Strain Name:
C57BL/6J-MtgxR9721Btlr/Mmmh
Stock Number:
069968-MU
Citation ID:
RRID:MMRRC_069968-MU
Other Names:
R9721 (G1)
Major Collection:

Strain Information

Cdh11
Name: cadherin 11
Synonyms: osteoblast-cadherin, OB-cadherin, Cad11
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 12552
HGNC: HGNC:1750
Homologene: 1361
Pzp
Name: PZP, alpha-2-macroglobulin like
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 11287
Homologene: 104112
Il4i1
Name: interleukin 4 induced 1
Synonyms: Fig1-ps, Fig1, H46, H4, H-46, H-4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 14204
Homologene: 22567
Dst
Name: dystonin
Synonyms: bullous pemphigoid antigen 1, BPAG1-n, BPAG1, Bpag1, Bpag, ah, Macf2, bullous pemphigoid antigen 1, athetoid, 2310001O04Rik, nmf203, A830042E19Rik, nmf339
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 13518
HGNC: HGNC:1090
Homologene: 136716
Ggta1
Name: glycoprotein galactosyltransferase alpha 1, 3
Synonyms: GALT, alpha Gal, Gal, glycoprotein alpha galactosyl transferase 1, alpha3GalT, Ggta-1, Ggta
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14594
HGNC: HGNC:4253
Homologene: 7730
Nup93
Name: nucleoporin 93
Synonyms: 2410008G02Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 71805
Homologene: 40971
Zc3h4
Name: zinc finger CCCH-type containing 4
Synonyms: LOC330474, Bwq1, Kiaa1064-hp
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 330474
Homologene: 87150
Kntc1
Name: kinetochore associated 1
Synonyms: jgl
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 208628
Homologene: 32227
Ddx19a
Name: DEAD box helicase 19a
Synonyms: Eif4a-rs1, DBP5, Ddx19, DEAD (Asp-Glu-Ala-Asp) box polypeptide 19a
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 13680
Homologene: 5240
Tut4
Name: terminal uridylyl transferase 4
Synonyms: 6030404K05Rik, 9230115F04Rik, Tent3a, Zcchc11
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230594
Homologene: 35279
Kif18a
Name: kinesin family member 18A
Synonyms: N-8 kinesin, B130001M12Rik, gcd2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228421
Homologene: 41820
Itpr1
Name: inositol 1,4,5-trisphosphate receptor 1
Synonyms: P400, IP3R1, Pcp-1, Itpr-1, Ip3r, opt, InsP3R type I, Pcp1, wblo
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16438
HGNC: HGNC:6180
Homologene: 1673
Ep300
Name: E1A binding protein p300
Synonyms: p300, KAT3B
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 328572
HGNC: HGNC:3373
Homologene: 1094
Atp13a1
Name: ATPase type 13A1
Synonyms: catp, Cgi152, Atp13a
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 170759
VEGA: 8
Homologene: 5791
Gls
Name: glutaminase
Synonyms: B230365M23Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 14660
HGNC: HGNC:4331
Homologene: 22726
Ecpas
Name: Ecm29 proteasome adaptor and scaffold
Synonyms: AI314180
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230249
Homologene: 6056
AU040320
Name: expressed sequence AU040320
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100317
Homologene: 11764
Bicra
Name: BRD4 interacting chromatin remodeling complex associated protein
Synonyms: Gltscr1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243842
HGNC: HGNC:4332
Homologene: 9250
Eif5b
Name: eukaryotic translation initiation factor 5B
Synonyms: IF2, A030003E17Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226982
Homologene: 134613
Mphosph9
Name: M-phase phosphoprotein 9
Synonyms: 4930548D04Rik, MPP-9, MPP9, B930097C17Rik, 9630025B04Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 269702
HGNC: HGNC:7215
Homologene: 11256
Dhx33
Name: DEAH-box helicase 33
Synonyms: 9430096J02Rik, 3110057P17Rik, Ddx33, DEAH (Asp-Glu-Ala-His) box polypeptide 33
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216877
Homologene: 56235
Mgat5b
Name: mannoside acetylglucosaminyltransferase 5, isoenzyme B
Synonyms: GnT-IX
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 268510
Homologene: 27821
Rerg
Name: RAS-like, estrogen-regulated, growth-inhibitor
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232441
Homologene: 50026
Tsc2
Name: TSC complex subunit 2
Synonyms: tuberin, Nafld, tuberous sclerosis 2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 22084
VEGA: 17
Homologene: 462
Ltbr
Name: lymphotoxin B receptor
Synonyms: TNFRrp, TNF receptor-related protein, LT-beta receptor, LT beta-R, Tnfbr, Ltar, TNF-R-III, TNFCR, TNFR2-RP, LTbetaR, Tnfrsf3
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 17000
HGNC: HGNC:6718
Homologene: 1753
Tek
Name: TEK receptor tyrosine kinase
Synonyms: Hyk, Tie2, Cd202b, tie-2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 21687
Homologene: 397
Lama2
Name: laminin, alpha 2
Synonyms: merosin, mer
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 16773
HGNC: HGNC:6482
Homologene: 37306
AAdacl4fm3
Name: AADACL4 family member 3
Synonyms: Gm13178
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 546849
Homologene: 82586
Unc13b
Name: unc-13 homolog B
Synonyms: Unc13h2, Munc13-2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 22249
Homologene: 31376
Pcdhb4
Name: protocadherin beta 4
Synonyms: Pcdhb5A, PcdhbD
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93875
HGNC: HGNC:8690
Homologene: 62176
Psd
Name: pleckstrin and Sec7 domain containing
Synonyms: Efa6, 1110007H17Rik, Psdl, Efa6a
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 73728
VEGA: 19
HGNC: HGNC:9507
Homologene: 31115
Trpm3
Name: transient receptor potential cation channel, subfamily M, member 3
Synonyms: B930001P07Rik, 6330504P12Rik, MLSN2, melastatin 2, LTRPC3
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226025
VEGA: 19
Homologene: 62287
Trpm6
Name: transient receptor potential cation channel, subfamily M, member 6
Synonyms: CHAK2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 225997
VEGA: 19
Homologene: 9767
Cplane1
Name: ciliogenesis and planar polarity effector 1
Synonyms: b2b012Clo, Jbts17, Hug, 2410089E03Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 73692
Homologene: 11315
Xylt1
Name: xylosyltransferase 1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233781
Homologene: 32534
Fgd5
Name: FYVE, RhoGEF and PH domain containing 5
Synonyms: ZFYVE23, C330025N11Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232237
Homologene: 27798
Nckap5
Name: NCK-associated protein 5
Synonyms: LOC380609, D130011D22Rik, E030049G20Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 210356
Homologene: 35542
Zfp14
Name: zinc finger protein 14
Synonyms: Krox-9, Zfp-14, 4732429I09Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243906
Homologene: 45619
Kif21a
Name: kinesin family member 21A
Synonyms: N-5 kinesin
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 16564
VEGA: 15
Homologene: 56761
Or10j7
Name: olfactory receptor family 10 subfamily J member 7
Synonyms: GA_x6K02T2R7CC-664297-665229, MOR267-5, Olfr1406
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 258758
Homologene: 133644
Spn
Name: sialophorin
Synonyms: leukosialin, 3E8 antigen, Cd43, Ly-48, A630014B01Rik, Galgp, Ly48
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 20737
Homologene: 36108
Cfap65
Name: cilia and flagella associated protein 65
Synonyms: B230363K08Rik, Ccdc108
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 241116
Homologene: 28093
Ngef
Name: neuronal guanine nucleotide exchange factor
Synonyms: ephexin, Tims2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 53972
HGNC: HGNC:7807
Homologene: 75120
1700006A11Rik
Name: RIKEN cDNA 1700006A11 gene
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 71824
Lrrk1
Name: leucine-rich repeat kinase 1
Synonyms: D130026O16Rik, C230002E15Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233328
Homologene: 23464
Fam83a
Name: family with sequence similarity 83, member A
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 239463
Homologene: 13158
Samd9l
Name: sterile alpha motif domain containing 9-like
Synonyms: ESTM25
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 209086
HGNC: HGNC:1349
Homologene: 7707
Vmn1r52
Name: vomeronasal 1 receptor 52
Synonyms: VN3, V1ra7
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 113849
Klf11
Name: Kruppel-like transcription factor 11
Synonyms: Tieg2b, D12Ertd427e, Tieg2, Tieg3
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 194655
Homologene: 2668
Pfpl
Name: pore forming protein-like
Synonyms: Epcs5, Epcs50
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 56093
VEGA: 19
Homologene: 130704
Matcap1
Name: microtubule associated tyrosine carboxypeptidase 1
Synonyms: MATCAP, 4931428F04Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 74356
Homologene: 47588
Flt4
Name: FMS-like tyrosine kinase 4
Synonyms: VEGFR3, VEGFR-3, Flt-4
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 14257
HGNC: HGNC:3767
Homologene: 7321
Spata31e3
Name: spermatogenesis associated 31 subfamily E member 3
Synonyms: LOC380882, Gm906
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 380882
VEGA: 13
Homologene: 134512
Alox8
Name: arachidonate 8-lipoxygenase
Synonyms: 8S-lipoxygenase, 8-LOX, 8S-LOX, Alox15b
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 11688
HGNC: HGNC:434
Homologene: 886
Or5b3
Name: olfactory receptor family 5 subfamily B member 3
Synonyms: GA_x6K02T2RE5P-3743369-3744289, MOR202-11, Olfr1469
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258690
HGNC: HGNC:8324
Homologene: 133675
Ifi214
Name: interferon activated gene 214
Synonyms: BC094916, Pyhin-B
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 545384
HGNC: HGNC:5395
Homologene: 115929
Dhrs7c
Name: dehydrogenase/reductase 7C
Synonyms: 1110001P11Rik, dehydrogenase/reductase (SDR family) member 7C
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 68460
Homologene: 19108
Smok2b
Name: sperm motility kinase 2B
Synonyms: LOC236574
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 236574
Homologene: 128738
Phactr3
Name: phosphatase and actin regulator 3
Synonyms: scapinin, 1500003N10Rik, 4930415A02Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 74189
Homologene: 14482
Gm5414
Name: predicted gene 5414
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 406223
VEGA: 15
Or4c110
Name: olfactory receptor family 4 subfamily C member 110
Synonyms: GA_x6K02T2Q125-50482823-50481885, MOR233-13, Olfr1215
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258451
Homologene: 74071
Malrd1
Name: MAM and LDL receptor class A domain containing 1
Synonyms: Gm13318, Gm13364, Diet1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 102635496
Homologene: 136214
Gm9887
Name: predicted gene 9887
Type: Gene
Species: Mouse
Chromosome: 12
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to G, chromosome 1 at 34,192,785 bp (GRCm38)
  • T to C, chromosome 1 at 38,037,659 bp (GRCm38)
  • A to G, chromosome 1 at 52,212,268 bp (GRCm38)
  • T to C, chromosome 1 at 74,919,342 bp (GRCm38)
  • T to A, chromosome 1 at 87,479,135 bp (GRCm38)
  • C to T, chromosome 1 at 126,027,280 bp (GRCm38)
  • C to A, chromosome 1 at 173,184,348 bp (GRCm38)
  • T to C, chromosome 1 at 173,527,913 bp (GRCm38)
  • C to T, chromosome 2 at 15,696,827 bp (GRCm38)
  • G to T, chromosome 2 at 35,413,406 bp (GRCm38)
  • T to C, chromosome 2 at 89,001,716 bp (GRCm38)
  • T to C, chromosome 2 at 109,293,055 bp (GRCm38)
  • G to A, chromosome 2 at 178,256,250 bp (GRCm38)
  • A to T, chromosome 3 at 124,419,283 bp (GRCm38)
  • A to G, chromosome 4 at 43,101,869 bp (GRCm38)
  • A to T, chromosome 4 at 58,850,938 bp (GRCm38)
  • T to G, chromosome 4 at 94,804,302 bp (GRCm38)
  • T to A, chromosome 4 at 108,555,581 bp (GRCm38)
  • G to A, chromosome 4 at 126,839,648 bp (GRCm38)
  • A to T, chromosome 4 at 144,703,372 bp (GRCm38)
  • A to G, chromosome 5 at 123,801,885 bp (GRCm38)
  • A to T, chromosome 5 at 124,298,675 bp (GRCm38)
  • T to C, chromosome 6 at 3,375,854 bp (GRCm38)
  • G to A, chromosome 6 at 90,179,026 bp (GRCm38)
  • A to T, chromosome 6 at 91,988,297 bp (GRCm38)
  • A to T, chromosome 6 at 108,406,102 bp (GRCm38)
  • G to A, chromosome 6 at 125,307,385 bp (GRCm38)
  • A to G, chromosome 6 at 128,495,191 bp (GRCm38)
  • T to A, chromosome 6 at 137,056,417 bp (GRCm38)
  • A to G, chromosome 7 at 15,979,176 bp (GRCm38)
  • C to A, chromosome 7 at 16,434,845 bp (GRCm38)
  • A to T, chromosome 7 at 30,039,184 bp (GRCm38)
  • A to G, chromosome 7 at 44,839,689 bp (GRCm38)
  • T to C, chromosome 7 at 66,274,875 bp (GRCm38)
  • A to T, chromosome 7 at 117,549,020 bp (GRCm38)
  • A to G, chromosome 7 at 127,136,265 bp (GRCm38)
  • A to G, chromosome 8 at 69,799,437 bp (GRCm38)
  • T to C, chromosome 8 at 94,303,685 bp (GRCm38)
  • A to T, chromosome 8 at 102,679,625 bp (GRCm38)
  • A to T, chromosome 8 at 105,283,188 bp (GRCm38)
  • A to G, chromosome 8 at 110,978,475 bp (GRCm38)
  • T to C, chromosome 10 at 27,467,342 bp (GRCm38)
  • G to A, chromosome 11 at 49,644,433 bp (GRCm38)
  • T to A, chromosome 11 at 67,815,078 bp (GRCm38)
  • T to A, chromosome 11 at 69,197,085 bp (GRCm38)
  • A to G, chromosome 11 at 71,001,598 bp (GRCm38)
  • T to C, chromosome 11 at 116,966,769 bp (GRCm38)
  • T to A, chromosome 12 at 24,660,241 bp (GRCm38)
  • C to G, chromosome 12 at 69,371,855 bp (GRCm38)
  • T to C, chromosome 13 at 50,246,652 bp (GRCm38)
  • A to G, chromosome 15 at 8,225,409 bp (GRCm38)
  • A to G, chromosome 15 at 57,986,117 bp (GRCm38)
  • A to G, chromosome 15 at 81,608,315 bp (GRCm38)
  • A to T, chromosome 15 at 90,971,127 bp (GRCm38)
  • A to T, chromosome 15 at 101,628,147 bp (GRCm38)
  • C to A, chromosome 17 at 13,234,978 bp (GRCm38)
  • G to A, chromosome 17 at 24,599,642 bp (GRCm38)
  • C to A, chromosome 18 at 37,309,852 bp (GRCm38)
  • G to C, chromosome 19 at 12,428,933 bp (GRCm38)
  • A to T, chromosome 19 at 13,410,970 bp (GRCm38)
  • A to G, chromosome 19 at 18,829,972 bp (GRCm38)
  • A to T, chromosome 19 at 22,889,398 bp (GRCm38)
  • C to T, chromosome 19 at 46,323,189 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9721 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069968-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.