Strain Name:
Tan Streak
Stock Number:
037610-MU
Citation ID:
RRID:MMRRC_037610-MU
Other Names:
TNS
Major Collection:

Gene Information

Genetic Alterations
Spontaneous mutation
Genotype Determination
ES Cell Line
N/A
Phenotype
The tan streak trait is evident within a few days of birth, since the affected deer mice are markedly paler in color than their wild-type counterparts. The phenotype is fully expressed by weaning. Superficially, the coat is white with a pale tan streak extending along the mid-dorsal line from a broader tan patch in the shoulder region. The patch with the dorsal streak forms a cross pattern in some animals. The dorsal stripe may be much abbreviated in some specimens and evident only in the cervical area, while in others it may extend to the base of the tail. Typically the streak extends about one-half to two-thirds the length of the body. Microscopic examination of hairs from the pigmented mid-dorsal stripe shows that the stripe contains mostly hairs with sparse tan-yellow pigment granules along the length, but the pigment is somewhat more concentrated in the distal 40%. There is no distinct agouti band. However, constrictions in the individual hairs are present. The pigment has more an aspect of brown eumelanin than of phaeomelanin. Some hairs have occasional large pigment clumps. A minority of hairs in the stripe are devoid of pigment. A given hair tends to contain color granules along most of its length, or else not at all. In the lateral white portion of the coat pigment is completely absent. The eyes are fully pigmented. The ears and tail stripe are pigmented, but are much paler and more tan than in the wild-type. The scrotum is lightly pigmented, as well.
Strain Development
Source: In 1986 a group of P.m. nubiterrae (Cloudland deer mouse) were captured in the southern Blue Ridge Mountains of Macon County NC, to establish a small breeding colony at Clemson University. All of the founder animals were wild-type. The following year the first tan streak deer mouse, a male, appeared from a mating between wild-caught animals.
Primary Reference

Wang, LRK., J. P. Crossland JP, and Dawson WD. Coat color genetics of Peromyscus: II. Tan streak-a new recessive mutation in the deermouse, P. maniculatus. J Hered. 1993 Jul-Aug;84(4):304-6. (Medline PMID: 8340619)

For more information, please see Tan Streak on the Peromyscus Genetic Stock Center website.

Colony and Husbandry Informationon

Colony Surveillance Program and Current Health Reports

Mice derived from requested cell lines via Microinjection services will be pathogen tested prior to delivery of mice and health reports will be provided. If you require additional health status information prior to requesting microinjection please email mmrrc@missouri.edu.
Coat Color
Homozygous (tns/tns) coat color is white with a pale tan streak extending along the mid-dorsal line from a broader tan patch in the shoulder region

Heterozygous (tns/+) are the same a wild-type.

Other

MMRRC Breeding System
Not applicable; only cryopreserved sperm is available. The parent colony was sufficiently large to use a random breeding scheme
Breeding Scheme(s)
Not applicable; only cryopreserved sperm is available; mice cryorecovered (see below) can be bred Wild-type female x Wild-type male
Overall Breeding Performance
Peromyscus mice breed best in a 16:8 light / dark cycle.
Average litter size
3
Recommended wean age
25 days

Order Request Information

Male mice were obtained from the Peromyscus Genetic Stock Center as part of a long term project to develop cropreservation techniques for Peromyscus. Sperm have been cryopreserved and are available. However, cryorecovery techniques have yet to be developed.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

- Products for this strain are Not Yet Available for Ordering
- If you register interest in this strain, you will be notified when it becomes available for ordering.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.