Strain Name:
C57BL/6J-MtgxR9376Btlr/Mmmh
Stock Number:
069184-MU
Citation ID:
RRID:MMRRC_069184-MU
Other Names:
R9376 (G1)
Major Collection:

Strain Information

Ppp5c
Name: protein phosphatase 5, catalytic subunit
Synonyms: ANP receptor, PP5
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 19060
HGNC: HGNC:9322
Homologene: 4550
Sephs1
Name: selenophosphate synthetase 1
Synonyms: SPS1, 1110046B24Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 109079
Homologene: 56558
Lrp5
Name: low density lipoprotein receptor-related protein 5
Synonyms: LRP7, LR3
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 16973
Homologene: 1746
Zc3h13
Name: zinc finger CCCH type containing 13
Synonyms: 4930570G11Rik, C87618, 3110050K21Rik, 2600010B19Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 67302
VEGA: 14
Ptpn11
Name: protein tyrosine phosphatase, non-receptor type 11
Synonyms: 2700084A17Rik, Syp, SHP-2, SH-PTP2, PTP1D, PTP2C, Shp2, SH2 domain-containing protein tyrosine phosphatase-2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 19247
HGNC: HGNC:9644
Homologene: 2122
Nup214
Name: nucleoporin 214
Synonyms: CAN, D2H9S46E
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227720
HGNC: HGNC:8064
Homologene: 38008
Prrc2a
Name: proline-rich coiled-coil 2A
Synonyms: 3110039B05Rik, Bat-2, Bat2, G2, D17H6S51E, Wbp12
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 53761
Homologene: 10567
Itpr1
Name: inositol 1,4,5-trisphosphate receptor 1
Synonyms: Pcp-1, Pcp1, IP3R1, InsP3R type I, P400, Ip3r, opt, wblo, Itpr-1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16438
HGNC: HGNC:6180
Homologene: 1673
Pno1
Name: partner of NOB1 homolog
Synonyms: 1810003N24Rik, Imi3, Emi3, expressed during mesenchymal induction 3
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 66249
Homologene: 6961
Clpb
Name: ClpB caseinolytic peptidase B
Synonyms: Skd3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 20480
Homologene: 32067
Kdm3b
Name: KDM3B lysine (K)-specific demethylase 3B
Synonyms: JHDM2B, Jmjd1b, 5830462I21Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 277250
VEGA: 18
HGNC: HGNC:1337
Homologene: 41145
Dnah7a
Name: dynein, axonemal, heavy chain 7A
Synonyms: Dnahc7, LOC381341, Dnahc7a
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 627872
Homologene: 41287
Rbm33
Name: RNA binding motif protein 33
Synonyms: 3200001K10Rik, 6430512A10Rik, Prr8
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 381626
Homologene: 137386
Palld
Name: palladin, cytoskeletal associated protein
Synonyms: 2410003B16Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 72333
Homologene: 75052
Terf2ip
Name: telomeric repeat binding factor 2, interacting protein
Synonyms: Rap1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 57321
Homologene: 10357
Erich1
Name: glutamate rich 1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234086
Homologene: 19271
Atp2a3
Name: ATPase, Ca++ transporting, ubiquitous
Synonyms: Serca3
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 53313
HGNC: HGNC:813
Homologene: 69131
Tcaim
Name: T cell activation inhibitor, mitochondrial
Synonyms: LOC382117, D9Ertd402e
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 382117
Homologene: 45481
Zfhx4
Name: zinc finger homeodomain 4
Synonyms: Zfh4, Zfh-4, C130041O22Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 80892
Homologene: 23477
Lama2
Name: laminin, alpha 2
Synonyms: merosin, mer
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 16773
HGNC: HGNC:6482
Homologene: 37306
Hydin
Name: HYDIN, axonemal central pair apparatus protein
Synonyms: 4930545D19Rik, hyrh, hy-3, hy3, 1700034M11Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244653
Homologene: 52118
Abcb4
Name: ATP-binding cassette, sub-family B member 4
Synonyms: Mdr2, Pgy-2, mdr-2, Pgy2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 18670
HGNC: HGNC:45
Homologene: 136368
Dchs1
Name: dachsous cadherin related 1
Synonyms: C130033F22Rik, 3110041P15Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233651
Homologene: 2771
Dennd4a
Name: DENN domain containing 4A
Synonyms: F730015K02Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 102442
VEGA: 9
Homologene: 55933
Nalcn
Name: sodium leak channel, non-selective
Synonyms: Vgcnl1, A530023G15Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 338370
VEGA: 14
Homologene: 21832
Col6a3
Name: collagen, type VI, alpha 3
Synonyms: Col6a-3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12835
HGNC: HGNC:2213
Homologene: 37917
Scube3
Name: signal peptide, CUB domain, EGF-like 3
Synonyms: D030038I21Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 268935
Homologene: 65059
Ache
Name: acetylcholinesterase
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 11423
HGNC: HGNC:108
Homologene: 543
Cntn4
Name: contactin 4
Synonyms: BIG-2A, Axcam
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 269784
HGNC: HGNC:2174
Homologene: 14257
Tshz2
Name: teashirt zinc finger family member 2
Synonyms: 2900073F20Rik, Tsh2, Mtsh2, Sdccag33l, Zfp218, teashirt2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228911
Homologene: 35258
Tnfrsf18
Name: tumor necrosis factor receptor superfamily, member 18
Synonyms: Gitr
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 21936
Homologene: 48270
Trim10
Name: tripartite motif-containing 10
Synonyms: Rnf9, Herf1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 19824
Homologene: 4932
Itga1
Name: integrin alpha 1
Synonyms: Vla1, CD49A, E130012M19Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 109700
VEGA: 13
HGNC: HGNC:6134
Homologene: 57137
Abca14
Name: ATP-binding cassette, sub-family A member 14
Synonyms: 1700110B15Rik, 4930539G24Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 67928
Homologene: 86128
Cntln
Name: centlein, centrosomal protein
Synonyms: B430108F07Rik, D530005L17Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 338349
Homologene: 9805
Ctdnep1
Name: CTD nuclear envelope phosphatase 1
Synonyms: Dullard, 2610507E10Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 67181
Homologene: 9100
Dao
Name: D-amino acid oxidase
Synonyms: Dao1, Dao-1, DAO
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 13142
HGNC: HGNC:2671
Homologene: 37553
Gpaa1
Name: GPI anchor attachment protein 1
Synonyms: mGAA1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 14731
HGNC: HGNC:4446
Homologene: 37852
Ifi205
Name: interferon activated gene 205
Synonyms: D3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226695
Homologene: 115929
Or1x6
Name: olfactory receptor family 1 subfamily X member 6
Synonyms: Olfr1375, GA_x6K02T2QP88-4389999-4389056, MOR126-2, Olfr1375-ps1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258509
Ano3
Name: anoctamin 3
Synonyms: B230324K02Rik, Tmem16c
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228432
Homologene: 57147
Itgax
Name: integrin alpha X
Synonyms: Cd11c, CD11C (p150) alpha polypeptide, CR4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 16411
HGNC: HGNC:6152
Homologene: 55493
Oas1f
Name: 2'-5' oligoadenylate synthetase 1F
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 243262
HGNC: HGNC:8086
Homologene: 86720
Or5p58
Name: olfactory receptor family 5 subfamily P member 58
Synonyms: GA_x6K02T2PBJ9-10424354-10423383, Olfr482, MOR204-14
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258728
Homologene: 133604
Krt80
Name: keratin 80
Synonyms: 1200016G03Rik, Kb20, 2310041I20Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 74127
VEGA: 15
Homologene: 66610
Cyp2c67
Name: cytochrome P450, family 2, subfamily c, polypeptide 67
Synonyms: C730004C24Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 545288
Homologene: 74936
Gm17732
Name: predicted gene, 17732
Type: Gene
Species: Mouse
Chromosome: 18
Or2t46
Name: olfactory receptor family 2 subfamily T member 46
Synonyms: MOR275-11_p, MOR275-5, Olfr325, GA_x6K02T2NKPP-844642-843680
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258261
Homologene: 133015
Ankrd13d
Name: ankyrin repeat domain 13 family, member D
Synonyms: 0710001P18Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 68423
Homologene: 27612
Or51f1e
Name: olfactory receptor family 51 subfamily F member 1E
Synonyms: Olfr585, MOR14-4, GA_x6K02T2PBJ9-5809085-5810035
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259091
Homologene: 133721
Mtmr11
Name: myotubularin related protein 11
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 194126
Homologene: 82382
Epn1
Name: epsin 1
Synonyms: Ibp1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 13854
Homologene: 32172
Gpr65
Name: G-protein coupled receptor 65
Synonyms: Gpcr25, Dig1, TDAG8
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 14744
VEGA: 12
HGNC: HGNC:4517
Homologene: 2675
Or2t43
Name: olfactory receptor family 2 subfamily T member 43
Synonyms: Olfr327-ps1, GA_x6K02T00261-652-347, GA_x6K02T2NKPP-858022-858862, MOR275-10_p, Olfr224, MOR275-3
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258198
Homologene: 133015
Runx1t1
Name: RUNX1 translocation partner 1
Synonyms: Cbfa2t1h, ETO, MTG8
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 12395
HGNC: HGNC:1535
Homologene: 3801
Cldn11
Name: claudin 11
Synonyms: Otm, oligodendrocyte-specific protein, Osp
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 18417
HGNC: HGNC:8514
Homologene: 4093
Triqk
Name: triple QxxK/R motif containing
Synonyms: Gm11818, Triqk
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 208820
Homologene: 90150
Pigyl
Name: phosphatidylinositol glycan anchor biosynthesis, class Y-like
Synonyms: 1810008A14Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 66268
Homologene: 134660
Map6d1
Name: MAP6 domain containing 1
Synonyms: A330066I15Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 208158
VEGA: 16
Homologene: 11763
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to A, chromosome 1 at 53,528,899 bp (GRCm38)
  • C to T, chromosome 1 at 90,781,801 bp (GRCm38)
  • T to C, chromosome 1 at 174,026,655 bp (GRCm38)
  • T to A, chromosome 2 at 4,905,658 bp (GRCm38)
  • T to C, chromosome 2 at 32,034,232 bp (GRCm38)
  • A to G, chromosome 2 at 110,666,437 bp (GRCm38)
  • G to A, chromosome 2 at 169,884,093 bp (GRCm38)
  • A to G, chromosome 3 at 5,241,773 bp (GRCm38)
  • A to G, chromosome 3 at 5,400,335 bp (GRCm38)
  • T to C, chromosome 3 at 31,163,261 bp (GRCm38)
  • T to A, chromosome 3 at 96,165,055 bp (GRCm38)
  • A to G, chromosome 4 at 12,962,987 bp (GRCm38)
  • A to G, chromosome 4 at 13,865,225 bp (GRCm38)
  • A to G, chromosome 4 at 84,957,021 bp (GRCm38)
  • G to T, chromosome 4 at 156,027,991 bp (GRCm38)
  • A to T, chromosome 5 at 8,958,988 bp (GRCm38)
  • A to G, chromosome 5 at 28,339,166 bp (GRCm38)
  • T to A, chromosome 5 at 114,009,840 bp (GRCm38)
  • C to A, chromosome 5 at 120,848,180 bp (GRCm38)
  • C to A, chromosome 5 at 121,144,618 bp (GRCm38)
  • A to C, chromosome 5 at 137,290,763 bp (GRCm38)
  • T to C, chromosome 6 at 106,662,630 bp (GRCm38)
  • T to A, chromosome 6 at 108,349,677 bp (GRCm38)
  • A to T, chromosome 7 at 5,083,721 bp (GRCm38)
  • A to T, chromosome 7 at 17,009,924 bp (GRCm38)
  • A to T, chromosome 7 at 101,711,418 bp (GRCm38)
  • A to T, chromosome 7 at 103,097,764 bp (GRCm38)
  • A to G, chromosome 7 at 105,765,774 bp (GRCm38)
  • A to T, chromosome 7 at 108,095,264 bp (GRCm38)
  • T to A, chromosome 7 at 120,294,215 bp (GRCm38)
  • T to C, chromosome 7 at 128,148,763 bp (GRCm38)
  • A to G, chromosome 8 at 14,030,719 bp (GRCm38)
  • C to T, chromosome 8 at 61,516,657 bp (GRCm38)
  • T to C, chromosome 8 at 110,398,063 bp (GRCm38)
  • C to T, chromosome 8 at 112,011,882 bp (GRCm38)
  • A to G, chromosome 8 at 112,017,896 bp (GRCm38)
  • A to G, chromosome 9 at 22,158,028 bp (GRCm38)
  • A to T, chromosome 9 at 64,912,692 bp (GRCm38)
  • T to C, chromosome 9 at 122,826,930 bp (GRCm38)
  • T to C, chromosome 10 at 27,118,624 bp (GRCm38)
  • A to T, chromosome 11 at 17,208,791 bp (GRCm38)
  • T to A, chromosome 11 at 51,048,835 bp (GRCm38)
  • T to A, chromosome 11 at 58,566,857 bp (GRCm38)
  • T to C, chromosome 11 at 58,581,810 bp (GRCm38)
  • T to C, chromosome 11 at 69,984,768 bp (GRCm38)
  • T to C, chromosome 11 at 72,972,464 bp (GRCm38)
  • T to A, chromosome 12 at 98,275,264 bp (GRCm38)
  • T to C, chromosome 13 at 114,970,576 bp (GRCm38)
  • G to A, chromosome 14 at 75,323,688 bp (GRCm38)
  • G to A, chromosome 14 at 123,278,301 bp (GRCm38)
  • C to A, chromosome 15 at 76,334,626 bp (GRCm38)
  • T to A, chromosome 15 at 101,350,097 bp (GRCm38)
  • T to C, chromosome 16 at 20,241,183 bp (GRCm38)
  • G to T, chromosome 17 at 28,164,696 bp (GRCm38)
  • A to T, chromosome 17 at 35,150,622 bp (GRCm38)
  • A to T, chromosome 17 at 36,873,276 bp (GRCm38)
  • T to C, chromosome 18 at 34,837,665 bp (GRCm38)
  • G to T, chromosome 18 at 62,662,865 bp (GRCm38)
  • T to C, chromosome 19 at 3,620,286 bp (GRCm38)
  • A to T, chromosome 19 at 4,282,222 bp (GRCm38)
  • A to T, chromosome 19 at 39,638,734 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9376 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069184-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.