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Strain Name:
C57BL/6J-MtgxR9013Btlr/Mmmh
Stock Number:
068843-MU
Citation ID:
RRID:MMRRC_068843-MU
Other Names:
R9013 (G1)
Major Collection:

Strain Information

Meis1
Name: Meis homeobox 1
Synonyms: C530044H18Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17268
HGNC: HGNC:7000
Homologene: 86803
Snta1
Name: syntrophin, acidic 1
Synonyms: alpha1-syntrophin, Snt1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 20648
Homologene: 2331
Dst
Name: dystonin
Synonyms: bullous pemphigoid antigen 1, BPAG1-n, BPAG1, Bpag1, Bpag, ah, bullous pemphigoid antigen 1, athetoid, Macf2, 2310001O04Rik, nmf203, A830042E19Rik, nmf339
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 13518
HGNC: HGNC:1090
Homologene: 136716
Xrn1
Name: 5'-3' exoribonuclease 1
Synonyms: mXrn1, Dhm2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 24127
Homologene: 5894
Dgka
Name: diacylglycerol kinase, alpha
Synonyms: Dagk1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 13139
VEGA: 10
HGNC: HGNC:2849
Homologene: 1028
Nr5a2
Name: nuclear receptor subfamily 5, group A, member 2
Synonyms: Ftf, LRH-1, D1Ertd308e, UF2-H3B
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 26424
HGNC: HGNC:7984
Homologene: 20827
Trip11
Name: thyroid hormone receptor interactor 11
Synonyms: 3110031G15Rik, 2610511G22Rik, 6030460N08Rik, TRIP230, GMAP-210
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 109181
Homologene: 20897
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 34,178,084 bp
  • T to A, chromosome 1 at 52,011,798 bp
  • T to C, chromosome 1 at 91,552,441 bp
  • A to T, chromosome 1 at 136,945,007 bp
  • A to T, chromosome 1 at 158,520,500 bp
  • A to G, chromosome 1 at 171,214,457 bp
  • A to G, chromosome 1 at 174,222,608 bp
  • G to A, chromosome 1 at 176,824,805 bp
  • A to G, chromosome 2 at 11,727,765 bp
  • A to T, chromosome 2 at 154,403,889 bp
  • A to G, chromosome 2 at 158,437,140 bp
  • T to A, chromosome 3 at 34,650,597 bp
  • A to T, chromosome 3 at 98,852,661 bp
  • A to T, chromosome 4 at 14,506,514 bp
  • C to A, chromosome 4 at 52,935,900 bp
  • A to G, chromosome 4 at 65,992,347 bp
  • T to C, chromosome 5 at 14,677,613 bp
  • G to A, chromosome 5 at 35,976,588 bp
  • A to T, chromosome 5 at 90,523,735 bp
  • A to G, chromosome 5 at 120,805,432 bp
  • C to G, chromosome 5 at 128,602,305 bp
  • T to C, chromosome 5 at 135,911,363 bp
  • A to T, chromosome 5 at 140,463,613 bp
  • A to T, chromosome 6 at 118,742,305 bp
  • T to C, chromosome 7 at 18,524,765 bp
  • A to G, chromosome 7 at 28,398,708 bp
  • C to T, chromosome 7 at 29,915,292 bp
  • A to G, chromosome 7 at 30,317,993 bp
  • A to G, chromosome 7 at 44,140,908 bp
  • A to G, chromosome 7 at 44,865,561 bp
  • A to G, chromosome 7 at 98,145,345 bp
  • A to G, chromosome 7 at 108,095,264 bp
  • A to T, chromosome 7 at 140,466,266 bp
  • A to G, chromosome 8 at 4,250,620 bp
  • T to A, chromosome 8 at 11,222,270 bp
  • T to A, chromosome 9 at 18,512,773 bp
  • A to T, chromosome 9 at 18,988,578 bp
  • A to G, chromosome 9 at 21,105,107 bp
  • T to C, chromosome 9 at 44,849,911 bp
  • A to G, chromosome 9 at 96,038,928 bp
  • A to T, chromosome 9 at 111,468,498 bp
  • T to C, chromosome 10 at 21,007,759 bp
  • T to G, chromosome 10 at 39,922,066 bp
  • C to T, chromosome 10 at 103,215,070 bp
  • C to T, chromosome 10 at 112,271,818 bp
  • C to A, chromosome 10 at 128,730,202 bp
  • T to C, chromosome 10 at 129,659,833 bp
  • G to T, chromosome 11 at 19,016,354 bp
  • T to G, chromosome 11 at 23,370,302 bp
  • T to G, chromosome 11 at 33,623,491 bp
  • A to T, chromosome 11 at 50,207,857 bp
  • T to A, chromosome 11 at 63,083,858 bp
  • T to C, chromosome 11 at 96,039,300 bp
  • T to C, chromosome 11 at 119,038,823 bp
  • A to G, chromosome 12 at 16,739,969 bp
  • A to G, chromosome 12 at 76,795,344 bp
  • A to G, chromosome 12 at 101,885,118 bp
  • T to A, chromosome 13 at 11,603,732 bp
  • A to C, chromosome 13 at 43,168,834 bp
  • T to C, chromosome 13 at 50,247,552 bp
  • T to A, chromosome 13 at 81,669,461 bp
  • A to G, chromosome 14 at 53,717,147 bp
  • G to T, chromosome 14 at 70,156,727 bp
  • A to T, chromosome 15 at 6,486,712 bp
  • G to A, chromosome 15 at 31,273,198 bp
  • T to C, chromosome 15 at 76,344,819 bp
  • T to C, chromosome 15 at 76,723,804 bp
  • T to A, chromosome 15 at 99,199,247 bp
  • T to A, chromosome 16 at 17,130,766 bp
  • T to A, chromosome 16 at 27,409,356 bp
  • C to T, chromosome 16 at 32,256,595 bp
  • A to T, chromosome 17 at 32,671,199 bp
  • G to A, chromosome 17 at 37,466,550 bp
  • A to G, chromosome 17 at 46,164,814 bp
  • A to G, chromosome 18 at 37,725,944 bp
  • T to C, chromosome 18 at 67,392,976 bp
  • T to A, chromosome 19 at 41,584,750 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain GQC Summary
Gene Specific Genotyping:

To request gene-specific and other genotyping services for a strain, please contact the distribution MMRRC Center for more information.

Background Genetic Quality:

The MMRRC has developed a Genetic Quality Control pipeline using the MiniMUGA array to provide additional information to identify and validate genetic backgrounds of MMRRC strains. For more information on whether genetic background data is available, please contact MMRRC_GeneticQC@med.unc.edu. Note: that MiniMUGA genetic background data is not available on all strains, but can be ordered if desired.

Suggested Control Mice
Littermates of all relevant genotypes.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9013 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.


Disclaimer: If MMRRC Strain Genetic Quality Control (GQC; based on MiniMUGA genotyping and analysis) has been completed for this strain, the information might differ from the genetic background information provided by the submitter. MiniMUGA genetic analysis is done on a strain’s tissue samples taken when archived by or ordered from the assigned MMRRC Center.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
068843-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.