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Gene Information

Genetic Alterations
Spontaneous mutation
Genotype Determination
These deer mice exhibit a pronounced tremor and staggering, awkward gait. The tremor is expressed whenever the animal is awake and at rest. The awkward gait is due to uncoordinated movements of the hind limbs. The trait is most strongly expressed in adults, but there is variable expressivities and low grade 'boggling' behavior is not easily distinguished from the wild-type. The tremor involves the whole body, but head movements are more noticeable. Boggler deer mice are less adept at climbing than normal arivals, but swimming ability is unimpaired. The trait cannot be recognized until after three months of age, and expression occasionally is delayed until the animal is more than a year old.
MeSH Terms
  • Age Factors
  • Animals
  • Ataxia/genetics
  • Ataxia/pathology
  • Axons
  • Behavior, Animal
  • Central Nervous System/pathology
  • Cerebellum/pathology
  • Demyelinating Diseases/pathology
  • Hindlimb
  • Mutation
  • Orientation
  • Rodent Diseases/genetics
  • Rodent Diseases/pathology
  • Sex Factors
  • Species Specificity
  • Tremor/genetics
  • Tremor/pathology
Strain Development
Source: About 1948. University of Michigan. The trait appeared within a stock of P.m. blandus descended from deer mice trapped near Tularosa, New Mexico. Apparently the first laboratory generation carried the mutant gene.
Primary Reference

Vandermeer J, Barto E. Axonal dystrophy in a deer mouse (Peromyscus maniculatus) with an inherited ataxia and tremor. J Neuropathol Exp Neurol. 1969 Apr;28(2):257-66. (Medline PMID: 5787431).

For more information, please see Boggler on the Peromyscus Genetic Stock Center website.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

For more information about this colony's health status contact
MMRRC Breeding System
Not applicable; only cryopreserved sperm is available. The parent colony was sufficiently large to use a random breeding scheme
Breeding Scheme(s)
Not applicable; only cryopreserved sperm is available; mice cryorecovered (see below) can be bred Wild-type female x Wild-type male
Overall Breeding Performance
Peromyscus mice breed best in a 16:8 light / dark cycle.
Viability and Fertility: Female Male Comments
Homozygotes are viable: Yes Yes
Homozygotes are fertile: Yes Yes
Heterozygotes are fertile: Yes Yes
Age Reproductive Decline: Unknown Unknown
Average litter size
Recommended wean age
25 days

Order Request Information

Male mice were obtained from the Peromyscus Genetic Stock Center as part of a long term project to develop cropreservation techniques for Peromyscus. Sperm have been cryopreserved and are available. However, cryorecovery techniques have yet to be developed.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

- Products for this strain are Not Yet Available for Ordering
- If you register interest in this strain, you will be notified when it becomes available for ordering.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.