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Strain Name:
C57BL/6J-MtgxR9486Btlr/Mmmh
Stock Number:
069289-MU
Citation ID:
RRID:MMRRC_069289-MU
Other Names:
R9486 (G1)
Major Collection:

Strain Information

Epyc
Name: epiphycan
Synonyms: PG-Lb, epiphycan, SLRR3B, Dspg3
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 13516
HGNC: HGNC:3053
Homologene: 3634
Pcdh9
Name: protocadherin 9
Synonyms: C630029H24Rik, 1500001L12Rik, LOC382930, A730003J17Rik, C530050I23Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 211712
HGNC: HGNC:8661
Homologene: 10698
Slc17a7
Name: solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
Synonyms: Vglut1, 2900052E22Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 72961
Homologene: 113454
Pkp4
Name: plakophilin 4
Synonyms: p0071, Armrp, 5031422I09Rik, 9430019K17Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227937
HGNC: HGNC:9026
Homologene: 2689
Kdm4c
Name: lysine (K)-specific demethylase 4C
Synonyms: 2410141F18Rik, Jmjd2c
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 76804
Homologene: 41004
Sipa1l1
Name: signal-induced proliferation-associated 1 like 1
Synonyms: 4931426N11Rik, Spar
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217692
VEGA: 12
Homologene: 9189
Hspa12a
Name: heat shock protein 12A
Synonyms: Hspa12a, 1700063D12Rik, Gm19925
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 73442
VEGA: 19
Homologene: 18422
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to C, chromosome 1 at 53,813,307 bp (GRCm38)
  • A to T, chromosome 1 at 80,501,735 bp (GRCm38)
  • T to A, chromosome 1 at 106,543,379 bp (GRCm38)
  • T to C, chromosome 1 at 162,880,723 bp (GRCm38)
  • A to G, chromosome 1 at 181,680,929 bp (GRCm38)
  • T to A, chromosome 2 at 25,565,152 bp (GRCm38)
  • T to C, chromosome 2 at 59,308,378 bp (GRCm38)
  • A to G, chromosome 2 at 71,532,484 bp (GRCm38)
  • C to T, chromosome 2 at 89,406,615 bp (GRCm38)
  • A to T, chromosome 2 at 152,885,013 bp (GRCm38)
  • A to G, chromosome 2 at 174,426,842 bp (GRCm38)
  • C to T, chromosome 3 at 40,835,192 bp (GRCm38)
  • A to T, chromosome 3 at 89,212,856 bp (GRCm38)
  • G to A, chromosome 3 at 90,406,272 bp (GRCm38)
  • T to A, chromosome 4 at 74,334,729 bp (GRCm38)
  • T to A, chromosome 4 at 81,335,806 bp (GRCm38)
  • A to G, chromosome 4 at 98,736,662 bp (GRCm38)
  • T to C, chromosome 4 at 115,249,719 bp (GRCm38)
  • T to A, chromosome 5 at 33,861,149 bp (GRCm38)
  • T to A, chromosome 5 at 108,403,375 bp (GRCm38)
  • C to A, chromosome 5 at 109,676,196 bp (GRCm38)
  • A to G, chromosome 5 at 121,439,895 bp (GRCm38)
  • A to T, chromosome 6 at 57,900,419 bp (GRCm38)
  • A to T, chromosome 6 at 71,707,985 bp (GRCm38)
  • A to G, chromosome 6 at 128,569,979 bp (GRCm38)
  • G to A, chromosome 6 at 143,184,584 bp (GRCm38)
  • T to C, chromosome 7 at 29,078,540 bp (GRCm38)
  • G to T, chromosome 7 at 44,529,391 bp (GRCm38)
  • A to G, chromosome 7 at 45,172,182 bp (GRCm38)
  • C to T, chromosome 7 at 103,250,174 bp (GRCm38)
  • C to T, chromosome 7 at 142,356,075 bp (GRCm38)
  • A to G, chromosome 9 at 7,451,256 bp (GRCm38)
  • C to A, chromosome 9 at 88,570,129 bp (GRCm38)
  • A to G, chromosome 9 at 106,858,717 bp (GRCm38)
  • C to T, chromosome 9 at 107,659,123 bp (GRCm38)
  • G to A, chromosome 9 at 108,575,983 bp (GRCm38)
  • T to C, chromosome 9 at 108,982,328 bp (GRCm38)
  • T to G, chromosome 9 at 119,795,708 bp (GRCm38)
  • A to G, chromosome 10 at 44,004,149 bp (GRCm38)
  • T to A, chromosome 10 at 69,270,791 bp (GRCm38)
  • T to A, chromosome 10 at 77,988,350 bp (GRCm38)
  • C to T, chromosome 10 at 80,530,987 bp (GRCm38)
  • A to G, chromosome 10 at 97,675,835 bp (GRCm38)
  • A to G, chromosome 10 at 114,696,109 bp (GRCm38)
  • T to A, chromosome 10 at 116,319,589 bp (GRCm38)
  • T to C, chromosome 11 at 9,290,621 bp (GRCm38)
  • T to A, chromosome 11 at 50,984,864 bp (GRCm38)
  • T to C, chromosome 11 at 59,027,446 bp (GRCm38)
  • A to T, chromosome 11 at 101,523,694 bp (GRCm38)
  • A to T, chromosome 11 at 106,005,393 bp (GRCm38)
  • T to C, chromosome 12 at 82,357,365 bp (GRCm38)
  • G to T, chromosome 12 at 83,535,952 bp (GRCm38)
  • A to G, chromosome 12 at 83,992,652 bp (GRCm38)
  • T to A, chromosome 12 at 84,831,874 bp (GRCm38)
  • C to T, chromosome 12 at 86,983,624 bp (GRCm38)
  • T to A, chromosome 12 at 87,959,193 bp (GRCm38)
  • A to G, chromosome 13 at 58,344,534 bp (GRCm38)
  • T to A, chromosome 14 at 33,351,346 bp (GRCm38)
  • T to A, chromosome 14 at 50,148,215 bp (GRCm38)
  • T to C, chromosome 14 at 70,589,039 bp (GRCm38)
  • A to G, chromosome 14 at 93,560,520 bp (GRCm38)
  • T to G, chromosome 15 at 36,181,808 bp (GRCm38)
  • A to T, chromosome 16 at 32,794,878 bp (GRCm38)
  • A to T, chromosome 16 at 33,185,913 bp (GRCm38)
  • A to T, chromosome 16 at 37,593,449 bp (GRCm38)
  • C to T, chromosome 17 at 12,270,973 bp (GRCm38)
  • T to C, chromosome 17 at 32,398,936 bp (GRCm38)
  • T to A, chromosome 19 at 39,767,364 bp (GRCm38)
  • A to T, chromosome 19 at 39,807,606 bp (GRCm38)
  • A to G, chromosome 19 at 54,047,532 bp (GRCm38)
  • A to G, chromosome 19 at 58,809,459 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain GQC Summary
The MMRRC Centers have developed a Strain GQC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC strains. For more information on whether data may be available, or to request genotyping for a strain of interest, please contact MMRRC_GeneticQC@med.unc.edu. Older strains may not have this information available.
Suggested Control Mice
Littermates of all relevant genotypes.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9486 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.


Disclaimer: If MMRRC Strain Genetic Quality Control (GQC; based on MiniMUGA genotyping and analysis) has been completed for this strain, the information might differ from the genetic background information provided by the submitter. MiniMUGA genetic analysis is done on a strain’s tissue samples taken when archived by or ordered from the assigned MMRRC Center.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069289-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.