Strain Name:
C57BL/6J-MtgxR9105Btlr/Mmmh
Stock Number:
068917-MU
Citation ID:
RRID:MMRRC_068917-MU
Other Names:
R9105 (G1)
Major Collection:

Strain Information

Cdh11
Name: cadherin 11
Synonyms: osteoblast-cadherin, Cad11, OB-cadherin
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 12552
HGNC: HGNC:1750
Homologene: 1361
Slc12a5
Name: solute carrier family 12, member 5
Synonyms: KCC2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 57138
Homologene: 10665
Fgf8
Name: fibroblast growth factor 8
Synonyms: Fgf-8, Aigf
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 14179
HGNC: HGNC:3686
Homologene: 7715
Msantd3
Name: Myb/SANT-like DNA-binding domain containing 3
Synonyms: 2810429P03Rik, 2410046L14Rik, 5730528L13Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 66665
Homologene: 12452
Ctdspl2
Name: CTD small phosphatase like 2
Synonyms: D2Ertd485e, SCP4
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 329506
Homologene: 32311
Pik3c2a
Name: phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha
Synonyms: PI3KC2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18704
HGNC: HGNC:8971
Homologene: 20581
Wdfy3
Name: WD repeat and FYVE domain containing 3
Synonyms: D5Ertd66e, Bwf1, 2610509D04Rik, Bchs, Ggtb3, Alfy
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 72145
Homologene: 22855
Vps13c
Name: vacuolar protein sorting 13C
Synonyms: C230055H22Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 320528
VEGA: 9
Homologene: 41188
Apbb2
Name: amyloid beta precursor protein binding family B member 2
Synonyms: Rirl1, 2310007D03Rik, TR2L, Zfra, FE65L1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 11787
HGNC: HGNC:582
Homologene: 32079
Adgrl2
Name: adhesion G protein-coupled receptor L2
Synonyms: Lphh1, Lec1, Lphn2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99633
Homologene: 22712
Gab1
Name: growth factor receptor bound protein 2-associated protein 1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 14388
HGNC: HGNC:4066
Homologene: 1542
Cep350
Name: centrosomal protein 350
Synonyms: 4933409L06Rik, 6430546F08Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 74081
Homologene: 8879
Ttk
Name: Ttk protein kinase
Synonyms: Esk1, Mps1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 22137
Homologene: 2489
Lypla1
Name: lysophospholipase 1
Synonyms: Gm39587, Pla1a
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 18777
HGNC: HGNC:6737
Homologene: 100781
Ehd4
Name: EH-domain containing 4
Synonyms: 2210022F10Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 98878
HGNC: HGNC:3245
Homologene: 26430
Gtf2b
Name: general transcription factor IIB
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229906
HGNC: HGNC:4648
Homologene: 1158
Tmem131
Name: transmembrane protein 131
Synonyms: CC28, YR-23, D1Bwg0491e, Rw1, Neg, 2610524E03Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 56030
Homologene: 32428
Acsl5
Name: acyl-CoA synthetase long-chain family member 5
Synonyms: 1700030F05Rik, Facl5
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 433256
VEGA: 19
Homologene: 69208
Btnl9
Name: butyrophilin-like 9
Synonyms: D330012D11Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237754
Homologene: 68540
Lrrtm3
Name: leucine rich repeat transmembrane neuronal 3
Synonyms: 9630044H04Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216028
Homologene: 37110
Myo19
Name: myosin XIX
Synonyms: 1110055A02Rik, Myohd1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 66196
Homologene: 49819
Dolpp1
Name: dolichyl pyrophosphate phosphatase 1
Synonyms: 0610011H20Rik, LSFR2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 57170
Homologene: 10663
Efr3b
Name: EFR3 homolog B
Synonyms: C030014M07Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 668212
VEGA: 12
Homologene: 66195
Psmb9
Name: proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)
Synonyms: Lmp2, Lmp-2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 16912
HGNC: HGNC:9546
Homologene: 2094
Col5a2
Name: collagen, type V, alpha 2
Synonyms: 1110014L14Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12832
HGNC: HGNC:2210
Homologene: 20119
Lrp1b
Name: low density lipoprotein-related protein 1B
Synonyms: 9630004P12Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 94217
HGNC: HGNC:6693
Homologene: 56810
Ccdc97
Name: coiled-coil domain containing 97
Synonyms: 1200014H14Rik, 2810446P04Rik, D7Ertd462e
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 52132
Homologene: 32701
Adam34
Name: a disintegrin and metallopeptidase domain 34
Synonyms: testase 4
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 252866
Homologene: 78104
Frmd4a
Name: FERM domain containing 4A
Synonyms: Gm13190, 2700017I06Rik, C230040M21Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 209630
Homologene: 9971
Itgb7
Name: integrin beta 7
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 16421
HGNC: HGNC:6162
Homologene: 20247
Or1j14
Name: olfactory receptor family 1 subfamily J member 14
Synonyms: GA_x6K02T2NLDC-33222024-33222962, MOR136-4, Olfr342
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258950
Homologene: 74223
Ndst2
Name: N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
Synonyms: glucosaminyl N-deacetylase/N-sulphotransferase-2, [Heparan sulfate]-glucosamine N-sulfotransferase, Mndns
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 17423
VEGA: 14
HGNC: HGNC:7681
Homologene: 20803
1700017N19Rik
Name: RIKEN cDNA 1700017N19 gene
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 66605
Homologene: 45135
Bcl3
Name: B cell leukemia/lymphoma 3
Synonyms: Bcl-3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 12051
HGNC: HGNC:998
Homologene: 81738
Ip6k3
Name: inositol hexaphosphate kinase 3
Synonyms: Ihpk3, D830007E07Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 271424
Homologene: 65257
Or6p1
Name: olfactory receptor family 6 subfamily P member 1
Synonyms: Olfr414, MOR103-10, GA_x6K02T2P20D-20749615-20748662
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 258756
Homologene: 17383
Srrd
Name: SRR1 domain containing
Synonyms: 2810002G02Rik, Srr1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 70118
Homologene: 33447
Muc17
Name: mucin 17, cell surface associated
Synonyms: Muc3
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 666339
Homologene: 141159
Pramel14
Name: PRAME like 14
Synonyms: Pramef17, Gm13107
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 626943
Homologene: 129642
Pla2g6
Name: phospholipase A2, group VI
Synonyms: iPLA2, iPLA2beta
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 53357
HGNC: HGNC:9039
Homologene: 2635
Vnn3
Name: vanin 3
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 26464
Homologene: 48295
Gbp9
Name: guanylate-binding protein 9
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 236573
Homologene: 128731
Lca5l
Name: Leber congenital amaurosis 5-like
Synonyms: 4921526F01Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 385668
HGNC: HGNC:1255
Homologene: 47978
Actrt2
Name: actin-related protein T2
Synonyms: 1700052K15Rik, Arp-T2, Arpm2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 73353
Homologene: 23647
Lancl1
Name: LanC (bacterial lantibiotic synthetase component C)-like 1
Synonyms: p40, Gpr69a, LanC-like protein 1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 14768
HGNC: HGNC:6508
Homologene: 4417
Klk15
Name: kallikrein related-peptidase 15
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 317652
Homologene: 77571
Xkr8
Name: X-linked Kx blood group related 8
Synonyms: LOC381560, 4931440N07Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 381560
Homologene: 23068
Gm340
Name: predicted gene 340
Synonyms: LOC381224
Type: Gene
Species: Mouse
Chromosome: 19
Aig1
Name: androgen-induced 1
Synonyms: CGI-103, 1500031O19Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 66253
Homologene: 32297
Calhm5
Name: calcium homeostasis modulator family member 5
Synonyms: Fam26e
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 103511
VEGA: 10
Homologene: 17807
G6pc3
Name: glucose 6 phosphatase, catalytic, 3
Synonyms: 0710001K01Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 68401
Homologene: 16304
Psg17
Name: pregnancy specific beta-1-glycoprotein 17
Synonyms: mmCGM5, Cea-2, Cea2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 26437
HGNC: HGNC:1819
Homologene: 110989
Pnrc1
Name: proline-rich nuclear receptor coactivator 1
Synonyms: B4-2, PRR2, 5730463C12Rik, Prol2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 108767
Homologene: 4960
Apol11b
Name: apolipoprotein L 11b
Synonyms: A330102K04Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 328563
Homologene: 129975
Tcp10b
Name: t-complex protein 10b
Synonyms: Tcp-10bt, D17Leh66ba, Tcp-10b, D17Leh66B, T66B-a
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 21462
Homologene: 83254
Hps4
Name: HPS4, biogenesis of lysosomal organelles complex 3 subunit 2
Synonyms: Hermansky-Pudlak syndrome 4, BLOC-3, C130020P05Rik, 2010205O06Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 192232
Homologene: 11123
Btbd19
Name: BTB domain containing 19
Synonyms: 9530048O09Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 78611
Or4c117
Name: olfactory receptor family 4 subfamily C member 117
Synonyms: MOR233-14, Olfr1222, GA_x6K02T2Q125-50604368-50603433
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258177
Homologene: 73988
Or12d16-ps1
Name: olfactory receptor family 12 subfamily D member 16, pseudogene 1
Synonyms: Olfr106, MOR250-6, Olfr106-ps, GA_x6K02T2PSCP-1855511-1856437
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 257925
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 4,841,059 bp
  • C to A, chromosome 1 at 36,815,510 bp
  • T to A, chromosome 1 at 45,380,206 bp
  • T to A, chromosome 1 at 67,004,803 bp
  • T to C, chromosome 1 at 155,959,815 bp
  • T to A, chromosome 1 at 174,431,295 bp
  • A to G, chromosome 2 at 4,535,183 bp
  • A to T, chromosome 2 at 30,399,140 bp
  • A to G, chromosome 2 at 36,528,282 bp
  • A to G, chromosome 2 at 41,506,791 bp
  • C to T, chromosome 2 at 89,125,651 bp
  • T to C, chromosome 2 at 120,102,279 bp
  • C to T, chromosome 2 at 122,006,870 bp
  • A to G, chromosome 2 at 164,996,194 bp
  • T to A, chromosome 3 at 142,783,289 bp
  • T to C, chromosome 3 at 148,837,653 bp
  • C to A, chromosome 4 at 33,246,207 bp
  • A to T, chromosome 4 at 48,560,963 bp
  • C to T, chromosome 4 at 117,120,764 bp
  • A to T, chromosome 4 at 132,732,337 bp
  • A to T, chromosome 4 at 143,992,025 bp
  • G to A, chromosome 4 at 154,667,220 bp
  • G to T, chromosome 5 at 66,302,672 bp
  • T to C, chromosome 5 at 101,882,646 bp
  • A to G, chromosome 5 at 105,094,076 bp
  • T to C, chromosome 5 at 112,337,599 bp
  • G to A, chromosome 5 at 112,378,039 bp
  • T to C, chromosome 5 at 137,142,390 bp
  • A to T, chromosome 7 at 18,821,408 bp
  • T to A, chromosome 7 at 19,809,250 bp
  • T to C, chromosome 7 at 25,713,112 bp
  • C to T, chromosome 7 at 43,938,366 bp
  • T to C, chromosome 7 at 116,372,814 bp
  • C to T, chromosome 8 at 43,650,748 bp
  • T to C, chromosome 8 at 80,788,960 bp
  • T to C, chromosome 8 at 102,634,336 bp
  • T to G, chromosome 9 at 67,870,799 bp
  • T to A, chromosome 9 at 83,863,491 bp
  • T to C, chromosome 10 at 13,653,595 bp
  • T to C, chromosome 10 at 23,864,563 bp
  • A to G, chromosome 10 at 34,092,148 bp
  • A to G, chromosome 10 at 64,088,557 bp
  • A to T, chromosome 10 at 100,603,545 bp
  • G to A, chromosome 11 at 49,175,634 bp
  • T to C, chromosome 11 at 84,903,203 bp
  • C to T, chromosome 11 at 102,193,577 bp
  • A to T, chromosome 12 at 3,981,782 bp
  • T to C, chromosome 14 at 20,730,002 bp
  • C to T, chromosome 15 at 77,640,571 bp
  • T to A, chromosome 15 at 79,299,197 bp
  • A to G, chromosome 15 at 102,227,469 bp
  • T to G, chromosome 16 at 96,159,471 bp
  • T to C, chromosome 17 at 13,066,349 bp
  • A to G, chromosome 17 at 27,145,195 bp
  • A to T, chromosome 17 at 34,182,931 bp
  • C to T, chromosome 17 at 37,394,840 bp
  • G to A, chromosome 19 at 41,584,872 bp
  • A to C, chromosome 19 at 45,742,051 bp
  • A to T, chromosome 19 at 55,280,570 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9105 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
068917-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.