Strain Name:
C57BL/6J-MtgxR9112Btlr/Mmmh
Stock Number:
069002-MU
Citation ID:
RRID:MMRRC_069002-MU
Other Names:
R9112 (G1)
Major Collection:

Strain Information

Pcp2
Name: Purkinje cell protein 2 (L7)
Synonyms: L7, Pcp-2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 18545
Homologene: 7464
Dhrs3
Name: dehydrogenase/reductase 3
Synonyms: retSDR1, Rsdr1, dehydrogenase/reductase (SDR family) member 3
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 20148
Homologene: 20994
Myo1e
Name: myosin IE
Synonyms: 2310020N23Rik, 9130023P14Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 71602
VEGA: 9
HGNC: HGNC:7599
Homologene: 55864
Pigv
Name: phosphatidylinositol glycan anchor biosynthesis, class V
Synonyms: D430024F16Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230801
Homologene: 5354
Ube2e1
Name: ubiquitin-conjugating enzyme E2E 1
Synonyms: ubcM2, UbcM3, Ubce5
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 22194
Homologene: 84372
Dip2c
Name: disco interacting protein 2 homolog C
Synonyms: 2900024P20Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 208440
Homologene: 40996
Eprs1
Name: glutamyl-prolyl-tRNA synthetase 1
Synonyms: Qprs, 3010002K18Rik, 2410081F06Rik, Eprs
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 107508
HGNC: HGNC:3418
Homologene: 5870
Agrn
Name: agrin
Synonyms: NMF380, Agrin, nmf380
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 11603
HGNC: HGNC:329
Homologene: 27907
Kat6b
Name: K(lysine) acetyltransferase 6B
Synonyms: qkf, querkopf, Morf, B130044K16Rik, monocytic leukemia, Myst4
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 54169
Homologene: 136480
Rufy3
Name: RUN and FYVE domain containing 3
Synonyms: 2810428M05Rik, 6330416M07Rik, D5Bwg0860e, Rpipx
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 52822
Homologene: 87809
Gnai3
Name: G protein subunit alpha i3
Synonyms: Galphai3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 14679
HGNC: HGNC:4387
Homologene: 55975
Arhgap32
Name: Rho GTPase activating protein 32
Synonyms: GC-GAP, p200RhoGAP, PX-RICS, 3426406O18Rik, Grit
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 330914
Homologene: 8812
Trappc10
Name: trafficking protein particle complex 10
Synonyms: LOC380642, B230307C21Rik, Tmem1, b2b2613Clo, b2b2416Clo
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216131
VEGA: 10
Homologene: 37751
Acy1
Name: aminoacylase 1
Synonyms: Acy-1, 1110014J22Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 109652
HGNC: HGNC:177
Homologene: 110440
Ift74
Name: intraflagellar transport 74
Synonyms: 1700029H06Rik, Cmg1, Ccdc2, b2b796Clo
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 67694
Homologene: 11831
Apobec1
Name: apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 11810
HGNC: HGNC:604
Homologene: 1243
Golga3
Name: golgin A3
Synonyms: Mea-2, Mea2, 5430416E01Rik, G1-499-14, repro27
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 269682
HGNC: HGNC:4426
Homologene: 4308
Gpc6
Name: glypican 6
Synonyms: 6720429C22Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 23888
HGNC: HGNC:4454
Homologene: 55922
Adgra3
Name: adhesion G protein-coupled receptor A3
Synonyms: 3830613O22Rik, Tem5-like, Gpr125
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 70693
Homologene: 19235
Lrrc8a
Name: leucine rich repeat containing 8A VRAC subunit A
Synonyms: Lrrc8, ebo, SWELL1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241296
Homologene: 18617
Map2
Name: microtubule-associated protein 2
Synonyms: MAP-2, G1-397-34, Mtap2, repro4
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 17756
HGNC: HGNC:6839
Homologene: 1779
Synrg
Name: synergin, gamma
Synonyms: L71-5, Ap1gbp1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217030
HGNC: HGNC:557
Homologene: 105680
Slc38a9
Name: solute carrier family 38, member 9
Synonyms: 9430067K09Rik, 6720411P22Rik, 9130023D20Rik, 4833412L08Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 268706
VEGA: 13
Homologene: 18139
Fam13c
Name: family with sequence similarity 13, member C
Synonyms: C030038O19Rik, 1200015N20Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 71721
Homologene: 11490
Tdrp
Name: testis development related protein
Synonyms: 2610019F03Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 72148
Homologene: 18348
Adamts13
Name: ADAM metallopeptidase with thrombospondin type 1 motif 13
Synonyms: LOC279028, vWF-CP mRNA for von Willebrand factor-cleaving
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 279028
HGNC: HGNC:1366
Homologene: 16372
Bcat2
Name: branched chain aminotransferase 2, mitochondrial
Synonyms: Eca40, Bcat-2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 12036
HGNC: HGNC:977
Homologene: 81684
Afp
Name: alpha fetoprotein
Synonyms: alpha-foetoprotein
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 11576
HGNC: HGNC:317
Homologene: 36278
Ahnak
Name: AHNAK nucleoprotein
Synonyms: DY6, 2310047C17Rik, 1110004P15Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 66395
VEGA: 19
HGNC: HGNC:347
Homologene: 67425
Cyp2d11
Name: cytochrome P450, family 2, subfamily d, polypeptide 11
Synonyms: P450-2D, Cyp2d
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 545123
VEGA: 15
Homologene: 86099
Vwde
Name: von Willebrand factor D and EGF domains
Synonyms: LOC232585
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232585
Homologene: 35456
Or4a71
Name: olfactory receptor family 4 subfamily A member 71
Synonyms: GA_x6K02T2Q125-50972538-50971621, MOR231-4, Olfr1243
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258971
Homologene: 27317
Plekhh3
Name: pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217198
Homologene: 11787
Or9q2
Name: olfactory receptor family 9 subfamily Q member 2
Synonyms: GA_x6K02T2RE5P-4127765-4126821, MOR212-1, Olfr1497
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258736
Homologene: 17373
Rhof
Name: ras homolog family member F (in filopodia)
Synonyms: Ifld1, Arhf
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 23912
Homologene: 41304
Sgsm2
Name: small G protein signaling modulator 2
Synonyms: D630003G22Rik, Rutbc1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 97761
Homologene: 14780
Herc6
Name: hect domain and RLD 6
Synonyms: 4930427L17Rik, 1700121D12Rik, CEB1, 2510038N07Rik, Herc5
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 67138
Homologene: 70768
5730596B20Rik
Name: RIKEN cDNA 5730596B20 gene
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 77580
VEGA: 6
Zfyve16
Name: zinc finger, FYVE domain containing 16
Synonyms: B130024H06Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218441
Homologene: 8826
Flt4
Name: FMS-like tyrosine kinase 4
Synonyms: VEGFR3, VEGFR-3, Flt-4
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 14257
HGNC: HGNC:3767
Homologene: 7321
Ap1m1
Name: adaptor-related protein complex AP-1, mu subunit 1
Synonyms: AP47, mu1A, [m]1A, Adtm1A, Cltnm
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 11767
Homologene: 4017
Slc18b1
Name: solute carrier family 18, subfamily B, member 1
Synonyms: 1110021L09Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 76306
Homologene: 33473
Or6ae1
Name: olfactory receptor family 6 subfamily AE member 1
Synonyms: GA_x6K02T2PBJ9-42315125-42314187, MOR103-5, Olfr522
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258954
Homologene: 62435
Cd209f
Name: CD209f antigen
Synonyms: SIGNR8, 1810029C22Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 69142
Homologene: 114519
Nras
Name: neuroblastoma ras oncogene
Synonyms: N-ras
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 18176
HGNC: HGNC:7989
Homologene: 55661
Or5b3
Name: olfactory receptor family 5 subfamily B member 3
Synonyms: GA_x6K02T2RE5P-3743369-3744289, MOR202-11, Olfr1469
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258690
HGNC: HGNC:8324
Homologene: 133675
Garin2
Name: golgi associated RAB2 interactor 2
Synonyms: 4930516C23Rik, 4921509E07Rik, Fam71d
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 70897
Homologene: 49887
Klrh1
Name: killer cell lectin-like receptor subfamily H, member 1
Synonyms: LOC232415, Gm156
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232415
Homologene: 16395
Mrgprf
Name: MAS-related GPR, member F
Synonyms: MrgF
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 211577
Homologene: 17023
Klhl3
Name: kelch-like 3
Synonyms: 7530408C15Rik, EG627648
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 100503085
HGNC: HGNC:6354
Homologene: 79542
Poglut3
Name: protein O-glucosyltransferase 3
Synonyms: 4833410J10Rik, 2010004J24Rik, Kdelc2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 68304
VEGA: 9
Homologene: 17805
Gimap4
Name: GTPase, IMAP family member 4
Synonyms: E430007K16Rik, Ian1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 107526
Homologene: 75084
Cox7c
Name: cytochrome c oxidase subunit 7C
Synonyms: COXVIIc, Cox7c1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 12867
HGNC: HGNC:2292
Homologene: 81691
Lipi
Name: lipase, member I
Synonyms: D930038D03Rik, lpd1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 320355
Homologene: 77864
2310033P09Rik
Name: RIKEN cDNA 2310033P09 gene
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 67862
Homologene: 134536
Serpina1b
Name: serine (or cysteine) preptidase inhibitor, clade A, member 1B
Synonyms: PI2, D12Ucla2, Spi1-2
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 20701
HGNC: HGNC:8941
Homologene: 20103
Pramel51
Name: PRAME like 51
Synonyms: Gm10436
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 100039315
VEGA: 12
Homologene: 103830
Gm5916
Name: predicted gene 5916
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 546123
Gm32742
Name: predicted gene, 32742
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 102635385
Homologene: 132734
H2bc6
Name: H2B clustered histone 6
Synonyms: Hist1h2be
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 319179
Homologene: 136358
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to A, chromosome 1 at 66,433,564 bp (GRCm38)
  • A to T, chromosome 1 at 185,397,076 bp (GRCm38)
  • T to C, chromosome 2 at 26,990,367 bp (GRCm38)
  • T to A, chromosome 2 at 30,255,770 bp (GRCm38)
  • C to T, chromosome 2 at 89,527,993 bp (GRCm38)
  • A to T, chromosome 3 at 103,060,342 bp (GRCm38)
  • A to T, chromosome 3 at 108,123,674 bp (GRCm38)
  • T to C, chromosome 4 at 94,686,866 bp (GRCm38)
  • T to C, chromosome 4 at 133,664,768 bp (GRCm38)
  • A to C, chromosome 4 at 143,896,764 bp (GRCm38)
  • A to T, chromosome 4 at 144,927,199 bp (GRCm38)
  • A to T, chromosome 4 at 156,177,057 bp (GRCm38)
  • C to A, chromosome 5 at 49,961,053 bp (GRCm38)
  • A to T, chromosome 5 at 88,632,477 bp (GRCm38)
  • T to C, chromosome 5 at 90,504,430 bp (GRCm38)
  • G to T, chromosome 5 at 110,185,891 bp (GRCm38)
  • T to C, chromosome 5 at 123,120,508 bp (GRCm38)
  • C to A, chromosome 6 at 13,205,052 bp (GRCm38)
  • T to A, chromosome 6 at 48,690,695 bp (GRCm38)
  • A to G, chromosome 6 at 52,179,433 bp (GRCm38)
  • T to C, chromosome 6 at 57,619,619 bp (GRCm38)
  • T to A, chromosome 6 at 122,578,878 bp (GRCm38)
  • T to A, chromosome 6 at 129,766,734 bp (GRCm38)
  • T to C, chromosome 7 at 45,588,022 bp (GRCm38)
  • A to G, chromosome 7 at 140,162,747 bp (GRCm38)
  • A to G, chromosome 7 at 145,307,766 bp (GRCm38)
  • T to A, chromosome 8 at 3,624,638 bp (GRCm38)
  • T to A, chromosome 8 at 4,105,802 bp (GRCm38)
  • T to C, chromosome 8 at 13,955,796 bp (GRCm38)
  • C to A, chromosome 8 at 72,240,222 bp (GRCm38)
  • G to A, chromosome 9 at 32,246,013 bp (GRCm38)
  • A to G, chromosome 9 at 36,120,962 bp (GRCm38)
  • A to G, chromosome 9 at 51,149,435 bp (GRCm38)
  • A to G, chromosome 9 at 53,384,230 bp (GRCm38)
  • G to T, chromosome 9 at 70,367,701 bp (GRCm38)
  • A to G, chromosome 9 at 106,434,753 bp (GRCm38)
  • A to T, chromosome 10 at 23,816,364 bp (GRCm38)
  • A to G, chromosome 10 at 70,451,148 bp (GRCm38)
  • A to C, chromosome 10 at 78,193,367 bp (GRCm38)
  • A to G, chromosome 11 at 49,633,237 bp (GRCm38)
  • A to G, chromosome 11 at 59,209,980 bp (GRCm38)
  • G to A, chromosome 11 at 74,865,396 bp (GRCm38)
  • C to G, chromosome 11 at 83,971,583 bp (GRCm38)
  • T to A, chromosome 11 at 101,170,799 bp (GRCm38)
  • T to C, chromosome 12 at 78,710,428 bp (GRCm38)
  • C to T, chromosome 12 at 88,177,285 bp (GRCm38)
  • T to C, chromosome 12 at 103,732,440 bp (GRCm38)
  • T to C, chromosome 13 at 9,610,730 bp (GRCm38)
  • T to C, chromosome 13 at 23,585,770 bp (GRCm38)
  • A to C, chromosome 13 at 58,100,398 bp (GRCm38)
  • G to A, chromosome 13 at 86,046,718 bp (GRCm38)
  • A to G, chromosome 13 at 92,523,055 bp (GRCm38)
  • A to T, chromosome 13 at 112,714,243 bp (GRCm38)
  • A to G, chromosome 14 at 18,285,203 bp (GRCm38)
  • T to C, chromosome 14 at 21,625,188 bp (GRCm38)
  • A to T, chromosome 14 at 117,186,676 bp (GRCm38)
  • A to G, chromosome 15 at 82,392,002 bp (GRCm38)
  • A to G, chromosome 16 at 75,562,271 bp (GRCm38)
  • A to G, chromosome 19 at 9,009,785 bp (GRCm38)
  • A to T, chromosome 19 at 13,411,111 bp (GRCm38)
  • T to C, chromosome 19 at 13,795,416 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9112 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069002-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.