Strain Name:
C57BL/6J-MtgxR9213Btlr/Mmmh
Stock Number:
069050-MU
Citation ID:
RRID:MMRRC_069050-MU
Other Names:
R9213 (G1)
Major Collection:

Strain Information

Rptor
Name: regulatory associated protein of MTOR, complex 1
Synonyms: Rap, 4932417H02Rik, raptor
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 74370
Homologene: 80210
Ssbp4
Name: single stranded DNA binding protein 4
Synonyms: Ssdp4, 1210002E11Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 76900
Homologene: 41881
Sec23a
Name: SEC23 homolog A, COPII coat complex component
Synonyms: Sec23r, Msec23
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 20334
Homologene: 4642
Zfhx3
Name: zinc finger homeobox 3
Synonyms: A230102L03Rik, Atbf1, Sci, WBP9
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 11906
HGNC: HGNC:777
Homologene: 21366
Mon2
Name: MON2 homolog, regulator of endosome to Golgi trafficking
Synonyms: SF21, 2610528O22Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 67074
VEGA: 10
Homologene: 44309
Safb2
Name: scaffold attachment factor B2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224902
Homologene: 35210
Fanci
Name: Fanconi anemia, complementation group I
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 208836
Homologene: 49530
Ccdc60
Name: coiled-coil domain containing 60
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 269693
Homologene: 18624
Cklf
Name: chemokine-like factor
Synonyms: chemokine-like factor 4, Cklf6, CKLF5, HSPC224, UCK-1, CKLF4, CKLF3, CKLF2, CKLF1, C32, 1700001C14Rik, A730028G07Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 75458
Homologene: 9663
Myo9a
Name: myosin IXa
Synonyms: C130068I12Rik, 4732465J09Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 270163
HGNC: HGNC:7608
Homologene: 21371
Clock
Name: clock circadian regulator
Synonyms: KAT13D, 5330400M04Rik, bHLHe8
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 12753
HGNC: HGNC:2082
Homologene: 3603
Galnt9
Name: polypeptide N-acetylgalactosaminyltransferase 9
Synonyms: GalNAc-T9
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231605
HGNC: HGNC:4131
Homologene: 72793
Syt14
Name: synaptotagmin XIV
Synonyms: B230320I09Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 329324
Homologene: 17719
Shoc2
Name: Shoc2, leucine rich repeat scaffold protein
Synonyms: soc-2 (suppressor of clear) homolog (C. elegans), Sur-8
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 56392
VEGA: 19
Homologene: 7219
Ybx1
Name: Y box protein 1
Synonyms: YB-1, DNA binding protein B, EF1A, dbpB, Nsep1, MSY1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 22608
HGNC: HGNC:8014
Homologene: 88707
Tfap2a
Name: transcription factor AP-2, alpha
Synonyms: AP-2 alpha, Tcfap2a, Ap2tf, Ap2, AP2alpha, Ap-2 (a)
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 21418
VEGA: 13
Homologene: 2421
Gdpd5
Name: glycerophosphodiester phosphodiesterase domain containing 5
Synonyms: Gde2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233552
Homologene: 32741
Arf1
Name: ADP-ribosylation factor 1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 11840
HGNC: HGNC:652
Homologene: 133930
Chordc1
Name: cysteine and histidine rich domain containing 1
Synonyms: 1110001O09Rik, morgana, Chp-1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 66917
VEGA: 9
Homologene: 8111
Garnl3
Name: GTPase activating RANGAP domain-like 3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 99326
Homologene: 13003
Rad54b
Name: RAD54 homolog B (S. cerevisiae)
Synonyms: E130016E03Rik, E130016E03Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 623474
Homologene: 8240
Tmub2
Name: transmembrane and ubiquitin-like domain containing 2
Synonyms: 2010008E23Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 72053
Homologene: 18581
Kbtbd2
Name: kelch repeat and BTB (POZ) domain containing 2
Synonyms: Bklhd1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 210973
Homologene: 17122
Peg10
Name: paternally expressed 10
Synonyms: HB-1, Edr, MyEF-3 like, MEF3L, Mart2, Rtl2, MyEF-3, Mar2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 170676
Homologene: 116067
Ciita
Name: class II transactivator
Synonyms: Gm9475, C2ta
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 12265
VEGA: 16
HGNC: HGNC:7067
Homologene: 207
Adamts6
Name: ADAM metallopeptidase with thrombospondin type 1 motif 6
Synonyms: b2b2182Clo, b2b2187.1Clo, ADAM-TS6, b2b1879.1Clo, A930019D11Rik, b2b2029Clo, b2b2228Clo
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 108154
VEGA: 13
HGNC: HGNC:222
Homologene: 82573
Nek3
Name: NIMA (never in mitosis gene a)-related expressed kinase 3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 23954
HGNC: HGNC:7746
Homologene: 1869
Avl9
Name: AVL9 cell migration associated
Synonyms: D730049P16Rik, 5830411G16Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 78937
Homologene: 62425
Nkpd1
Name: NTPase, KAP family P-loop domain containing 1
Synonyms: 2310015G09Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 69547
Homologene: 18876
Or8b101
Name: olfactory receptor family 8 subfamily B member 101
Synonyms: MOR162-4, GA_x6K02T2PVTD-31787920-31788864, Olfr888
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258416
Homologene: 84577
Pkhd1l1
Name: polycystic kidney and hepatic disease 1-like 1
Synonyms: D86 mRNA, PKHDL1, fibrocystin L
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 192190
Homologene: 16332
Dnah14
Name: dynein, axonemal, heavy chain 14
Synonyms: LOC381311, Gm980, A230079K17Rik, Dnahc14
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 240960
HGNC: HGNC:2945
Homologene: 90078
Chd3
Name: chromodomain helicase DNA binding protein 3
Synonyms: Prp9-1, Chd7, 2600010P09Rik, Mi-2 alpha, Prp7
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216848
HGNC: HGNC:1918
Homologene: 62693
Oc90
Name: otoconin 90
Synonyms: PLA2L, Ocn-95, Pla2ll
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 18256
HGNC: HGNC:8100
Homologene: 19021
Ptprh
Name: protein tyrosine phosphatase receptor type H
Synonyms: SAP-1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 545902
HGNC: HGNC:9672
Homologene: 37693
BC024139
Name: cDNA sequence BC024139
Synonyms: 6230424I18Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 271278
Homologene: 129974
Aste1
Name: asteroid homolog 1
Synonyms: 1100001A21Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 66595
Homologene: 130666
Eln
Name: elastin
Synonyms: tropoelastin, E030024M20Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 13717
HGNC: HGNC:3327
Frmd4a
Name: FERM domain containing 4A
Synonyms: Gm13190, 2700017I06Rik, C230040M21Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 209630
Homologene: 9971
Tmco6
Name: transmembrane and coiled-coil domains 6
Synonyms: 2410015B03Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 71983
VEGA: 18
Homologene: 12431
Sobp
Name: sine oculis binding protein
Synonyms: 5330439J01Rik, jc, Jxc1, 2900009C16Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 109205
Homologene: 41216
Sspo
Name: SCO-spondin
Synonyms: Scospondin, C79529
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243369
Homologene: 45453
Mmp1a
Name: matrix metallopeptidase 1a (interstitial collagenase)
Synonyms: Mcol-A
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 83995
VEGA: 9
HGNC: HGNC:7155
Homologene: 20544
Samd9l
Name: sterile alpha motif domain containing 9-like
Synonyms: ESTM25
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 209086
HGNC: HGNC:1349
Homologene: 7707
Klk1b11
Name: kallikrein 1-related peptidase b11
Synonyms: mGK-11, Klk11
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 16613
Homologene: 68141
Arhgef26
Name: Rho guanine nucleotide exchange factor 26
Synonyms: 8430436L14Rik, 4631416L12Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 622434
Homologene: 9204
Prex1
Name: phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
Synonyms: P-REX1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 277360
Homologene: 10821
Tcf19
Name: transcription factor 19
Synonyms: 5730403J10Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 106795
Homologene: 5156
Mrgprh
Name: MAS-related GPR, member H
Synonyms: MrgH, Gpr90
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 80978
VEGA: 17
Homologene: 12758
Dpep3
Name: dipeptidase 3
Synonyms: MBD-3, 1700018F16Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 71854
Homologene: 23357
Togaram1
Name: TOG array regulator of axonemal microtubules 1
Synonyms: A430041B07Rik, Fam179b
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 328108
VEGA: 12
Homologene: 15025
Tat
Name: tyrosine aminotransferase
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234724
Homologene: 37293
Gm4846
Name: predicted gene 4846
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226601
Homologene: 136281
Ppp1r26
Name: protein phosphatase 1, regulatory subunit 26
Synonyms: LOC241289
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241289
Homologene: 49400
Dtwd2
Name: DTW domain containing 2
Synonyms: 1190002H09Rik, 8030470C17Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 68857
Homologene: 79701
Potefam1
Name: POTE ankyrin domain family member 1
Synonyms: Potea, Pote1, A26c3, 4930430A15Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 67575
Homologene: 69410
Cep112
Name: centrosomal protein 112
Synonyms: 1700001M19Rik, 1700029K01Rik, Ccdc46, 8430407H02Rik, Macoco
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 76380
Homologene: 44915
Polr2h
Name: polymerase (RNA) II (DNA directed) polypeptide H
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 245841
HGNC: HGNC:9195
Homologene: 4540
Or8b3
Name: olfactory receptor family 8 subfamily B member 3
Synonyms: Olfr147, M3, MOR164-1, GA_x6K02T2PVTD-32098059-32099003
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258869
VEGA: 9
Homologene: 128279
Asb1
Name: ankyrin repeat and SOCS box-containing 1
Synonyms: 1700054C17Rik, 1700029O08Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 65247
Homologene: 9390
Pycr2
Name: pyrroline-5-carboxylate reductase family, member 2
Synonyms: 1810018M05Rik, P5cr2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 69051
Homologene: 8343
Wdr49
Name: WD repeat domain 49
Synonyms: EG213248
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 213248
Homologene: 18714
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to C, chromosome 1 at 91,554,809 bp (GRCm38)
  • C to T, chromosome 1 at 166,494,573 bp (GRCm38)
  • A to G, chromosome 1 at 180,905,908 bp (GRCm38)
  • T to C, chromosome 1 at 181,616,640 bp (GRCm38)
  • A to G, chromosome 1 at 192,930,506 bp (GRCm38)
  • A to G, chromosome 2 at 4,603,561 bp (GRCm38)
  • A to G, chromosome 2 at 28,453,637 bp (GRCm38)
  • T to C, chromosome 2 at 33,005,068 bp (GRCm38)
  • T to A, chromosome 2 at 111,190,354 bp (GRCm38)
  • G to T, chromosome 2 at 166,575,749 bp (GRCm38)
  • T to A, chromosome 3 at 62,432,579 bp (GRCm38)
  • A to C, chromosome 3 at 75,298,112 bp (GRCm38)
  • G to T, chromosome 4 at 11,609,321 bp (GRCm38)
  • T to A, chromosome 4 at 119,281,597 bp (GRCm38)
  • T to A, chromosome 5 at 76,245,529 bp (GRCm38)
  • T to A, chromosome 5 at 110,619,242 bp (GRCm38)
  • T to C, chromosome 5 at 116,190,126 bp (GRCm38)
  • C to T, chromosome 5 at 134,706,602 bp (GRCm38)
  • T to C, chromosome 6 at 3,376,856 bp (GRCm38)
  • T to TCCC, chromosome 6 at 4,756,451 bp (GRCm38)
  • G to A, chromosome 6 at 48,463,935 bp (GRCm38)
  • T to C, chromosome 6 at 56,743,456 bp (GRCm38)
  • T to A, chromosome 6 at 56,779,932 bp (GRCm38)
  • A to T, chromosome 7 at 4,580,912 bp (GRCm38)
  • A to G, chromosome 7 at 19,524,084 bp (GRCm38)
  • A to G, chromosome 7 at 43,999,004 bp (GRCm38)
  • T to A, chromosome 7 at 79,406,223 bp (GRCm38)
  • T to C, chromosome 7 at 99,451,738 bp (GRCm38)
  • T to C, chromosome 8 at 22,148,661 bp (GRCm38)
  • G to T, chromosome 8 at 70,599,745 bp (GRCm38)
  • T to C, chromosome 8 at 104,261,493 bp (GRCm38)
  • C to G, chromosome 8 at 105,973,613 bp (GRCm38)
  • T to A, chromosome 8 at 108,950,124 bp (GRCm38)
  • T to G, chromosome 8 at 109,996,188 bp (GRCm38)
  • G to T, chromosome 9 at 7,475,363 bp (GRCm38)
  • G to T, chromosome 9 at 18,312,493 bp (GRCm38)
  • T to A, chromosome 9 at 38,109,130 bp (GRCm38)
  • C to A, chromosome 9 at 38,403,751 bp (GRCm38)
  • T to C, chromosome 9 at 59,865,639 bp (GRCm38)
  • T to C, chromosome 9 at 105,397,095 bp (GRCm38)
  • T to C, chromosome 10 at 43,022,378 bp (GRCm38)
  • G to T, chromosome 10 at 123,036,111 bp (GRCm38)
  • A to G, chromosome 11 at 59,213,360 bp (GRCm38)
  • T to C, chromosome 11 at 69,364,802 bp (GRCm38)
  • G to A, chromosome 11 at 102,287,649 bp (GRCm38)
  • A to G, chromosome 11 at 108,486,953 bp (GRCm38)
  • T to C, chromosome 11 at 119,603,939 bp (GRCm38)
  • A to T, chromosome 12 at 59,001,922 bp (GRCm38)
  • A to G, chromosome 12 at 65,019,132 bp (GRCm38)
  • T to A, chromosome 13 at 40,717,399 bp (GRCm38)
  • T to A, chromosome 13 at 104,444,932 bp (GRCm38)
  • A to G, chromosome 15 at 44,495,478 bp (GRCm38)
  • C to A, chromosome 15 at 65,889,708 bp (GRCm38)
  • T to C, chromosome 15 at 76,125,222 bp (GRCm38)
  • A to T, chromosome 16 at 10,501,878 bp (GRCm38)
  • T to C, chromosome 16 at 20,720,535 bp (GRCm38)
  • T to A, chromosome 17 at 12,877,030 bp (GRCm38)
  • A to G, chromosome 17 at 35,515,002 bp (GRCm38)
  • T to A, chromosome 17 at 56,575,602 bp (GRCm38)
  • C to A, chromosome 18 at 36,739,331 bp (GRCm38)
  • A to G, chromosome 18 at 49,723,732 bp (GRCm38)
  • C to T, chromosome 19 at 54,027,800 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9213 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069050-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.