Strain Name:
C57BL/6J-MtgxR9512Btlr/Mmmh
Stock Number:
069314-MU
Citation ID:
RRID:MMRRC_069314-MU
Other Names:
R9512 (G1)
Major Collection:

Strain Information

Ppp1r9a
Name: protein phosphatase 1, regulatory subunit 9A
Synonyms: NRB, neurabin-I, 2810430P21Rik, A230094E16Rik, Neurabin I, 4930518N04Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243725
Homologene: 14247
Alkbh8
Name: alkB homolog 8, tRNA methyltransferase
Synonyms: 4930562C03Rik, Abh8, 9430088N01Rik, 8030431D03Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 67667
Homologene: 44488
Nln
Name: neurolysin (metallopeptidase M3 family)
Synonyms: 4930472G13Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 75805
VEGA: 13
Homologene: 69315
Orc6
Name: origin recognition complex, subunit 6
Synonyms: Orc6l, 6720420I10Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 56452
Homologene: 8635
Eif2ak4
Name: eukaryotic translation initiation factor 2 alpha kinase 4
Synonyms: GCN2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 27103
Homologene: 40891
Fndc3a
Name: fibronectin type III domain containing 3A
Synonyms: 1700094E19Rik, F730017H24Rik, Fndc3, D14Ertd453e, sys
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 319448
Homologene: 8952
Kif18a
Name: kinesin family member 18A
Synonyms: B130001M12Rik, N-8 kinesin, gcd2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228421
Homologene: 41820
Ap1g1
Name: adaptor protein complex AP-1, gamma 1 subunit
Synonyms: D8Ertd374e, gamma-adaptin, Adtg
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 11765
HGNC: HGNC:555
Homologene: 47995
Arid1b
Name: AT-rich interaction domain 1B
Synonyms: 9330189K18Rik, B230217J03Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 239985
Homologene: 32344
Snap91
Name: synaptosomal-associated protein 91
Synonyms: AP180, 91kDa, F1-20
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 20616
Homologene: 8429
Slitrk5
Name: SLIT and NTRK-like family, member 5
Synonyms: 2610019D03Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 75409
VEGA: 14
Homologene: 9193
Ntng2
Name: netrin G2
Synonyms: Lmnt2, 2610016D08Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 171171
Homologene: 13053
Plk2
Name: polo like kinase 2
Synonyms: Snk
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 20620
VEGA: 13
Homologene: 21317
Brca2
Name: breast cancer 2, early onset
Synonyms: RAB163, Fancd1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 12190
HGNC: HGNC:1101
Homologene: 41
Esrp1
Name: epithelial splicing regulatory protein 1
Synonyms: Rbm35a, 2210008M09Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 207920
Homologene: 9785
Abca16
Name: ATP-binding cassette, sub-family A member 16
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233810
Homologene: 132942
Slc9a2
Name: solute carrier family 9 (sodium/hydrogen exchanger), member 2
Synonyms: NHE2, 4932415O19Rik, 2210416H12Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226999
Homologene: 20661
Psd
Name: pleckstrin and Sec7 domain containing
Synonyms: Psdl, Efa6, Efa6a, 1110007H17Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 73728
VEGA: 19
HGNC: HGNC:9507
Homologene: 31115
Ush2a
Name: usherin
Synonyms: MUSH2A, LOC269160, Ush2a, A930037M10Rik, A930011D15Rik, LOC381317, Ushrn
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 22283
Homologene: 66151
Mroh4
Name: maestro heat-like repeat family member 4
Synonyms: 1700016M24Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 69439
Homologene: 72545
Ephb6
Name: Eph receptor B6
Synonyms: Mep, Cekl
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 13848
HGNC: HGNC:3396
Homologene: 20940
Abcb9
Name: ATP-binding cassette, sub-family B member 9
Synonyms: TAPL
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 56325
HGNC: HGNC:50
Homologene: 10491
Ltbp2
Name: latent transforming growth factor beta binding protein 2
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 16997
HGNC: HGNC:6715
Homologene: 369
Henmt1
Name: HEN1 methyltransferase homolog 1 (Arabidopsis)
Synonyms: Hen1, 4921515J06Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 66715
Homologene: 32638
Capn3
Name: calpain 3
Synonyms: p94, Capa-3, Lp82, Capa3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12335
HGNC: HGNC:1480
Homologene: 52
Fyb2
Name: FYN binding protein 2
Synonyms: 1700024P16Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242594
Homologene: 52981
Spata16
Name: spermatogenesis associated 16
Synonyms: Nyd-sp12, spermatogenesis-related protein, 4930503K02Rik, 4921511F01Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 70862
Homologene: 49974
Meiosin
Name: meiosis initiator
Synonyms: Bhmg1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243866
Homologene: 131804
Nrg2
Name: neuregulin 2
Synonyms: Don1, NTAK
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 100042150
HGNC: HGNC:7998
Homologene: 75024
Or9s14
Name: olfactory receptor family 9 subfamily S member 14
Synonyms: Olfr1410, GA_x6K02T2R7CC-81146179-81145211, MOR208-2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 258484
Homologene: 74205
Zfp616
Name: zinc finger protein 616
Synonyms: Gm12330
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 327963
Homologene: 88945
Foxn1
Name: forkhead box N1
Synonyms: Hfh11, whn, D11Bhm185e
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 15218
Homologene: 2664
Hsdl2
Name: hydroxysteroid dehydrogenase like 2
Synonyms: 2610207I16Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 72479
Lrrcc1
Name: leucine rich repeat and coiled-coil domain containing 1
Synonyms: 4932441F23Rik, 1200008A14Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 71710
Homologene: 12559
Or2n1d
Name: olfactory receptor family 2 subfamily N member 1D
Synonyms: Olfr136, GA_x6K02T2PSCP-2779375-2780313, MOR256-7
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 258803
Homologene: 119758
Stard6
Name: StAR related lipid transfer domain containing 6
Synonyms: 4833424I06Rik, 1700011K09Rik, 4933429L05Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 170461
Homologene: 12578
Or1j10
Name: olfactory receptor family 1 subfamily J member 10
Synonyms: MOR136-5, GA_x6K02T2NLDC-33070879-33071799, Olfr338
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258949
Homologene: 133647
Bnipl
Name: BCL2/adenovirus E1B 19kD interacting protein like
Synonyms: BNIPL2, PP753, BNIPL-1, BNIPL, BNIP-S, BNIPL-2, 1700128A13Rik, BNIPL1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 171388
Homologene: 15900
Toporsl
Name: topoisomerase I binding, arginine/serine-rich like
Synonyms: 4930547C10Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 68274
Homologene: 130753
Vmn1r232
Name: vomeronasal 1 receptor 232
Synonyms: V1re4
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 171227
Homologene: 121611
Zfp263
Name: zinc finger protein 263
Synonyms: 1200014J04Rik, mFPM315, NT2
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 74120
Homologene: 4197
Stra8
Name: stimulated by retinoic acid gene 8
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 20899
Homologene: 49197
Pou1f1
Name: POU domain, class 1, transcription factor 1
Synonyms: Pit-1, Pit1-rs1, Hmp1, GHF-1, Pit1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 18736
HGNC: HGNC:9210
Homologene: 259
Pcdha8
Name: protocadherin alpha 8
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 353235
HGNC: HGNC:8675
Homologene: 129614
Slc25a51
Name: solute carrier family 25, member 51
Synonyms: Mcart1, D130005A03Rik, 9130208E07Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230125
Homologene: 88487
Or4x12-ps1
Name: olfactory receptor family 4 subfamily X member 12, pseudogene 1
Synonyms: MOR228-1, GA_x6K02T2Q125-51518604-51517675, Olfr1267-ps1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258204
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to G, chromosome 1 at 40,682,098 bp (GRCm38)
  • T to C, chromosome 1 at 92,608,268 bp (GRCm38)
  • A to G, chromosome 1 at 188,910,963 bp (GRCm38)
  • T to C, chromosome 2 at 29,227,957 bp (GRCm38)
  • T to C, chromosome 2 at 36,377,313 bp (GRCm38)
  • A to G, chromosome 2 at 90,086,377 bp (GRCm38)
  • A to G, chromosome 2 at 109,341,172 bp (GRCm38)
  • G to A, chromosome 2 at 118,462,715 bp (GRCm38)
  • G to A, chromosome 2 at 120,496,054 bp (GRCm38)
  • T to C, chromosome 3 at 14,548,241 bp (GRCm38)
  • G to C, chromosome 3 at 26,667,944 bp (GRCm38)
  • A to G, chromosome 3 at 95,243,058 bp (GRCm38)
  • A to G, chromosome 3 at 108,960,129 bp (GRCm38)
  • A to G, chromosome 4 at 11,365,449 bp (GRCm38)
  • T to C, chromosome 4 at 45,399,360 bp (GRCm38)
  • A to G, chromosome 4 at 52,610,382 bp (GRCm38)
  • A to T, chromosome 4 at 59,594,464 bp (GRCm38)
  • G to A, chromosome 4 at 104,995,903 bp (GRCm38)
  • T to C, chromosome 5 at 124,090,113 bp (GRCm38)
  • C to T, chromosome 5 at 150,531,081 bp (GRCm38)
  • A to T, chromosome 6 at 5,113,681 bp (GRCm38)
  • T to C, chromosome 6 at 5,115,364 bp (GRCm38)
  • G to A, chromosome 6 at 34,933,053 bp (GRCm38)
  • G to A, chromosome 6 at 41,616,096 bp (GRCm38)
  • T to A, chromosome 7 at 19,104,935 bp (GRCm38)
  • C to T, chromosome 7 at 120,423,740 bp (GRCm38)
  • T to A, chromosome 8 at 85,302,893 bp (GRCm38)
  • T to C, chromosome 8 at 109,803,055 bp (GRCm38)
  • G to T, chromosome 9 at 3,367,959 bp (GRCm38)
  • T to G, chromosome 9 at 86,783,339 bp (GRCm38)
  • G to A, chromosome 11 at 74,085,110 bp (GRCm38)
  • G to T, chromosome 11 at 78,371,209 bp (GRCm38)
  • G to A, chromosome 12 at 84,791,090 bp (GRCm38)
  • A to T, chromosome 13 at 104,061,766 bp (GRCm38)
  • C to T, chromosome 13 at 110,400,139 bp (GRCm38)
  • T to C, chromosome 14 at 72,589,984 bp (GRCm38)
  • A to G, chromosome 14 at 111,679,820 bp (GRCm38)
  • C to A, chromosome 15 at 74,613,246 bp (GRCm38)
  • T to C, chromosome 16 at 3,746,442 bp (GRCm38)
  • A to G, chromosome 16 at 65,523,616 bp (GRCm38)
  • A to G, chromosome 17 at 5,341,589 bp (GRCm38)
  • A to C, chromosome 17 at 20,914,154 bp (GRCm38)
  • A to T, chromosome 17 at 38,335,429 bp (GRCm38)
  • A to G, chromosome 18 at 36,045,957 bp (GRCm38)
  • A to C, chromosome 18 at 36,993,571 bp (GRCm38)
  • G to A, chromosome 18 at 70,500,530 bp (GRCm38)
  • T to C, chromosome 19 at 46,317,715 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9512 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069314-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.