Strain Name:
C57BL/6J-MtgxR9673Btlr/Mmmh
Stock Number:
069466-MU
Citation ID:
RRID:MMRRC_069466-MU
Other Names:
R9673 (G1)
Major Collection:

Strain Information

Wee1
Name: WEE 1 homolog 1 (S. pombe)
Synonyms: Wee1A
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 22390
Homologene: 31152
Chd1
Name: chromodomain helicase DNA binding protein 1
Synonyms: 4930525N21Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 12648
HGNC: HGNC:1915
Homologene: 68174
Shmt1
Name: serine hydroxymethyltransferase 1 (soluble)
Synonyms: mshmt2, Shmt, mshmt, mshmt1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 20425
Homologene: 3074
Wfs1
Name: wolframin ER transmembrane glycoprotein
Synonyms: Wolfram syndrome 1 homolog (human), wolframin
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 22393
Homologene: 4380
Rangap1
Name: RAN GTPase activating protein 1
Synonyms: Fug1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 19387
VEGA: 15
HGNC: HGNC:9854
Homologene: 55700
Setd2
Name: SET domain containing 2
Synonyms: 4921524K10Rik, KMT3A
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235626
Homologene: 56493
Tbcd
Name: tubulin-specific chaperone d
Synonyms: A030005L14Rik, 2310057L06Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 108903
Homologene: 4368
Brwd1
Name: bromodomain and WD repeat domain containing 1
Synonyms: Wdr9, 5330419I02Rik, D530019K20Rik, repro5, G1-403-16
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 93871
Homologene: 23130
Ranbp2
Name: RAN binding protein 2
Synonyms: A430087B05Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 19386
VEGA: 10
Homologene: 87808
Copa
Name: coatomer protein complex subunit alpha
Synonyms: xenin
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12847
HGNC: HGNC:2230
Homologene: 3218
Ecpas
Name: Ecm29 proteasome adaptor and scaffold
Synonyms: AI314180
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230249
Homologene: 6056
Dmxl2
Name: Dmx-like 2
Synonyms: 6430411K14Rik, E130119P06Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235380
HGNC: HGNC:2938
Homologene: 41022
Lrrk2
Name: leucine-rich repeat kinase 2
Synonyms: cI-46, LOC381026, 9330188B09Rik, D630001M17Rik, 4921513O20Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 66725
Homologene: 18982
Tenm4
Name: teneurin transmembrane protein 4
Synonyms: Doc4, l7Rn3, ELM2, Odz4, l(7)-3Rn, Ten-m4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 23966
Homologene: 8034
Zfp277
Name: zinc finger protein 277
Synonyms: NIRF4, 2410017E24Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 246196
VEGA: 12
Homologene: 11087
Ap5z1
Name: adaptor-related protein complex 5, zeta 1 subunit
Synonyms: C330006K01Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231855
Homologene: 18213
Sbf1
Name: SET binding factor 1
Synonyms: 2610510A08Rik, Mtmr5, B230113C15Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 77980
Homologene: 84710
Nptx2
Name: neuronal pentraxin 2
Synonyms: np2, narp
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 53324
HGNC: HGNC:7953
Homologene: 1892
Nlrp3
Name: NLR family, pyrin domain containing 3
Synonyms: Cias1, Mmig1, NALP3, cryopyrin, Pypaf1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216799
Homologene: 3600
Hhip
Name: Hedgehog-interacting protein
Synonyms: Hip, Hip1, Hhip1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 15245
Homologene: 32469
Znrf2
Name: zinc and ring finger 2
Synonyms: D6Ertd365e, 1190002C14Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 387524
Homologene: 15668
Krr1
Name: KRR1, small subunit (SSU) processome component, homolog (yeast)
Synonyms: 2610511F02Rik, Hrb2, D10Ertd773e
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 52705
HGNC: HGNC:5176
Homologene: 5114
Mtmr4
Name: myotubularin related protein 4
Synonyms: ZFYVE11, ESTM44, FYVE-DSP2, FYVE zinc finger phosphatase
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 170749
HGNC: HGNC:7452
Homologene: 3440
Cep95
Name: centrosomal protein 95
Synonyms: Ccdc45, F630025I20Rik, 4732496G21Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 320162
Homologene: 16297
Zbtb11
Name: zinc finger and BTB domain containing 11
Synonyms: ZNF-U69274, 9230110G02Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 271377
Homologene: 8678
Dnph1
Name: 2'-deoxynucleoside 5'-phosphate N-hydrolase 1
Synonyms: Rcl, c-Myc-responsive, BC048355
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 381101
VEGA: 17
Homologene: 4704
Zfp874a
Name: zinc finger protein 874a
Synonyms: Rslcan15, C330011K17Rik, Zfp874
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 238692
Homologene: 135597
Tmem204
Name: transmembrane protein 204
Synonyms: Clp24
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 407831
Homologene: 36419
Zp2
Name: zona pellucida glycoprotein 2
Synonyms: Zp-2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 22787
Homologene: 48194
Skor2
Name: SKI family transcriptional corepressor 2
Synonyms: Fussel18, Corl2, Gm7348
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 664805
VEGA: 18
Homologene: 64797
Peg10
Name: paternally expressed 10
Synonyms: Rtl2, MEF3L, MyEF-3, Mar2, MyEF-3 like, Edr, HB-1, Mart2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 170676
Homologene: 116067
Chkb
Name: choline kinase beta
Synonyms: CK/EK-beta, Chkl, Chetk
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 12651
HGNC: HGNC:1938
Homologene: 88718
Ttn
Name: titin
Synonyms: connectin, shru, D330041I19Rik, 2310057K23Rik, mdm, D830007G01Rik, 2310074I15Rik, 1100001C23Rik, 2310036G12Rik, L56
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Creb3
Name: cAMP responsive element binding protein 3
Synonyms: Luman, LZIP-1, LZIP-2, LZIP
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 12913
HGNC: HGNC:2347
Homologene: 31375
Pclo
Name: piccolo (presynaptic cytomatrix protein)
Synonyms: Pico, Acz
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 26875
Homologene: 69111
Celsr1
Name: cadherin, EGF LAG seven-pass G-type receptor 1
Synonyms: Scy, Crsh, Adgrc1, crash
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 12614
VEGA: 15
HGNC: HGNC:1850
Homologene: 7665
Dnah11
Name: dynein, axonemal, heavy chain 11
Synonyms: b2b1289Clo, b2b1203Clo, Dnahc11, b2b1279Clo, avc4, b2b1727Clo, b2b598Clo, lrd
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 13411
HGNC: HGNC:2942
Homologene: 2801
Cdh8
Name: cadherin 8
Synonyms: cad8
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 12564
HGNC: HGNC:1767
Homologene: 55604
Pkhd1l1
Name: polycystic kidney and hepatic disease 1-like 1
Synonyms: fibrocystin L, PKHDL1, D86 mRNA
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 192190
Homologene: 16332
Proser3
Name: proline and serine rich 3
Synonyms: BC053749
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 333193
Homologene: 116064
Tesk1
Name: testis specific protein kinase 1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 21754
Homologene: 4577
Magi2
Name: membrane associated guanylate kinase, WW and PDZ domain containing 2
Synonyms: Acvrinp1, Magi-2, S-SCAM
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 50791
Homologene: 8189
Neb
Name: nebulin
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17996
HGNC: HGNC:7720
Homologene: 136285
Slc22a29
Name: solute carrier family 22. member 29
Synonyms: D630002G06Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 236293
Homologene: 77136
Ryr3
Name: ryanodine receptor 3
Synonyms: calcium release channel isoform 3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 20192
Homologene: 68151
Fcgbpl1
Name: Fc fragment of IgG binding protein like 1
Synonyms: 9530053A07Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 319482
Homologene: 130055
Wdpcp
Name: WD repeat containing planar cell polarity effector
Synonyms: homoloc-13, AV249152
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216560
Homologene: 9299
Rp1
Name: retinitis pigmentosa 1 (human)
Synonyms: Dcdc3, mG145, oxygen-regulated protein 1, Orp1, Rp1h
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 19888
Homologene: 4564
Vmn2r77
Name: vomeronasal 2, receptor 77
Synonyms: EG546983
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 546983
Homologene: 115466
Nhsl1
Name: NHS like 1
Synonyms: D10Bwg0940e, A630035H13Rik, 5730409E15Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 215819
Homologene: 27834
Ino80c
Name: INO80 complex subunit C
Synonyms: D030070L09Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225280
Homologene: 45426
Jag2
Name: jagged 2
Synonyms: Serh, D12Ggc2e
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 16450
VEGA: 12
HGNC: HGNC:6189
Homologene: 1677
Kcnma1
Name: potassium large conductance calcium-activated channel, subfamily M, alpha member 1
Synonyms: mSlo1, Slo, 5730414M22Rik, BK channel alpha subunit, BKCa, MaxiK, Slo1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 16531
HGNC: HGNC:6284
Homologene: 1693
Fam76a
Name: family with sequence similarity 76, member A
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230789
Homologene: 27071
Tcaf1
Name: TRPM8 channel-associated factor 1
Synonyms: 3321401G04Rik, 2810407D09Rik, A230020K05Rik, Fam115a
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 77574
Homologene: 8815
Csmd2
Name: CUB and Sushi multiple domains 2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 329942
Homologene: 89034
Atrnl1
Name: attractin like 1
Synonyms: Alp
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226255
VEGA: 19
Homologene: 45809
4930568D16Rik
Name: RIKEN cDNA 4930568D16 gene
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 75859
Homologene: 86865
Atxn1
Name: ataxin 1
Synonyms: Atx1, Sca1, 2900016G23Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 20238
VEGA: 13
Homologene: 281
Lilrb4b
Name: leukocyte immunoglobulin-like receptor, subfamily B, member 4B
Synonyms: gp49, Lilr4b, Gp49a
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 14727
HGNC: HGNC:6608
Homologene: 86756
Lats1
Name: large tumor suppressor
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 16798
VEGA: 10
HGNC: HGNC:6514
Homologene: 55843
Fam186a
Name: family with sequence similarity 186, member A
Synonyms: 1700030F18Rik, LOC380973
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 72277
Osm
Name: oncostatin M
Synonyms: OncoM
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18413
HGNC: HGNC:8506
Homologene: 10741
Pdlim3
Name: PDZ and LIM domain 3
Synonyms: ALP
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 53318
Homologene: 75063
Pgm2
Name: phosphoglucomutase 2
Synonyms: Pgm-1, Pgm1, 3230402E02Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 66681
HGNC: HGNC:8906
Homologene: 6693
Gabrg3
Name: gamma-aminobutyric acid type A receptor, subunit gamma 3
Synonyms: Gabrg-3, B230362M20Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 14407
HGNC: HGNC:4088
Homologene: 22444
Vmn1r70
Name: vomeronasal 1 receptor 70
Synonyms: V1rl1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 171262
Homologene: 74361
Cxcr1
Name: C-X-C motif chemokine receptor 1
Synonyms: Il8ra
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 227288
HGNC: HGNC:6026
Homologene: 68074
Ifi209
Name: interferon activated gene 209
Synonyms: Ifix, Pyhin1, Pyhin-1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 236312
HGNC: HGNC:5395
Homologene: 115929
Bud23
Name: BUD23, rRNA methyltransferase and ribosome maturation factor
Synonyms: 1110003N24Rik, Wbscr22
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 66138
Homologene: 5486
Speer1g
Name: spermatogenesis associated glutamate (E)-rich protein 1G
Synonyms: Gm8879
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 667916
G6pc1
Name: glucose-6-phosphatase catalytic subunit 1
Synonyms: G6pt, G6pc, Glc-6-Pase, G6Pase, Glc-6-Pase-alpha
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 14377
HGNC: HGNC:4056
Homologene: 20079
Frrs1l
Name: ferric-chelate reductase 1 like
Synonyms: 6430704M03Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230235
HGNC: HGNC:1362
Homologene: 87703
Esp16
Name: exocrine gland secreted peptide 16
Synonyms: Gm4345
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 100043300
Cyct
Name: cytochrome c, testis
Synonyms: T-Cc
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 13067
Homologene: 129551
Pcdha12
Name: protocadherin alpha 12
Synonyms: Cnr5, Crnr5, Pcdha13
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 192164
HGNC: HGNC:8667
Homologene: 135870
Tmem176a
Name: transmembrane protein 176A
Synonyms: 0610011I04Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 66058
Homologene: 10224
Sord
Name: sorbitol dehydrogenase
Synonyms: Sdh-1, Sodh-1, Sdh1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 20322
Homologene: 56080
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • G to A, chromosome 1 at 4,267,569 bp (GRCm38)
  • T to C, chromosome 1 at 74,191,915 bp (GRCm38)
  • A to G, chromosome 1 at 172,118,081 bp (GRCm38)
  • T to C, chromosome 1 at 173,642,766 bp (GRCm38)
  • T to C, chromosome 2 at 35,354,387 bp (GRCm38)
  • C to T, chromosome 2 at 52,243,841 bp (GRCm38)
  • A to T, chromosome 2 at 76,354,179 bp (GRCm38)
  • T to A, chromosome 2 at 76,742,261 bp (GRCm38)
  • G to A, chromosome 2 at 112,656,538 bp (GRCm38)
  • C to T, chromosome 2 at 122,260,231 bp (GRCm38)
  • A to G, chromosome 4 at 43,444,574 bp (GRCm38)
  • G to T, chromosome 4 at 43,563,191 bp (GRCm38)
  • A to C, chromosome 4 at 56,990,191 bp (GRCm38)
  • T to C, chromosome 4 at 58,822,060 bp (GRCm38)
  • T to A, chromosome 4 at 128,414,269 bp (GRCm38)
  • C to A, chromosome 4 at 132,901,246 bp (GRCm38)
  • T to A, chromosome 5 at 11,129,023 bp (GRCm38)
  • A to G, chromosome 5 at 14,858,744 bp (GRCm38)
  • A to G, chromosome 5 at 20,465,584 bp (GRCm38)
  • A to G, chromosome 5 at 36,967,769 bp (GRCm38)
  • T to A, chromosome 5 at 64,116,328 bp (GRCm38)
  • T to C, chromosome 5 at 135,053,717 bp (GRCm38)
  • T to C, chromosome 5 at 142,477,358 bp (GRCm38)
  • T to C, chromosome 5 at 144,555,349 bp (GRCm38)
  • GC to GCTCC, chromosome 6 at 4,756,452 bp (GRCm38)
  • G to A, chromosome 6 at 42,686,874 bp (GRCm38)
  • G to A, chromosome 6 at 48,844,018 bp (GRCm38)
  • A to T, chromosome 6 at 54,863,993 bp (GRCm38)
  • T to A, chromosome 7 at 10,634,437 bp (GRCm38)
  • A to G, chromosome 7 at 28,156,619 bp (GRCm38)
  • T to G, chromosome 7 at 30,549,105 bp (GRCm38)
  • T to A, chromosome 7 at 57,323,674 bp (GRCm38)
  • T to C, chromosome 7 at 86,800,963 bp (GRCm38)
  • A to T, chromosome 7 at 96,867,989 bp (GRCm38)
  • C to T, chromosome 7 at 110,126,003 bp (GRCm38)
  • T to A, chromosome 7 at 120,134,015 bp (GRCm38)
  • C to T, chromosome 8 at 45,915,158 bp (GRCm38)
  • T to A, chromosome 8 at 79,992,479 bp (GRCm38)
  • T to A, chromosome 8 at 99,030,735 bp (GRCm38)
  • G to T, chromosome 9 at 54,387,556 bp (GRCm38)
  • A to G, chromosome 9 at 110,549,070 bp (GRCm38)
  • T to G, chromosome 10 at 7,712,623 bp (GRCm38)
  • T to A, chromosome 10 at 18,526,917 bp (GRCm38)
  • T to C, chromosome 10 at 51,481,657 bp (GRCm38)
  • C to A, chromosome 10 at 58,465,141 bp (GRCm38)
  • G to A, chromosome 10 at 111,983,058 bp (GRCm38)
  • A to G, chromosome 11 at 4,239,926 bp (GRCm38)
  • A to G, chromosome 11 at 21,721,285 bp (GRCm38)
  • T to A, chromosome 11 at 59,549,322 bp (GRCm38)
  • A to G, chromosome 11 at 60,801,943 bp (GRCm38)
  • A to G, chromosome 11 at 87,612,312 bp (GRCm38)
  • T to C, chromosome 11 at 87,614,090 bp (GRCm38)
  • T to C, chromosome 11 at 101,376,554 bp (GRCm38)
  • C to A, chromosome 11 at 106,812,496 bp (GRCm38)
  • T to C, chromosome 11 at 121,573,821 bp (GRCm38)
  • A to T, chromosome 12 at 40,320,612 bp (GRCm38)
  • G to T, chromosome 12 at 112,911,796 bp (GRCm38)
  • A to G, chromosome 12 at 118,018,778 bp (GRCm38)
  • T to C, chromosome 13 at 45,557,146 bp (GRCm38)
  • G to T, chromosome 13 at 62,370,155 bp (GRCm38)
  • C to A, chromosome 13 at 67,443,037 bp (GRCm38)
  • A to C, chromosome 14 at 23,508,055 bp (GRCm38)
  • T to C, chromosome 15 at 44,523,505 bp (GRCm38)
  • T to C, chromosome 15 at 81,706,436 bp (GRCm38)
  • G to T, chromosome 15 at 86,033,085 bp (GRCm38)
  • C to T, chromosome 15 at 89,295,472 bp (GRCm38)
  • C to G, chromosome 15 at 89,429,425 bp (GRCm38)
  • T to A, chromosome 15 at 91,765,681 bp (GRCm38)
  • T to C, chromosome 15 at 99,943,143 bp (GRCm38)
  • A to G, chromosome 16 at 56,006,973 bp (GRCm38)
  • T to G, chromosome 16 at 96,011,896 bp (GRCm38)
  • A to G, chromosome 17 at 15,768,761 bp (GRCm38)
  • A to T, chromosome 17 at 25,080,269 bp (GRCm38)
  • T to A, chromosome 17 at 39,537,840 bp (GRCm38)
  • G to A, chromosome 17 at 46,498,975 bp (GRCm38)
  • C to T, chromosome 18 at 24,121,799 bp (GRCm38)
  • T to C, chromosome 18 at 37,022,181 bp (GRCm38)
  • C to T, chromosome 18 at 76,858,681 bp (GRCm38)
  • T to C, chromosome 19 at 8,162,740 bp (GRCm38)
  • A to G, chromosome 19 at 57,611,354 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9673 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069466-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.