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Strain Name:
C57BL/6J-MtgxR9354Btlr/Mmmh
Stock Number:
069164-MU
Citation ID:
RRID:MMRRC_069164-MU
Other Names:
R9354 (G1)
Major Collection:

Strain Information

Itga8
Name: integrin alpha 8
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241226
HGNC: HGNC:6144
Homologene: 37396
Cemip2
Name: cell migration inducing hyaluronidase 2
Synonyms: 3110012M15Rik, Tmem2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 83921
VEGA: 19
Homologene: 75008
Jmjd1c
Name: jumonji domain containing 1C
Synonyms: TRIP8, 5430433L24Rik, D630035I23Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 108829
Homologene: 3129
Gid4
Name: GID complex subunit 4, VID24 homolog
Synonyms: 4933439F18Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 66771
Homologene: 5971
Wnk1
Name: WNK lysine deficient protein kinase 1
Synonyms: 6430573H23Rik, Prkwnk1, EG406236, Hsn2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232341
Homologene: 14253
Rps6ka1
Name: ribosomal protein S6 kinase polypeptide 1
Synonyms: Rsk1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 20111
Homologene: 55703
Map4
Name: microtubule-associated protein 4
Synonyms: MAP 4, Mtap4
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 17758
HGNC: HGNC:6862
Homologene: 1780
Rapgef6
Name: Rap guanine nucleotide exchange factor (GEF) 6
Synonyms: PDZ-GEF2, RA-GEF-2, Pdzgef2, C030018K18Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 192786
Homologene: 22968
Birc6
Name: baculoviral IAP repeat-containing 6
Synonyms: apollon, Bruce, A430032G04Rik, D630005A10Rik, A430040A19Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 12211
Homologene: 7248
Ralgapb
Name: Ral GTPase activating protein, beta subunit (non-catalytic)
Synonyms: B230339M05Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228850
Homologene: 10666
Cep68
Name: centrosomal protein 68
Synonyms: 6030463E10Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216543
Homologene: 65235
Cenpf
Name: centromere protein F
Synonyms: 6530404A22Rik, Lek1, mitosin
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 108000
HGNC: HGNC:1857
Homologene: 22969
Slf2
Name: SMC5-SMC6 complex localization factor 2
Synonyms: 6030443O07Rik, Fam178a
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226151
VEGA: 19
Homologene: 23077
Gper1
Name: G protein-coupled estrogen receptor 1
Synonyms: 6330420K13Rik, Ceprl, GPCR-Br, CMKRL2, FEG-1, Gper, Gpr30
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 76854
HGNC: HGNC:4485
Homologene: 15855
Muc2
Name: mucin 2
Synonyms: 2010015E03Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 17831
HGNC: HGNC:7512
Homologene: 136755
Prune2
Name: prune homolog 2
Synonyms: 6330414G02Rik, A330102H22Rik, A230083H22Rik, Olfaxin
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 353211
VEGA: 19
Homologene: 18939
Chpf2
Name: chondroitin polymerizing factor 2
Synonyms: 2010209O12Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100910
Homologene: 14763
Ctsl
Name: cathepsin L
Synonyms: major excreted protein, MEP, Cat L, 1190035F06Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 13039
VEGA: 13
Homologene: 76699
Usp42
Name: ubiquitin specific peptidase 42
Synonyms: 3110031A07Rik, 2410140K03Rik, D5Ertd591e, A630018G05Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 76800
Homologene: 35425
Ppwd1
Name: peptidylprolyl isomerase domain and WD repeat containing 1
Synonyms: A330090G21Rik, 4632422M10Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 238831
VEGA: 13
Homologene: 9099
Lcorl
Name: ligand dependent nuclear receptor corepressor-like
Synonyms: Mlr1, A830039H10Rik, Gm3414
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100041576
Homologene: 82325
Vat1
Name: vesicle amine transport 1
Synonyms: VAT-1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 26949
Homologene: 36200
Rorc
Name: RAR-related orphan receptor gamma
Synonyms: thymus orphan receptor, Thor, RORgamma
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 19885
Homologene: 21051
Myh6
Name: myosin, heavy polypeptide 6, cardiac muscle, alpha
Synonyms: alpha myosin, Myhc-a, alpha cardiac MHC, cardiomyopathy, hypertrophic 1, Myhca, A830009F23Rik, alpha-MHC, alphaMHC
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 17888
HGNC: HGNC:7576
Homologene: 124414
Tex15
Name: testis expressed gene 15 meiosis and synapsis associated
Synonyms: 2210014E14Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 104271
Homologene: 12837
Trpm3
Name: transient receptor potential cation channel, subfamily M, member 3
Synonyms: B930001P07Rik, 6330504P12Rik, MLSN2, melastatin 2, LTRPC3
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226025
VEGA: 19
Homologene: 62287
Vmn2r57
Name: vomeronasal 2, receptor 57
Synonyms: EG269902
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 269902
Homologene: 104832
Sdk2
Name: sidekick cell adhesion molecule 2
Synonyms: 5330435L01Rik, 4632412F08Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237979
Homologene: 10406
Acsl1
Name: acyl-CoA synthetase long-chain family member 1
Synonyms: Acas1, Facl2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 14081
HGNC: HGNC:3569
Homologene: 37561
Prss59
Name: serine protease 59
Synonyms: Tryx5, 1700074P13Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 73481
Homologene: 49905
Naip1
Name: NLR family, apoptosis inhibitory protein 1
Synonyms: D13Lsd1, Naip, Birc1a
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 17940
VEGA: 13
HGNC: HGNC:7634
Homologene: 113589
Grhpr
Name: glyoxylate reductase/hydroxypyruvate reductase
Synonyms: 6430629L09Rik, 1110059D05Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 76238
HGNC: HGNC:4570
Homologene: 49088
Itgad
Name: integrin, alpha D
Synonyms: Cd11d
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 381924
HGNC: HGNC:6146
Homologene: 56919
Dis3l
Name: DIS3 like exosome 3'-5' exoribonuclease
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 213550
Homologene: 15797
Pde8a
Name: phosphodiesterase 8A
Synonyms: Pde8
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18584
HGNC: HGNC:8793
Homologene: 1957
Agap2
Name: ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
Synonyms: Centg1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216439
VEGA: 10
Homologene: 86815
Spag17
Name: sperm associated antigen 17
Synonyms: 4931427F14Rik, PF6
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 74362
Homologene: 52601
Espnl
Name: espin-like
Synonyms: LOC227357
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 227357
Homologene: 77795
Caskin2
Name: CASK-interacting protein 2
Synonyms: 1600028L06Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 140721
Homologene: 32485
Apol7c
Name: apolipoprotein L 7c
Synonyms: 2210421G13Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 108956
VEGA: 15
HGNC: HGNC:619
Homologene: 40940
Ccdc30
Name: coiled-coil domain containing 30
Synonyms: 1700111D19Rik, 4930445I03Rik, 1700001O02Rik, 1700041C02Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 73332
Homologene: 137391
Slc26a4
Name: solute carrier family 26, member 4
Synonyms: Pds, pendrin
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 23985
VEGA: 12
HGNC: HGNC:8818
Homologene: 20132
Sema5a
Name: sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
Synonyms: M-Sema D, semF, Semaf, 9130201M22Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 20356
VEGA: 15
Homologene: 2949
Lilra6
Name: leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
Synonyms: 7M1, Pira3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18726
Homologene: 134028
Klhl33
Name: kelch-like 33
Synonyms: EG546611
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 546611
VEGA: 14
Homologene: 52385
Zswim5
Name: zinc finger SWIM-type containing 5
Synonyms: 4933426E21Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 74464
Homologene: 18958
Vmn1r85
Name: vomeronasal 1 receptor 85
Synonyms: V1rj3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 252909
Homologene: 74338
Gbp9
Name: guanylate-binding protein 9
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 236573
Homologene: 128731
Ankrd44
Name: ankyrin repeat domain 44
Synonyms: E130014H08Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 329154
Homologene: 27547
Trim38
Name: tripartite motif-containing 38
Synonyms: LOC214158
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 214158
Homologene: 48427
Marchf5
Name: membrane associated ring-CH-type finger 5
Synonyms: 2310008I22Rik, E130202O05Rik, 1810015H18Rik, MARCH-V, 2700055A20Rik, Rnf153, 5730499H23Rik, MITOL, March5
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 69104
Homologene: 9862
Gpr146
Name: G protein-coupled receptor 146
Synonyms: PGR8
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 80290
Homologene: 36472
Or52b3
Name: olfactory receptor family 52 subfamily B member 3
Synonyms: GA_x6K02T2PBJ9-5274337-5275287, MOR31-3, Olfr549
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259105
Homologene: 86245
Gstm6
Name: glutathione S-transferase, mu 6
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 14867
HGNC: HGNC:4632
Homologene: 117950
Pick1
Name: protein interacting with C kinase 1
Synonyms: Prkcabp
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 18693
HGNC: HGNC:9394
Homologene: 7470
Ly6c1
Name: lymphocyte antigen 6 family member C1
Synonyms: Ly-6C, Ly6c
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 17067
Homologene: 113718
Igfbpl1
Name: insulin-like growth factor binding protein-like 1
Synonyms: 2810011G06Rik, IGFBP-like protein, 2810453O06Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 75426
Homologene: 10292
Pcdhgc4
Name: protocadherin gamma subfamily C, 4
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93707
HGNC: HGNC:8717
Homologene: 110932
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to T, chromosome 1 at 54,648,279 bp (GRCm38)
  • A to T, chromosome 1 at 91,344,601 bp (GRCm38)
  • G to A, chromosome 1 at 189,646,917 bp (GRCm38)
  • T to C, chromosome 2 at 12,232,857 bp (GRCm38)
  • A to G, chromosome 2 at 68,606,529 bp (GRCm38)
  • A to G, chromosome 2 at 158,437,393 bp (GRCm38)
  • A to T, chromosome 3 at 94,372,863 bp (GRCm38)
  • A to G, chromosome 3 at 100,027,589 bp (GRCm38)
  • A to T, chromosome 3 at 107,942,702 bp (GRCm38)
  • G to T, chromosome 4 at 44,981,465 bp (GRCm38)
  • A to T, chromosome 4 at 45,816,348 bp (GRCm38)
  • G to A, chromosome 4 at 116,987,035 bp (GRCm38)
  • G to T, chromosome 4 at 119,373,653 bp (GRCm38)
  • A to C, chromosome 4 at 133,867,121 bp (GRCm38)
  • T to C, chromosome 5 at 24,591,394 bp (GRCm38)
  • T to A, chromosome 5 at 45,733,626 bp (GRCm38)
  • T to A, chromosome 5 at 105,084,959 bp (GRCm38)
  • A to G, chromosome 5 at 139,392,611 bp (GRCm38)
  • G to A, chromosome 5 at 139,426,274 bp (GRCm38)
  • A to G, chromosome 5 at 143,715,272 bp (GRCm38)
  • A to G, chromosome 6 at 40,928,539 bp (GRCm38)
  • C to T, chromosome 6 at 119,965,699 bp (GRCm38)
  • A to G, chromosome 7 at 3,911,629 bp (GRCm38)
  • T to A, chromosome 7 at 13,084,798 bp (GRCm38)
  • T to C, chromosome 7 at 41,400,239 bp (GRCm38)
  • C to T, chromosome 7 at 81,332,871 bp (GRCm38)
  • G to A, chromosome 7 at 102,555,190 bp (GRCm38)
  • C to A, chromosome 7 at 128,185,974 bp (GRCm38)
  • A to G, chromosome 7 at 141,753,420 bp (GRCm38)
  • C to G, chromosome 8 at 33,573,316 bp (GRCm38)
  • T to G, chromosome 8 at 46,513,716 bp (GRCm38)
  • T to C, chromosome 9 at 64,314,640 bp (GRCm38)
  • A to G, chromosome 9 at 110,068,779 bp (GRCm38)
  • T to C, chromosome 10 at 67,224,096 bp (GRCm38)
  • A to C, chromosome 10 at 127,087,235 bp (GRCm38)
  • T to C, chromosome 11 at 20,238,569 bp (GRCm38)
  • G to T, chromosome 11 at 54,619,923 bp (GRCm38)
  • G to T, chromosome 11 at 60,417,792 bp (GRCm38)
  • A to C, chromosome 11 at 101,460,615 bp (GRCm38)
  • T to C, chromosome 11 at 113,834,931 bp (GRCm38)
  • G to A, chromosome 11 at 115,802,642 bp (GRCm38)
  • A to T, chromosome 12 at 31,535,256 bp (GRCm38)
  • A to T, chromosome 13 at 23,785,892 bp (GRCm38)
  • A to T, chromosome 13 at 64,369,036 bp (GRCm38)
  • A to G, chromosome 13 at 100,427,486 bp (GRCm38)
  • C to T, chromosome 13 at 104,205,572 bp (GRCm38)
  • T to A, chromosome 14 at 7,818,411 bp (GRCm38)
  • T to C, chromosome 14 at 50,892,928 bp (GRCm38)
  • T to A, chromosome 14 at 54,963,535 bp (GRCm38)
  • T to A, chromosome 15 at 32,562,756 bp (GRCm38)
  • T to A, chromosome 15 at 75,044,622 bp (GRCm38)
  • C to T, chromosome 15 at 77,525,912 bp (GRCm38)
  • T to C, chromosome 15 at 79,239,648 bp (GRCm38)
  • A to T, chromosome 15 at 97,796,888 bp (GRCm38)
  • A to G, chromosome 17 at 74,614,406 bp (GRCm38)
  • A to G, chromosome 18 at 37,816,587 bp (GRCm38)
  • A to G, chromosome 19 at 17,122,622 bp (GRCm38)
  • A to G, chromosome 19 at 21,802,025 bp (GRCm38)
  • G to A, chromosome 19 at 22,448,332 bp (GRCm38)
  • G to T, chromosome 19 at 37,207,865 bp (GRCm38)
  • T to A, chromosome 19 at 44,948,032 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9354 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069164-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.