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Strain Name:
C57BL/6J-MtgxR9613Btlr/Mmmh
Stock Number:
069406-MU
Citation ID:
RRID:MMRRC_069406-MU
Other Names:
R9613 (G1)
Major Collection:

Strain Information

Kitl
Name: kit ligand
Synonyms: SF, stem cell factor, Steel factor, SLF, Mgf, Sl, Gb, grizzle-belly, Steel, SCF, blz, Kitlg
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 17311
HGNC: HGNC:6343
Homologene: 692
Septin4
Name: septin 4
Synonyms: cell division control-related protein 2b, Pnutl2, Bh5, septin H5, Gm11492, ARTS, Sept4
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18952
HGNC: HGNC:9165
Homologene: 6107
Dgat2
Name: diacylglycerol O-acyltransferase 2
Synonyms: 0610010B06Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 67800
Homologene: 23580
Macf1
Name: microtubule-actin crosslinking factor 1
Synonyms: Acf7, Aclp7, trabeculin alpha
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 11426
Homologene: 136191
Ewsr1
Name: Ewing sarcoma breakpoint region 1
Synonyms: Ews
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 14030
HGNC: HGNC:3508
Homologene: 134632
Plekha1
Name: pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
Synonyms: TAPP1, C920009D07Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 101476
Homologene: 11001
Ptpn12
Name: protein tyrosine phosphatase, non-receptor type 12
Synonyms: P19-PTP, PTP-PEST, PTP-P19
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 19248
HGNC: HGNC:9645
Homologene: 37691
Kif20b
Name: kinesin family member 20B
Synonyms: N-6 kinesin, C330014J10Rik, Kif20b, Mphosph1, 33cex, magoo
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 240641
VEGA: 19
HGNC: HGNC:7212
Homologene: 9418
Suds3
Name: suppressor of defective silencing 3 homolog (S. cerevisiae)
Synonyms: 2400003N08Rik, 2410008L21Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 71954
Homologene: 15906
Chd9
Name: chromodomain helicase DNA binding protein 9
Synonyms: 1810014J18Rik, AD013, A330063D19Rik, 9030205D12Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 109151
Homologene: 11844
Fxr1
Name: FMR1 autosomal homolog 1
Synonyms: 1110050J02Rik, Fxr1p, 9530073J07Rik, Fxr1h
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 14359
HGNC: HGNC:4023
Homologene: 3573
Nup214
Name: nucleoporin 214
Synonyms: D2H9S46E, CAN
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227720
HGNC: HGNC:8064
Homologene: 38008
Ddx46
Name: DEAD box helicase 46
Synonyms: 2200005K02Rik, 8430438J23Rik, DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 212880
VEGA: 13
Homologene: 5430
Wapl
Name: WAPL cohesin release factor
Synonyms: A530089A20Rik, Wapal
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 218914
Homologene: 41002
Prpf3
Name: pre-mRNA processing factor 3
Synonyms: 3632413F13Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 70767
Homologene: 3447
Cyp7a1
Name: cytochrome P450, family 7, subfamily a, polypeptide 1
Synonyms: cholesterol 7 alpha hydroxylase
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 13122
HGNC: HGNC:2651
Homologene: 30987
Trh
Name: thyrotropin releasing hormone
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 22044
Homologene: 5163
Plxnb2
Name: plexin B2
Synonyms: Debt, 1110007H23Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 140570
HGNC: HGNC:9104
Homologene: 66630
Ubr4
Name: ubiquitin protein ligase E3 component n-recognin 4
Synonyms: A930005E13Rik, LOC381562, D930005K06Rik, 1810009A16Rik, Zubr1, p600
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 69116
Homologene: 10804
Dync2h1
Name: dynein cytoplasmic 2 heavy chain 1
Synonyms: DHC1b, DHC2, 4432416O06Rik, D330044F14Rik, D030010H02Rik, Dnchc2, b2b414Clo, m407Asp, m152Asp
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 110350
HGNC: HGNC:2962
Homologene: 14468
Eef1g
Name: eukaryotic translation elongation factor 1 gamma
Synonyms: EF1G, 2610301D06Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 67160
HGNC: HGNC:3213
Homologene: 20363
Usp54
Name: ubiquitin specific peptidase 54
Synonyms: 4930429G18Rik, C030002J06Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 78787
Homologene: 90902
Baz2b
Name: bromodomain adjacent to zinc finger domain, 2B
Synonyms: D2Ertd794e, 5830435C13Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 407823
HGNC: HGNC:963
Homologene: 8394
Irf8
Name: interferon regulatory factor 8
Synonyms: IRF-8, ICSBP, Myls, Icsbp1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 15900
HGNC: HGNC:5358
Homologene: 1629
Plekhg4
Name: pleckstrin homology domain containing, family G (with RhoGef domain) member 4
Synonyms: 4931414L13Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 102075
Homologene: 18516
D430041D05Rik
Name: RIKEN cDNA D430041D05 gene
Synonyms: G2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241589
Homologene: 115928
Map6
Name: microtubule-associated protein 6
Synonyms: F-STOP, STOP, 2810411E12Rik, Mtap6
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 17760
HGNC: HGNC:6868
Homologene: 7850
Col6a6
Name: collagen, type VI, alpha 6
Synonyms: E330026B02Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 245026
Homologene: 18260
Prg4
Name: proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)
Synonyms: MSF, DOL54, lubricin, SZP
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 96875
HGNC: HGNC:9364
Homologene: 137352
Ermp1
Name: endoplasmic reticulum metallopeptidase 1
Synonyms: D19Ertd410e, D19Wsu12e, b2b2633Clo
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226090
Homologene: 121891
Vmn2r84
Name: vomeronasal 2, receptor 84
Synonyms: EG625068
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 625068
Homologene: 129606
Spata16
Name: spermatogenesis associated 16
Synonyms: spermatogenesis-related protein, Nyd-sp12, 4930503K02Rik, 4921511F01Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 70862
Homologene: 49974
Kmt2d
Name: lysine (K)-specific methyltransferase 2D
Synonyms: C430014K11Rik, Mll4, Mll2, bapa
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 381022
HGNC: HGNC:7133
Homologene: 86893
Fam227a
Name: family with sequence similarity 227, member A
Synonyms: 4933432B09Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 75729
Homologene: 123434
Vmn2r22
Name: vomeronasal 2, receptor 22
Synonyms: EG546913
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 546913
Homologene: 84037
Zscan4e
Name: zinc finger and SCAN domain containing 4E
Synonyms: EG665848
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 665848
Homologene: 85986
Zmynd19
Name: zinc finger, MYND domain containing 19
Synonyms: 2700064H14Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 67187
Homologene: 12093
Prss51
Name: serine protease 51
Synonyms: 1700007N14Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 100504162
Homologene: 131540
Oacyl
Name: O-acyltransferase like
Synonyms: 5330437I02Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 319888
Homologene: 129774
Vmn1r120
Name: vomeronasal 1 receptor 120
Synonyms: Gm5730
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 435953
Homologene: 104166
Or2at1
Name: olfactory receptor family 2 subfamily AT member 1
Synonyms: GA_x6K02T2PBJ9-2443810-2444775, MOR101-2, Olfr521
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258353
Homologene: 128108
Igdcc4
Name: immunoglobulin superfamily, DCC subclass, member 4
Synonyms: 9330155G14Rik, WI-18508, Nope, WI-16786
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 56741
VEGA: 9
Homologene: 10570
Tnfrsf22
Name: tumor necrosis factor receptor superfamily, member 22
Synonyms: Tnfrh2, 2810028K06Rik, SOBa, mDcTrailr2, C130035G06Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 79202
Homologene: 84848
Pole4
Name: polymerase (DNA-directed), epsilon 4 (p12 subunit)
Synonyms: 2400007P05Rik, 5830430F06Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 66979
Homologene: 41339
Prss44
Name: serine protease 44
Synonyms: TESSP4, 1700036D21Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 73336
Homologene: 135977
Spinkl
Name: serine protease inhibitor, Kazal type-like
Synonyms: 9530002K18Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 77424
VEGA: 18
Homologene: 128818
Eef2kmt
Name: eukaryotic elongation factor 2 lysine methyltransferase
Synonyms: 5730409G15Rik, Fam86
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 70511
Homologene: 45719
Ighv2-5
Name: immunoglobulin heavy variable 2-5
Synonyms: Gm16593
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 638605
Spata31f1e
Name: spermatogenesis associated 31 subfamily F member 1E
Synonyms: Gm12394
Type: Gene
Species: Mouse
Chromosome: 4
Or1e28-ps1
Name: olfactory receptor family 1 subfamily E member 28, pseudogene 1
Synonyms: GA_x6K02T2P1NL-3884648-3883708, MOR135-22, Olfr388-ps1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258182
Gm6176
Name: predicted gene 6176
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 620736
Homologene: 128656
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to C, chromosome 1 at 150,455,909 bp (GRCm38)
  • A to G, chromosome 2 at 24,958,205 bp (GRCm38)
  • A to G, chromosome 2 at 32,011,023 bp (GRCm38)
  • A to T, chromosome 2 at 59,901,480 bp (GRCm38)
  • A to G, chromosome 2 at 104,230,392 bp (GRCm38)
  • G to A, chromosome 3 at 26,878,665 bp (GRCm38)
  • G to A, chromosome 3 at 34,046,203 bp (GRCm38)
  • G to A, chromosome 3 at 95,851,619 bp (GRCm38)
  • G to A, chromosome 3 at 138,065,365 bp (GRCm38)
  • A to G, chromosome 4 at 6,272,587 bp (GRCm38)
  • A to G, chromosome 4 at 42,792,992 bp (GRCm38)
  • A to G, chromosome 4 at 123,526,495 bp (GRCm38)
  • C to A, chromosome 4 at 139,421,762 bp (GRCm38)
  • A to G, chromosome 5 at 20,998,623 bp (GRCm38)
  • A to T, chromosome 5 at 117,105,169 bp (GRCm38)
  • T to C, chromosome 6 at 82,652,118 bp (GRCm38)
  • G to A, chromosome 6 at 92,242,859 bp (GRCm38)
  • T to C, chromosome 6 at 123,638,116 bp (GRCm38)
  • G to A, chromosome 7 at 11,306,971 bp (GRCm38)
  • G to A, chromosome 7 at 21,053,121 bp (GRCm38)
  • A to G, chromosome 7 at 22,051,104 bp (GRCm38)
  • C to G, chromosome 7 at 99,182,485 bp (GRCm38)
  • T to C, chromosome 7 at 99,269,177 bp (GRCm38)
  • A to G, chromosome 7 at 99,767,329 bp (GRCm38)
  • C to A, chromosome 7 at 130,877,758 bp (GRCm38)
  • T to C, chromosome 7 at 143,644,846 bp (GRCm38)
  • C to A, chromosome 8 at 90,956,522 bp (GRCm38)
  • T to A, chromosome 8 at 105,380,988 bp (GRCm38)
  • A to T, chromosome 8 at 120,754,468 bp (GRCm38)
  • T to A, chromosome 9 at 7,075,769 bp (GRCm38)
  • G to A, chromosome 9 at 65,120,240 bp (GRCm38)
  • G to A, chromosome 9 at 105,739,202 bp (GRCm38)
  • C to A, chromosome 9 at 110,814,738 bp (GRCm38)
  • A to G, chromosome 10 at 100,080,919 bp (GRCm38)
  • A to G, chromosome 10 at 130,390,722 bp (GRCm38)
  • A to C, chromosome 11 at 5,078,924 bp (GRCm38)
  • A to T, chromosome 11 at 73,724,813 bp (GRCm38)
  • A to T, chromosome 11 at 87,578,997 bp (GRCm38)
  • A to G, chromosome 12 at 113,685,569 bp (GRCm38)
  • T to A, chromosome 13 at 55,639,936 bp (GRCm38)
  • T to C, chromosome 14 at 20,550,370 bp (GRCm38)
  • T to C, chromosome 14 at 34,731,563 bp (GRCm38)
  • T to A, chromosome 14 at 64,095,012 bp (GRCm38)
  • G to A, chromosome 15 at 79,634,083 bp (GRCm38)
  • T to C, chromosome 15 at 89,164,293 bp (GRCm38)
  • CTGTTG to CTG, chromosome 15 at 98,845,176 bp (GRCm38)
  • T to G, chromosome 16 at 5,249,408 bp (GRCm38)
  • A to G, chromosome 17 at 43,628,627 bp (GRCm38)
  • T to A, chromosome 18 at 44,168,145 bp (GRCm38)
  • A to C, chromosome 18 at 65,731,453 bp (GRCm38)
  • A to G, chromosome 19 at 8,977,654 bp (GRCm38)
  • C to A, chromosome 19 at 29,639,856 bp (GRCm38)
  • T to A, chromosome 19 at 34,942,534 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9613 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069406-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.