Strain Name:
C57BL/6J-MtgxR9390Btlr/Mmmh
Stock Number:
069196-MU
Citation ID:
RRID:MMRRC_069196-MU
Other Names:
R9390 (G1)
Major Collection:

Strain Information

Fga
Name: fibrinogen alpha chain
Synonyms: ENSMUSG00000059807, Fib
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 14161
HGNC: HGNC:3661
Homologene: 428
Trp53
Name: transformation related protein 53
Synonyms: p53, p44
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 22059
Homologene: 460
Il4
Name: interleukin 4
Synonyms: Il-4
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16189
HGNC: HGNC:6014
Homologene: 491
Mga
Name: MAX gene associated
Synonyms: Mga, D030062C11Rik, C130042M01Rik, Mad5
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 29808
Homologene: 49351
Nup188
Name: nucleoporin 188
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227699
Homologene: 45683
Ints14
Name: integrator complex subunit 14
Synonyms: 2010321M09Rik, Vwa9
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 69882
VEGA: 9
Homologene: 12774
Pds5a
Name: PDS5 cohesin associated factor A
Synonyms: 9030416H16Rik, E230024D05Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 71521
Homologene: 22877
Wdr48
Name: WD repeat domain 48
Synonyms: Uaf1, 8430408H12Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 67561
VEGA: 9
Homologene: 10830
Dyrk1a
Name: dual-specificity tyrosine phosphorylation regulated kinase 1a
Synonyms: Mnbh, 2310043O08Rik, D16Ertd493e, Dyrk, D16Ertd272e
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 13548
HGNC: HGNC:3091
Homologene: 55576
Exd1
Name: exonuclease 3'-5' domain containing 1
Synonyms: 4932702D22Rik, Exdl1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241624
Homologene: 17627
Pus10
Name: pseudouridylate synthase 10
Synonyms: Ccdc139, 2810013G11Rik, 4933435A13Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 74467
Homologene: 12566
Cep120
Name: centrosomal protein 120
Synonyms: Ccdc100
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225523
VEGA: 18
Homologene: 27415
Isoc1
Name: isochorismatase domain containing 1
Synonyms: 2610034N03Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 66307
VEGA: 18
Homologene: 9361
Asph
Name: aspartate-beta-hydroxylase
Synonyms: aspartyl beta-hydroxylase, calsequestrin-binding protein, BAH, jumbug, 3110001L23Rik, junctate, cI-37, Junctin, 2310005F16Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 65973
HGNC: HGNC:757
Homologene: 20910
Nup153
Name: nucleoporin 153
Synonyms: B130015D15Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218210
HGNC: HGNC:8062
Homologene: 68442
Tsc2
Name: TSC complex subunit 2
Synonyms: tuberous sclerosis 2, tuberin, Nafld
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 22084
VEGA: 17
Homologene: 462
Pmpcb
Name: peptidase (mitochondrial processing) beta
Synonyms: MPPP52, MPP11, 3110004O18Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 73078
HGNC: HGNC:9119
Homologene: 3160
Mlph
Name: melanophilin
Synonyms: D1Wsu84e, Slac-2a
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 171531
Homologene: 11465
Klb
Name: klotho beta
Synonyms: betaKlotho
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 83379
Homologene: 12820
Pcdhb4
Name: protocadherin beta 4
Synonyms: PcdhbD, Pcdhb5A
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93875
HGNC: HGNC:8690
Homologene: 62176
Ttc16
Name: tetratricopeptide repeat domain 16
Synonyms: 1200002K10Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 338348
Homologene: 17011
Neb
Name: nebulin
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17996
HGNC: HGNC:7720
Homologene: 136285
Gbp5
Name: guanylate binding protein 5
Synonyms: 5330409J06Rik, Gbp5a
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229898
Homologene: 14183
Or6c210
Name: olfactory receptor family 6 subfamily C member 210
Synonyms: Olfr800, GA_x6K02T2PULF-11338429-11339364, MOR114-7
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 258541
Homologene: 27203
Chmp6
Name: charged multivesicular body protein 6
Synonyms: 2400004G01Rik, chromatin modifying protein 6
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 208092
Homologene: 11607
Gucy2g
Name: guanylate cyclase 2g
Synonyms: 2410077I05Rik, GC-G
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 73707
Homologene: 44544
Tdrd7
Name: tudor domain containing 7
Synonyms: 5730495N10Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100121
Homologene: 8618
Ecm2
Name: extracellular matrix protein 2, female organ and adipocyte specific
Synonyms: 9030618O22Rik, tenonectin
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 407800
VEGA: 13
HGNC: HGNC:3154
Homologene: 1064
Vmn1r195
Name: vomeronasal 1 receptor 195
Synonyms: V1ri6
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 171257
Homologene: 110880
Hpd
Name: 4-hydroxyphenylpyruvic acid dioxygenase
Synonyms: Laf, Fla, Flp, Hppd
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 15445
HGNC: HGNC:5147
Homologene: 1620
Inpp4b
Name: inositol polyphosphate-4-phosphatase, type II
Synonyms: E130107I17Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234515
HGNC: HGNC:6075
Homologene: 20832
Vmn2r83
Name: vomeronasal 2, receptor 83
Synonyms: EG625029
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 625029
Homologene: 83669
Dthd1
Name: death domain containing 1
Synonyms: Gm17384
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100322896
Homologene: 123510
Naaladl1
Name: N-acetylated alpha-linked acidic dipeptidase-like 1
Synonyms: LOC381204
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 381204
Homologene: 21124
Epcip
Name: exosomal polycystin 1 interacting protein
Synonyms: 4932438H23Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 74387
HGNC: HGNC:1305
Homologene: 49594
Amn1
Name: antagonist of mitotic exit network 1
Synonyms: C730024G19Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232566
Homologene: 45811
Shisa9
Name: shisa family member 9
Synonyms: 2700045P11Rik, CKAMP44
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 72555
Homologene: 109462
Qrfp
Name: pyroglutamylated RFamide peptide
Synonyms: QRFP, P518
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227717
Homologene: 52341
Herc6
Name: hect domain and RLD 6
Synonyms: 1700121D12Rik, CEB1, Herc5, 4930427L17Rik, 2510038N07Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 67138
Homologene: 70768
Ovgp1
Name: oviductal glycoprotein 1
Synonyms: oviductin, OGP, MOGP, muc9, mucin 9, Chit5
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 12659
HGNC: HGNC:8524
Homologene: 74442
Fam110a
Name: family with sequence similarity 110, member A
Synonyms: 1700008J10Rik, 5430432M24Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 73847
Homologene: 12862
Or4c12
Name: olfactory receptor family 4 subfamily C member 12
Synonyms: Olfr1259, GA_x6K02T2Q125-51376062-51375133, MOR232-9
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258338
Homologene: 128115
Pcare
Name: photoreceptor cilium actin regulator
Synonyms: BC027072
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 225004
VEGA: 17
Homologene: 19792
Lrtm2
Name: leucine-rich repeats and transmembrane domains 2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 211187
Homologene: 65244
Fstl4
Name: follistatin-like 4
Synonyms: SPIG1, B230374F23Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 320027
Homologene: 18543
Or5aq6
Name: olfactory receptor family 5 subfamily AQ member 6
Synonyms: GA_x6K02T2Q125-48586461-48585523, MOR172-5, Olfr1109
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258762
Homologene: 86672
Mkrn3
Name: makorin, ring finger protein, 3
Synonyms: D7H15S9-1, Zfp127
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 22652
HGNC: HGNC:7114
Homologene: 4143
Sh2d5
Name: SH2 domain containing 5
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230863
Homologene: 20002
Nom1
Name: nucleolar protein with MIF4G domain 1
Synonyms: Gm1040, D5Kng1, LOC381627
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 433864
Homologene: 39776
Slc5a6
Name: solute carrier family 5 (sodium-dependent vitamin transporter), member 6
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 330064
Homologene: 23277
Slc26a10
Name: solute carrier family 26, member 10
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216441
VEGA: 10
Homologene: 66953
Comtd1
Name: catechol-O-methyltransferase domain containing 1
Synonyms: MT773, 1810030M08Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 69156
Homologene: 41703
Wnt9a
Name: wingless-type MMTV integration site family, member 9A
Synonyms: Wnt14
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216795
Homologene: 20722
Runx1t1
Name: RUNX1 translocation partner 1
Synonyms: Cbfa2t1h, ETO, MTG8
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 12395
HGNC: HGNC:1535
Homologene: 3801
C1rb
Name: complement component 1, r subcomponent B
Synonyms: Gm8551, mC1rB
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 667277
HGNC: HGNC:1246
Homologene: 1313
Zfp729b
Name: zinc finger protein 729b
Synonyms: AA987161
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 100416706
Homologene: 133713
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • C to T, chromosome 1 at 90,939,366 bp (GRCm38)
  • T to C, chromosome 2 at 30,330,765 bp (GRCm38)
  • A to G, chromosome 2 at 31,808,737 bp (GRCm38)
  • T to G, chromosome 2 at 32,767,183 bp (GRCm38)
  • A to T, chromosome 2 at 52,175,145 bp (GRCm38)
  • A to T, chromosome 2 at 87,093,046 bp (GRCm38)
  • T to C, chromosome 2 at 89,943,225 bp (GRCm38)
  • A to T, chromosome 2 at 119,523,699 bp (GRCm38)
  • C to T, chromosome 2 at 119,963,851 bp (GRCm38)
  • C to T, chromosome 2 at 151,970,196 bp (GRCm38)
  • A to T, chromosome 3 at 83,033,303 bp (GRCm38)
  • T to C, chromosome 3 at 105,986,567 bp (GRCm38)
  • A to G, chromosome 3 at 142,503,022 bp (GRCm38)
  • T to C, chromosome 4 at 9,635,927 bp (GRCm38)
  • A to G, chromosome 4 at 13,865,932 bp (GRCm38)
  • T to A, chromosome 4 at 46,005,416 bp (GRCm38)
  • T to G, chromosome 4 at 138,258,170 bp (GRCm38)
  • T to C, chromosome 5 at 21,748,812 bp (GRCm38)
  • C to T, chromosome 5 at 29,434,768 bp (GRCm38)
  • A to G, chromosome 5 at 31,040,459 bp (GRCm38)
  • G to A, chromosome 5 at 62,818,561 bp (GRCm38)
  • G to T, chromosome 5 at 65,375,701 bp (GRCm38)
  • G to T, chromosome 5 at 65,666,257 bp (GRCm38)
  • T to A, chromosome 5 at 123,180,731 bp (GRCm38)
  • C to T, chromosome 6 at 57,625,970 bp (GRCm38)
  • C to T, chromosome 6 at 119,320,987 bp (GRCm38)
  • T to C, chromosome 6 at 124,580,377 bp (GRCm38)
  • A to T, chromosome 6 at 149,183,485 bp (GRCm38)
  • T to C, chromosome 7 at 62,419,540 bp (GRCm38)
  • T to C, chromosome 8 at 81,770,893 bp (GRCm38)
  • A to G, chromosome 9 at 64,984,032 bp (GRCm38)
  • T to A, chromosome 9 at 119,917,179 bp (GRCm38)
  • G to T, chromosome 10 at 79,481,488 bp (GRCm38)
  • C to T, chromosome 10 at 127,173,370 bp (GRCm38)
  • A to G, chromosome 10 at 129,660,069 bp (GRCm38)
  • G to A, chromosome 11 at 23,706,937 bp (GRCm38)
  • C to A, chromosome 11 at 53,000,275 bp (GRCm38)
  • C to T, chromosome 11 at 53,614,010 bp (GRCm38)
  • G to A, chromosome 11 at 59,327,766 bp (GRCm38)
  • A to T, chromosome 11 at 69,587,568 bp (GRCm38)
  • C to T, chromosome 11 at 119,915,462 bp (GRCm38)
  • A to G, chromosome 13 at 22,278,365 bp (GRCm38)
  • A to C, chromosome 13 at 46,687,166 bp (GRCm38)
  • A to G, chromosome 13 at 49,530,316 bp (GRCm38)
  • A to T, chromosome 13 at 67,591,063 bp (GRCm38)
  • C to T, chromosome 13 at 67,593,895 bp (GRCm38)
  • A to G, chromosome 14 at 21,848,799 bp (GRCm38)
  • A to G, chromosome 16 at 12,267,544 bp (GRCm38)
  • A to T, chromosome 16 at 91,056,208 bp (GRCm38)
  • T to A, chromosome 16 at 94,673,471 bp (GRCm38)
  • T to A, chromosome 17 at 24,604,850 bp (GRCm38)
  • T to C, chromosome 17 at 71,750,988 bp (GRCm38)
  • T to C, chromosome 18 at 37,309,728 bp (GRCm38)
  • G to A, chromosome 18 at 53,706,912 bp (GRCm38)
  • G to A, chromosome 18 at 58,671,278 bp (GRCm38)
  • A to T, chromosome 19 at 6,112,695 bp (GRCm38)
  • A to G, chromosome 19 at 55,202,175 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9390 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069196-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.