Strain Name:
C57BL/6J-MtgxR9595Btlr/Mmmh
Stock Number:
069388-MU
Citation ID:
RRID:MMRRC_069388-MU
Other Names:
R9595 (G1)
Major Collection:

Strain Information

Sp4
Name: trans-acting transcription factor 4
Synonyms: HF-1b, HF1-b, 5730497N03Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 20688
VEGA: 12
Homologene: 2341
Wrn
Name: Werner syndrome RecQ like helicase
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 22427
Homologene: 6659
Cd86
Name: CD86 antigen
Synonyms: MB7-2, Ly58, Cd28l2, B70, B7.2, B7-2, Ly-58
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 12524
HGNC: HGNC:1705
Homologene: 10443
Slit1
Name: slit guidance ligand 1
Synonyms: Slil1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 20562
Homologene: 2302
Tns3
Name: tensin 3
Synonyms: TEM6, F830010I22Rik, Tens1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 319939
Homologene: 49713
Dennd2b
Name: DENN domain containing 2B
Synonyms: St5, Denn2b, 2010004M01Rik, 2610305K15Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 76954
Homologene: 3951
Hdac5
Name: histone deacetylase 5
Synonyms: mHDA1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 15184
Homologene: 3995
Osbpl8
Name: oxysterol binding protein-like 8
Synonyms: D330025H14Rik, ORP-8
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 237542
VEGA: 10
Homologene: 68813
Phyhipl
Name: phytanoyl-CoA hydroxylase interacting protein-like
Synonyms: PHY2, 4921522K17Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 70911
Homologene: 13028
Son
Name: Son DNA binding protein
Synonyms: 2900011L12Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 20658
Homologene: 10551
Sh3glb2
Name: SH3-domain GRB2-like endophilin B2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227700
Homologene: 10595
Pirb
Name: paired Ig-like receptor B
Synonyms: Gp91, Lilrb3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18733
Homologene: 134028
Rac1
Name: Rac family small GTPase 1
Synonyms: D5Ertd559e
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 19353
HGNC: HGNC:9801
Homologene: 69035
Slc39a8
Name: solute carrier family 39 (metal ion transporter), member 8
Synonyms: BIGM103, ZIP8, 4933419D20Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 67547
Homologene: 11155
Il20rb
Name: interleukin 20 receptor beta
Synonyms: LOC213208, Il20R2, Fndc6
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 213208
HGNC: HGNC:6004
Homologene: 86034
Pcmt1
Name: protein-L-isoaspartate (D-aspartate) O-methyltransferase 1
Synonyms: PIMT, protein carboxyl methyltransferase
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 18537
HGNC: HGNC:8728
Homologene: 135759
Zfp142
Name: zinc finger protein 142
Synonyms: 9330177B18Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 77264
Homologene: 3723
Trim33
Name: tripartite motif-containing 33
Synonyms: ectodermin, Tif1g, Ecto, 8030451N04Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 94093
Homologene: 9296
Il16
Name: interleukin 16
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 16170
HGNC: HGNC:5980
Homologene: 18157
Chst10
Name: carbohydrate sulfotransferase 10
Synonyms: ST, Hnk-1st
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 98388
Homologene: 21013
Itgae
Name: integrin alpha E, epithelial-associated
Synonyms: CD103, alpha-E1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16407
HGNC: HGNC:6147
Homologene: 113560
Fermt3
Name: fermitin family member 3
Synonyms: Kindlin-3, C79673
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 108101
VEGA: 19
Homologene: 12877
Lrrc37a
Name: leucine rich repeat containing 37A
Synonyms: LOC237954
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237954
Homologene: 138824
Peli2
Name: pellino 2
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 93834
VEGA: 14
HGNC: HGNC:8828
Homologene: 41431
Cfap65
Name: cilia and flagella associated protein 65
Synonyms: B230363K08Rik, Ccdc108
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 241116
Homologene: 28093
Pde4dip
Name: phosphodiesterase 4D interacting protein (myomegalin)
Synonyms: D3Bwg1078e, D130016K21Rik, 9430063L05Rik, Usmg4, 4732458A06Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 83679
Homologene: 66961
Pcnx1
Name: pecanex 1
Synonyms: Pcnx, 3526401J03Rik, 2900024E21Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 54604
VEGA: 12
Homologene: 40997
Flnc
Name: filamin C, gamma
Synonyms: 1110055E19Rik, actin binding protein 280, Fln2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 68794
HGNC: HGNC:3756
Homologene: 37481
Azin2
Name: antizyme inhibitor 2
Synonyms: Odcp, Adc, 4933429I20Rik, AZIN2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242669
Homologene: 62172
Or7e177
Name: olfactory receptor family 7 subfamily E member 177
Synonyms: GA_x6K02T2PVTD-14040245-14041204, MOR145-2, Olfr873
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258554
HGNC: HGNC:8396
Homologene: 115528
Tmf1
Name: TATA element modulatory factor 1
Synonyms: LOC232286, 7030402D04Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232286
Homologene: 133801
2210408I21Rik
Name: RIKEN cDNA 2210408I21 gene
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 72371
Homologene: 89234
Nacad
Name: NAC alpha domain containing
Synonyms: mKIAA0363
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 192950
Homologene: 135717
Yju2b
Name: YJU2 splicing factor homolog B
Synonyms: 4930527D15Rik, Ccdc130
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 67736
Homologene: 12183
Vmn1r43
Name: vomeronasal 1 receptor 43
Synonyms: V1ra5
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 113847
Homologene: 130651
Glyat
Name: glycine-N-acyltransferase
Synonyms: A330009E03Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 107146
Homologene: 64840
Or4f61
Name: olfactory receptor family 4 subfamily F member 61
Synonyms: Olfr1314, MOR245-2, GA_x6K02T2Q125-73139026-73138088
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258442
Homologene: 121538
Cd177
Name: CD177 antigen
Synonyms: 1190003K14Rik, Pdp3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 68891
Homologene: 49628
Or13a18
Name: olfactory receptor family 13 subfamily A member 18
Synonyms: MOR253-8, GA_x6K02T2PBJ9-42759973-42760905, IF5, ID12, IB7, Olfr46
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18345
Homologene: 110491
Or12k8
Name: olfactory receptor family 12 subfamily K member 8
Synonyms: MOR159-3, GA_x6K02T2NLDC-33777519-33776551, Olfr361
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258365
Homologene: 27142
Or1af1
Name: olfactory receptor family 1 subfamily AF member 1
Synonyms: Olfr366, MOR138-6, MOR138-5P, GA_x6K02T2NLDC-33902472-33903401
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 236509
Homologene: 114744
Fam47e
Name: family with sequence similarity 47, member E
Synonyms: Gm1381, LOC384198
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 384198
Homologene: 129958
Cyp2j13
Name: cytochrome P450, family 2, subfamily j, polypeptide 13
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230459
HGNC: HGNC:2634
Homologene: 138297
Slc38a8
Name: solute carrier family 38, member 8
Synonyms: LOC234788
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234788
Homologene: 19028
Vmn1r175
Name: vomeronasal 1 receptor 175
Synonyms: Gm6299
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 622222
Homologene: 128341
N4bp3
Name: NEDD4 binding protein 3
Synonyms: C330016O10Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 212706
Homologene: 17124
Ddn
Name: dendrin
Synonyms: LOC328602
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 13199
VEGA: 15
Homologene: 12816
Ankrd33
Name: ankyrin repeat domain 33
Synonyms: A930021G21Rik, Panky
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 208258
VEGA: 15
Homologene: 16992
Or7a40
Name: olfactory receptor family 7 subfamily A member 40
Synonyms: M12, MOR140-1, GA_x54KRFPKG5P-13123979-13123050, MTPCR15, Olfr19
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 18316
Homologene: 137402
Capza3
Name: capping actin protein of muscle Z-line subunit alpha 3
Synonyms: repro32, Tex8, cp alpha3, Cappa3, 510-4, Gsg3
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 12344
Homologene: 7253
Mall
Name: mal, T cell differentiation protein-like
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228576
HGNC: HGNC:6818
Homologene: 3965
Ighv2-3
Name: immunoglobulin heavy variable 2-3
Synonyms: Gm16948
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238412
Iglv1
Name: immunoglobulin lambda variable 1
Synonyms: 1810027O01Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 16142
Wdr49
Name: WD repeat domain 49
Synonyms: EG213248
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 213248
Homologene: 18714
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • C to A, chromosome 1 at 38,873,948 bp (GRCm38)
  • A to T, chromosome 1 at 74,572,303 bp (GRCm38)
  • A to G, chromosome 1 at 74,907,378 bp (GRCm38)
  • C to T, chromosome 2 at 30,346,660 bp (GRCm38)
  • C to A, chromosome 2 at 37,085,192 bp (GRCm38)
  • T to A, chromosome 2 at 37,220,269 bp (GRCm38)
  • T to C, chromosome 2 at 112,092,030 bp (GRCm38)
  • G to T, chromosome 2 at 127,729,831 bp (GRCm38)
  • C to T, chromosome 3 at 75,358,440 bp (GRCm38)
  • C to T, chromosome 3 at 97,694,891 bp (GRCm38)
  • C to T, chromosome 3 at 103,352,034 bp (GRCm38)
  • G to T, chromosome 3 at 135,886,927 bp (GRCm38)
  • G to T, chromosome 4 at 96,045,560 bp (GRCm38)
  • A to G, chromosome 4 at 128,959,824 bp (GRCm38)
  • G to C, chromosome 5 at 92,578,536 bp (GRCm38)
  • G to A, chromosome 5 at 143,527,888 bp (GRCm38)
  • A to G, chromosome 6 at 29,433,721 bp (GRCm38)
  • G to A, chromosome 6 at 89,869,895 bp (GRCm38)
  • C to T, chromosome 6 at 97,158,496 bp (GRCm38)
  • A to T, chromosome 6 at 140,041,986 bp (GRCm38)
  • A to T, chromosome 7 at 3,719,407 bp (GRCm38)
  • A to T, chromosome 7 at 23,809,083 bp (GRCm38)
  • A to G, chromosome 7 at 24,752,337 bp (GRCm38)
  • G to T, chromosome 7 at 83,673,065 bp (GRCm38)
  • C to T, chromosome 7 at 109,556,766 bp (GRCm38)
  • T to C, chromosome 7 at 140,611,026 bp (GRCm38)
  • T to C, chromosome 8 at 33,268,933 bp (GRCm38)
  • C to T, chromosome 8 at 84,261,771 bp (GRCm38)
  • C to A, chromosome 8 at 119,482,664 bp (GRCm38)
  • A to G, chromosome 9 at 20,300,365 bp (GRCm38)
  • G to A, chromosome 9 at 100,486,258 bp (GRCm38)
  • A to T, chromosome 10 at 7,649,053 bp (GRCm38)
  • G to T, chromosome 10 at 70,559,682 bp (GRCm38)
  • A to G, chromosome 10 at 111,273,048 bp (GRCm38)
  • T to C, chromosome 11 at 6,601,790 bp (GRCm38)
  • G to A, chromosome 11 at 8,451,142 bp (GRCm38)
  • C to T, chromosome 11 at 51,646,105 bp (GRCm38)
  • A to G, chromosome 11 at 73,125,356 bp (GRCm38)
  • A to G, chromosome 11 at 102,205,303 bp (GRCm38)
  • T to A, chromosome 11 at 103,501,726 bp (GRCm38)
  • T to A, chromosome 12 at 81,918,914 bp (GRCm38)
  • T to C, chromosome 12 at 113,611,464 bp (GRCm38)
  • A to G, chromosome 12 at 118,298,955 bp (GRCm38)
  • T to C, chromosome 13 at 77,316,447 bp (GRCm38)
  • T to A, chromosome 14 at 48,256,389 bp (GRCm38)
  • T to C, chromosome 15 at 98,807,696 bp (GRCm38)
  • T to C, chromosome 15 at 101,115,904 bp (GRCm38)
  • G to A, chromosome 16 at 16,673,606 bp (GRCm38)
  • A to G, chromosome 16 at 19,085,198 bp (GRCm38)
  • A to T, chromosome 16 at 36,620,913 bp (GRCm38)
  • T to G, chromosome 16 at 91,657,353 bp (GRCm38)
  • C to T, chromosome 19 at 7,002,251 bp (GRCm38)
  • A to G, chromosome 19 at 12,646,364 bp (GRCm38)
  • A to C, chromosome 19 at 41,649,412 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9595 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069388-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.