Loading Mouse GIF
Loading...

Strain Name:
C57BL/6J-MtgxR9301Btlr/Mmmh
Stock Number:
069117-MU
Citation ID:
RRID:MMRRC_069117-MU
Other Names:
R9301 (G1)
Major Collection:

Strain Information

Ptk2
Name: PTK2 protein tyrosine kinase 2
Synonyms: Fadk, FAK, FRNK
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 14083
VEGA: 15
HGNC: HGNC:9611
Homologene: 7314
Slc29a1
Name: solute carrier family 29 (nucleoside transporters), member 1
Synonyms: ENT1, NBMPR-sensitive equilibrative nucleoside transporter, 1200014D21Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 63959
Homologene: 37985
Ltbp4
Name: latent transforming growth factor beta binding protein 4
Synonyms: 2310046A13Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 108075
HGNC: HGNC:6717
Homologene: 2645
Pik3c2a
Name: phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha
Synonyms: PI3KC2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18704
HGNC: HGNC:8971
Homologene: 20581
Dock6
Name: dedicator of cytokinesis 6
Synonyms: 2410095B20Rik, 4931431C02Rik, C330023D02Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 319899
VEGA: 9
Homologene: 83291
Atad5
Name: ATPase family, AAA domain containing 5
Synonyms: LOC237877, C130052G03Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237877
Homologene: 32611
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to T, chromosome 1 at 63,065,810 bp (GRCm38)
  • T to A, chromosome 1 at 136,274,902 bp (GRCm38)
  • T to A, chromosome 1 at 158,845,044 bp (GRCm38)
  • A to C, chromosome 1 at 166,667,225 bp (GRCm38)
  • A to G, chromosome 1 at 191,997,528 bp (GRCm38)
  • T to A, chromosome 2 at 4,153,093 bp (GRCm38)
  • A to T, chromosome 2 at 37,201,243 bp (GRCm38)
  • A to G, chromosome 2 at 60,252,449 bp (GRCm38)
  • A to G, chromosome 2 at 76,017,873 bp (GRCm38)
  • A to G, chromosome 2 at 86,553,474 bp (GRCm38)
  • A to G, chromosome 2 at 87,942,953 bp (GRCm38)
  • A to G, chromosome 2 at 135,325,690 bp (GRCm38)
  • A to G, chromosome 2 at 148,751,006 bp (GRCm38)
  • A to G, chromosome 2 at 172,553,427 bp (GRCm38)
  • A to T, chromosome 2 at 178,381,857 bp (GRCm38)
  • C to T, chromosome 3 at 54,385,238 bp (GRCm38)
  • C to T, chromosome 3 at 67,290,347 bp (GRCm38)
  • T to A, chromosome 3 at 104,783,741 bp (GRCm38)
  • T to A, chromosome 3 at 122,087,479 bp (GRCm38)
  • T to C, chromosome 3 at 132,837,977 bp (GRCm38)
  • A to G, chromosome 4 at 11,192,881 bp (GRCm38)
  • A to T, chromosome 4 at 13,875,477 bp (GRCm38)
  • T to A, chromosome 4 at 119,185,547 bp (GRCm38)
  • A to G, chromosome 5 at 38,213,587 bp (GRCm38)
  • G to T, chromosome 5 at 87,460,523 bp (GRCm38)
  • C to A, chromosome 5 at 100,779,292 bp (GRCm38)
  • T to G, chromosome 5 at 127,596,748 bp (GRCm38)
  • A to C, chromosome 6 at 86,392,259 bp (GRCm38)
  • T to C, chromosome 7 at 25,291,692 bp (GRCm38)
  • T to A, chromosome 7 at 27,322,153 bp (GRCm38)
  • A to G, chromosome 7 at 98,846,589 bp (GRCm38)
  • A to G, chromosome 7 at 107,796,608 bp (GRCm38)
  • A to T, chromosome 7 at 116,346,178 bp (GRCm38)
  • T to C, chromosome 7 at 139,642,545 bp (GRCm38)
  • T to C, chromosome 8 at 33,600,010 bp (GRCm38)
  • G to A, chromosome 8 at 70,650,768 bp (GRCm38)
  • A to G, chromosome 8 at 71,403,040 bp (GRCm38)
  • T to A, chromosome 8 at 77,555,745 bp (GRCm38)
  • A to G, chromosome 8 at 128,363,378 bp (GRCm38)
  • T to C, chromosome 9 at 21,817,815 bp (GRCm38)
  • T to G, chromosome 9 at 108,445,855 bp (GRCm38)
  • T to G, chromosome 9 at 109,386,585 bp (GRCm38)
  • T to C, chromosome 10 at 51,480,705 bp (GRCm38)
  • T to G, chromosome 10 at 68,035,847 bp (GRCm38)
  • T to C, chromosome 10 at 125,231,011 bp (GRCm38)
  • T to C, chromosome 10 at 127,030,633 bp (GRCm38)
  • T to A, chromosome 11 at 23,472,951 bp (GRCm38)
  • T to C, chromosome 11 at 49,625,414 bp (GRCm38)
  • T to A, chromosome 11 at 80,096,019 bp (GRCm38)
  • C to T, chromosome 11 at 99,006,964 bp (GRCm38)
  • A to G, chromosome 12 at 21,300,111 bp (GRCm38)
  • A to G, chromosome 12 at 85,245,839 bp (GRCm38)
  • A to T, chromosome 12 at 98,882,033 bp (GRCm38)
  • A to T, chromosome 12 at 102,476,798 bp (GRCm38)
  • A to T, chromosome 12 at 112,636,448 bp (GRCm38)
  • T to A, chromosome 13 at 60,718,311 bp (GRCm38)
  • T to A, chromosome 13 at 96,081,113 bp (GRCm38)
  • C to T, chromosome 14 at 30,676,855 bp (GRCm38)
  • T to A, chromosome 14 at 34,097,975 bp (GRCm38)
  • T to A, chromosome 14 at 55,719,626 bp (GRCm38)
  • T to C, chromosome 15 at 73,274,497 bp (GRCm38)
  • G to A, chromosome 15 at 76,540,206 bp (GRCm38)
  • T to A, chromosome 15 at 85,127,794 bp (GRCm38)
  • T to C, chromosome 15 at 89,457,683 bp (GRCm38)
  • A to G, chromosome 16 at 56,806,771 bp (GRCm38)
  • T to C, chromosome 17 at 29,850,538 bp (GRCm38)
  • A to G, chromosome 17 at 45,586,137 bp (GRCm38)
  • G to T, chromosome 18 at 77,781,238 bp (GRCm38)
  • A to T, chromosome 19 at 12,099,462 bp (GRCm38)
  • A to T, chromosome 19 at 25,411,434 bp (GRCm38)
  • A to G, chromosome 19 at 37,174,073 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain GQC Summary
Gene Specific Genotyping:

To request gene-specific and other genotyping services for a strain, please contact the distribution MMRRC Center for more information.

Background Genetic Quality:

The MMRRC has developed a Genetic Quality Control pipeline using the MiniMUGA array to provide additional information to identify and validate genetic backgrounds of MMRRC strains. For more information on whether genetic background data is available, please contact MMRRC_GeneticQC@med.unc.edu. Note: that MiniMUGA genetic background data is not available on all strains, but can be ordered if desired.

Suggested Control Mice
Littermates of all relevant genotypes.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9301 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.


Disclaimer: If MMRRC Strain Genetic Quality Control (GQC; based on MiniMUGA genotyping and analysis) has been completed for this strain, the information might differ from the genetic background information provided by the submitter. MiniMUGA genetic analysis is done on a strain’s tissue samples taken when archived by or ordered from the assigned MMRRC Center.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069117-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.