Strain Name:
C57BL/6J-MtgxR9705Btlr/Mmmh
Stock Number:
069952-MU
Citation ID:
RRID:MMRRC_069952-MU
Other Names:
R9705 (G1)
Major Collection:

Strain Information

Cemip2
Name: cell migration inducing hyaluronidase 2
Synonyms: 3110012M15Rik, Tmem2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 83921
VEGA: 19
Homologene: 75008
B4galt1
Name: UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
Synonyms: b1,4-Galactosyltransferase I, B-1,4-GalT1, beta 1,4-Galactosyltransferase I, Ggtb2, beta-1,4-GalT1, GalT, Ggtb
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 14595
HGNC: HGNC:924
Homologene: 20378
Pck1
Name: phosphoenolpyruvate carboxykinase 1, cytosolic
Synonyms: PEPCK, Pck-1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 18534
HGNC: HGNC:8724
Homologene: 1944
Drd5
Name: dopamine receptor D5
Synonyms: Gpcr1, Drd1b, DRD1b, D5R, Drd-5
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 13492
HGNC: HGNC:3026
Homologene: 20216
Syt3
Name: synaptotagmin III
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 20981
Homologene: 9617
Neurl4
Name: neuralized E3 ubiquitin protein ligase 4
Synonyms: 0610025P10Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216860
Homologene: 13029
Aff1
Name: AF4/FMR2 family, member 1
Synonyms: Rob, Mllt2h, 9630032B01Rik, Af4
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 17355
HGNC: HGNC:7135
Homologene: 4340
Tacc2
Name: transforming, acidic coiled-coil containing protein 2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 57752
Homologene: 5087
Pi4ka
Name: phosphatidylinositol 4-kinase alpha
Synonyms: Pik4ca
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224020
HGNC: HGNC:8983
Homologene: 11171
Hsd17b4
Name: hydroxysteroid (17-beta) dehydrogenase 4
Synonyms: MFP2, Mfp-2, 17[b]-HSD, perMFE-2, multifunctional protein 2, MFE-2, D-bifunctional protein
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 15488
HGNC: HGNC:5213
Homologene: 358
Ccar2
Name: cell cycle activator and apoptosis regulator 2
Synonyms: 2610301G19Rik, Dbc1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 219158
VEGA: 14
Homologene: 10910
Brap
Name: BRCA1 associated protein
Synonyms: 3010002G07Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 72399
HGNC: HGNC:1099
Homologene: 4926
Mphosph10
Name: M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
Synonyms: 5730405D16Rik, 2810453H10Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 67973
HGNC: HGNC:7213
Homologene: 134741
Snapc1
Name: small nuclear RNA activating complex, polypeptide 1
Synonyms: 9630050P21Rik, 2700033G17Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 75627
VEGA: 12
Homologene: 2317
Pgm3
Name: phosphoglucomutase 3
Synonyms: 2810473H05Rik, Pgm-3, GlcNAc-P mutase
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 109785
HGNC: HGNC:8907
Homologene: 9205
Jph3
Name: junctophilin 3
Synonyms: JP-3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 57340
Homologene: 10762
C1qtnf6
Name: C1q and tumor necrosis factor related protein 6
Synonyms: CTRP6, 2810036M19Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 72709
Homologene: 12481
Hectd4
Name: HECT domain E3 ubiquitin protein ligase 4
Synonyms: Gm15800
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 269700
Homologene: 28297
Col4a4
Name: collagen, type IV, alpha 4
Synonyms: [a]4(IV), E130010M05Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12829
HGNC: HGNC:2206
Homologene: 20071
Ubb
Name: ubiquitin B
Synonyms: Ubb2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 22187
Homologene: 74981
Ptpn13
Name: protein tyrosine phosphatase, non-receptor type 13
Synonyms: PTPL1, PTP-BL, Ptpri
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 19249
HGNC: HGNC:9646
Homologene: 7909
Rusc2
Name: RUN and SH3 domain containing 2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100213
Homologene: 18967
Dnah11
Name: dynein, axonemal, heavy chain 11
Synonyms: b2b1203Clo, Dnahc11, avc4, b2b1289Clo, b2b1279Clo, lrd, b2b598Clo, b2b1727Clo
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 13411
HGNC: HGNC:2942
Homologene: 2801
Cul9
Name: cullin 9
Synonyms: Parc, 1810035I07Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 78309
Homologene: 56696
Fsip2
Name: fibrous sheath-interacting protein 2
Synonyms: OTTMUSG00000013335
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241516
Homologene: 110349
H2-M10.6
Name: histocompatibility 2, M region locus 10.6
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 399549
Homologene: 117973
Ephb6
Name: Eph receptor B6
Synonyms: Mep, Cekl
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 13848
HGNC: HGNC:3396
Homologene: 20940
Synpo2l
Name: synaptopodin 2-like
Synonyms: Chap, 1110054M18Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 68760
Homologene: 23499
Ngef
Name: neuronal guanine nucleotide exchange factor
Synonyms: ephexin, Tims2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 53972
HGNC: HGNC:7807
Homologene: 75120
Inpp4b
Name: inositol polyphosphate-4-phosphatase, type II
Synonyms: E130107I17Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234515
HGNC: HGNC:6075
Homologene: 20832
Vmn2r90
Name: vomeronasal 2, receptor 90
Synonyms: EG626942
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 626942
Zfp27
Name: zinc finger protein 27
Synonyms: Zfp-27, mkr-4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 22689
Homologene: 81823
Styk1
Name: serine/threonine/tyrosine kinase 1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243659
Homologene: 49545
Cyp3a59
Name: cytochrome P450, family 3, subfamily a, polypeptide 59
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100041449
Homologene: 135775
Rars2
Name: arginyl-tRNA synthetase 2, mitochondrial
Synonyms: PRO1992, Rarsl, 1500002I10Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 109093
Homologene: 5707
H2ac1
Name: H2A clustered histone 1
Synonyms: Hist1h2aa
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 319163
Homologene: 137631
Fam83e
Name: family with sequence similarity 83, member E
Synonyms: 4930403C10Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 73813
Homologene: 9791
Cdh15
Name: cadherin 15
Synonyms: M cadherin, Mcad, Cdh14
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 12555
HGNC: HGNC:1754
Homologene: 3622
A830018L16Rik
Name: RIKEN cDNA A830018L16 gene
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 320492
Homologene: 14194
Hoxc9
Name: homeobox C9
Synonyms: Hox-3.2
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 15427
HGNC: HGNC:5130
Homologene: 130558
Or1j10
Name: olfactory receptor family 1 subfamily J member 10
Synonyms: MOR136-5, GA_x6K02T2NLDC-33070879-33071799, Olfr338
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258949
Homologene: 133647
Or56a3b
Name: olfactory receptor family 56 subfamily A member 3B
Synonyms: GA_x6K02T2PBJ9-7750163-7751110, MOR40-14, Olfr681
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 404318
Homologene: 81538
Trp53tg5
Name: transformation related protein 53 target 5
Synonyms: 1700126L10Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 73603
Homologene: 49386
Krt79
Name: keratin 79
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223917
Homologene: 89169
Mrm2
Name: mitochondrial rRNA methyltransferase 2
Synonyms: Ftsj2, 2310037B18Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 68017
Homologene: 5907
Spag8
Name: sperm associated antigen 8
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 433700
Homologene: 8250
Odam
Name: odontogenic, ameloblast asssociated
Synonyms: 2310011G06Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 69592
Homologene: 49511
Ramp2
Name: receptor (calcitonin) activity modifying protein 2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 54409
HGNC: HGNC:9844
Homologene: 4274
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • C to T, chromosome 1 at 11,518,689 bp (GRCm38)
  • G to A, chromosome 1 at 82,487,592 bp (GRCm38)
  • G to A, chromosome 1 at 87,503,288 bp (GRCm38)
  • A to G, chromosome 2 at 36,376,950 bp (GRCm38)
  • A to G, chromosome 2 at 82,993,290 bp (GRCm38)
  • T to C, chromosome 2 at 164,471,288 bp (GRCm38)
  • T to A, chromosome 2 at 173,158,377 bp (GRCm38)
  • A to T, chromosome 4 at 34,646,561 bp (GRCm38)
  • T to C, chromosome 4 at 40,853,474 bp (GRCm38)
  • A to C, chromosome 4 at 43,424,936 bp (GRCm38)
  • G to A, chromosome 4 at 43,652,366 bp (GRCm38)
  • T to C, chromosome 5 at 38,320,684 bp (GRCm38)
  • T to A, chromosome 5 at 87,889,369 bp (GRCm38)
  • T to C, chromosome 5 at 103,533,355 bp (GRCm38)
  • T to G, chromosome 5 at 103,784,410 bp (GRCm38)
  • A to T, chromosome 5 at 121,310,681 bp (GRCm38)
  • A to G, chromosome 5 at 121,663,310 bp (GRCm38)
  • G to A, chromosome 5 at 140,331,235 bp (GRCm38)
  • A to G, chromosome 5 at 146,096,310 bp (GRCm38)
  • G to A, chromosome 6 at 41,619,781 bp (GRCm38)
  • CTCTTCATGATTTTCTT to CTCTT, chromosome 6 at 131,301,649 bp (GRCm38)
  • C to A, chromosome 7 at 29,895,917 bp (GRCm38)
  • A to G, chromosome 7 at 44,395,801 bp (GRCm38)
  • G to A, chromosome 7 at 45,722,497 bp (GRCm38)
  • T to C, chromosome 7 at 64,377,283 bp (GRCm38)
  • T to A, chromosome 7 at 105,121,634 bp (GRCm38)
  • A to G, chromosome 7 at 130,759,288 bp (GRCm38)
  • T to C, chromosome 8 at 82,046,261 bp (GRCm38)
  • C to T, chromosome 8 at 121,782,174 bp (GRCm38)
  • C to A, chromosome 8 at 122,864,285 bp (GRCm38)
  • A to G, chromosome 9 at 86,555,361 bp (GRCm38)
  • A to G, chromosome 11 at 62,552,549 bp (GRCm38)
  • A to T, chromosome 11 at 69,908,853 bp (GRCm38)
  • T to A, chromosome 11 at 101,246,543 bp (GRCm38)
  • G to T, chromosome 12 at 73,968,376 bp (GRCm38)
  • A to C, chromosome 12 at 118,131,035 bp (GRCm38)
  • A to G, chromosome 13 at 23,934,745 bp (GRCm38)
  • C to T, chromosome 14 at 20,660,921 bp (GRCm38)
  • C to A, chromosome 14 at 70,142,934 bp (GRCm38)
  • T to A, chromosome 15 at 78,527,293 bp (GRCm38)
  • T to G, chromosome 15 at 101,930,761 bp (GRCm38)
  • T to A, chromosome 15 at 102,981,930 bp (GRCm38)
  • A to T, chromosome 16 at 17,281,951 bp (GRCm38)
  • A to G, chromosome 17 at 17,712,777 bp (GRCm38)
  • A to G, chromosome 17 at 36,812,750 bp (GRCm38)
  • T to G, chromosome 17 at 46,543,300 bp (GRCm38)
  • A to C, chromosome 18 at 50,191,724 bp (GRCm38)
  • G to A, chromosome 19 at 21,807,424 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9705 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069952-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.