258582
Homologene: 128086
Kif2b
Name: kinesin family member 2B
Synonyms: 1700063D03Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 73470
Homologene: 23775
Vmn2r83
Name: vomeronasal 2, receptor 83
Synonyms: EG625029
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 625029
Homologene: 83669
Cmah
Name: cytidine monophospho-N-acetylneuraminic acid hydroxylase
Synonyms: CMP-NeuAc hydroxylase
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 12763
HGNC: HGNC:2098
Homologene: 7269
Zfp735
Name: zinc finger protein 735
Synonyms: 1700012C15Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 76390
Homologene: 88945
Phldb2
Name: pleckstrin homology like domain, family B, member 2
Synonyms: LL5b, C820004H04Rik, LL5beta
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 208177
Homologene: 17100
Or51a39
Name: olfactory receptor family 51 subfamily A member 39
Synonyms: Olfr33, MOR11-2, GA_x6K02T2PBJ9-5431102-5430146, MTPCR33
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18332
Homologene: 81534
Zbtb6
Name: zinc finger and BTB domain containing 6
Synonyms: Zfp482, A830092L04Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241322
Homologene: 4829
Acp7
Name: acid phosphatase 7, tartrate resistant
Synonyms: Papl, C330005M16Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 101744
Homologene: 23924
Zdhhc14
Name: zinc finger, DHHC domain containing 14
Synonyms: New1cp, B530001K09Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224454
VEGA: 17
Homologene: 62301
Cyp3a59
Name: cytochrome P450, family 3, subfamily a, polypeptide 59
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100041449
Homologene: 135775
Eno3
Name: enolase 3, beta muscle
Synonyms: Eno-3
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 13808
HGNC: HGNC:3354
Homologene: 68215
Tmc1
Name: transmembrane channel-like gene family 1
Synonyms: Beethoven, 4933416G09Rik, Bth
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 13409
VEGA: 19
Homologene: 23670
Ak3
Name: adenylate kinase 3
Synonyms: AK-3
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 56248
Homologene: 21744
Tmtc4
Name: transmembrane and tetratricopeptide repeat containing 4
Synonyms: 4930403J22Rik, 5730419O14Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 70551
Homologene: 32796
Krt36
Name: keratin 36
Synonyms: HRa-1, keratin 5, Krt1-5, Krt1-22
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16673
HGNC: HGNC:6454
Homologene: 88459
Suox
Name: sulfite oxidase
Synonyms: SO
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 211389
VEGA: 10
Homologene: 394
Ndufs3
Name: NADH:ubiquinone oxidoreductase core subunit S3
Synonyms: 0610010M09Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 68349
HGNC: HGNC:7710
Homologene: 3346
Klhl36
Name: kelch-like 36
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234796
Homologene: 32598
Nfxl1
Name: nuclear transcription factor, X-box binding-like 1
Synonyms: D430033A06Rik, LOC381696, TCF9, 1700012H24Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100978
Homologene: 26752
Mylip
Name: myosin regulatory light chain interacting protein
Synonyms: Idol, 9430057C20Rik, Mir
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218203
VEGA: 13
Homologene: 8309
Klk1b27
Name: kallikrein 1-related peptidase b27
Synonyms: Klk21l, Klk27, mGK-27
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 16619
Homologene: 68141
Tmprss11e
Name: transmembrane protease, serine 11e
Synonyms: DESC1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 243084
Homologene: 8543
Or5as1
Name: olfactory receptor family 5 subfamily AS member 1
Synonyms: GA_x6K02T2Q125-48635468-48634530, MOR181-2, Olfr1111
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258586
Homologene: 74238
Ambp
Name: alpha 1 microglobulin/bikunin precursor
Synonyms: HI-30, UTI, Urinary Trypsin Inhibitor, ulinastatin, Itil, Intin4, ASPI
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 11699
HGNC: HGNC:453
Homologene: 1234
Or51f1e
Name: olfactory receptor family 51 subfamily F member 1E
Synonyms: Olfr585, GA_x6K02T2PBJ9-5809085-5810035, MOR14-4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259091
Homologene: 133721
Serpinb2
Name: serine (or cysteine) peptidase inhibitor, clade B, member 2
Synonyms: ovalbumin, PAI-2, Planh2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 18788
HGNC: HGNC:8584
Homologene: 20571
Mxd1
Name: MAX dimerization protein 1
Synonyms: Mad, Mad1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 17119
HGNC: HGNC:6761
Homologene: 1767
Tnfrsf22
Name: tumor necrosis factor receptor superfamily, member 22
Synonyms: mDcTrailr2, 2810028K06Rik, SOBa, C130035G06Rik, Tnfrh2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 79202
Homologene: 84848
Mettl25b
Name: methyltransferase like 25B
Synonyms: Rrnad1, BC023814
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229503
Homologene: 9332
Clic1
Name: chloride intracellular channel 1
Synonyms: Clcp, G6
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 114584
HGNC: HGNC:2062
Homologene: 20343
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 107,524,660 bp
  • A to T, chromosome 1 at 127,960,851 bp
  • G to T, chromosome 2 at 29,346,863 bp
  • A to G, chromosome 2 at 35,019,463 bp
  • A to G, chromosome 2 at 37,428,665 bp
  • A to G, chromosome 2 at 85,869,488 bp
  • T to A, chromosome 2 at 87,150,584 bp
  • A to T, chromosome 2 at 90,902,429 bp
  • C to T, chromosome 2 at 131,053,074 bp
  • T to C, chromosome 2 at 147,029,384 bp
  • A to G, chromosome 2 at 181,237,788 bp
  • T to A, chromosome 3 at 27,222,736 bp
  • A to G, chromosome 3 at 30,818,875 bp
  • T to C, chromosome 3 at 87,725,642 bp
  • G to A, chromosome 3 at 87,929,975 bp
  • T to C, chromosome 3 at 88,966,291 bp
  • A to G, chromosome 3 at 89,757,225 bp
  • A to T, chromosome 4 at 34,692,522 bp
  • A to T, chromosome 4 at 44,149,079 bp
  • C to T, chromosome 4 at 63,154,091 bp
  • T to A, chromosome 5 at 14,522,194 bp
  • C to T, chromosome 5 at 24,387,834 bp
  • T to A, chromosome 5 at 25,314,389 bp
  • A to C, chromosome 5 at 72,559,130 bp
  • G to A, chromosome 5 at 75,639,062 bp
  • A to G, chromosome 5 at 76,153,646 bp
  • T to A, chromosome 5 at 86,713,899 bp
  • A to T, chromosome 5 at 104,177,774 bp
  • A to T, chromosome 5 at 146,112,820 bp
  • T to C, chromosome 6 at 71,903,447 bp
  • C to T, chromosome 6 at 86,651,484 bp
  • A to G, chromosome 6 at 90,570,808 bp
  • G to A, chromosome 7 at 28,607,957 bp
  • C to A, chromosome 7 at 39,409,308 bp
  • T to A, chromosome 7 at 44,054,508 bp
  • A to G, chromosome 7 at 45,679,473 bp
  • T to C, chromosome 7 at 102,714,351 bp
  • T to G, chromosome 7 at 103,098,044 bp
  • A to T, chromosome 7 at 113,325,955 bp
  • T to A, chromosome 7 at 143,638,436 bp
  • A to C, chromosome 8 at 61,384,826 bp
  • T to A, chromosome 8 at 61,684,849 bp
  • A to G, chromosome 8 at 112,011,738 bp
  • T to C, chromosome 8 at 119,870,148 bp
  • T to C, chromosome 9 at 7,130,723 bp
  • T to C, chromosome 9 at 22,225,834 bp
  • T to C, chromosome 9 at 82,926,964 bp
  • A to G, chromosome 10 at 79,478,019 bp
  • T to C, chromosome 10 at 128,671,673 bp
  • T to A, chromosome 11 at 9,277,944 bp
  • C to T, chromosome 11 at 36,051,861 bp
  • T to A, chromosome 11 at 70,660,865 bp
  • T to A, chromosome 11 at 73,711,873 bp
  • T to C, chromosome 11 at 91,577,193 bp
  • T to A, chromosome 11 at 99,387,608 bp
  • T to A, chromosome 11 at 100,102,303 bp
  • C to T, chromosome 11 at 100,379,565 bp
  • G to T, chromosome 12 at 75,453,718 bp
  • T to A, chromosome 12 at 98,689,025 bp
  • A to G, chromosome 13 at 24,422,653 bp
  • T to A, chromosome 13 at 45,391,344 bp
  • A to G, chromosome 13 at 55,085,634 bp
  • A to T, chromosome 13 at 98,755,096 bp
  • A to G, chromosome 13 at 116,303,321 bp
  • T to C, chromosome 14 at 122,941,812 bp
  • A to G, chromosome 15 at 21,492,653 bp
  • T to G, chromosome 15 at 102,490,779 bp
  • A to G, chromosome 16 at 17,469,054 bp
  • A to T, chromosome 16 at 45,772,133 bp
  • T to G, chromosome 16 at 78,547,794 bp
  • T to C, chromosome 16 at 91,404,172 bp
  • C to T, chromosome 17 at 5,725,280 bp
  • T to A, chromosome 17 at 26,087,381 bp
  • T to C, chromosome 17 at 29,705,579 bp
  • C to T, chromosome 17 at 31,648,880 bp
  • T to C, chromosome 17 at 35,055,410 bp
  • T to A, chromosome 17 at 53,660,088 bp
  • G to A, chromosome 19 at 20,816,229 bp
  • A to G, chromosome 19 at 22,925,944 bp
  • T to G, chromosome 19 at 29,047,694 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R8969 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
068803-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.