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Strain Name:
C57BL/6J-MtgxR9640Btlr/Mmmh
Stock Number:
069433-MU
Citation ID:
RRID:MMRRC_069433-MU
Other Names:
R9640 (G1)
Major Collection:

Strain Information

Pak1
Name: p21 (RAC1) activated kinase 1
Synonyms: PAK-1, Paka
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18479
HGNC: HGNC:8590
Homologene: 1936
Hbegf
Name: heparin-binding EGF-like growth factor
Synonyms: HB-EGF, Hegfl, Dtr
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 15200
VEGA: 18
HGNC: HGNC:3059
Homologene: 1466
Jam2
Name: junction adhesion molecule 2
Synonyms: 2410030G21Rik, JAM-2, VE-JAM, 2410167M24Rik, Jcam2
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 67374
Homologene: 10929
Bclaf1
Name: BCL2-associated transcription factor 1
Synonyms: 2700025J07Rik, 2810454G14Rik, 2610102K23Rik, 5730534O06Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 72567
Homologene: 8832
Abhd17c
Name: abhydrolase domain containing 17C
Synonyms: 2210412D01Rik, Fam108c
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 70178
Homologene: 26429
Sfmbt2
Name: Scm-like with four mbt domains 2
Synonyms: D330030P06Rik, D2Wsu23e
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 353282
Homologene: 82485
Lrba
Name: LPS-responsive beige-like anchor
Synonyms: Lba, D3Ertd775e
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 80877
HGNC: HGNC:1742
Homologene: 36205
Wwox
Name: WW domain-containing oxidoreductase
Synonyms: WOX1, 9030416C10Rik, 5330426P09Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 80707
Homologene: 56334
Hectd1
Name: HECT domain E3 ubiquitin protein ligase 1
Synonyms: A630086P08Rik, opm, b2b327Clo
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 207304
VEGA: 12
Homologene: 9115
Aspm
Name: abnormal spindle microtubule assembly
Synonyms: Sha1, Aspm, D330028K02Rik, MCPH5, Calmbp1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12316
Homologene: 7650
Mdn1
Name: midasin AAA ATPase 1
Synonyms: LOC213784, 4833432B22Rik, D4Abb1e
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100019
Homologene: 39689
Lrp6
Name: low density lipoprotein receptor-related protein 6
Synonyms: skam26Jus, Cd, ska26, skax26
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16974
HGNC: HGNC:6698
Homologene: 1747
Dusp5
Name: dual specificity phosphatase 5
Synonyms: LOC240672
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 240672
HGNC: HGNC:3071
Homologene: 3256
Gas2l3
Name: growth arrest-specific 2 like 3
Synonyms: LOC237436, 8430435B07Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 237436
VEGA: 10
Homologene: 18386
Atp6v1c1
Name: ATPase, H+ transporting, lysosomal V1 subunit C1
Synonyms: 1700025B18Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 66335
VEGA: 15
HGNC: HGNC:856
Homologene: 1281
Trim66
Name: tripartite motif-containing 66
Synonyms: D7H11orf29, Tif1d
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 330627
Homologene: 28044
Mib2
Name: mindbomb E3 ubiquitin protein ligase 2
Synonyms: 2210008I11Rik, Zzank1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 76580
Homologene: 16062
Frem1
Name: Fras1 related extracellular matrix protein 1
Synonyms: eyem02Jus, heb, QBRICK, crf11, eyes2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 329872
Homologene: 27049
Map3k1
Name: mitogen-activated protein kinase kinase kinase 1
Synonyms: MEKK1, Mekk
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 26401
HGNC: HGNC:6848
Homologene: 8056
Adam30
Name: a disintegrin and metallopeptidase domain 30
Synonyms: 4933424D07Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 71078
HGNC: HGNC:208
Homologene: 11038
Mapk8ip3
Name: mitogen-activated protein kinase 8 interacting protein 3
Synonyms: JNK-interacting protein 3, Jip3, JSAP1, JUN/SAPK-associated protein 1, JSAP1d, JSAP1c, JSAP1b, JSAP1a, c-Jun NH2-terminal kinase (JNK)/stress-activated protein kinase-associated protein 1, sunday driver 2, Syd2, D17Wsu15e
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 30957
HGNC: HGNC:6884
Homologene: 22790
Ccdc50
Name: coiled-coil domain containing 50
Synonyms: 5730448P06Rik, 2610529H08Rik, D16Bwg1543e
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 67501
Homologene: 69406
Grwd1
Name: glutamate-rich WD repeat containing 1
Synonyms: WDR28
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 101612
Homologene: 6644
Ndst4
Name: N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
Synonyms: 4930439H17Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 64580
Homologene: 11208
Zfp943
Name: zinc finger prtoein 943
Synonyms: 4930432O21Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 74670
Homologene: 134342
Lrp1b
Name: low density lipoprotein-related protein 1B
Synonyms: 9630004P12Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 94217
HGNC: HGNC:6693
Homologene: 56810
Lrp4
Name: low density lipoprotein receptor-related protein 4
Synonyms: 6430526J12Rik, mdig, Megf7
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228357
HGNC: HGNC:6696
Homologene: 17964
Cep162
Name: centrosomal protein 162
Synonyms: 4922501C03Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 382090
Homologene: 8930
Corin
Name: corin, serine peptidase
Synonyms: Lrp4
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 53419
Homologene: 4804
Rgs1
Name: regulator of G-protein signaling 1
Synonyms: BL34
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 50778
HGNC: HGNC:9991
Homologene: 2191
Cyp2c37
Name: cytochrome P450, family 2. subfamily c, polypeptide 37
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 13096
Homologene: 137231
Or5ae2
Name: olfactory receptor family 5 subfamily AE member 2
Synonyms: GA_x6K02T2NHDJ-11231385-11230438, MOR254-2, Olfr291
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258410
Homologene: 83130
H2-Q2
Name: histocompatibility 2, Q region locus 2
Synonyms: H-2Q2, Gm11132
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 15013
Homologene: 128352
Zfp932
Name: zinc finger protein 932
Synonyms: 2310001H12Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 69504
Homologene: 137770
H2-M1
Name: histocompatibility 2, M region locus 1
Synonyms: H-2M1, Mb1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224756
Homologene: 110792
Or1i2
Name: olfactory receptor family 1 subfamily I member 1
Synonyms: GA_x6K02T2QGN0-3196801-3197742, MOR128-4, MOR128-3, Olfr1357
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 257883
HGNC: HGNC:8207
Homologene: 72920
Slc6a21
Name: solute carrier family 6 member 21
Synonyms: 1700039E15Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 76713
Homologene: 66347
Spdef
Name: SAM pointed domain containing ets transcription factor
Synonyms: PDEF, Pse
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 30051
Homologene: 8231
Or8g20
Name: olfactory receptor family 8 subfamily G member 20
Synonyms: IB3, MOR171-5, GA_x6K02T2PVTD-33181773-33180838, Olfr44
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 18343
VEGA: 9
HGNC: HGNC:8484
Homologene: 133633
Rgl1
Name: ral guanine nucleotide dissociation stimulator,-like 1
Synonyms: Rgl
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 19731
Homologene: 9039
Sorcs2
Name: sortilin-related VPS10 domain containing receptor 2
Synonyms: VPS10 domain receptor protein
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 81840
Homologene: 56899
Kcnh8
Name: potassium voltage-gated channel, subfamily H (eag-related), member 8
Synonyms: Kv12.1, ELK1, C130090D05Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 211468
Homologene: 14332
Aadacl4fm4
Name: AADACL4 family member 4
Synonyms: LOC230890, Gm436
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230890
Homologene: 135765
Tas2r144
Name: taste receptor, type 2, member 144
Synonyms: mt2r33, Tas2r44
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 387515
Homologene: 47977
Zfp62
Name: zinc finger protein 62
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 22720
Homologene: 40686
Clip4
Name: CAP-GLY domain containing linker protein family, member 4
Synonyms: 1700074B05Rik, 5830409B12Rik, 4833417L20Rik, 1700024K14Rik, Rsnl2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 78785
VEGA: 17
Homologene: 11662
Ddx43
Name: DEAD box helicase 43
Synonyms: ENSMUSG00000070291, OTTMUSG00000019690, DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 100048658
Homologene: 56814
Or2l13
Name: olfactory receptor family 2 subfamily L member 13
Synonyms: GA_x54KRFPKG5P-15934912-15935850, MOR270-1, Olfr166
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 259071
Homologene: 88350
Mtss2
Name: MTSS I-BAR domain containing 2
Synonyms: ABBA, Mtss1l
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244654
Homologene: 70926
Vamp5
Name: vesicle-associated membrane protein 5
Synonyms: Camp
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 53620
Homologene: 4833
Fam114a1
Name: family with sequence similarity 114, member A1
Synonyms: 1190001N04Rik, 9130005N14Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 68303
Homologene: 12259
Matcap2
Name: microtubule associated tyrosine carboxypeptidase 2
Synonyms: 9530077C05Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 68283
VEGA: 9
Homologene: 19280
Zfp40
Name: zinc finger protein 40
Synonyms: NTfin12, Zfp-40
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 22700
Homologene: 136312
Ttc36
Name: tetratricopeptide repeat domain 36
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 192653
VEGA: 9
Homologene: 14626
Rnase2a
Name: ribonuclease, RNase A family, 2A (liver, eosinophil-derived neurotoxin)
Synonyms: Ear11
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 93726
VEGA: 14
Homologene: 121614
Ugt1a5
Name: UDP glucuronosyltransferase 1 family, polypeptide A5
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 394433
Homologene: 88621
Igkv11-125
Name: immunoglobulin kappa variable 11-125
Synonyms: ENSMUSG00000050218
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243428
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to G, chromosome 1 at 11,950,976 bp (GRCm38)
  • T to C, chromosome 1 at 88,166,376 bp (GRCm38)
  • T to A, chromosome 1 at 139,480,272 bp (GRCm38)
  • T to C, chromosome 1 at 144,245,378 bp (GRCm38)
  • T to C, chromosome 1 at 152,521,391 bp (GRCm38)
  • A to G, chromosome 2 at 10,579,183 bp (GRCm38)
  • T to C, chromosome 2 at 41,188,917 bp (GRCm38)
  • A to G, chromosome 2 at 91,485,951 bp (GRCm38)
  • T to A, chromosome 3 at 86,619,568 bp (GRCm38)
  • T to A, chromosome 3 at 98,162,304 bp (GRCm38)
  • C to A, chromosome 3 at 125,438,547 bp (GRCm38)
  • T to A, chromosome 4 at 32,754,539 bp (GRCm38)
  • T to A, chromosome 4 at 82,913,659 bp (GRCm38)
  • T to A, chromosome 4 at 144,686,239 bp (GRCm38)
  • T to C, chromosome 4 at 155,660,868 bp (GRCm38)
  • A to G, chromosome 5 at 30,921,959 bp (GRCm38)
  • G to T, chromosome 5 at 36,065,421 bp (GRCm38)
  • G to A, chromosome 5 at 65,009,051 bp (GRCm38)
  • C to T, chromosome 5 at 72,435,254 bp (GRCm38)
  • T to C, chromosome 5 at 110,009,198 bp (GRCm38)
  • A to G, chromosome 6 at 42,215,494 bp (GRCm38)
  • T to A, chromosome 6 at 67,913,799 bp (GRCm38)
  • G to A, chromosome 6 at 72,370,293 bp (GRCm38)
  • C to T, chromosome 6 at 134,464,451 bp (GRCm38)
  • A to T, chromosome 7 at 45,287,765 bp (GRCm38)
  • T to C, chromosome 7 at 45,827,879 bp (GRCm38)
  • A to T, chromosome 7 at 84,151,606 bp (GRCm38)
  • G to A, chromosome 7 at 84,856,906 bp (GRCm38)
  • T to A, chromosome 7 at 97,866,148 bp (GRCm38)
  • A to G, chromosome 7 at 109,475,618 bp (GRCm38)
  • T to C, chromosome 8 at 110,737,943 bp (GRCm38)
  • A to G, chromosome 8 at 114,439,800 bp (GRCm38)
  • A to T, chromosome 9 at 22,439,932 bp (GRCm38)
  • A to G, chromosome 9 at 39,485,100 bp (GRCm38)
  • A to T, chromosome 9 at 44,802,737 bp (GRCm38)
  • T to G, chromosome 9 at 78,396,107 bp (GRCm38)
  • A to G, chromosome 9 at 87,244,299 bp (GRCm38)
  • T to C, chromosome 10 at 20,325,807 bp (GRCm38)
  • G to C, chromosome 10 at 78,612,477 bp (GRCm38)
  • A to T, chromosome 10 at 89,430,912 bp (GRCm38)
  • A to G, chromosome 11 at 49,215,631 bp (GRCm38)
  • C to A, chromosome 12 at 51,748,414 bp (GRCm38)
  • A to T, chromosome 13 at 111,764,165 bp (GRCm38)
  • G to A, chromosome 14 at 51,255,660 bp (GRCm38)
  • C to T, chromosome 15 at 38,689,137 bp (GRCm38)
  • T to C, chromosome 16 at 14,618,725 bp (GRCm38)
  • A to T, chromosome 16 at 19,487,011 bp (GRCm38)
  • T to C, chromosome 16 at 27,406,711 bp (GRCm38)
  • A to T, chromosome 16 at 84,813,072 bp (GRCm38)
  • T to A, chromosome 17 at 21,990,918 bp (GRCm38)
  • T to C, chromosome 17 at 23,175,519 bp (GRCm38)
  • T to C, chromosome 17 at 24,936,673 bp (GRCm38)
  • G to T, chromosome 17 at 27,717,209 bp (GRCm38)
  • T to G, chromosome 17 at 35,343,230 bp (GRCm38)
  • G to T, chromosome 17 at 36,672,139 bp (GRCm38)
  • T to C, chromosome 17 at 52,878,061 bp (GRCm38)
  • C to T, chromosome 17 at 71,856,269 bp (GRCm38)
  • T to C, chromosome 18 at 36,507,590 bp (GRCm38)
  • T to A, chromosome 19 at 40,011,736 bp (GRCm38)
  • A to G, chromosome 19 at 53,537,620 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9640 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069433-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.