Strain Name:
C57BL/6J-MtgxR9480Btlr/Mmmh
Stock Number:
069283-MU
Citation ID:
RRID:MMRRC_069283-MU
Other Names:
R9480 (G1)
Major Collection:

Strain Information

Calb1
Name: calbindin 1
Synonyms: Brain-2, CB, Calb, Calb-1, CalbindinD28K, calbindin, calbindin-D (28k)
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 12307
HGNC: HGNC:1434
Homologene: 21026
Bcar3
Name: breast cancer anti-estrogen resistance 3
Synonyms: AND-34
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 29815
HGNC: HGNC:973
Homologene: 31181
Cemip2
Name: cell migration inducing hyaluronidase 2
Synonyms: Tmem2, 3110012M15Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 83921
VEGA: 19
Homologene: 75008
Zfp423
Name: zinc finger protein 423
Synonyms: Zfp104, Ebfaz, Roaz, ataxia1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 94187
Homologene: 9010
Zbtb8a
Name: zinc finger and BTB domain containing 8a
Synonyms: 2410081M15Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 73680
Homologene: 12506
Gatad2a
Name: GATA zinc finger domain containing 2A
Synonyms: 1110066C11Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234366
Homologene: 9766
Gpr55
Name: G protein-coupled receptor 55
Synonyms: CTFL, LOC227326
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 227326
HGNC: HGNC:4511
Homologene: 36184
Dlgap4
Name: DLG associated protein 4
Synonyms: WBP16, PSD-95/SAP90 binding protein 4, SAP90/PSD-95-associated protein 4, Sapap4, DAP4
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228836
Homologene: 8935
Usp48
Name: ubiquitin specific peptidase 48
Synonyms: 2810449C13Rik, Usp31, D330022K21Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 170707
Homologene: 12988
Orc4
Name: origin recognition complex, subunit 4
Synonyms: Orc4, Orc4l, Orc4P, mMmORC4
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 26428
HGNC: HGNC:8490
Homologene: 8059
Phkb
Name: phosphorylase kinase beta
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 102093
HGNC: HGNC:8927
Homologene: 247
Kat14
Name: lysine acetyltransferase 14
Synonyms: D2Ertd473e, D2Wsu131e, ATAC2, Csrp2bp, 2510008M08Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228714
Homologene: 10745
Cnot1
Name: CCR4-NOT transcription complex, subunit 1
Synonyms: 6030411K04Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234594
HGNC: HGNC:7877
Homologene: 9453
Zfp180
Name: zinc finger protein 180
Synonyms: 2310040I01Rik, HHZ168, D130011P11
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 210135
Homologene: 8306
Hipk2
Name: homeodomain interacting protein kinase 2
Synonyms: B230339E18Rik, Stank, 1110014O20Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 15258
Homologene: 68766
Ntng2
Name: netrin G2
Synonyms: Lmnt2, 2610016D08Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 171171
Homologene: 13053
Adam12
Name: ADAM metallopeptidase domain 12
Synonyms: Mltna, ADAM12
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 11489
HGNC: HGNC:190
Homologene: 74862
P4hb
Name: prolyl 4-hydroxylase, beta polypeptide
Synonyms: Pdia1, Thbp, PDI, protein disulfide isomerase, ERp59
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18453
HGNC: HGNC:8548
Homologene: 55495
Ddx21
Name: DExD box helicase 21
Synonyms: D10Ertd645e, RH II/Gu, RH-II/Gualpha, DEAD (Asp-Glu-Ala-Asp) box polypeptide 21, D10Wsu42e
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 56200
VEGA: 10
HGNC: HGNC:2744
Homologene: 3473
Tmco1
Name: transmembrane and coiled-coil domains 1
Synonyms: ESTM39, 4930403O06Rik, 1190006A08Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 68944
Homologene: 10384
Usp33
Name: ubiquitin specific peptidase 33
Synonyms: 9830169D19Rik, Vdu1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 170822
Homologene: 8996
Gin1
Name: gypsy retrotransposon integrase 1
Synonyms: 4930429M06, 4930429M06Rik, Zh2c2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 252876
Homologene: 69238
Zfp345
Name: zinc finger protein 345
Synonyms: OTTMUSG00000015743
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 545471
Homologene: 134546
Siglecf
Name: sialic acid binding Ig-like lectin F
Synonyms: Siglec5, mSiglec-F
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233186
Homologene: 50482
Fgf3
Name: fibroblast growth factor 3
Synonyms: Int-2, Fgf-3, Int-P
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 14174
HGNC: HGNC:3681
Homologene: 3841
Zfp420
Name: zinc finger protein 420
Synonyms: B230312I18Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233058
Homologene: 129731
Hgsnat
Name: heparan-alpha-glucosaminide N-acetyltransferase
Synonyms: D8Ertd354e, 9430010M12Rik, Tmem76
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 52120
Homologene: 15586
Fat3
Name: FAT atypical cadherin 3
Synonyms: D430038H04Rik, LOC382129, 9430076A06Rik, LOC234973
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 270120
VEGA: 9
Homologene: 82252
Zim1
Name: zinc finger, imprinted 1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 22776
Homologene: 129793
Krt35
Name: keratin 35
Synonyms: Krt1-24, Ha5
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 53617
HGNC: HGNC:6453
Homologene: 1715
Nlrp12
Name: NLR family, pyrin domain containing 12
Synonyms: Nalp12
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 378425
Homologene: 16972
Ttc39d
Name: tetratricopeptide repeat domain 39D
Synonyms: 4930560E09Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 67737
Homologene: 65053
Mfsd6
Name: major facilitator superfamily domain containing 6
Synonyms: MMR2, 2210010L05Rik, 9630025I22Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 98682
Homologene: 9784
Abcc6
Name: ATP-binding cassette, sub-family C member 6
Synonyms: Mrp6, DCC, Dyscalc1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 27421
HGNC: HGNC:57
Homologene: 55559
Hivep1
Name: human immunodeficiency virus type I enhancer binding protein 1
Synonyms: alphaA-CRYBP1, Cryabp1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 110521
VEGA: 13
HGNC: HGNC:4920
Homologene: 1596
Sspo
Name: SCO-spondin
Synonyms: Scospondin, C79529
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243369
Homologene: 45453
Serping1
Name: serine (or cysteine) peptidase inhibitor, clade G, member 1
Synonyms: C1 inhibitor, C1nh, C1INH
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12258
HGNC: HGNC:1228
Homologene: 44
Atrnl1
Name: attractin like 1
Synonyms: Alp
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226255
VEGA: 19
Homologene: 45809
Abraxas2
Name: BRISC complex subunit
Synonyms: KIAA0157, Fam175b, C430003P19Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 109359
Homologene: 12970
Sytl2
Name: synaptotagmin-like 2
Synonyms: Slp2-b, Slp2-c, Slp2-d, Slp2, Slp2-a
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 83671
Homologene: 131343
Adam22
Name: a disintegrin and metallopeptidase domain 22
Synonyms: 2900022I03Rik, MDC2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 11496
HGNC: HGNC:201
Homologene: 37898
Zfp820
Name: zinc finger protein 820
Synonyms: 2610036F08Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 75424
VEGA: 17
Sh2d2a
Name: SH2 domain containing 2A
Synonyms: RIBP, Lck-associated adapter protein, Lad, TSAd, Rlk/Itk-binding protein
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 27371
Homologene: 2958
Klhl25
Name: kelch-like 25
Synonyms: 2810402K13Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 207952
Homologene: 32546
Apcdd1
Name: adenomatosis polyposis coli down-regulated 1
Synonyms: Drapc1, EIG180
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 494504
VEGA: 18
Homologene: 77420
Lipk
Name: lipase, family member K
Synonyms: Lipl2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 240633
VEGA: 19
Homologene: 75666
Poldip2
Name: polymerase (DNA-directed), delta interacting protein 2
Synonyms: 1300003F06Rik, mitogenin 1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 67811
Homologene: 9201
Lhfpl2
Name: lipoma HMGIC fusion partner-like 2
Synonyms: vgim
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218454
HGNC: HGNC:6588
Homologene: 4222
Lrrc39
Name: leucine rich repeat containing 39
Synonyms: 9430028I06Rik, Myomasp, 2010005E21Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 109245
Homologene: 13668
Abcc1
Name: ATP-binding cassette, sub-family C member 1
Synonyms: Mdrap, MRP, Mrp1, Abcc1a, Abcc1b
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 17250
HGNC: HGNC:51
Homologene: 133779
Prkd1
Name: protein kinase D1
Synonyms: Pkcm, PKD1, Prkcm
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 18760
VEGA: 12
HGNC: HGNC:9407
Homologene: 55680
Anapc11
Name: anaphase promoting complex subunit 11
Synonyms: 1110011I19Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 66156
Homologene: 41136
Dus2
Name: dihydrouridine synthase 2
Synonyms: 2310016K04Rik, Dus2l
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 66369
Homologene: 6838
Zbtb49
Name: zinc finger and BTB domain containing 49
Synonyms: Zfp509, 4930518A03Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 75079
Homologene: 34825
Zpld2
Name: zona pellucida like domain containing 2
Synonyms: Gm7534
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 665186
Homologene: 104039
Galnt17
Name: polypeptide N-acetylgalactosaminyltransferase 17
Synonyms: Galnt19, Wbscr17, Gcap8, E330012B09Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 212996
Homologene: 49707
Col23a1
Name: collagen, type XXIII, alpha 1
Synonyms: 2810458L13Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237759
Homologene: 72101
Tmc7
Name: transmembrane channel-like gene family 7
Synonyms: C630024K23Rik, 1700030H01Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 209760
Homologene: 36424
Mtfmt
Name: mitochondrial methionyl-tRNA formyltransferase
Synonyms: 2310020P08Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 69606
Homologene: 12320
Cxcl2
Name: C-X-C motif chemokine ligand 2
Synonyms: Scyb, MIP-2, Mip2, GROb, Scyb2, Mgsa-b, Gro2, MIP-2a, CINC-2a
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 20310
Homologene: 117695
Mesp2
Name: mesoderm posterior 2
Synonyms: bHLHc6
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 17293
Homologene: 7420
Ceacam9
Name: CEA cell adhesion molecule 9
Synonyms: Cea-5, Cea5, mmCGM8
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 26368
Homologene: 74987
Ltb4r2
Name: leukotriene B4 receptor 2
Synonyms: 5830462O07Rik, BLT2
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 57260
VEGA: 14
Homologene: 10519
Chst13
Name: carbohydrate sulfotransferase 13
Synonyms: Chst13, 1110067M19Rik, C4ST-3
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 71797
Homologene: 44360
Nxt2
Name: nuclear transport factor 2-like export factor 2
Synonyms: 6330587F24Rik, P15-2
Type: Gene
Species: Mouse
Chromosome: X
NCBI: 237082
Homologene: 10273
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to G, chromosome 1 at 52,660,676 bp (GRCm38)
  • A to C, chromosome 1 at 85,941,255 bp (GRCm38)
  • A to G, chromosome 1 at 97,777,473 bp (GRCm38)
  • C to T, chromosome 1 at 167,330,188 bp (GRCm38)
  • T to A, chromosome 2 at 29,247,985 bp (GRCm38)
  • T to C, chromosome 2 at 48,905,551 bp (GRCm38)
  • C to T, chromosome 2 at 84,770,143 bp (GRCm38)
  • T to A, chromosome 2 at 144,373,825 bp (GRCm38)
  • A to T, chromosome 2 at 150,473,292 bp (GRCm38)
  • G to T, chromosome 2 at 156,704,594 bp (GRCm38)
  • A to C, chromosome 3 at 87,852,331 bp (GRCm38)
  • T to A, chromosome 3 at 116,565,826 bp (GRCm38)
  • C to T, chromosome 3 at 122,483,969 bp (GRCm38)
  • T to G, chromosome 3 at 152,373,449 bp (GRCm38)
  • T to A, chromosome 4 at 15,885,608 bp (GRCm38)
  • G to T, chromosome 4 at 129,360,082 bp (GRCm38)
  • G to A, chromosome 4 at 134,202,001 bp (GRCm38)
  • G to A, chromosome 4 at 137,613,685 bp (GRCm38)
  • A to G, chromosome 5 at 8,143,077 bp (GRCm38)
  • T to A, chromosome 5 at 38,201,065 bp (GRCm38)
  • T to C, chromosome 5 at 90,904,170 bp (GRCm38)
  • T to A, chromosome 5 at 130,906,738 bp (GRCm38)
  • G to T, chromosome 6 at 38,703,442 bp (GRCm38)
  • A to G, chromosome 6 at 48,493,886 bp (GRCm38)
  • G to A, chromosome 6 at 90,309,524 bp (GRCm38)
  • A to T, chromosome 7 at 3,240,363 bp (GRCm38)
  • T to C, chromosome 7 at 6,678,051 bp (GRCm38)
  • A to G, chromosome 7 at 16,723,858 bp (GRCm38)
  • A to G, chromosome 7 at 24,105,203 bp (GRCm38)
  • T to A, chromosome 7 at 29,876,072 bp (GRCm38)
  • G to T, chromosome 7 at 43,352,242 bp (GRCm38)
  • A to G, chromosome 7 at 45,979,773 bp (GRCm38)
  • T to C, chromosome 7 at 75,866,372 bp (GRCm38)
  • A to G, chromosome 7 at 79,811,286 bp (GRCm38)
  • C to T, chromosome 7 at 90,371,510 bp (GRCm38)
  • A to G, chromosome 7 at 118,542,003 bp (GRCm38)
  • G to T, chromosome 7 at 132,871,594 bp (GRCm38)
  • T to A, chromosome 7 at 134,134,741 bp (GRCm38)
  • G to T, chromosome 7 at 144,842,882 bp (GRCm38)
  • T to C, chromosome 8 at 25,952,001 bp (GRCm38)
  • T to C, chromosome 8 at 69,935,809 bp (GRCm38)
  • T to G, chromosome 8 at 85,957,587 bp (GRCm38)
  • A to G, chromosome 8 at 87,904,487 bp (GRCm38)
  • T to C, chromosome 8 at 95,770,710 bp (GRCm38)
  • C to T, chromosome 8 at 106,030,420 bp (GRCm38)
  • T to C, chromosome 9 at 16,031,407 bp (GRCm38)
  • A to T, chromosome 9 at 65,443,899 bp (GRCm38)
  • T to C, chromosome 10 at 62,598,873 bp (GRCm38)
  • T to A, chromosome 11 at 51,316,947 bp (GRCm38)
  • T to C, chromosome 11 at 78,521,162 bp (GRCm38)
  • T to C, chromosome 11 at 100,095,783 bp (GRCm38)
  • A to T, chromosome 11 at 120,572,725 bp (GRCm38)
  • T to A, chromosome 11 at 120,605,350 bp (GRCm38)
  • T to A, chromosome 12 at 50,388,500 bp (GRCm38)
  • A to T, chromosome 13 at 42,183,582 bp (GRCm38)
  • T to A, chromosome 13 at 94,174,225 bp (GRCm38)
  • T to A, chromosome 14 at 55,762,632 bp (GRCm38)
  • T to A, chromosome 16 at 14,394,025 bp (GRCm38)
  • T to A, chromosome 17 at 21,819,013 bp (GRCm38)
  • A to G, chromosome 17 at 80,216,710 bp (GRCm38)
  • C to T, chromosome 18 at 62,922,660 bp (GRCm38)
  • C to A, chromosome 19 at 21,798,258 bp (GRCm38)
  • T to A, chromosome 19 at 34,021,701 bp (GRCm38)
  • T to A, chromosome 19 at 57,701,988 bp (GRCm38)
  • C to T, chromosome X at 142,237,751 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9480 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069283-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.