Strain Name:
C57BL/6J-MtgxR9718Btlr/Mmmh
Stock Number:
069965-MU
Citation ID:
RRID:MMRRC_069965-MU
Other Names:
R9718 (G1)
Major Collection:

Strain Information

Shprh
Name: SNF2 histone linker PHD RING helicase
Synonyms: 2610103K11Rik, D230017O13Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 268281
Homologene: 6489
Acvr1c
Name: activin A receptor, type IC
Synonyms: Alk-7, ALK7
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 269275
Homologene: 26724
Omd
Name: osteomodulin
Synonyms: OSAD, osteoadherin, SLRR2C
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 27047
VEGA: 13
HGNC: HGNC:8134
Homologene: 3677
Tjp2
Name: tight junction protein 2
Synonyms: ZO-2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 21873
VEGA: 19
Homologene: 3541
Strn4
Name: striatin, calmodulin binding protein 4
Synonyms: ZIN, zinedin
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 97387
Homologene: 8378
L3mbtl2
Name: L3MBTL2 polycomb repressive complex 1 subunit
Synonyms: 4732493N06Rik, m4mbt
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 214669
Homologene: 12882
Ckap5
Name: cytoskeleton associated protein 5
Synonyms: 3110043H24Rik, 4930432B04Rik, D730027C18Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 75786
Homologene: 8844
Map4
Name: microtubule-associated protein 4
Synonyms: MAP 4, Mtap4
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 17758
HGNC: HGNC:6862
Homologene: 1780
Sfswap
Name: splicing factor SWAP
Synonyms: 1190005N23Rik, Sfrs8, 6330437E22Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231769
Homologene: 134548
Senp7
Name: SUMO1/sentrin specific peptidase 7
Synonyms: 2410152H17Rik, 2900036C23Rik, 2810413I22Rik, 6030449K19Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 66315
Homologene: 10778
Chd9
Name: chromodomain helicase DNA binding protein 9
Synonyms: 9030205D12Rik, 1810014J18Rik, AD013, A330063D19Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 109151
Homologene: 11844
Rtf1
Name: RTF1, Paf1/RNA polymerase II complex component
Synonyms: 2900005O08Rik, 6530416A09Rik, Gtl7
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 76246
Homologene: 133868
Hook1
Name: hook microtubule tethering protein 1
Synonyms: azh, abnormal spermatozoon head shape, A930033L17Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 77963
Homologene: 9289
Zfp961
Name: zinc finger protein 961
Synonyms: BC049349, A230105L22Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234413
Homologene: 136286
Cdan1
Name: codanin 1
Synonyms: CDA1, 1500015A01Rik, CDA-I, codanin-1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 68968
HGNC: HGNC:1713
Homologene: 16324
Celf2
Name: CUGBP, Elav-like family member 2
Synonyms: ETR-3, B230345P09Rik, Cugbp2, Napor-2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14007
HGNC: HGNC:2550
Homologene: 4783
Tcerg1
Name: transcription elongation regulator 1 (CA150)
Synonyms: 2410022J09Rik, p144, Taf2s, Fbp28, 2900090C16Rik, ca150
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 56070
Homologene: 4879
Rai1
Name: retinoic acid induced 1
Synonyms: Gt1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 19377
HGNC: HGNC:9834
Homologene: 7508
Washc5
Name: WASH complex subunit 5
Synonyms: strumpellin, E430025E21Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223593
VEGA: 15
Homologene: 8898
Trpc6
Name: transient receptor potential cation channel, subfamily C, member 6
Synonyms: Trrp6, mtrp6
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 22068
VEGA: 9
Homologene: 37944
Ttn
Name: titin
Synonyms: connectin, shru, D330041I19Rik, 2310057K23Rik, mdm, D830007G01Rik, 2310074I15Rik, 1100001C23Rik, 2310036G12Rik, L56
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Dhx36
Name: DEAH-box helicase 36
Synonyms: 2810407E23Rik, RHAU, Ddx36
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 72162
Homologene: 6356
Clcn3
Name: chloride channel, voltage-sensitive 3
Synonyms: Clc3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 12725
HGNC: HGNC:2021
Homologene: 20435
Dnah14
Name: dynein, axonemal, heavy chain 14
Synonyms: Gm980, Dnahc14, LOC381311, A230079K17Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 240960
HGNC: HGNC:2945
Homologene: 90078
Snapc4
Name: small nuclear RNA activating complex, polypeptide 4
Synonyms: 5730436L13Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227644
Homologene: 2321
Wdfy4
Name: WD repeat and FYVE domain containing 4
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 545030
Homologene: 83473
Gm5134
Name: predicted gene 5134
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 333669
Homologene: 129891
Ptchd4
Name: patched domain containing 4
Synonyms: 3110082D06Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 627626
VEGA: 17
Homologene: 78322
Slx4
Name: SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
Synonyms: D16Bwg1016e, Btbd12
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 52864
Homologene: 23770
Csmd3
Name: CUB and Sushi multiple domains 3
Synonyms: 4930500N14Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 239420
Homologene: 65982
Rint1
Name: RAD50 interactor 1
Synonyms: 1500019C06Rik, 2810450M21Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 72772
Homologene: 11070
Ugt2b37
Name: UDP glucuronosyltransferase 2 family, polypeptide B37
Synonyms: 0610033E06Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 112417
Homologene: 137225
Or14j3
Name: olfactory receptor family 14 subfamily J member 3
Synonyms: MOR218-10, GA_x6K02T2PSCP-2049802-2048870, Olfr114
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 258284
Homologene: 133642
Sh3bp4
Name: SH3-domain binding protein 4
Synonyms: BOG25
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 98402
Homologene: 8726
Phldb2
Name: pleckstrin homology like domain, family B, member 2
Synonyms: LL5b, C820004H04Rik, LL5beta
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 208177
Homologene: 17100
Cbfa2t3
Name: CBFA2/RUNX1 translocation partner 3
Synonyms: ETO-2, Eto2, A630044F12Rik, MTGR2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 12398
HGNC: HGNC:1537
Homologene: 74543
Zmat4
Name: zinc finger, matrin type 4
Synonyms: 9630048M01Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 320158
Homologene: 81899
Galc
Name: galactosylceramidase
Synonyms: 2310068B06Rik, galactocerebrosidase, A930008M05Rik, Gacy
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 14420
VEGA: 12
HGNC: HGNC:4115
Homologene: 124
Noxred1
Name: NADP+ dependent oxidoreductase domain containing 1
Synonyms: 4933437F05Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 71275
VEGA: 12
Homologene: 51388
Arhgef19
Name: Rho guanine nucleotide exchange factor 19
Synonyms: WGEF, 6430573B13Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 213649
Homologene: 17710
Vnn3
Name: vanin 3
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 26464
Homologene: 48295
Fcgrt
Name: Fc fragment of IgG receptor and transporter
Synonyms: FcRn, neonatal Fc receptor
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 14132
HGNC: HGNC:3621
Homologene: 3030
9430097D07Rik
Name: RIKEN cDNA 9430097D07 gene
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 319245
VEGA: 2
Rnf170
Name: ring finger protein 170
Synonyms: 6720407G21Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 77733
Homologene: 12807
Ssh3
Name: slingshot protein phosphatase 3
Synonyms: SSH-3
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 245857
VEGA: 19
Homologene: 32372
Or52r1c
Name: olfactory receptor family 52 subfamily R member 1C
Synonyms: GA_x6K02T2PBJ9-5796876-5797820, MOR30-2, Olfr584
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259056
Tmem220
Name: transmembrane protein 220
Synonyms: A730055C05Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 338369
Homologene: 18579
Mdfic
Name: MyoD family inhibitor domain containing
Synonyms: clone 1.5, Kdt1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16543
Homologene: 18404
Ldha
Name: lactate dehydrogenase A
Synonyms: LDH-A, l7R2, Ldh-1, lactate dehydrogenase-A, Ldh1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 16828
HGNC: HGNC:6535
Homologene: 56495
Parp16
Name: poly (ADP-ribose) polymerase family, member 16
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 214424
VEGA: 9
Homologene: 9878
Sectm1a
Name: secreted and transmembrane 1A
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 209588
Homologene: 134112
Haao
Name: 3-hydroxyanthranilate 3,4-dioxygenase
Synonyms: 3HAO, 3-HAO, 3-HAOxase, 0610012J07Rik, 0610007K21Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 107766
VEGA: 17
HGNC: HGNC:4796
Homologene: 8148
Cyp4v3
Name: cytochrome P450, family 4, subfamily v, polypeptide 3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 102294
Homologene: 133054
Tas2r121
Name: taste receptor, type 2, member 121
Synonyms: mGR21, mT2r48, Tas2r21, T2R21
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 387349
Homologene: 41542
Ftdc1
Name: ferritin domain containing 1
Synonyms: LOC385656, LOC328695, Gm813
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 328695
VEGA: 16
Pdzk1
Name: PDZ domain containing 1
Synonyms: 4921513F16Rik, Nherf3, mPDZK1, 1700023D20Rik, 2610507N21Rik, D3Ertd537e
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 59020
Homologene: 1964
Fkrp
Name: fukutin related protein
Synonyms: LGMD1I, MDC1C, A830029B19Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243853
Homologene: 11513
Krtap24-1
Name: keratin associated protein 24-1
Synonyms: Gm312, LOC239932
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 239932
VEGA: 16
Homologene: 88056
Trdv1
Name: T cell receptor delta variable 1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 627813
Ccl9
Name: C-C motif chemokine ligand 9
Synonyms: MRP-2, Scya9, Scya10, MIP-1 gamma, CCF18
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 20308
Homologene: 86734
Igdcc3
Name: immunoglobulin superfamily, DCC subclass, member 3
Synonyms: Punc, 2810401C09Rik, WI-14920
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 19289
VEGA: 9
HGNC: HGNC:9700
Homologene: 3590
Ighv10-3
Name: immunoglobulin heavy variable V10-3
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 380809
HGNC: HGNC:5623
Pusl1
Name: pseudouridylate synthase-like 1
Synonyms: 2810021I11Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 433813
Homologene: 13655
Evi2
Name: ecotropic viral integration site 2
Synonyms: Gm21975
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 101488212
HGNC: HGNC:3500
Homologene: 48438
Ighv1-62-1
Name: immunoglobulin heavy variable 1-62-1
Synonyms: Gm9232
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 668544
Prrt1b
Name: proline rich transmembrane protein 1B
Synonyms: Gm13420
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 433415
Homologene: 139519
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to A, chromosome 1 at 89,145,750 bp (GRCm38)
  • A to T, chromosome 1 at 181,622,979 bp (GRCm38)
  • A to T, chromosome 2 at 6,721,538 bp (GRCm38)
  • A to T, chromosome 2 at 26,378,521 bp (GRCm38)
  • A to T, chromosome 2 at 29,747,536 bp (GRCm38)
  • A to C, chromosome 2 at 32,575,235 bp (GRCm38)
  • A to T, chromosome 2 at 58,315,995 bp (GRCm38)
  • T to C, chromosome 2 at 76,794,683 bp (GRCm38)
  • A to T, chromosome 2 at 91,548,832 bp (GRCm38)
  • A to G, chromosome 2 at 119,705,505 bp (GRCm38)
  • G to T, chromosome 2 at 120,724,169 bp (GRCm38)
  • A to G, chromosome 3 at 62,472,045 bp (GRCm38)
  • A to G, chromosome 3 at 96,855,858 bp (GRCm38)
  • T to A, chromosome 4 at 96,016,441 bp (GRCm38)
  • T to C, chromosome 4 at 141,249,292 bp (GRCm38)
  • T to C, chromosome 4 at 155,891,637 bp (GRCm38)
  • T to A, chromosome 5 at 23,800,723 bp (GRCm38)
  • T to A, chromosome 5 at 87,242,943 bp (GRCm38)
  • A to G, chromosome 5 at 129,539,784 bp (GRCm38)
  • T to A, chromosome 6 at 15,770,515 bp (GRCm38)
  • T to G, chromosome 6 at 132,700,802 bp (GRCm38)
  • G to T, chromosome 7 at 16,811,187 bp (GRCm38)
  • G to A, chromosome 7 at 16,838,571 bp (GRCm38)
  • T to G, chromosome 7 at 45,095,429 bp (GRCm38)
  • A to T, chromosome 7 at 46,855,032 bp (GRCm38)
  • T to C, chromosome 7 at 103,085,989 bp (GRCm38)
  • G to A, chromosome 8 at 23,748,491 bp (GRCm38)
  • A to G, chromosome 8 at 26,129,215 bp (GRCm38)
  • A to T, chromosome 8 at 45,320,666 bp (GRCm38)
  • T to C, chromosome 8 at 60,937,400 bp (GRCm38)
  • T to A, chromosome 8 at 71,968,089 bp (GRCm38)
  • T to C, chromosome 8 at 90,986,173 bp (GRCm38)
  • T to A, chromosome 8 at 122,638,197 bp (GRCm38)
  • A to G, chromosome 9 at 8,634,189 bp (GRCm38)
  • A to G, chromosome 9 at 65,182,998 bp (GRCm38)
  • A to G, chromosome 9 at 65,233,727 bp (GRCm38)
  • G to A, chromosome 9 at 110,072,706 bp (GRCm38)
  • T to C, chromosome 10 at 11,213,504 bp (GRCm38)
  • C to T, chromosome 10 at 23,869,556 bp (GRCm38)
  • A to T, chromosome 10 at 75,992,497 bp (GRCm38)
  • G to A, chromosome 11 at 60,189,339 bp (GRCm38)
  • G to T, chromosome 11 at 67,025,260 bp (GRCm38)
  • C to T, chromosome 11 at 79,515,757 bp (GRCm38)
  • T to A, chromosome 11 at 83,575,412 bp (GRCm38)
  • G to T, chromosome 11 at 121,069,664 bp (GRCm38)
  • T to A, chromosome 12 at 87,224,918 bp (GRCm38)
  • G to A, chromosome 12 at 98,259,314 bp (GRCm38)
  • C to T, chromosome 12 at 114,523,634 bp (GRCm38)
  • G to T, chromosome 12 at 115,387,085 bp (GRCm38)
  • T to C, chromosome 13 at 49,589,860 bp (GRCm38)
  • T to C, chromosome 14 at 33,125,936 bp (GRCm38)
  • T to G, chromosome 14 at 47,673,051 bp (GRCm38)
  • G to A, chromosome 14 at 53,882,206 bp (GRCm38)
  • C to A, chromosome 15 at 47,696,687 bp (GRCm38)
  • T to A, chromosome 15 at 59,345,343 bp (GRCm38)
  • A to G, chromosome 15 at 81,687,922 bp (GRCm38)
  • G to T, chromosome 16 at 3,986,464 bp (GRCm38)
  • T to A, chromosome 16 at 45,781,393 bp (GRCm38)
  • T to A, chromosome 16 at 56,123,914 bp (GRCm38)
  • A to G, chromosome 16 at 58,614,611 bp (GRCm38)
  • T to C, chromosome 16 at 88,611,490 bp (GRCm38)
  • C to T, chromosome 17 at 37,590,023 bp (GRCm38)
  • C to T, chromosome 17 at 42,502,750 bp (GRCm38)
  • T to C, chromosome 17 at 83,834,786 bp (GRCm38)
  • C to T, chromosome 18 at 42,530,771 bp (GRCm38)
  • C to T, chromosome 19 at 4,262,409 bp (GRCm38)
  • A to C, chromosome 19 at 24,100,843 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9718 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069965-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.