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Strain Name:
C57BL/6J-MtgxR9307Btlr/Mmmh
Stock Number:
069122-MU
Citation ID:
RRID:MMRRC_069122-MU
Other Names:
R9307 (G1)
Major Collection:

Strain Information

Pkd1
Name: polycystin 1, transient receptor potential channel interacting
Synonyms: polycystin-1, PC1, PC-1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 18763
VEGA: 17
HGNC: HGNC:9008
Homologene: 250
Utrn
Name: utrophin
Synonyms: G-utrophin, Dmdl, DRP
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 22288
VEGA: 10
Homologene: 21398
Prss12
Name: serine protease 12 neurotrypsin (motopsin)
Synonyms: Bssp-3, motopsin
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 19142
HGNC: HGNC:9477
Homologene: 7490
Btc
Name: betacellulin, epidermal growth factor family member
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 12223
HGNC: HGNC:1121
Homologene: 1309
Pcf11
Name: PCF11 cleavage and polyadenylation factor subunit
Synonyms: 5730417B17Rik, 2500001H09Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 74737
Homologene: 32282
Dgka
Name: diacylglycerol kinase, alpha
Synonyms: Dagk1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 13139
VEGA: 10
HGNC: HGNC:2849
Homologene: 1028
Adam23
Name: a disintegrin and metallopeptidase domain 23
Synonyms: MDC3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 23792
HGNC: HGNC:202
Homologene: 2826
Relch
Name: RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing
Synonyms: 2310035C23Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 227446
Homologene: 10834
Dock4
Name: dedicator of cytokinesis 4
Synonyms: EST N28122, 6330411N01Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238130
VEGA: 12
Homologene: 56680
Ins1
Name: insulin I
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 16333
VEGA: 19
HGNC: HGNC:6081
Homologene: 7383
Slc12a3
Name: solute carrier family 12, member 3
Synonyms: NCC, TSC
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 20497
Homologene: 287
Clock
Name: clock circadian regulator
Synonyms: 5330400M04Rik, KAT13D, bHLHe8
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 12753
HGNC: HGNC:2082
Homologene: 3603
Mcpt1
Name: mast cell protease 1
Synonyms: Mcp-1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 17224
VEGA: 14
Homologene: 137209
Dcaf6
Name: DDB1 and CUL4 associated factor 6
Synonyms: PC326, 1200006M05Rik, Iqwd1, NRIP
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 74106
Homologene: 10199
Dync1li1
Name: dynein cytoplasmic 1 light intermediate chain 1
Synonyms: LIC-1, 1110053F02Rik, Dnclic1, Dlic1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235661
VEGA: 9
Homologene: 9403
Zfp653
Name: zinc finger protein 653
Synonyms: E430039K05Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 319601
VEGA: 9
Homologene: 16346
Piezo1
Name: piezo-type mechanosensitive ion channel component 1
Synonyms: Piezo1, Fam38a
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234839
Homologene: 124356
Mturn
Name: maturin, neural progenitor differentiation regulator homolog (Xenopus)
Synonyms: B230212L03Rik, 2410066E13Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 68235
Cnbd1
Name: cyclic nucleotide binding domain containing 1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 435772
Homologene: 27843
Adam15
Name: ADAM metallopeptidase domain 15
Synonyms: metargidin, MDC15
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 11490
HGNC: HGNC:193
Homologene: 2829
Col13a1
Name: collagen, type XIII, alpha 1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 12817
HGNC: HGNC:2190
Homologene: 22421
Tns2
Name: tensin 2
Synonyms: nep, nph, Tenc1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 209039
VEGA: 15
Homologene: 37077
Sec14l2
Name: SEC14-like lipid binding 2
Synonyms: 1300013M05Rik, tap, Spf
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 67815
Homologene: 8245
Fat3
Name: FAT atypical cadherin 3
Synonyms: LOC234973, LOC382129, D430038H04Rik, 9430076A06Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 270120
VEGA: 9
Homologene: 82252
Spta1
Name: spectrin alpha, erythrocytic 1
Synonyms: Spna-1, erythroid, ihj, Spna1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 20739
Homologene: 74460
Chia1
Name: chitinase, acidic 1
Synonyms: AMCase, YNL, 2200003E03Rik, Chia
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 81600
Homologene: 75168
Dpyd
Name: dihydropyrimidine dehydrogenase
Synonyms: DPD, E330028L06Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99586
HGNC: HGNC:3012
Homologene: 85
Fbn2
Name: fibrillin 2
Synonyms: sy, Sne, Fib-2
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 14119
VEGA: 18
HGNC: HGNC:3604
Homologene: 1515
Dnah9
Name: dynein, axonemal, heavy chain 9
Synonyms: D11Ertd686e, Dnahc9
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237806
HGNC: HGNC:2953
Homologene: 20357
Taar2
Name: trace amine-associated receptor 2
Synonyms: Gpr58
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 209512
HGNC: HGNC:4514
Homologene: 110760
Myh3
Name: myosin, heavy polypeptide 3, skeletal muscle, embryonic
Synonyms: MyHC-emb, Myhs-e, Myhse
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17883
HGNC: HGNC:7573
Homologene: 20553
Adam34l
Name: a disintegrin and metallopeptidase domain 34 like
Synonyms: Gm5346
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 384813
Homologene: 78104
Tom1l1
Name: target of myb1-like 1 (chicken)
Synonyms: 2310045L10Rik, Srcasm
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 71943
Homologene: 38055
Rasal3
Name: RAS protein activator like 3
Synonyms: A430107D22Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 320484
Homologene: 18901
Frmd4a
Name: FERM domain containing 4A
Synonyms: C230040M21Rik, 2700017I06Rik, Gm13190
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 209630
Homologene: 9971
Bsn
Name: bassoon
Synonyms: presynaptic cytomatrix protein
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 12217
HGNC: HGNC:1117
Homologene: 31161
Rev3l
Name: REV3 like, DNA directed polymerase zeta catalytic subunit
Synonyms: Sez4, Rev
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 19714
HGNC: HGNC:9968
Homologene: 48147
Cog2
Name: component of oligomeric golgi complex 2
Synonyms: 1190002B08Rik, 2700012E02Rik, Cog2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 76332
HGNC: HGNC:6546
Homologene: 7206
Slc4a10
Name: solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
Synonyms: NCBE
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 94229
Homologene: 23340
Adam2
Name: a disintegrin and metallopeptidase domain 2
Synonyms: Ph30-beta, Ftnb, fertilin beta
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 11495
VEGA: 14
HGNC: HGNC:198
Homologene: 1127
Acte1
Name: actin, epsilon 1
Synonyms: LOC244239, Gm498
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 102636989
Homologene: 131918
Map7d1
Name: MAP7 domain containing 1
Synonyms: Parcc1, Rprc1, Mtap7d1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 245877
Homologene: 17009
Synj1
Name: synaptojanin 1
Synonyms: A930006D20Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 104015
Homologene: 48252
Kif21b
Name: kinesin family member 21B
Synonyms: N-5 kinesin, 2610511N21Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16565
Homologene: 56868
Mc2r
Name: melanocortin 2 receptor
Synonyms: adrenocorticotropic hormone receptor, Acthr
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 17200
VEGA: 18
HGNC: HGNC:6930
Homologene: 444
Usp45
Name: ubiquitin specific petidase 45
Synonyms: 3110003C05Rik, Gcap7, 4930550B20Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 77593
Homologene: 17674
Aldh3b3
Name: aldehyde dehydrogenase 3 family, member B3
Synonyms: 1700055N04Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 73458
HGNC: HGNC:411
Homologene: 133295
Vmn1r209
Name: vomeronasal 1 receptor 209
Synonyms: Gm11315
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 432736
Homologene: 110880
Acd
Name: adrenocortical dysplasia
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 497652
Homologene: 23391
Or4d5
Name: olfactory receptor family 4 subfamily D member 5
Synonyms: GA_x6K02T2PVTD-33799484-33798540, MOR239-6, Olfr984
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258601
VEGA: 9
Homologene: 17314
Traf5
Name: TNF receptor-associated factor 5
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 22033
Homologene: 27079
Trpv6
Name: transient receptor potential cation channel, subfamily V, member 6
Synonyms: CaT1, Cac, CAT, Ecac2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 64177
Homologene: 56812
R3hdml
Name: R3H domain containing-like
Synonyms: OTTMUSG00000001070
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 100043899
Homologene: 45608
Chil4
Name: chitinase-like 4
Synonyms: Ym2, Chi3l4
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 104183
Homologene: 74931
Cmtr2
Name: cap methyltransferase 2
Synonyms: C730036L12Rik, Ftsjd1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234728
Homologene: 10144
Glyatl3
Name: glycine-N-acyltransferase-like 3
Synonyms: Gm5683
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 435528
VEGA: 17
Homologene: 19824
Mutyh
Name: mutY DNA glycosylase
Synonyms: 5730495A01Rik, Myh, Mutyhbeta, Mutyhalpha, Mutyhc, Mutyhb, Mutyha
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 70603
HGNC: HGNC:7527
Homologene: 8156
Zfp51
Name: zinc finger protein 51
Synonyms: zfec12, Zfp-51
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 22709
VEGA: 17
Homologene: 134003
Chchd2
Name: coiled-coil-helix-coiled-coil-helix domain containing 2
Synonyms: Etohi6
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 14004
Homologene: 49449
Cyct
Name: cytochrome c, testis
Synonyms: T-Cc
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 13067
Homologene: 129551
Pcdha12
Name: protocadherin alpha 12
Synonyms: Cnr5, Crnr5, Pcdha13
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 192164
HGNC: HGNC:8667
Homologene: 135870
Trgv3
Name: T cell receptor gamma, variable 3
Synonyms: vgamma3, Tcrg-V3
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 21637
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to A, chromosome 1 at 63,536,972 bp (GRCm38)
  • A to T, chromosome 1 at 105,687,352 bp (GRCm38)
  • A to T, chromosome 1 at 136,174,062 bp (GRCm38)
  • T to C, chromosome 1 at 165,399,667 bp (GRCm38)
  • T to C, chromosome 1 at 174,208,412 bp (GRCm38)
  • T to C, chromosome 1 at 192,062,733 bp (GRCm38)
  • A to G, chromosome 2 at 4,604,233 bp (GRCm38)
  • T to C, chromosome 2 at 62,253,318 bp (GRCm38)
  • T to A, chromosome 2 at 76,354,113 bp (GRCm38)
  • T to C, chromosome 2 at 163,502,452 bp (GRCm38)
  • T to C, chromosome 3 at 89,347,483 bp (GRCm38)
  • A to G, chromosome 3 at 106,128,675 bp (GRCm38)
  • A to T, chromosome 3 at 106,204,066 bp (GRCm38)
  • G to A, chromosome 3 at 119,314,911 bp (GRCm38)
  • A to G, chromosome 3 at 123,505,400 bp (GRCm38)
  • A to C, chromosome 3 at 138,065,422 bp (GRCm38)
  • A to C, chromosome 4 at 18,887,647 bp (GRCm38)
  • A to T, chromosome 4 at 21,824,998 bp (GRCm38)
  • T to A, chromosome 4 at 116,816,877 bp (GRCm38)
  • A to G, chromosome 4 at 126,234,231 bp (GRCm38)
  • C to A, chromosome 4 at 143,572,744 bp (GRCm38)
  • A to G, chromosome 5 at 76,216,824 bp (GRCm38)
  • A to G, chromosome 5 at 91,402,656 bp (GRCm38)
  • A to T, chromosome 5 at 129,887,213 bp (GRCm38)
  • A to G, chromosome 6 at 41,625,444 bp (GRCm38)
  • T to C, chromosome 6 at 54,699,556 bp (GRCm38)
  • A to T, chromosome 7 at 92,657,326 bp (GRCm38)
  • G to T, chromosome 7 at 143,881,165 bp (GRCm38)
  • A to C, chromosome 8 at 43,626,267 bp (GRCm38)
  • A to C, chromosome 8 at 94,334,997 bp (GRCm38)
  • T to C, chromosome 8 at 105,698,882 bp (GRCm38)
  • C to T, chromosome 8 at 110,223,080 bp (GRCm38)
  • G to A, chromosome 8 at 122,487,093 bp (GRCm38)
  • A to T, chromosome 8 at 124,527,098 bp (GRCm38)
  • T to C, chromosome 9 at 16,021,423 bp (GRCm38)
  • G to A, chromosome 9 at 22,058,025 bp (GRCm38)
  • T to C, chromosome 9 at 40,101,155 bp (GRCm38)
  • A to G, chromosome 9 at 108,115,794 bp (GRCm38)
  • T to A, chromosome 9 at 114,706,008 bp (GRCm38)
  • T to C, chromosome 10 at 12,678,731 bp (GRCm38)
  • T to C, chromosome 10 at 23,941,339 bp (GRCm38)
  • C to T, chromosome 10 at 39,817,153 bp (GRCm38)
  • T to C, chromosome 10 at 61,867,469 bp (GRCm38)
  • A to T, chromosome 10 at 119,985,549 bp (GRCm38)
  • T to C, chromosome 10 at 128,731,177 bp (GRCm38)
  • A to G, chromosome 11 at 4,118,665 bp (GRCm38)
  • T to A, chromosome 11 at 66,085,474 bp (GRCm38)
  • A to G, chromosome 11 at 67,093,571 bp (GRCm38)
  • TTGCTGCTGCTGCTGCTG to TTGCTGCTGCTGCTG, chromosome 11 at 90,649,822 bp (GRCm38)
  • T to C, chromosome 12 at 40,636,156 bp (GRCm38)
  • A to G, chromosome 13 at 19,243,271 bp (GRCm38)
  • T to A, chromosome 13 at 22,805,902 bp (GRCm38)
  • A to G, chromosome 14 at 56,019,410 bp (GRCm38)
  • A to T, chromosome 14 at 66,050,472 bp (GRCm38)
  • C to A, chromosome 15 at 102,110,561 bp (GRCm38)
  • T to C, chromosome 16 at 90,988,207 bp (GRCm38)
  • T to A, chromosome 17 at 21,464,471 bp (GRCm38)
  • T to A, chromosome 17 at 24,550,477 bp (GRCm38)
  • TTGGACCTGAGTGGA to TTGGA, chromosome 17 at 32,393,528 bp (GRCm38)
  • C to T, chromosome 17 at 40,912,662 bp (GRCm38)
  • A to G, chromosome 18 at 37,020,821 bp (GRCm38)
  • A to G, chromosome 18 at 58,209,784 bp (GRCm38)
  • A to T, chromosome 18 at 68,407,565 bp (GRCm38)
  • T to C, chromosome 19 at 3,963,882 bp (GRCm38)
  • T to C, chromosome 19 at 52,264,820 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9307 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069122-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.