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Strain Name:
C57BL/6J-MtgxR9235Btlr/Mmmh
Stock Number:
069065-MU
Citation ID:
RRID:MMRRC_069065-MU
Other Names:
R9235 (G1)
Major Collection:

Strain Information

Kmt2c
Name: lysine (K)-specific methyltransferase 2C
Synonyms: E330008K23Rik, HALR, Mll3
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231051
Homologene: 46480
Nlgn3
Name: neuroligin 3
Synonyms: HNL3, A230085M13Rik, NL3, NLG3
Type: Gene
Species: Mouse
Chromosome: X
NCBI: 245537
Homologene: 23133
Ubr5
Name: ubiquitin protein ligase E3 component n-recognin 5
Synonyms: 4432411E13Rik, Edd1, Edd
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 70790
VEGA: 15
Homologene: 9295
Prkdc
Name: protein kinase, DNA activated, catalytic polypeptide
Synonyms: DNA-PKcs, slip, DNAPDcs, XRCC7, DNA-PK, DOXNPH, dxnph
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 19090
HGNC: HGNC:9413
Homologene: 5037
Morc3
Name: microrchidia 3
Synonyms: 1110051N18Rik, D16Jhu32e, 1110051N18Rik, Zcwcc3
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 338467
Homologene: 32257
Ccnb2
Name: cyclin B2
Synonyms: CycB2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 12442
VEGA: 9
HGNC: HGNC:1580
Homologene: 74359
Dis3l2
Name: DIS3 like 3'-5' exoribonuclease 2
Synonyms: 8030493P09Rik, 4930429A22Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 208718
Homologene: 62417
Wdr3
Name: WD repeat domain 3
Synonyms: D030020G18Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 269470
Homologene: 4937
Mdn1
Name: midasin AAA ATPase 1
Synonyms: LOC213784, 4833432B22Rik, D4Abb1e
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100019
Homologene: 39689
Mrpl49
Name: mitochondrial ribosomal protein L49
Synonyms: 4833419D18Rik, Nof1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 18120
VEGA: 19
HGNC: HGNC:1176
Homologene: 37982
Pikfyve
Name: phosphoinositide kinase, FYVE type zinc finger containing
Synonyms: 5230400C17Rik, Pip5k3, PipkIII
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 18711
Homologene: 32115
Cd2
Name: CD2 antigen
Synonyms: LFA-2, Ly37, Ly-37
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 12481
HGNC: HGNC:1639
Homologene: 1338
Cwf19l1
Name: CWF19 like cell cycle control factor 1
Synonyms: 2610528C06Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 72502
VEGA: 19
Homologene: 41244
Tmco1
Name: transmembrane and coiled-coil domains 1
Synonyms: ESTM39, 1190006A08Rik, 4930403O06Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 68944
Homologene: 10384
Flt3
Name: FMS-like tyrosine kinase 3
Synonyms: CD135, Flk-2, Flt-3, Flk2, wmfl
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 14255
HGNC: HGNC:3765
Homologene: 3040
Fign
Name: fidgetin
Synonyms: Fgn
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 60344
Homologene: 5813
Dmpk
Name: dystrophia myotonica-protein kinase
Synonyms: DM, Dm15
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 13400
HGNC: HGNC:2933
Homologene: 3247
Fat3
Name: FAT atypical cadherin 3
Synonyms: LOC234973, LOC382129, 9430076A06Rik, D430038H04Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 270120
VEGA: 9
Homologene: 82252
Mlxipl
Name: MLX interacting protein-like
Synonyms: WS-bHLH, ChREBP, Wbscr14, bHLHd14
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 58805
Homologene: 32507
Klra3
Name: killer cell lectin-like receptor, subfamily A, member 3
Synonyms: 5E6, Ly49C, Nk-2, Ly49c, NK-2.1, Nk2.1, Nk2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16634
Homologene: 110821
Gm11639
Name: predicted gene 11639
Synonyms: Gm11639, Efcab15
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 105242472
Ulk4
Name: unc-51-like kinase 4
Synonyms: 4932415A06Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 209012
Homologene: 41205
Ttc21a
Name: tetratricopeptide repeat domain 21A
Synonyms: 4921538N17Rik, Thm2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 74052
Homologene: 14728
Frmd4a
Name: FERM domain containing 4A
Synonyms: C230040M21Rik, 2700017I06Rik, Gm13190
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 209630
Homologene: 9971
Ptprn2
Name: protein tyrosine phosphatase receptor type N polypeptide 2
Synonyms: PTP-NP, IA-2 beta, phogrin, IA-2beta, 4930425H11Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 19276
HGNC: HGNC:9677
Homologene: 2134
Unc13a
Name: unc-13 homolog A
Synonyms: Munc13-1, 2410078G03Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 382018
Homologene: 11279
Plbd2
Name: phospholipase B domain containing 2
Synonyms: 66.3 kDa, p76, 1300012G16Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 71772
Homologene: 41528
Sspo
Name: SCO-spondin
Synonyms: C79529, Scospondin
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243369
Homologene: 45453
Slc34a2
Name: solute carrier family 34 (sodium phosphate), member 2
Synonyms: type IIb Na/Picotransporter, Npt2b, NaPi-2b, D5Ertd227e
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 20531
Homologene: 2297
Trim28
Name: tripartite motif-containing 28
Synonyms: KRIP-1, KAP-1, Tif1b, MommeD9
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 21849
Homologene: 21175
Nrap
Name: nebulin-related anchoring protein
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 18175
HGNC: HGNC:7988
Homologene: 4499
Zfp986
Name: zinc finger protein 986
Synonyms: Gm13235
Type: Gene
Species: Mouse
Chromosome: 4
C2
Name: complement C2
Synonyms: classical-complement pathway C3/C5 convertase
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 12263
HGNC: HGNC:1248
Homologene: 45
Sema5a
Name: sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
Synonyms: M-Sema D, semF, Semaf, 9130201M22Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 20356
VEGA: 15
Homologene: 2949
Slc6a13
Name: solute carrier family 6 (neurotransmitter transporter, GABA), member 13
Synonyms: Gabt3, Gat2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 14412
Homologene: 9592
Myom3
Name: myomesin family, member 3
Synonyms: 8430427K15Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242702
Homologene: 19432
Vmn1r25
Name: vomeronasal 1 receptor 25
Synonyms: V1rc8
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 113865
Homologene: 137652
Or6c8b
Name: olfactory receptor family 6 subfamily C member 8B
Synonyms: GA_x6K02T2PULF-10732607-10731678, MOR115-4, Olfr765
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 544748
Homologene: 105186
Vmn2r101
Name: vomeronasal 2, receptor 101
Synonyms: EG627576
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 627576
Homologene: 115024
Plekhd1
Name: pleckstrin homology domain containing, family D (with coiled-coil domains) member 1
Synonyms: 3830431G21Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217682
Homologene: 15090
Or5t5
Name: olfactory receptor family 5 subfamily T member 5
Synonyms: GA_x6K02T2Q125-48278396-48279364, MOR179-6, Olfr1093
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258363
Homologene: 133610
Pank1
Name: pantothenate kinase 1
Synonyms: 5430426F23Rik, Pank1b, Pank1a, Pank1, 4632412I06Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 75735
VEGA: 19
HGNC: HGNC:8598
Homologene: 56979
Psme3
Name: proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)
Synonyms: Ki, pa28g, PA28gamma, REGgamma
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 19192
HGNC: HGNC:9570
Homologene: 2111
Zfp28
Name: zinc finger protein 28
Synonyms: mkr-5, Zfp-28, 2810438M17Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 22690
Homologene: 69047
Or5d43
Name: olfactory receptor family 5 subfamily D member 43
Synonyms: GA_x6K02T2Q125-49759783-49758845, MOR174-20_p, Olfr1173
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 404329
Homologene: 128091
Dnajb12
Name: DnaJ heat shock protein family (Hsp40) member B12
Synonyms: mDj10
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 56709
Homologene: 9749
Smyd4
Name: SET and MYND domain containing 4
Synonyms: G430029E23Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 319822
Homologene: 35098
4921524L21Rik
Name: RIKEN cDNA 4921524L21 gene
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 70901
VEGA: 18
Homologene: 78009
Klk15
Name: kallikrein related-peptidase 15
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 317652
Homologene: 77571
Ugt1a2
Name: UDP glucuronosyltransferase 1 family, polypeptide A2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 22236
Homologene: 86211
Or14a257
Name: olfactory receptor family 14 subfamily A member 257
Synonyms: GA_x6K02T2NHDJ-9619796-9620794, MOR219-4, Olfr298
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 257905
Catsper4
Name: cation channel, sperm associated 4
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 329954
Homologene: 18638
Islr
Name: immunoglobulin superfamily containing leucine-rich repeat
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 26968
VEGA: 9
HGNC: HGNC:6133
Homologene: 4050
Klrb1b
Name: killer cell lectin-like receptor subfamily B member 1B
Synonyms: Nkrp1-b, NKR-P1D, Ly55d, Ly55b, Nkrp1d, NKR-P1B, Klrb1d
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 80782
HGNC: HGNC:6373
Homologene: 84369
Fbxo27
Name: F-box protein 27
Synonyms: LOC233040, FBG5, E130008B10Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233040
Homologene: 135640
Uqcc6
Name: ubiquinol-cytochrome c reductase complex assembly factor 6
Synonyms: 1190007I07Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 544717
Homologene: 87608
Plscr5
Name: phospholipid scramblase family, member 5
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 100504689
Homologene: 28688
4930558K02Rik
Name: RIKEN cDNA 4930558K02 gene
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 75368
Homologene: 51403
Igkv4-53
Name: immunoglobulin kappa variable 4-53
Synonyms: LOC385259, LOC384516
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 546213
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • C to A, chromosome 1 at 65,260,029 bp (GRCm38)
  • G to A, chromosome 1 at 86,821,339 bp (GRCm38)
  • A to G, chromosome 1 at 88,200,766 bp (GRCm38)
  • T to C, chromosome 1 at 161,952,603 bp (GRCm38)
  • C to T, chromosome 1 at 167,308,563 bp (GRCm38)
  • G to A, chromosome 2 at 4,594,555 bp (GRCm38)
  • A to G, chromosome 2 at 63,980,563 bp (GRCm38)
  • T to C, chromosome 2 at 86,786,204 bp (GRCm38)
  • A to T, chromosome 2 at 88,274,380 bp (GRCm38)
  • T to A, chromosome 3 at 100,146,707 bp (GRCm38)
  • A to G, chromosome 3 at 101,287,843 bp (GRCm38)
  • C to A, chromosome 4 at 32,739,122 bp (GRCm38)
  • C to T, chromosome 4 at 134,227,295 bp (GRCm38)
  • T to A, chromosome 4 at 135,814,342 bp (GRCm38)
  • T to A, chromosome 4 at 145,899,189 bp (GRCm38)
  • T to C, chromosome 5 at 25,299,999 bp (GRCm38)
  • A to T, chromosome 5 at 53,069,325 bp (GRCm38)
  • T to A, chromosome 5 at 120,488,489 bp (GRCm38)
  • C to A, chromosome 5 at 135,128,687 bp (GRCm38)
  • T to C, chromosome 5 at 147,383,392 bp (GRCm38)
  • T to A, chromosome 6 at 48,489,784 bp (GRCm38)
  • A to G, chromosome 6 at 57,978,503 bp (GRCm38)
  • A to T, chromosome 6 at 69,649,317 bp (GRCm38)
  • A to G, chromosome 6 at 121,325,025 bp (GRCm38)
  • A to G, chromosome 6 at 128,818,584 bp (GRCm38)
  • A to T, chromosome 6 at 130,334,255 bp (GRCm38)
  • A to T, chromosome 7 at 6,394,606 bp (GRCm38)
  • G to A, chromosome 7 at 13,029,563 bp (GRCm38)
  • T to G, chromosome 7 at 19,088,216 bp (GRCm38)
  • T to A, chromosome 7 at 28,698,331 bp (GRCm38)
  • C to T, chromosome 7 at 43,938,366 bp (GRCm38)
  • A to T, chromosome 7 at 86,489,098 bp (GRCm38)
  • G to T, chromosome 8 at 71,663,268 bp (GRCm38)
  • T to A, chromosome 9 at 15,922,378 bp (GRCm38)
  • T to A, chromosome 9 at 58,157,661 bp (GRCm38)
  • A to G, chromosome 9 at 70,410,881 bp (GRCm38)
  • A to G, chromosome 9 at 92,204,364 bp (GRCm38)
  • G to T, chromosome 9 at 119,945,493 bp (GRCm38)
  • G to A, chromosome 9 at 121,152,151 bp (GRCm38)
  • C to T, chromosome 10 at 59,892,977 bp (GRCm38)
  • A to T, chromosome 10 at 82,622,752 bp (GRCm38)
  • G to T, chromosome 10 at 129,046,182 bp (GRCm38)
  • G to A, chromosome 11 at 75,404,863 bp (GRCm38)
  • A to T, chromosome 11 at 101,320,768 bp (GRCm38)
  • A to G, chromosome 11 at 105,017,161 bp (GRCm38)
  • T to A, chromosome 12 at 80,722,017 bp (GRCm38)
  • G to A, chromosome 12 at 117,269,651 bp (GRCm38)
  • A to G, chromosome 15 at 32,618,888 bp (GRCm38)
  • A to G, chromosome 15 at 38,045,738 bp (GRCm38)
  • T to C, chromosome 15 at 76,175,501 bp (GRCm38)
  • T to A, chromosome 16 at 15,833,887 bp (GRCm38)
  • T to C, chromosome 16 at 93,862,433 bp (GRCm38)
  • T to A, chromosome 17 at 19,589,976 bp (GRCm38)
  • T to C, chromosome 17 at 34,864,869 bp (GRCm38)
  • T to A, chromosome 18 at 6,623,518 bp (GRCm38)
  • G to A, chromosome 19 at 6,055,117 bp (GRCm38)
  • C to A, chromosome 19 at 34,878,797 bp (GRCm38)
  • G to A, chromosome 19 at 44,124,836 bp (GRCm38)
  • A to T, chromosome 19 at 56,342,328 bp (GRCm38)
  • T to C, chromosome X at 101,308,784 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9235 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069065-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.