Strain Name:
C57BL/6J-MtgxR9464Btlr/Mmmh
Stock Number:
069267-MU
Citation ID:
RRID:MMRRC_069267-MU
Other Names:
R9464 (G1)
Major Collection:

Strain Information

Kifc3
Name: kinesin family member C3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 16582
HGNC: HGNC:6326
Homologene: 124421
Uchl3
Name: ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 50933
VEGA: 14
Homologene: 4377
Crybg3
Name: beta-gamma crystallin domain containing 3
Synonyms: Gm9581
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224273
Homologene: 28544
Tesk2
Name: testis-specific kinase 2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230661
Homologene: 5188
Vps13c
Name: vacuolar protein sorting 13C
Synonyms: C230055H22Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 320528
VEGA: 9
Homologene: 41188
Anapc5
Name: anaphase-promoting complex subunit 5
Synonyms: 2510006G12Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 59008
Homologene: 41118
Rnf40
Name: ring finger protein 40
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233900
Homologene: 8856
Trrap
Name: transformation/transcription domain-associated protein
Synonyms: transactivation/transformation-domain associated protein
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100683
Homologene: 39246
Fancc
Name: Fanconi anemia, complementation group C
Synonyms: Facc
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 14088
HGNC: HGNC:3584
Homologene: 109
Zgrf1
Name: zinc finger, GRF-type containing 1
Synonyms: 4930422G04Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 71643
Homologene: 34708
Tlk1
Name: tousled-like kinase 1
Synonyms: 4930545J15Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228012
Homologene: 130657
Abi2
Name: abl interactor 2
Synonyms: 8430425M24Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 329165
Homologene: 4209
Ryr2
Name: ryanodine receptor 2, cardiac
Synonyms: 9330127I20Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 20191
VEGA: 13
Homologene: 37423
Abhd5
Name: abhydrolase domain containing 5
Synonyms: IECN5, 2010002J10Rik, NCIE2, 1300003D03Rik, CGI-58
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 67469
Homologene: 41088
Ppp1r15a
Name: protein phosphatase 1, regulatory subunit 15A
Synonyms: Gadd34, Myd116
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 17872
Homologene: 8639
Tph2
Name: tryptophan hydroxylase 2
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216343
Homologene: 27831
Map2
Name: microtubule-associated protein 2
Synonyms: MAP-2, G1-397-34, repro4, Mtap2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 17756
HGNC: HGNC:6839
Homologene: 1779
Psmd4
Name: proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
Synonyms: Mcb1, multiubiquitin-chain-binding protein, angiocidin, Af1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 19185
HGNC: HGNC:9561
Homologene: 55691
Dnajc18
Name: DnaJ heat shock protein family (Hsp40) member C18
Synonyms: 2700075B01Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 76594
VEGA: 18
Homologene: 23692
N4bp1
Name: NEDD4 binding protein 1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 80750
Homologene: 23703
Zfp473
Name: zinc finger protein 473
Synonyms: D030014N22Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243963
Homologene: 18698
Fbxo46
Name: F-box protein 46
Synonyms: Fbxo34l, 20D7-FC4, 4932704E22Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243867
Homologene: 18467
Lonrf1
Name: LON peptidase N-terminal domain and ring finger 1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244421
Homologene: 34980
Tmem207
Name: transmembrane protein 207
Synonyms: LOC224058, 100043057
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 100043057
VEGA: 16
Homologene: 52611
Srcap
Name: Snf2-related CREBBP activator protein
Synonyms: D030022P06Rik, F630004O05Rik, B930091H02Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 100043597
Homologene: 38213
Hmcn1
Name: hemicentin 1
Synonyms: LOC240793, EG545370
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 545370
Homologene: 23741
Pclo
Name: piccolo (presynaptic cytomatrix protein)
Synonyms: Pico, Acz
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 26875
Homologene: 69111
Nek10
Name: NIMA (never in mitosis gene a)- related kinase 10
Synonyms: LOC238944
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 674895
Homologene: 130947
Abca4
Name: ATP-binding cassette, sub-family A member 4
Synonyms: Rim protein, RmP, D430003I15Rik, Abc10
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 11304
HGNC: HGNC:34
Homologene: 298
Pkhd1l1
Name: polycystic kidney and hepatic disease 1-like 1
Synonyms: D86 mRNA, PKHDL1, fibrocystin L
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 192190
Homologene: 16332
Myo3a
Name: myosin IIIA
Synonyms: 9030416P08Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 667663
HGNC: HGNC:7601
Homologene: 49486
Rnf213
Name: ring finger protein 213
Synonyms: D11Ertd759e
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 672511
Homologene: 45439
Adcy3
Name: adenylate cyclase 3
Synonyms: AC3, ACIII
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 104111
HGNC: HGNC:234
Homologene: 2978
Vwa3a
Name: von Willebrand factor A domain containing 3A
Synonyms: E030013G06Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233813
Homologene: 18607
Nckap5
Name: NCK-associated protein 5
Synonyms: E030049G20Rik, D130011D22Rik, LOC380609
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 210356
Homologene: 35542
Vipr1
Name: vasoactive intestinal peptide receptor 1
Synonyms: VIP-R1, VIP receptor subtype 1, VPAC1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 22354
Homologene: 3399
Adcy2
Name: adenylate cyclase 2
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 210044
VEGA: 13
HGNC: HGNC:233
Homologene: 75133
Ttc21b
Name: tetratricopeptide repeat domain 21B
Synonyms: Thm1, 2410066K11Rik, line 158, aln
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 73668
Homologene: 57006
Slc30a4
Name: solute carrier family 30 (zinc transporter), member 4
Synonyms: Znt4
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22785
Homologene: 74984
Dthd1
Name: death domain containing 1
Synonyms: Gm17384
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100322896
Homologene: 123510
Mug2
Name: murinoglobulin 2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 17837
HGNC: HGNC:9750
Homologene: 136663
Sp100
Name: nuclear antigen Sp100
Synonyms: A430075G10Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 20684
Homologene: 86761
Card14
Name: caspase recruitment domain family, member 14
Synonyms: Bimp2, CARMA2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 170720
Homologene: 11469
Tgfbrap1
Name: transforming growth factor, beta receptor associated protein 1
Synonyms: 3110018K12Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 73122
Homologene: 3141
Zfp956
Name: zinc finger protein 956
Synonyms: AI894139
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 101197
Homologene: 128449
Vmn2r117
Name: vomeronasal 2, receptor 117
Synonyms: EG619788, V2Rp6
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 619788
Homologene: 86604
Plaat5
Name: phospholipase A and acyltransferase 5
Synonyms: iNAT, 1700086E08Rik, 1700055A14Rik, 4921526K24Rik, Hrasls5
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 66727
Homologene: 12019
Gcnt4
Name: glucosaminyl (N-acetyl) transferase 4, core 2 (beta-1,6-N-acetylglucosaminyltransferase)
Synonyms: C2GNT3, LOC218476, LOC238786, Gm73
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218476
VEGA: 13
Homologene: 41144
Or52n3
Name: olfactory receptor family 52 subfamily N member 3
Synonyms: GA_x6K02T2PBJ9-7509539-7510489, MOR34-7, Olfr665
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258810
Homologene: 110477
Prss3l
Name: serine protease 3 like
Synonyms: Gm10334
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 100040233
Homologene: 88408
Abi3bp
Name: ABI family member 3 binding protein
Synonyms: TARSH, eratin, D930038M13Rik, 5033411B22Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 320712
VEGA: 16
Homologene: 134172
Dlgap1
Name: DLG associated protein 1
Synonyms: 4933422O14Rik, GKAP/SAPAP, D17Bwg0511e, SAPAP1, DAP-1 beta, Gkap, Sapap1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224997
HGNC: HGNC:2905
Homologene: 31258
Fam186b
Name: family with sequence similarity 186, member B
Synonyms: EG545136
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 545136
VEGA: 15
Homologene: 69502
Glb1l3
Name: galactosidase, beta 1 like 3
Synonyms: 4921509F24Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 70893
Homologene: 72240
Fbxw20
Name: F-box and WD-40 domain protein 20
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 434440
Homologene: 110776
Champ1
Name: chromosome alignment maintaining phosphoprotein 1
Synonyms: D8Ertd569e, Zfp828, D8Ertd457e
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 101994
Homologene: 18780
Speer4d
Name: spermatogenesis associated glutamate (E)-rich protein 4D
Synonyms: SPEER-4D
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 360220
Homologene: 69402
Plekhg2
Name: pleckstrin homology domain containing, family G (with RhoGef domain) member 2
Synonyms: Clg
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 101497
Homologene: 16341
Or5k1b
Name: olfactory receptor family 5 subfamily K member 1B
Synonyms: GA_x54KRFPKG5P-54930346-54929417, Olfr172, MOR184-2
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 259003
Homologene: 45084
Ccdc153
Name: coiled-coil domain containing 153
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 270150
VEGA: 9
Homologene: 26818
Ifnl3
Name: interferon lambda 3
Synonyms: INF-lambda, Il28, IFL-1, Il28b
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 338374
Homologene: 77540
4930523C07Rik
Name: RIKEN cDNA 4930523C07 gene
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 67647
Homologene: 124386
Ctsr
Name: cathepsin R
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 56835
VEGA: 13
Homologene: 75127
Gm8267
Name: predicted gene 8267
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 666744
Homologene: 115686
Gfy
Name: golgi-associated olfactory signaling regulator
Synonyms: Gm581, Goofy
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 100039953
Homologene: 85248
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to G, chromosome 1 at 43,075,448 bp (GRCm38)
  • G to A, chromosome 1 at 60,438,941 bp (GRCm38)
  • A to G, chromosome 1 at 66,415,338 bp (GRCm38)
  • A to T, chromosome 1 at 85,697,030 bp (GRCm38)
  • C to T, chromosome 1 at 126,024,757 bp (GRCm38)
  • A to C, chromosome 1 at 150,723,497 bp (GRCm38)
  • T to C, chromosome 1 at 160,075,295 bp (GRCm38)
  • G to T, chromosome 2 at 22,227,572 bp (GRCm38)
  • T to C, chromosome 2 at 66,223,522 bp (GRCm38)
  • T to C, chromosome 2 at 70,713,997 bp (GRCm38)
  • A to T, chromosome 2 at 122,685,280 bp (GRCm38)
  • A to G, chromosome 3 at 95,033,424 bp (GRCm38)
  • A to G, chromosome 3 at 122,120,065 bp (GRCm38)
  • T to A, chromosome 3 at 127,584,092 bp (GRCm38)
  • T to C, chromosome 4 at 116,801,246 bp (GRCm38)
  • T to C, chromosome 5 at 14,766,816 bp (GRCm38)
  • T to G, chromosome 5 at 15,623,395 bp (GRCm38)
  • G to A, chromosome 5 at 62,882,283 bp (GRCm38)
  • A to G, chromosome 5 at 122,802,146 bp (GRCm38)
  • C to A, chromosome 5 at 144,826,707 bp (GRCm38)
  • A to G, chromosome 6 at 41,443,552 bp (GRCm38)
  • T to A, chromosome 6 at 47,964,107 bp (GRCm38)
  • C to A, chromosome 6 at 122,051,731 bp (GRCm38)
  • G to C, chromosome 7 at 19,136,866 bp (GRCm38)
  • T to C, chromosome 7 at 28,362,872 bp (GRCm38)
  • T to C, chromosome 7 at 28,523,862 bp (GRCm38)
  • A to G, chromosome 7 at 44,734,342 bp (GRCm38)
  • T to C, chromosome 7 at 45,177,827 bp (GRCm38)
  • T to C, chromosome 7 at 45,524,725 bp (GRCm38)
  • T to A, chromosome 7 at 104,880,843 bp (GRCm38)
  • T to A, chromosome 7 at 120,786,459 bp (GRCm38)
  • T to A, chromosome 7 at 127,538,101 bp (GRCm38)
  • T to C, chromosome 7 at 127,591,782 bp (GRCm38)
  • G to A, chromosome 8 at 13,879,114 bp (GRCm38)
  • T to A, chromosome 8 at 36,222,870 bp (GRCm38)
  • A to G, chromosome 8 at 86,860,537 bp (GRCm38)
  • C to T, chromosome 8 at 95,103,994 bp (GRCm38)
  • A to G, chromosome 9 at 26,850,055 bp (GRCm38)
  • A to T, chromosome 9 at 44,245,714 bp (GRCm38)
  • T to C, chromosome 9 at 67,951,392 bp (GRCm38)
  • A to C, chromosome 9 at 109,221,331 bp (GRCm38)
  • G to A, chromosome 9 at 121,642,927 bp (GRCm38)
  • A to T, chromosome 9 at 122,378,964 bp (GRCm38)
  • A to T, chromosome 10 at 115,080,087 bp (GRCm38)
  • A to G, chromosome 11 at 119,317,205 bp (GRCm38)
  • A to T, chromosome 11 at 119,463,580 bp (GRCm38)
  • T to A, chromosome 12 at 4,206,939 bp (GRCm38)
  • T to A, chromosome 13 at 11,737,794 bp (GRCm38)
  • T to A, chromosome 13 at 61,159,481 bp (GRCm38)
  • T to C, chromosome 13 at 63,402,955 bp (GRCm38)
  • A to C, chromosome 13 at 68,734,657 bp (GRCm38)
  • C to T, chromosome 13 at 96,946,985 bp (GRCm38)
  • T to A, chromosome 14 at 14,937,766 bp (GRCm38)
  • T to C, chromosome 14 at 44,722,889 bp (GRCm38)
  • T to C, chromosome 14 at 101,667,015 bp (GRCm38)
  • T to C, chromosome 15 at 44,479,613 bp (GRCm38)
  • G to A, chromosome 15 at 99,279,735 bp (GRCm38)
  • A to T, chromosome 16 at 26,526,663 bp (GRCm38)
  • C to A, chromosome 16 at 56,588,683 bp (GRCm38)
  • G to T, chromosome 16 at 58,760,839 bp (GRCm38)
  • A to T, chromosome 16 at 59,555,757 bp (GRCm38)
  • G to T, chromosome 17 at 23,477,604 bp (GRCm38)
  • A to T, chromosome 17 at 70,516,969 bp (GRCm38)
  • A to C, chromosome 18 at 35,697,113 bp (GRCm38)
  • A to G, chromosome 19 at 7,614,558 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9464 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069267-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.