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Strain Name:
C57BL/6J-MtgxR9613Btlr/Mmmh
Stock Number:
069406-MU
Citation ID:
RRID:MMRRC_069406-MU
Other Names:
R9613 (G1)
Major Collection:

Strain Information

Kitl
Name: kit ligand
Synonyms: SF, stem cell factor, Steel factor, SLF, Mgf, Sl, Gb, grizzle-belly, Steel, SCF, Kitlg, blz
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 17311
HGNC: HGNC:6343
Homologene: 692
Septin4
Name: septin 4
Synonyms: cell division control-related protein 2b, Pnutl2, Bh5, septin H5, Gm11492, ARTS, Sept4
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18952
HGNC: HGNC:9165
Homologene: 6107
Dgat2
Name: diacylglycerol O-acyltransferase 2
Synonyms: 0610010B06Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 67800
Homologene: 23580
Macf1
Name: microtubule-actin crosslinking factor 1
Synonyms: Acf7, Aclp7, trabeculin alpha
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 11426
Homologene: 136191
Ewsr1
Name: Ewing sarcoma breakpoint region 1
Synonyms: Ews
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 14030
HGNC: HGNC:3508
Homologene: 134632
Plekha1
Name: pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
Synonyms: TAPP1, C920009D07Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 101476
Homologene: 11001
Ptpn12
Name: protein tyrosine phosphatase, non-receptor type 12
Synonyms: P19-PTP, PTP-PEST, PTP-P19
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 19248
HGNC: HGNC:9645
Homologene: 37691
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to C, chromosome 1 at 150,455,909 bp (GRCm38)
  • A to G, chromosome 2 at 24,958,205 bp (GRCm38)
  • A to G, chromosome 2 at 32,011,023 bp (GRCm38)
  • A to T, chromosome 2 at 59,901,480 bp (GRCm38)
  • A to G, chromosome 2 at 104,230,392 bp (GRCm38)
  • G to A, chromosome 3 at 26,878,665 bp (GRCm38)
  • G to A, chromosome 3 at 34,046,203 bp (GRCm38)
  • G to A, chromosome 3 at 95,851,619 bp (GRCm38)
  • G to A, chromosome 3 at 138,065,365 bp (GRCm38)
  • A to G, chromosome 4 at 6,272,587 bp (GRCm38)
  • A to G, chromosome 4 at 42,792,992 bp (GRCm38)
  • A to G, chromosome 4 at 123,526,495 bp (GRCm38)
  • C to A, chromosome 4 at 139,421,762 bp (GRCm38)
  • A to G, chromosome 5 at 20,998,623 bp (GRCm38)
  • A to T, chromosome 5 at 117,105,169 bp (GRCm38)
  • T to C, chromosome 6 at 82,652,118 bp (GRCm38)
  • G to A, chromosome 6 at 92,242,859 bp (GRCm38)
  • T to C, chromosome 6 at 123,638,116 bp (GRCm38)
  • G to A, chromosome 7 at 11,306,971 bp (GRCm38)
  • G to A, chromosome 7 at 21,053,121 bp (GRCm38)
  • A to G, chromosome 7 at 22,051,104 bp (GRCm38)
  • C to G, chromosome 7 at 99,182,485 bp (GRCm38)
  • T to C, chromosome 7 at 99,269,177 bp (GRCm38)
  • A to G, chromosome 7 at 99,767,329 bp (GRCm38)
  • C to A, chromosome 7 at 130,877,758 bp (GRCm38)
  • T to C, chromosome 7 at 143,644,846 bp (GRCm38)
  • C to A, chromosome 8 at 90,956,522 bp (GRCm38)
  • T to A, chromosome 8 at 105,380,988 bp (GRCm38)
  • A to T, chromosome 8 at 120,754,468 bp (GRCm38)
  • T to A, chromosome 9 at 7,075,769 bp (GRCm38)
  • G to A, chromosome 9 at 65,120,240 bp (GRCm38)
  • G to A, chromosome 9 at 105,739,202 bp (GRCm38)
  • C to A, chromosome 9 at 110,814,738 bp (GRCm38)
  • A to G, chromosome 10 at 100,080,919 bp (GRCm38)
  • A to G, chromosome 10 at 130,390,722 bp (GRCm38)
  • A to C, chromosome 11 at 5,078,924 bp (GRCm38)
  • A to T, chromosome 11 at 73,724,813 bp (GRCm38)
  • A to T, chromosome 11 at 87,578,997 bp (GRCm38)
  • A to G, chromosome 12 at 113,685,569 bp (GRCm38)
  • T to A, chromosome 13 at 55,639,936 bp (GRCm38)
  • T to C, chromosome 14 at 20,550,370 bp (GRCm38)
  • T to C, chromosome 14 at 34,731,563 bp (GRCm38)
  • T to A, chromosome 14 at 64,095,012 bp (GRCm38)
  • G to A, chromosome 15 at 79,634,083 bp (GRCm38)
  • T to C, chromosome 15 at 89,164,293 bp (GRCm38)
  • CTGTTG to CTG, chromosome 15 at 98,845,176 bp (GRCm38)
  • T to G, chromosome 16 at 5,249,408 bp (GRCm38)
  • A to G, chromosome 17 at 43,628,627 bp (GRCm38)
  • T to A, chromosome 18 at 44,168,145 bp (GRCm38)
  • A to C, chromosome 18 at 65,731,453 bp (GRCm38)
  • A to G, chromosome 19 at 8,977,654 bp (GRCm38)
  • C to A, chromosome 19 at 29,639,856 bp (GRCm38)
  • T to A, chromosome 19 at 34,942,534 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain GQC Summary
The MMRRC Centers have developed a Strain GQC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC strains. For more information on whether data may be available, or to request genotyping for a strain of interest, please contact MMRRC_GeneticQC@med.unc.edu. Older strains may not have this information available.
Suggested Control Mice
Littermates of all relevant genotypes.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9613 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.


Disclaimer: If MMRRC Strain Genetic Quality Control (GQC; based on MiniMUGA genotyping and analysis) has been completed for this strain, the information might differ from the genetic background information provided by the submitter. MiniMUGA genetic analysis is done on a strain’s tissue samples taken when archived by or ordered from the assigned MMRRC Center.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069406-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.