Loading Mouse GIF
Loading...

Strain Name:
C57BL/6J-MtgxR9039Btlr/Mmmh
Stock Number:
068993-MU
Citation ID:
RRID:MMRRC_068993-MU
Other Names:
R9039 (G1)
Major Collection:

Strain Information

Neurod1
Name: neurogenic differentiation 1
Synonyms: BETA2, Neurod, bHLHa3, Nd1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 18012
HGNC: HGNC:7762
Homologene: 1871
Prkd3
Name: protein kinase D3
Synonyms: 4930557O20Rik, 5730497N19Rik, PKD3, Prkcn
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 75292
HGNC: HGNC:9408
Homologene: 2055
Adcy10
Name: adenylate cyclase 10
Synonyms: soluble adenylyl cyclase, sAC, 4930431D04Rik, Sacy
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 271639
Homologene: 10188
Lars1
Name: leucyl-tRNA synthetase 1
Synonyms: 3110009L02Rik, 2310045K21Rik, Lars
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 107045
VEGA: 18
HGNC: HGNC:6512
Homologene: 7083
Trmo
Name: tRNA methyltransferase O
Synonyms: 5830415F09Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 74753
Homologene: 32316
Ppp1r9a
Name: protein phosphatase 1, regulatory subunit 9A
Synonyms: 4930518N04Rik, neurabin-I, A230094E16Rik, 2810430P21Rik, Neurabin I, NRB
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243725
Homologene: 14247
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to A, chromosome 1 at 135,443,749 bp (GRCm38)
  • T to C, chromosome 1 at 136,088,319 bp (GRCm38)
  • A to T, chromosome 1 at 161,251,049 bp (GRCm38)
  • T to C, chromosome 1 at 165,518,345 bp (GRCm38)
  • A to G, chromosome 1 at 182,854,032 bp (GRCm38)
  • T to A, chromosome 2 at 31,354,634 bp (GRCm38)
  • T to A, chromosome 2 at 72,482,512 bp (GRCm38)
  • T to C, chromosome 2 at 79,454,376 bp (GRCm38)
  • C to A, chromosome 2 at 82,998,201 bp (GRCm38)
  • T to C, chromosome 2 at 86,146,281 bp (GRCm38)
  • T to C, chromosome 2 at 87,903,563 bp (GRCm38)
  • G to T, chromosome 2 at 89,249,201 bp (GRCm38)
  • C to T, chromosome 2 at 90,815,386 bp (GRCm38)
  • G to T, chromosome 2 at 162,966,068 bp (GRCm38)
  • A to T, chromosome 3 at 37,232,453 bp (GRCm38)
  • A to G, chromosome 3 at 93,203,592 bp (GRCm38)
  • A to G, chromosome 3 at 103,912,235 bp (GRCm38)
  • A to G, chromosome 3 at 127,679,543 bp (GRCm38)
  • A to T, chromosome 4 at 12,980,490 bp (GRCm38)
  • A to T, chromosome 4 at 19,540,770 bp (GRCm38)
  • T to C, chromosome 4 at 46,382,322 bp (GRCm38)
  • A to G, chromosome 4 at 63,356,296 bp (GRCm38)
  • C to T, chromosome 4 at 104,822,003 bp (GRCm38)
  • A to T, chromosome 4 at 115,487,264 bp (GRCm38)
  • T to C, chromosome 4 at 117,900,988 bp (GRCm38)
  • C to A, chromosome 4 at 134,195,547 bp (GRCm38)
  • T to A, chromosome 5 at 92,272,441 bp (GRCm38)
  • G to C, chromosome 5 at 108,705,573 bp (GRCm38)
  • A to T, chromosome 5 at 109,220,036 bp (GRCm38)
  • C to T, chromosome 5 at 110,204,933 bp (GRCm38)
  • A to G, chromosome 6 at 5,134,657 bp (GRCm38)
  • G to A, chromosome 6 at 14,754,526 bp (GRCm38)
  • A to T, chromosome 6 at 42,817,611 bp (GRCm38)
  • A to G, chromosome 6 at 47,551,737 bp (GRCm38)
  • A to G, chromosome 6 at 56,956,837 bp (GRCm38)
  • G to T, chromosome 7 at 12,971,528 bp (GRCm38)
  • A to C, chromosome 7 at 27,250,586 bp (GRCm38)
  • A to T, chromosome 7 at 45,034,722 bp (GRCm38)
  • A to T, chromosome 7 at 105,756,008 bp (GRCm38)
  • C to A, chromosome 9 at 7,581,249 bp (GRCm38)
  • A to G, chromosome 9 at 37,237,362 bp (GRCm38)
  • A to G, chromosome 9 at 45,945,350 bp (GRCm38)
  • A to G, chromosome 9 at 86,500,817 bp (GRCm38)
  • G to T, chromosome 9 at 108,804,608 bp (GRCm38)
  • T to A, chromosome 10 at 24,279,353 bp (GRCm38)
  • T to A, chromosome 10 at 39,135,021 bp (GRCm38)
  • T to C, chromosome 10 at 76,327,719 bp (GRCm38)
  • C to T, chromosome 10 at 82,867,731 bp (GRCm38)
  • A to G, chromosome 10 at 128,083,898 bp (GRCm38)
  • G to A, chromosome 11 at 63,081,343 bp (GRCm38)
  • A to G, chromosome 11 at 91,576,305 bp (GRCm38)
  • T to G, chromosome 12 at 8,744,430 bp (GRCm38)
  • T to C, chromosome 12 at 71,167,075 bp (GRCm38)
  • T to C, chromosome 13 at 41,318,508 bp (GRCm38)
  • C to T, chromosome 13 at 54,796,178 bp (GRCm38)
  • C to T, chromosome 13 at 96,543,209 bp (GRCm38)
  • G to T, chromosome 14 at 26,533,364 bp (GRCm38)
  • T to A, chromosome 14 at 122,126,164 bp (GRCm38)
  • G to T, chromosome 15 at 47,619,912 bp (GRCm38)
  • C to A, chromosome 15 at 75,045,451 bp (GRCm38)
  • C to G, chromosome 15 at 81,872,419 bp (GRCm38)
  • A to T, chromosome 16 at 91,906,770 bp (GRCm38)
  • A to G, chromosome 17 at 24,607,515 bp (GRCm38)
  • A to T, chromosome 17 at 78,972,574 bp (GRCm38)
  • T to A, chromosome 18 at 12,481,063 bp (GRCm38)
  • T to C, chromosome 18 at 42,257,169 bp (GRCm38)
  • A to G, chromosome 19 at 10,596,248 bp (GRCm38)
  • G to T, chromosome 19 at 15,959,543 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain GQC Summary
Gene Specific Genotyping:

To request gene-specific and other genotyping services for a strain, please contact the distribution MMRRC Center for more information.

Background Genetic Quality:

The MMRRC has developed a Genetic Quality Control pipeline using the MiniMUGA array to provide additional information to identify and validate genetic backgrounds of MMRRC strains. For more information on whether genetic background data is available, please contact MMRRC_GeneticQC@med.unc.edu. Note: that MiniMUGA genetic background data is not available on all strains, but can be ordered if desired.

Suggested Control Mice
Littermates of all relevant genotypes.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9039 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.


Disclaimer: If MMRRC Strain Genetic Quality Control (GQC; based on MiniMUGA genotyping and analysis) has been completed for this strain, the information might differ from the genetic background information provided by the submitter. MiniMUGA genetic analysis is done on a strain’s tissue samples taken when archived by or ordered from the assigned MMRRC Center.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
068993-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.