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Strain Name:
C57BL/6J-MtgxR9390Btlr/Mmmh
Stock Number:
069196-MU
Citation ID:
RRID:MMRRC_069196-MU
Other Names:
R9390 (G1)
Major Collection:

Strain Information

Fga
Name: fibrinogen alpha chain
Synonyms: Fib, ENSMUSG00000059807
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 14161
HGNC: HGNC:3661
Homologene: 428
Trp53
Name: transformation related protein 53
Synonyms: p53, p44
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 22059
Homologene: 460
Il4
Name: interleukin 4
Synonyms: Il-4
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16189
HGNC: HGNC:6014
Homologene: 491
Mga
Name: MAX gene associated
Synonyms: Mga, Mad5, C130042M01Rik, D030062C11Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 29808
Homologene: 49351
Ints14
Name: integrator complex subunit 14
Synonyms: 2010321M09Rik, Vwa9
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 69882
VEGA: 9
Homologene: 12774
Pds5a
Name: PDS5 cohesin associated factor A
Synonyms: E230024D05Rik, 9030416H16Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 71521
Homologene: 22877
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • C to T, chromosome 1 at 90,939,366 bp (GRCm38)
  • T to C, chromosome 2 at 30,330,765 bp (GRCm38)
  • A to G, chromosome 2 at 31,808,737 bp (GRCm38)
  • T to G, chromosome 2 at 32,767,183 bp (GRCm38)
  • A to T, chromosome 2 at 52,175,145 bp (GRCm38)
  • A to T, chromosome 2 at 87,093,046 bp (GRCm38)
  • T to C, chromosome 2 at 89,943,225 bp (GRCm38)
  • A to T, chromosome 2 at 119,523,699 bp (GRCm38)
  • C to T, chromosome 2 at 119,963,851 bp (GRCm38)
  • C to T, chromosome 2 at 151,970,196 bp (GRCm38)
  • A to T, chromosome 3 at 83,033,303 bp (GRCm38)
  • T to C, chromosome 3 at 105,986,567 bp (GRCm38)
  • A to G, chromosome 3 at 142,503,022 bp (GRCm38)
  • T to C, chromosome 4 at 9,635,927 bp (GRCm38)
  • A to G, chromosome 4 at 13,865,932 bp (GRCm38)
  • T to A, chromosome 4 at 46,005,416 bp (GRCm38)
  • T to G, chromosome 4 at 138,258,170 bp (GRCm38)
  • T to C, chromosome 5 at 21,748,812 bp (GRCm38)
  • C to T, chromosome 5 at 29,434,768 bp (GRCm38)
  • A to G, chromosome 5 at 31,040,459 bp (GRCm38)
  • G to A, chromosome 5 at 62,818,561 bp (GRCm38)
  • G to T, chromosome 5 at 65,375,701 bp (GRCm38)
  • G to T, chromosome 5 at 65,666,257 bp (GRCm38)
  • T to A, chromosome 5 at 123,180,731 bp (GRCm38)
  • C to T, chromosome 6 at 57,625,970 bp (GRCm38)
  • C to T, chromosome 6 at 119,320,987 bp (GRCm38)
  • T to C, chromosome 6 at 124,580,377 bp (GRCm38)
  • A to T, chromosome 6 at 149,183,485 bp (GRCm38)
  • T to C, chromosome 7 at 62,419,540 bp (GRCm38)
  • T to C, chromosome 8 at 81,770,893 bp (GRCm38)
  • A to G, chromosome 9 at 64,984,032 bp (GRCm38)
  • T to A, chromosome 9 at 119,917,179 bp (GRCm38)
  • G to T, chromosome 10 at 79,481,488 bp (GRCm38)
  • C to T, chromosome 10 at 127,173,370 bp (GRCm38)
  • A to G, chromosome 10 at 129,660,069 bp (GRCm38)
  • G to A, chromosome 11 at 23,706,937 bp (GRCm38)
  • C to A, chromosome 11 at 53,000,275 bp (GRCm38)
  • C to T, chromosome 11 at 53,614,010 bp (GRCm38)
  • G to A, chromosome 11 at 59,327,766 bp (GRCm38)
  • A to T, chromosome 11 at 69,587,568 bp (GRCm38)
  • C to T, chromosome 11 at 119,915,462 bp (GRCm38)
  • A to G, chromosome 13 at 22,278,365 bp (GRCm38)
  • A to C, chromosome 13 at 46,687,166 bp (GRCm38)
  • A to G, chromosome 13 at 49,530,316 bp (GRCm38)
  • A to T, chromosome 13 at 67,591,063 bp (GRCm38)
  • C to T, chromosome 13 at 67,593,895 bp (GRCm38)
  • A to G, chromosome 14 at 21,848,799 bp (GRCm38)
  • A to G, chromosome 16 at 12,267,544 bp (GRCm38)
  • A to T, chromosome 16 at 91,056,208 bp (GRCm38)
  • T to A, chromosome 16 at 94,673,471 bp (GRCm38)
  • T to A, chromosome 17 at 24,604,850 bp (GRCm38)
  • T to C, chromosome 17 at 71,750,988 bp (GRCm38)
  • T to C, chromosome 18 at 37,309,728 bp (GRCm38)
  • G to A, chromosome 18 at 53,706,912 bp (GRCm38)
  • G to A, chromosome 18 at 58,671,278 bp (GRCm38)
  • A to T, chromosome 19 at 6,112,695 bp (GRCm38)
  • A to G, chromosome 19 at 55,202,175 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain GQC Summary
Gene Specific Genotyping:

To request gene-specific and other genotyping services for a strain, please contact the distribution MMRRC Center for more information.

Background Genetic Quality:

The MMRRC has developed a Genetic Quality Control pipeline using the MiniMUGA array to provide additional information to identify and validate genetic backgrounds of MMRRC strains. For more information on whether genetic background data is available, please contact MMRRC_GeneticQC@med.unc.edu. Note: that MiniMUGA genetic background data is not available on all strains, but can be ordered if desired.

Suggested Control Mice
Littermates of all relevant genotypes.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9390 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.


Disclaimer: If MMRRC Strain Genetic Quality Control (GQC; based on MiniMUGA genotyping and analysis) has been completed for this strain, the information might differ from the genetic background information provided by the submitter. MiniMUGA genetic analysis is done on a strain’s tissue samples taken when archived by or ordered from the assigned MMRRC Center.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069196-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.