Strain Name:
C57BL/6J-MtgxR9535Btlr/Mmmh
Stock Number:
069334-MU
Citation ID:
RRID:MMRRC_069334-MU
Other Names:
R9535 (G1)
Major Collection:

Strain Information

Nrg1
Name: neuregulin 1
Synonyms: GGFII, HGL, Hgl, SMDF, GGF, HRG, D230005F13Rik, ARIA, HRGalpha, heregulin, 6030402G23Rik, NDF
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 211323
HGNC: HGNC:7997
Homologene: 138451
Cdkal1
Name: CDK5 regulatory subunit associated protein 1-like 1
Synonyms: 6620401C13Rik, 1190005B03Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 68916
Homologene: 9830
Pwp1
Name: PWP1 homolog, endonuclein
Synonyms: 2610205J09Rik, 2310058A11Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 103136
Homologene: 5129
Tasor2
Name: transcription activation suppressor family member 2
Synonyms: Fam208b, BC016423
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 105203
VEGA: 13
Homologene: 26435
Lig4
Name: ligase IV, DNA, ATP-dependent
Synonyms: DNA ligase IV, tiny, 5830471N16Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 319583
HGNC: HGNC:6601
Homologene: 1736
Muc15
Name: mucin 15
Synonyms: D730046L02Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 269328
Homologene: 51680
Xrcc4
Name: X-ray repair complementing defective repair in Chinese hamster cells 4
Synonyms: 2310057B22Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 108138
Homologene: 2555
Synrg
Name: synergin, gamma
Synonyms: L71-5, Ap1gbp1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217030
HGNC: HGNC:557
Homologene: 105680
Wwtr1
Name: WW domain containing transcription regulator 1
Synonyms: transcriptional coactivator with PDZ binding motif, TAZ, 2610021I22Rik, 2310058J06Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 97064
Homologene: 9159
Kdm6b
Name: KDM1 lysine (K)-specific demethylase 6B
Synonyms: Jmjd3
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216850
Homologene: 18945
Siglece
Name: sialic acid binding Ig-like lectin E
Synonyms: mSiglec-E, Siglec5, Siglecl1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 83382
Homologene: 130669
Dennd5b
Name: DENN domain containing 5B
Synonyms: 9330160C06Rik, D030011O10Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 320560
Homologene: 44911
Cpa1
Name: carboxypeptidase A1, pancreatic
Synonyms: 0910001L12Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 109697
HGNC: HGNC:2296
Homologene: 55609
Atmin
Name: ATM interactor
Synonyms: Asciz, gpg6
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234776
Homologene: 35321
Tecta
Name: tectorin alpha
Synonyms: Tctna, [a]-tectorin
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 21683
Homologene: 3955
Prdm1
Name: PR domain containing 1, with ZNF domain
Synonyms: Blimp1, Blimp-1, PRDI-BF1, b2b1765Clo
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 12142
HGNC: HGNC:9346
Homologene: 925
Usp40
Name: ubiquitin specific peptidase 40
Synonyms: B230215L03Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 227334
Homologene: 32400
Spata31e2
Name: spermatogenesis associated 31 subfamily E member 2
Synonyms: 4931408C20Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 210940
Homologene: 86827
Abcc6
Name: ATP-binding cassette, sub-family C member 6
Synonyms: Dyscalc1, Mrp6, DCC
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 27421
HGNC: HGNC:57
Homologene: 55559
Glmn
Name: glomulin, FKBP associated protein
Synonyms: 9330160J16Rik, Fap68, Fap48
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 170823
Homologene: 14239
Mpo
Name: myeloperoxidase
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17523
HGNC: HGNC:7218
Homologene: 55450
Mrps34
Name: mitochondrial ribosomal protein S34
Synonyms: 0610007F04Rik, 5330430D13Rik, Tce2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 79044
Homologene: 32562
Krt84
Name: keratin 84
Synonyms: HRb-1, Krt2-16, Krt2-3
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 16680
VEGA: 15
HGNC: HGNC:6461
Homologene: 22473
Tmed11
Name: transmembrane p24 trafficking protein 11
Synonyms: 1810008K16Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 67366
Homologene: 48721
Rtl1
Name: retrotransposon Gaglike 1
Synonyms: Mart1, Mor1, Mar
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 353326
VEGA: 12
Homologene: 120261
Il18rap
Name: interleukin 18 receptor accessory protein
Synonyms: AcPL accessory protein-like)
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16174
HGNC: HGNC:5989
Homologene: 2859
Dnm1
Name: dynamin 1
Synonyms: Ftfl, dynamin 1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 13429
HGNC: HGNC:2972
Homologene: 123905
Ptprb
Name: protein tyrosine phosphatase receptor type B
Synonyms: VE-PTP, 3230402H02Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 19263
VEGA: 10
HGNC: HGNC:9665
Homologene: 2125
Mpv17l
Name: Mpv17 transgene, kidney disease mutant-like
Synonyms: M-LP
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 93734
Homologene: 13547
D6Ertd527e
Name: DNA segment, Chr 6, ERATO Doi 527, expressed
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 52372
Ttll3
Name: tubulin tyrosine ligase-like family, member 3
Synonyms: 4833441J24Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 101100
Homologene: 134361
Slc27a3
Name: solute carrier family 27 (fatty acid transporter), member 3
Synonyms: FATP3, Acsvl3, fatty acid transport protein 3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 26568
Homologene: 11529
Vmn1r236
Name: vomeronasal 1 receptor 236
Synonyms: V1rf4
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 171235
Chrng
Name: cholinergic receptor, nicotinic, gamma polypeptide
Synonyms: Acrg, Achr-3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 11449
HGNC: HGNC:1967
Homologene: 3810
Ccdc121
Name: coiled-coil domain containing 121
Synonyms: 4930548H24Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 67656
4930583I09Rik
Name: RIKEN cDNA 4930583I09 gene
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 78057
VEGA: 17
Alad
Name: aminolevulinate, delta-, dehydratase
Synonyms: Lv
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 17025
HGNC: HGNC:395
Homologene: 16
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to C, chromosome 1 at 26,682,151 bp (GRCm38)
  • T to A, chromosome 1 at 40,547,830 bp (GRCm38)
  • C to T, chromosome 1 at 87,211,480 bp (GRCm38)
  • T to C, chromosome 1 at 88,007,439 bp (GRCm38)
  • A to T, chromosome 2 at 32,312,332 bp (GRCm38)
  • T to A, chromosome 2 at 110,731,662 bp (GRCm38)
  • T to C, chromosome 3 at 57,477,404 bp (GRCm38)
  • A to G, chromosome 3 at 90,386,311 bp (GRCm38)
  • T to C, chromosome 4 at 62,510,540 bp (GRCm38)
  • A to G, chromosome 5 at 31,487,610 bp (GRCm38)
  • A to T, chromosome 5 at 107,558,502 bp (GRCm38)
  • A to G, chromosome 5 at 108,779,049 bp (GRCm38)
  • G to T, chromosome 6 at 30,641,848 bp (GRCm38)
  • G to C, chromosome 6 at 87,111,857 bp (GRCm38)
  • C to T, chromosome 6 at 113,412,873 bp (GRCm38)
  • T to C, chromosome 6 at 148,993,867 bp (GRCm38)
  • A to G, chromosome 7 at 43,657,631 bp (GRCm38)
  • A to G, chromosome 7 at 45,977,263 bp (GRCm38)
  • C to A, chromosome 8 at 9,972,325 bp (GRCm38)
  • T to C, chromosome 8 at 31,949,967 bp (GRCm38)
  • A to G, chromosome 8 at 116,956,588 bp (GRCm38)
  • T to A, chromosome 9 at 42,359,463 bp (GRCm38)
  • T to C, chromosome 10 at 44,441,612 bp (GRCm38)
  • C to A, chromosome 10 at 85,888,094 bp (GRCm38)
  • T to C, chromosome 10 at 116,322,526 bp (GRCm38)
  • C to A, chromosome 11 at 69,406,450 bp (GRCm38)
  • T to A, chromosome 11 at 83,990,834 bp (GRCm38)
  • T to A, chromosome 11 at 87,799,968 bp (GRCm38)
  • T to C, chromosome 12 at 109,590,737 bp (GRCm38)
  • T to C, chromosome 12 at 109,595,264 bp (GRCm38)
  • T to A, chromosome 13 at 3,573,559 bp (GRCm38)
  • A to G, chromosome 13 at 29,850,024 bp (GRCm38)
  • T to A, chromosome 13 at 89,940,999 bp (GRCm38)
  • A to G, chromosome 15 at 101,529,581 bp (GRCm38)
  • A to G, chromosome 16 at 13,941,285 bp (GRCm38)
  • C to T, chromosome 17 at 21,287,156 bp (GRCm38)
  • T to C, chromosome 17 at 24,895,477 bp (GRCm38)
  • T to A, chromosome 17 at 64,834,331 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9535 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069334-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.