Strain Name:
C57BL/6J-MtgxR9109Btlr/Mmmh
Stock Number:
068918-MU
Citation ID:
RRID:MMRRC_068918-MU
Other Names:
R9109 (G1)
Major Collection:

Strain Information

Kdm5b
Name: lysine demethylase 5B
Synonyms: Rb-Bp2, 2210016I17Rik, Jarid1b, 2010009J12Rik, D1Ertd202e, Plu1, PLU-1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 75605
Homologene: 48448
Col18a1
Name: collagen, type XVIII, alpha 1
Synonyms: endostatin
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 12822
HGNC: HGNC:2195
Homologene: 7673
Pecam1
Name: platelet/endothelial cell adhesion molecule 1
Synonyms: PECAM-1, Cd31
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18613
HGNC: HGNC:8823
Homologene: 47925
Etv4
Name: ets variant 4
Synonyms: Pea-3, Pea3
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18612
HGNC: HGNC:3493
Homologene: 1504
Apbb2
Name: amyloid beta precursor protein binding family B member 2
Synonyms: Rirl1, 2310007D03Rik, TR2L, Zfra, FE65L1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 11787
HGNC: HGNC:582
Homologene: 32079
Btaf1
Name: B-TFIID TATA-box binding protein associated factor 1
Synonyms: E430027O22Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 107182
Homologene: 31978
Rnps1
Name: RNA binding protein with serine rich domain 1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 19826
VEGA: 17
Homologene: 40648
Cenpf
Name: centromere protein F
Synonyms: mitosin, Lek1, 6530404A22Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 108000
HGNC: HGNC:1857
Homologene: 22969
Lpin2
Name: lipin 2
Synonyms: 2610511G02Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 64898
Homologene: 8769
Arid4a
Name: AT-rich interaction domain 4A
Synonyms: A630067N03Rik, Rbbp1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238247
HGNC: HGNC:9885
Homologene: 11303
Sox8
Name: SRY (sex determining region Y)-box 8
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 20681
Homologene: 7950
Atp13a3
Name: ATPase type 13A3
Synonyms: LOC224087, LOC224088, LOC385637
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224088
Homologene: 23455
Syt14
Name: synaptotagmin XIV
Synonyms: B230320I09Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 329324
Homologene: 17719
Tle3
Name: transducin-like enhancer of split 3
Synonyms: Grg3b, ESG, Grg3a, 2610103N05Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 21887
Homologene: 21059
Flrt3
Name: fibronectin leucine rich transmembrane protein 3
Synonyms: 5530600M07Rik, C430047I10Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 71436
HGNC: HGNC:3762
Homologene: 8322
Synrg
Name: synergin, gamma
Synonyms: L71-5, Ap1gbp1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217030
HGNC: HGNC:557
Homologene: 105680
Fam219a
Name: family with sequence similarity 219, member A
Synonyms: 2310028H24Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 71901
Homologene: 51830
Dnhd1
Name: dynein heavy chain domain 1
Synonyms: 8030491N06Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 77505
Homologene: 131117
Zglp1
Name: zinc finger, GATA-like protein 1
Synonyms: Glp1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 100009600
VEGA: 9
Homologene: 104472
Col1a2
Name: collagen, type I, alpha 2
Synonyms: Cola2, Cola-2, Col1a-2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 12843
HGNC: HGNC:2198
Homologene: 69
Dusp19
Name: dual specificity phosphatase 19
Synonyms: 5930436K22Rik, SKRP1, C79103, TS-DSP1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 68082
Homologene: 41565
Siglecl2
Name: Siglec family like 2
Synonyms: 4931406B18Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 74054
Homologene: 105741
Wdfy4
Name: WD repeat and FYVE domain containing 4
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 545030
Homologene: 83473
Kif5c
Name: kinesin family member 5C
Synonyms: Khc
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 16574
HGNC: HGNC:6325
Homologene: 56234
Specc1
Name: sperm antigen with calponin homology and coiled-coil domains 1
Synonyms: Cytsb, 2810012G08Rik, B230396K10Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 432572
Homologene: 45157
Csmd3
Name: CUB and Sushi multiple domains 3
Synonyms: 4930500N14Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 239420
Homologene: 65982
Slc7a6
Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 6
Synonyms: LAT-2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 330836
Homologene: 62496
4930407I10Rik
Name: RIKEN cDNA 4930407I10 gene
Synonyms: LOC328573
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 328573
VEGA: 15
Homologene: 130065
Vmn2r5
Name: vomeronasal 2, receptor 5
Synonyms: EG667060
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 667060
Unc13a
Name: unc-13 homolog A
Synonyms: Munc13-1, 2410078G03Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 382018
Homologene: 11279
S100pbp
Name: S100P binding protein
Synonyms: 4930429A08Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 74648
Homologene: 81892
Sobp
Name: sine oculis binding protein
Synonyms: 5330439J01Rik, jc, Jxc1, 2900009C16Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 109205
Homologene: 41216
Cmklr1
Name: chemerin chemokine-like receptor 1
Synonyms: ChemR23, Gpcr27
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 14747
HGNC: HGNC:2121
Homologene: 129967
Brf1
Name: BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
Synonyms: 2510002F24Rik, GTF3B, TAF3C, TFIIIB90, TAFIII90
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 72308
VEGA: 12
Homologene: 1161
Vmn2r27
Name: vomeronasal 2, receptor27
Synonyms: EG232367
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232367
Fau
Name: FAU ubiquitin like and ribosomal protein S30 fusion
Synonyms: MNSFbeta, MNSFB, Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived), monoclonal nonspecific suppressor factor beta
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 14109
VEGA: 19
HGNC: HGNC:3597
Homologene: 37562
Igfn1
Name: immunoglobulin-like and fibronectin type III domain containing 1
Synonyms: 9830123M21Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226438
Homologene: 130054
Vmn2r91
Name: vomeronasal 2, receptor 91
Synonyms: EG665210
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 665210
Homologene: 115024
Ptpre
Name: protein tyrosine phosphatase receptor type E
Synonyms: RPTPepsilon, PTPe, PTPepsilon
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 19267
HGNC: HGNC:9669
Homologene: 31387
Sema5a
Name: sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
Synonyms: 9130201M22Rik, semF, M-Sema D, Semaf
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 20356
VEGA: 15
Homologene: 2949
Kcnt2
Name: potassium channel, subfamily T, member 2
Synonyms: E330038N15Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 240776
Homologene: 16121
Svop
Name: SV2 related protein
Synonyms: msvop, 1110030H18Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 68666
Homologene: 41283
Slc66a2
Name: solute carrier family 66 member 2
Synonyms: C78974, 4933425L21Rik, 5730564E11Rik, 2310009N05Rik, Pqlc1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 66943
Homologene: 32623
Cyp4a29
Name: cytochrome P450, family 4, subfamily a, polypeptide 29
Synonyms: Cyp4a29-ps
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230639
Pigc
Name: phosphatidylinositol glycan anchor biosynthesis, class C
Synonyms: 3110030E07Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 67292
HGNC: HGNC:8960
Homologene: 7109
Zfp709
Name: zinc finger protein 709
Synonyms: GIOT-4
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 236193
Homologene: 136795
Nox4
Name: NADPH oxidase 4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 50490
HGNC: HGNC:7891
Homologene: 41065
Tcp11l1
Name: t-complex 11 like 1
Synonyms: C130096D04Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 320554
Homologene: 41260
1700030K09Rik
Name: RIKEN cDNA 1700030K09 gene
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 72254
Homologene: 12975
Or10a5
Name: olfactory receptor family 10 subfamily A member 5
Synonyms: MOR263-1, P3, Olfr713, GA_x6K02T2PBJ9-9415724-9416677
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259036
Homologene: 17470
Gm4353
Name: predicted gene 4353
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 100043313
VEGA: 7
Mettl22
Name: methyltransferase 22, Kin17 lysine
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 239706
Homologene: 16619
Or5k8
Name: olfactory receptor family 5 subfamily K member 8
Synonyms: Olfr174, GA_x54KRFPKG5P-55026345-55025418, GA_x54KRFPKG5P-54993816-54992890, MOR184-1, Olfr175-ps1, MOR184-10P, Olfr175
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 259004
Homologene: 17461
Pih1d1
Name: PIH1 domain containing 1
Synonyms: 1110061L23Rik, 4933413A04Rik, Nop17
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 68845
Homologene: 9914
Slc38a8
Name: solute carrier family 38, member 8
Synonyms: LOC234788
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234788
Homologene: 19028
Jakmip3
Name: janus kinase and microtubule interacting protein 3
Synonyms: 6330417G02Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 74004
Homologene: 90425
Slc4a1ap
Name: solute carrier family 4 (anion exchanger), member 1, adaptor protein
Synonyms: kanadaptin
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 20534
Homologene: 7543
Kctd14
Name: potassium channel tetramerisation domain containing 14
Synonyms: AI449310, D7Ertd760e
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233529
Homologene: 11396
Or5b95
Name: olfactory receptor family 5 subfamily B member 95
Synonyms: Olfr1443, GA_x6K02T2RE5P-3006492-3007430, MOR202-8
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258693
HGNC: HGNC:8324
Homologene: 115496
Tcp10c
Name: t-complex protein 10c
Synonyms: Gm9880, Tcp-10c, D17Leh66C, D17Leh66ca, T66C-a
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 100041352
VEGA: 17
Homologene: 83254
Tex51
Name: testis expressed 51
Synonyms: Gm35060
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 102638514
Homologene: 132337
Cdhr17
Name: cadherin related family member 17
Synonyms: Gm28710
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 102640594
Homologene: 141132
Exosc6
Name: exosome component 6
Synonyms: 2610510N21Rik, Mtr3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 72544
Homologene: 12469
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 134,600,755 bp
  • A to G, chromosome 1 at 135,998,589 bp
  • T to A, chromosome 1 at 140,425,297 bp
  • C to T, chromosome 1 at 161,970,463 bp
  • T to C, chromosome 1 at 189,659,374 bp
  • C to A, chromosome 1 at 192,930,636 bp
  • A to G, chromosome 2 at 49,730,139 bp
  • T to C, chromosome 2 at 80,617,385 bp
  • C to T, chromosome 2 at 104,698,552 bp
  • T to C, chromosome 2 at 140,659,959 bp
  • A to T, chromosome 2 at 175,170,076 bp
  • T to G, chromosome 3 at 64,503,990 bp
  • G to A, chromosome 4 at 41,521,870 bp
  • T to A, chromosome 4 at 115,251,198 bp
  • A to G, chromosome 4 at 129,151,054 bp
  • T to A, chromosome 5 at 16,792,911 bp
  • T to C, chromosome 5 at 31,536,194 bp
  • T to C, chromosome 5 at 66,451,675 bp
  • G to C, chromosome 5 at 113,613,982 bp
  • G to A, chromosome 5 at 114,030,170 bp
  • T to A, chromosome 6 at 4,515,260 bp
  • T to C, chromosome 6 at 124,197,265 bp
  • C to A, chromosome 7 at 43,499,278 bp
  • T to C, chromosome 7 at 45,159,769 bp
  • G to A, chromosome 7 at 87,376,240 bp
  • A to G, chromosome 7 at 97,458,036 bp
  • A to G, chromosome 7 at 105,683,966 bp
  • A to T, chromosome 7 at 107,036,433 bp
  • T to A, chromosome 7 at 116,083,608 bp
  • A to G, chromosome 7 at 135,669,779 bp
  • A to T, chromosome 7 at 139,020,831 bp
  • C to T, chromosome 8 at 71,655,691 bp
  • A to T, chromosome 8 at 71,890,804 bp
  • C to A, chromosome 8 at 72,445,079 bp
  • T to C, chromosome 8 at 106,195,902 bp
  • G to A, chromosome 8 at 111,056,881 bp
  • A to G, chromosome 8 at 119,486,112 bp
  • A to T, chromosome 9 at 21,066,186 bp
  • T to A, chromosome 9 at 61,412,280 bp
  • A to T, chromosome 10 at 43,022,906 bp
  • G to A, chromosome 10 at 77,057,370 bp
  • A to G, chromosome 11 at 62,211,638 bp
  • A to G, chromosome 11 at 84,009,452 bp
  • A to G, chromosome 11 at 101,773,666 bp
  • G to T, chromosome 11 at 106,695,761 bp
  • C to A, chromosome 12 at 71,075,355 bp
  • A to G, chromosome 12 at 112,963,391 bp
  • A to T, chromosome 14 at 33,038,747 bp
  • A to G, chromosome 15 at 32,618,894 bp
  • A to C, chromosome 15 at 47,753,791 bp
  • A to G, chromosome 15 at 82,063,414 bp
  • G to A, chromosome 16 at 8,487,367 bp
  • A to G, chromosome 16 at 30,315,898 bp
  • A to T, chromosome 16 at 58,824,314 bp
  • A to T, chromosome 17 at 13,356,388 bp
  • A to G, chromosome 17 at 18,107,643 bp
  • A to G, chromosome 17 at 24,418,599 bp
  • T to C, chromosome 17 at 25,568,839 bp
  • T to C, chromosome 17 at 71,231,521 bp
  • T to C, chromosome 18 at 32,460,976 bp
  • T to C, chromosome 18 at 80,257,085 bp
  • G to A, chromosome 19 at 6,058,267 bp
  • T to A, chromosome 19 at 12,680,826 bp
  • A to G, chromosome 19 at 36,986,714 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9109 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
068918-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.