Loading Mouse GIF
Loading...

Strain Name:
C57BL/6J-MtgxR9213Btlr/Mmmh
Stock Number:
069050-MU
Citation ID:
RRID:MMRRC_069050-MU
Other Names:
R9213 (G1)
Major Collection:

Strain Information

Rptor
Name: regulatory associated protein of MTOR, complex 1
Synonyms: raptor, 4932417H02Rik, Rap
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 74370
Homologene: 80210
Ssbp4
Name: single stranded DNA binding protein 4
Synonyms: 1210002E11Rik, Ssdp4
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 76900
Homologene: 41881
Sec23a
Name: SEC23 homolog A, COPII coat complex component
Synonyms: Sec23r, Msec23
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 20334
Homologene: 4642
Zfhx3
Name: zinc finger homeobox 3
Synonyms: WBP9, A230102L03Rik, Atbf1, Sci
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 11906
HGNC: HGNC:777
Homologene: 21366
Mon2
Name: MON2 homolog, regulator of endosome to Golgi trafficking
Synonyms: SF21, 2610528O22Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 67074
VEGA: 10
Homologene: 44309
Safb2
Name: scaffold attachment factor B2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224902
Homologene: 35210
Fanci
Name: Fanconi anemia, complementation group I
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 208836
Homologene: 49530
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to C, chromosome 1 at 91,554,809 bp (GRCm38)
  • C to T, chromosome 1 at 166,494,573 bp (GRCm38)
  • A to G, chromosome 1 at 180,905,908 bp (GRCm38)
  • T to C, chromosome 1 at 181,616,640 bp (GRCm38)
  • A to G, chromosome 1 at 192,930,506 bp (GRCm38)
  • A to G, chromosome 2 at 4,603,561 bp (GRCm38)
  • A to G, chromosome 2 at 28,453,637 bp (GRCm38)
  • T to C, chromosome 2 at 33,005,068 bp (GRCm38)
  • T to A, chromosome 2 at 111,190,354 bp (GRCm38)
  • G to T, chromosome 2 at 166,575,749 bp (GRCm38)
  • T to A, chromosome 3 at 62,432,579 bp (GRCm38)
  • A to C, chromosome 3 at 75,298,112 bp (GRCm38)
  • G to T, chromosome 4 at 11,609,321 bp (GRCm38)
  • T to A, chromosome 4 at 119,281,597 bp (GRCm38)
  • T to A, chromosome 5 at 76,245,529 bp (GRCm38)
  • T to A, chromosome 5 at 110,619,242 bp (GRCm38)
  • T to C, chromosome 5 at 116,190,126 bp (GRCm38)
  • C to T, chromosome 5 at 134,706,602 bp (GRCm38)
  • T to C, chromosome 6 at 3,376,856 bp (GRCm38)
  • T to TCCC, chromosome 6 at 4,756,451 bp (GRCm38)
  • G to A, chromosome 6 at 48,463,935 bp (GRCm38)
  • T to C, chromosome 6 at 56,743,456 bp (GRCm38)
  • T to A, chromosome 6 at 56,779,932 bp (GRCm38)
  • A to T, chromosome 7 at 4,580,912 bp (GRCm38)
  • A to G, chromosome 7 at 19,524,084 bp (GRCm38)
  • A to G, chromosome 7 at 43,999,004 bp (GRCm38)
  • T to A, chromosome 7 at 79,406,223 bp (GRCm38)
  • T to C, chromosome 7 at 99,451,738 bp (GRCm38)
  • T to C, chromosome 8 at 22,148,661 bp (GRCm38)
  • G to T, chromosome 8 at 70,599,745 bp (GRCm38)
  • T to C, chromosome 8 at 104,261,493 bp (GRCm38)
  • C to G, chromosome 8 at 105,973,613 bp (GRCm38)
  • T to A, chromosome 8 at 108,950,124 bp (GRCm38)
  • T to G, chromosome 8 at 109,996,188 bp (GRCm38)
  • G to T, chromosome 9 at 7,475,363 bp (GRCm38)
  • G to T, chromosome 9 at 18,312,493 bp (GRCm38)
  • T to A, chromosome 9 at 38,109,130 bp (GRCm38)
  • C to A, chromosome 9 at 38,403,751 bp (GRCm38)
  • T to C, chromosome 9 at 59,865,639 bp (GRCm38)
  • T to C, chromosome 9 at 105,397,095 bp (GRCm38)
  • T to C, chromosome 10 at 43,022,378 bp (GRCm38)
  • G to T, chromosome 10 at 123,036,111 bp (GRCm38)
  • A to G, chromosome 11 at 59,213,360 bp (GRCm38)
  • T to C, chromosome 11 at 69,364,802 bp (GRCm38)
  • G to A, chromosome 11 at 102,287,649 bp (GRCm38)
  • A to G, chromosome 11 at 108,486,953 bp (GRCm38)
  • T to C, chromosome 11 at 119,603,939 bp (GRCm38)
  • A to T, chromosome 12 at 59,001,922 bp (GRCm38)
  • A to G, chromosome 12 at 65,019,132 bp (GRCm38)
  • T to A, chromosome 13 at 40,717,399 bp (GRCm38)
  • T to A, chromosome 13 at 104,444,932 bp (GRCm38)
  • A to G, chromosome 15 at 44,495,478 bp (GRCm38)
  • C to A, chromosome 15 at 65,889,708 bp (GRCm38)
  • T to C, chromosome 15 at 76,125,222 bp (GRCm38)
  • A to T, chromosome 16 at 10,501,878 bp (GRCm38)
  • T to C, chromosome 16 at 20,720,535 bp (GRCm38)
  • T to A, chromosome 17 at 12,877,030 bp (GRCm38)
  • A to G, chromosome 17 at 35,515,002 bp (GRCm38)
  • T to A, chromosome 17 at 56,575,602 bp (GRCm38)
  • C to A, chromosome 18 at 36,739,331 bp (GRCm38)
  • A to G, chromosome 18 at 49,723,732 bp (GRCm38)
  • C to T, chromosome 19 at 54,027,800 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain GQC Summary
Gene Specific Genotyping:

To request gene-specific and other genotyping services for a strain, please contact the distribution MMRRC Center for more information.

Background Genetic Quality:

The MMRRC has developed a Genetic Quality Control pipeline using the MiniMUGA array to provide additional information to identify and validate genetic backgrounds of MMRRC strains. For more information on whether genetic background data is available, please contact MMRRC_GeneticQC@med.unc.edu. Note: that MiniMUGA genetic background data is not available on all strains, but can be ordered if desired.

Suggested Control Mice
Littermates of all relevant genotypes.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9213 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.


Disclaimer: If MMRRC Strain Genetic Quality Control (GQC; based on MiniMUGA genotyping and analysis) has been completed for this strain, the information might differ from the genetic background information provided by the submitter. MiniMUGA genetic analysis is done on a strain’s tissue samples taken when archived by or ordered from the assigned MMRRC Center.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069050-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.