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Strain Name:
C57BL/6J-MtgxR9321Btlr/Mmmh
Stock Number:
069133-MU
Citation ID:
RRID:MMRRC_069133-MU
Other Names:
R9321 (G1)
Major Collection:

Strain Information

Nos1
Name: nitric oxide synthase 1, neuronal
Synonyms: nNOS, bNOS, Nos-1, NO, 2310005C01Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 18125
HGNC: HGNC:7872
Homologene: 37327
Akap10
Name: A kinase anchor protein 10
Synonyms: D-AKAP2, 1500031L16Rik, B130049N18Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 56697
HGNC: HGNC:368
Homologene: 32452
Pdzd2
Name: PDZ domain containing 2
Synonyms: 4930537L06Rik, LOC223364, A930022H17Rik, Pdzk3, Gm21706
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 68070
Homologene: 23393
Nfya
Name: nuclear transcription factor-Y alpha
Synonyms: Sez10, Cbf-b
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 18044
HGNC: HGNC:7804
Homologene: 32114
Eif2ak4
Name: eukaryotic translation initiation factor 2 alpha kinase 4
Synonyms: GCN2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 27103
Homologene: 40891
Txlna
Name: taxilin alpha
Synonyms: 2600010N21Rik, Txln, IL14
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 109658
Homologene: 14062
Mark4
Name: MAP/microtubule affinity regulating kinase 4
Synonyms: Markl1, 2410090P21Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 232944
Homologene: 57146
Nars1
Name: asparaginyl-tRNA synthetase 1
Synonyms: ASNRS, Nars
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 70223
VEGA: 18
HGNC: HGNC:7643
Homologene: 68404
Zfp592
Name: zinc finger protein 592
Synonyms: A730014M16Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233410
Homologene: 8759
Tpd52l1
Name: tumor protein D52-like 1
Synonyms: D53
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 21987
VEGA: 10
Homologene: 2468
Enpp5
Name: ectonucleotide pyrophosphatase/phosphodiesterase 5
Synonyms: D17Abb1e
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 83965
Homologene: 23313
Rad52
Name: RAD52 homolog, DNA repair protein
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 19365
HGNC: HGNC:9824
Homologene: 31118
Mtx3
Name: metaxin 3
Synonyms: LOC382793, 4930470O13Rik, Gm6514
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 382793
VEGA: 13
Homologene: 46611
Nptx1
Name: neuronal pentraxin 1
Synonyms: Np1, D11Bwg1004e
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18164
HGNC: HGNC:7952
Homologene: 1891
Adam15
Name: ADAM metallopeptidase domain 15
Synonyms: metargidin, MDC15
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 11490
HGNC: HGNC:193
Homologene: 2829
Abca13
Name: ATP-binding cassette, sub-family A member 13
Synonyms: A930002G16Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 268379
Homologene: 27991
Lig1
Name: ligase I, DNA, ATP-dependent
Synonyms: mLigI, LigI
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 16881
HGNC: HGNC:6598
Homologene: 197
Dnah2
Name: dynein, axonemal, heavy chain 2
Synonyms: D330014H01Rik, 2900022L05Rik, Dnhd3, Dnahc2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 327954
HGNC: HGNC:2948
Homologene: 72110
Ush2a
Name: usherin
Synonyms: MUSH2A, A930011D15Rik, LOC381317, LOC269160, A930037M10Rik, Ushrn, Ush2a
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 22283
Homologene: 66151
Tubgcp6
Name: tubulin, gamma complex component 6
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 328580
Homologene: 32477
Carmil3
Name: capping protein regulator and myosin 1 linker 3
Synonyms: Lrrc16b
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 268747
VEGA: 14
Homologene: 74564
Vmn1r76
Name: vomeronasal 1 receptor 76
Synonyms: V1rg4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 171239
Slx4
Name: SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
Synonyms: D16Bwg1016e, Btbd12
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 52864
Homologene: 23770
Or6d13
Name: olfactory receptor family 6 subfamily D member 13
Synonyms: GA_x54KRFPKN04-58174409-58175392, MOR119-3, Olfr213
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 258020
Homologene: 74186
Ap3b2
Name: adaptor-related protein complex 3, beta 2 subunit
Synonyms: Naptb, beta3B
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 11775
HGNC: HGNC:567
Homologene: 55837
Or11g27
Name: olfactory receptor family 11 subfamily G member 27
Synonyms: GA_x6K02T2N6FY-3870-3385, GA_x6K02T2N6FY-2320-2039, GA_x6K02T2PMLR-6243196-6244132, MOR106-8P, MOR106-14, Olfr265, Olfr743-ps1, Olfr264, Olfr743
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 219019
Homologene: 74163
Adam34
Name: a disintegrin and metallopeptidase domain 34
Synonyms: testase 4
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 252866
Homologene: 78104
Tas2r123
Name: taste receptor, type 2, member 123
Synonyms: T2R23, Tas2r23, STC 9-2, mGR23, mt2r55
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 353167
Homologene: 45450
Dclre1a
Name: DNA cross-link repair 1A
Synonyms: mSNM1, SNM1, 2810043H12Rik, SMN1a
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 55947
Homologene: 8920
Tdrd1
Name: tudor domain containing 1
Synonyms: MTR-1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 83561
Homologene: 12850
Plekha6
Name: pleckstrin homology domain containing, family A member 6
Synonyms: Pepp3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 240753
Homologene: 135779
Prorp
Name: protein only RNase P catalytic subunit
Synonyms: 1110008L16Rik, Mrpp3
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 66132
Homologene: 45935
Mroh5
Name: maestro heat-like repeat family member 5
Synonyms: LOC268816, Gm628
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 268816
Tcaf1
Name: TRPM8 channel-associated factor 1
Synonyms: A230020K05Rik, 2810407D09Rik, 3321401G04Rik, Fam115a
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 77574
Homologene: 8815
Spem1
Name: spermatid maturation 1
Synonyms: 1700095G12Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 74288
Homologene: 45717
Gm1110
Name: predicted gene 1110
Synonyms: LOC382064
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 382064
VEGA: 9
Homologene: 78608
Or13c25
Name: olfactory receptor family 13 subfamily C member 25
Synonyms: GA_x6K02T2N78B-7084885-7085844, MOR262-7, Olfr272
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 258836
Homologene: 17409
Btbd2
Name: BTB domain containing 2
Synonyms: 2610037C03Rik, 4930512K17Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 208198
Homologene: 32365
Kcnb2
Name: potassium voltage gated channel, Shab-related subfamily, member 2
Synonyms: Kv2.2, 9630047L19Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 98741
HGNC: HGNC:6232
Homologene: 31263
Itpripl1
Name: inositol 1,4,5-triphosphate receptor interacting protein-like 1
Synonyms: 1700041B20Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 73338
Homologene: 77641
Irag1
Name: inositol 1,4,5-triphosphate receptor associated 1
Synonyms: Ris1, Mrvi1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 17540
HGNC: HGNC:7237
Homologene: 4425
Gm57858
Name: gene model 57858
Synonyms: Ccdc144b
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 241943
Homologene: 87263
Slc22a16
Name: solute carrier family 22 (organic cation transporter), member 16
Synonyms: FLIPT2, OKB1, OCT6, CT2, 4921504E14Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 70840
Homologene: 41957
Or5j3
Name: olfactory receptor family 5 subfamily J member 3
Synonyms: GA_x6K02T2Q125-47777498-47778436, MOR172-1, Olfr1052
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 259012
Homologene: 79679
Nlrp4e
Name: NLR family, pyrin domain containing 4E
Synonyms: Nalp-epsilon, Nalp4e, 4930406H16Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 446099
Homologene: 75315
Or4k44
Name: olfactory receptor family 4 subfamily K member 44
Synonyms: GA_x6K02T2Q125-72589785-72588847, MOR248-7, Olfr1294
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258887
Homologene: 74216
Acvr2b
Name: activin receptor IIB
Synonyms: ActRIIB
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 11481
VEGA: 9
HGNC: HGNC:174
Homologene: 863
H2-Ab1
Name: histocompatibility 2, class II antigen A, beta 1
Synonyms: A beta, Abeta, H-2Ab, Ia-2, Ia2, H2-Ab, IAb, I-Ab, I-Abeta, Rmcs1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 14961
Homologene: 1603
Aifm2
Name: apoptosis-inducing factor, mitochondrion-associated 2
Synonyms: PRG3, D730001I10Rik, 5430437E11Rik, Amid
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 71361
Homologene: 6862
Spg7
Name: SPG7, paraplegin matrix AAA peptidase subunit
Synonyms: paraplegin, Cmar, spastic paraplegia 7 homolog (human)
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234847
Homologene: 31133
Crtc3
Name: CREB regulated transcription coactivator 3
Synonyms: 6332415K15Rik, 2610312F20Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 70461
Homologene: 11248
Nme5
Name: NME/NM23 family member 5
Synonyms: 1700019D05Rik, Nm23-M5, non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase)
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 75533
HGNC: HGNC:7853
Homologene: 2628
Tmem179
Name: transmembrane protein 179
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 104885
VEGA: 12
Homologene: 16809
Timd2
Name: T cell immunoglobulin and mucin domain containing 2
Synonyms: Tim2, TIM-2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 171284
Homologene: 82236
Hmx2
Name: H6 homeobox 2
Synonyms: Nkx5-2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 15372
HGNC: HGNC:5018
Homologene: 24625
Zfp606
Name: zinc finger protein 606
Synonyms: 2410022M24Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 67370
Homologene: 23514
Nicn1
Name: nicolin 1
Synonyms: 1500032A17Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 66257
Homologene: 11936
Or13m2-ps1
Name: olfactory receptor family 13 subfamily M member 2, pseudogene 1
Synonyms: GA_x6K02T2P3E9-4759141-4758206, MOR257-6, Olfr451-ps1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 258017
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • G to A, chromosome 1 at 15,709,569 bp (GRCm38)
  • A to G, chromosome 1 at 133,281,811 bp (GRCm38)
  • A to T, chromosome 1 at 188,356,951 bp (GRCm38)
  • A to T, chromosome 2 at 86,297,953 bp (GRCm38)
  • A to G, chromosome 2 at 111,538,089 bp (GRCm38)
  • G to A, chromosome 2 at 118,462,317 bp (GRCm38)
  • T to C, chromosome 2 at 127,142,080 bp (GRCm38)
  • A to T, chromosome 3 at 36,018,990 bp (GRCm38)
  • T to A, chromosome 3 at 89,347,487 bp (GRCm38)
  • G to T, chromosome 4 at 52,911,314 bp (GRCm38)
  • T to A, chromosome 4 at 129,634,453 bp (GRCm38)
  • T to C, chromosome 5 at 74,620,330 bp (GRCm38)
  • G to C, chromosome 5 at 117,879,337 bp (GRCm38)
  • T to C, chromosome 6 at 42,679,356 bp (GRCm38)
  • T to A, chromosome 6 at 42,800,858 bp (GRCm38)
  • T to C, chromosome 6 at 116,541,409 bp (GRCm38)
  • T to C, chromosome 6 at 119,913,008 bp (GRCm38)
  • A to T, chromosome 6 at 132,848,132 bp (GRCm38)
  • A to T, chromosome 7 at 11,931,167 bp (GRCm38)
  • A to G, chromosome 7 at 12,492,683 bp (GRCm38)
  • T to C, chromosome 7 at 13,301,009 bp (GRCm38)
  • G to T, chromosome 7 at 19,436,976 bp (GRCm38)
  • C to G, chromosome 7 at 23,321,330 bp (GRCm38)
  • G to T, chromosome 7 at 25,530,664 bp (GRCm38)
  • G to A, chromosome 7 at 80,609,902 bp (GRCm38)
  • C to T, chromosome 7 at 81,041,478 bp (GRCm38)
  • T to C, chromosome 7 at 81,464,504 bp (GRCm38)
  • A to G, chromosome 7 at 110,925,327 bp (GRCm38)
  • A to G, chromosome 7 at 131,555,591 bp (GRCm38)
  • C to T, chromosome 8 at 15,122,464 bp (GRCm38)
  • C to T, chromosome 8 at 43,652,206 bp (GRCm38)
  • C to A, chromosome 8 at 123,076,949 bp (GRCm38)
  • T to A, chromosome 9 at 26,920,595 bp (GRCm38)
  • C to T, chromosome 9 at 108,294,509 bp (GRCm38)
  • T to C, chromosome 9 at 119,428,285 bp (GRCm38)
  • T to C, chromosome 10 at 31,338,193 bp (GRCm38)
  • T to A, chromosome 10 at 40,574,051 bp (GRCm38)
  • C to T, chromosome 10 at 61,735,631 bp (GRCm38)
  • A to C, chromosome 10 at 80,647,841 bp (GRCm38)
  • A to G, chromosome 11 at 9,510,475 bp (GRCm38)
  • T to C, chromosome 11 at 46,687,089 bp (GRCm38)
  • A to G, chromosome 11 at 61,900,409 bp (GRCm38)
  • C to T, chromosome 11 at 69,448,113 bp (GRCm38)
  • T to C, chromosome 11 at 69,821,835 bp (GRCm38)
  • G to A, chromosome 11 at 77,842,544 bp (GRCm38)
  • A to G, chromosome 11 at 119,547,552 bp (GRCm38)
  • A to G, chromosome 12 at 55,304,649 bp (GRCm38)
  • G to T, chromosome 12 at 112,510,956 bp (GRCm38)
  • T to A, chromosome 13 at 92,847,589 bp (GRCm38)
  • C to A, chromosome 14 at 34,544,142 bp (GRCm38)
  • G to A, chromosome 14 at 50,534,014 bp (GRCm38)
  • G to T, chromosome 14 at 55,503,968 bp (GRCm38)
  • T to C, chromosome 15 at 12,385,937 bp (GRCm38)
  • A to G, chromosome 15 at 73,789,264 bp (GRCm38)
  • T to C, chromosome 15 at 89,107,983 bp (GRCm38)
  • A to G, chromosome 16 at 3,986,790 bp (GRCm38)
  • T to C, chromosome 17 at 34,267,995 bp (GRCm38)
  • T to C, chromosome 17 at 44,082,798 bp (GRCm38)
  • A to T, chromosome 17 at 48,400,466 bp (GRCm38)
  • T to G, chromosome 18 at 34,571,544 bp (GRCm38)
  • C to T, chromosome 18 at 64,504,879 bp (GRCm38)
  • A to G, chromosome 19 at 56,542,668 bp (GRCm38)
  • T to C, chromosome 19 at 56,860,335 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9321 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069133-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.