Strain Name:
C57BL/6J-MtgxR0045Btlr/Mmmh
Stock Number:
038339-MU
Citation ID:
RRID:MMRRC_038339-MU
Other Names:
R0045 (G1), C57BL/6J-MtgxR0045Btlr
Major Collection:

Gene Information

Cds2
Name: CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
Synonyms: 5730460C18Rik, 5730450N06Rik, D2Wsu127e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 110911
HGNC: HGNC:1801
Homologene: 37854
Cdon
Name: cell adhesion molecule-related/down-regulated by oncogenes
Synonyms: CDO, CAM-related/down-regulated by oncogenes
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 57810
Homologene: 22996
Nnat
Name: neuronatin
Synonyms: Peg5, 5730414I02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18111
HGNC: HGNC:7860
Homologene: 36176
Gpr37l1
Name: G protein-coupled receptor 37-like 1
Synonyms: CAG-18, D0Kist8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 171469
Homologene: 3500
Tal1
Name: T cell acute lymphocytic leukemia 1
Synonyms: SCL/tal-1, Hpt, Scl, bHLHa17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 21349
Homologene: 2400
Atf2
Name: activating transcription factor 2
Synonyms: Creb2, D130078H02Rik, mXBP, ATF-2, CRE-BP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 11909
HGNC: HGNC:784
Homologene: 31061
Ppp2r3c
Name: protein phosphatase 2, regulatory subunit B'', gamma
Synonyms: G5pr, 4930511A21Rik, G4-1, 5730412A08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 59032
VEGA: 12
Homologene: 9915
Trp53bp1
Name: transformation related protein 53 binding protein 1
Synonyms: 53BP1, p53BP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 27223
Homologene: 4137
Slc25a13
Name: solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13
Synonyms: citrin, Ctrn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 50799
Homologene: 22800
Mtor
Name: mechanistic target of rapamycin kinase
Synonyms: flat, Frap1, FKBP-rapamycin-associated protein FRAP, mechanistic target of rapamycin (serine/threonine kinase), RAPT1, RAFT1, 2610315D21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 56717
HGNC: HGNC:3942
Homologene: 3637
Commd10
Name: COMM domain containing 10
Synonyms: 2310003A05Rik, DRWMS2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 69456
VEGA: 18
Homologene: 9404
Ascc3
Name: activating signal cointegrator 1 complex subunit 3
Synonyms: ASC1p200, Helic1, B630009I04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 77987
VEGA: 10
Homologene: 4973
Atf7ip
Name: activating transcription factor 7 interacting protein
Synonyms: ATFa-associated Modulator, Mcaf1, 2610204M12Rik, AM
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 54343
Homologene: 10051
Cog6
Name: component of oligomeric golgi complex 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 67542
Homologene: 10802
Wapl
Name: WAPL cohesin release factor
Synonyms: Wapal, A530089A20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 218914
Homologene: 41002
Vars
Name: valyl-tRNA synthetase
Synonyms: Bat6, Bat-6, D17H6S56E, G7a, Vars2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 22321
Homologene: 4587
Ripor2
Name: RHO family interacting cell polarization regulator 2
Synonyms: 1700108N18Rik, 6330500D04Rik, Fam65b, E430013J17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 193385
Homologene: 9284
Trpv4
Name: transient receptor potential cation channel, subfamily V, member 4
Synonyms: VRL-2, 0610033B08Rik, Trp12, OTRPC4, VROAC, VR-OAC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 63873
Homologene: 11003
Dram2
Name: DNA-damage regulated autophagy modulator 2
Synonyms: Tmem77, 2610318G18Rik, 2010305N14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 67171
Homologene: 23565
Il17b
Name: interleukin 17B
Synonyms: 1110006O16Rik, Zcyto7, 1700006N07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 56069
VEGA: 18
HGNC: HGNC:5982
Homologene: 8689
Usp8
Name: ubiquitin specific peptidase 8
Synonyms: Ubpy
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 84092
Homologene: 3782
Vac14
Name: Vac14 homolog (S. cerevisiae)
Synonyms: Tax1bp2, D8Wsu151e, ingls, Trx
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234729
Homologene: 6528
Vps13a
Name: vacuolar protein sorting 13A
Synonyms: 4930543C13Rik, 4930516E05Rik, D330038K10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 271564
VEGA: 19
HGNC: HGNC:1908
Homologene: 22068
Mavs
Name: mitochondrial antiviral signaling protein
Synonyms: IPS-1, D430028G21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228607
Homologene: 17004
Ttll5
Name: tubulin tyrosine ligase-like family, member 5
Synonyms: 1700048H13Rik, D630041K24Rik, STAMP, 4930556H18Rik, 2310009M18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 320244
Homologene: 9013
Atp12a
Name: ATPase, H+/K+ transporting, nongastric, alpha polypeptide
Synonyms: cHKA, Atp1al1, ATPase H+K+-transporting, alpha 2, HKalpha2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 192113
VEGA: 14
Homologene: 68197
Cdh23
Name: cadherin 23 (otocadherin)
Synonyms: mdfw, USH1D, ahl, nmf252, nmf181, nmf112, sals, bob, 4930542A03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 22295
Homologene: 11142
Arhgap30
Name: Rho GTPase activating protein 30
Synonyms: 6030405P05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226652
Homologene: 18766
Pclo
Name: piccolo (presynaptic cytomatrix protein)
Synonyms: Pico, Acz
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 26875
Homologene: 69111
Rapgef4
Name: Rap guanine nucleotide exchange factor (GEF) 4
Synonyms: 5730402K07Rik, cAMP-GEFII, 1300003D15Rik, 6330581N18Rik, Epac2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 56508
Homologene: 4451
Itga4
Name: integrin alpha 4
Synonyms: VLA-4 receptor, alpha 4 subunit
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 16401
HGNC: HGNC:6140
Homologene: 37364
Agbl1
Name: ATP/GTP binding protein-like 1
Synonyms: Nna1-l1, Ccp4, EG244071
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 244071
Homologene: 17552
Tecta
Name: tectorin alpha
Synonyms: Tctna, [a]-tectorin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 21683
Homologene: 3955
Liph
Name: lipase, member H
Synonyms: C130037N08Rik, D16Wsu119e, Lpdlr, PLA1B, mPA-PLA1, LPDLR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 239759
VEGA: 16
Homologene: 71802
Lcn5
Name: lipocalin 5
Synonyms: Erabp, mE-RABP, MEP10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 13863
Homologene: 7305
Myl3
Name: myosin, light polypeptide 3
Synonyms: ventricular, MLC1v, Mylc, MLC1s, alkali, slow skeletal
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 17897
HGNC: HGNC:7584
Homologene: 20099
Gsap
Name: gamma-secretase activating protein
Synonyms: Pion, A530088I07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 212167
Homologene: 45504
Gm8251
Name: predicted gene 8251
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 102636082
VEGA: 1
Homologene: 141149
Fsip1
Name: fibrous sheath-interacting protein 1
Synonyms: 1700012M13Rik, 4933432K11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 71313
Homologene: 12390
Stk35
Name: serine/threonine kinase 35
Synonyms: CLP-36 interacting kinase, CLIK1, 1700054C12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 67333
Homologene: 15441
Hsd3b5
Name: hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5
Synonyms: 3(beta)HSDV
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 15496
Homologene: 104115
Pakap
Name: paralemmin A kinase anchor protein
Synonyms: AKAP-KL, AF064781, Palm2Akap2, pEN70, 53-H12, Palm2, B230340M18Rik, Gm20459, Akap2, Palm2-Akap2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 11641
Wdr31
Name: WD repeat domain 31
Synonyms: 5430402I10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 71354
Homologene: 11360
C8a
Name: complement component 8, alpha polypeptide
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230558
HGNC: HGNC:1352
Homologene: 472
Kcnq4
Name: potassium voltage-gated channel, subfamily Q, member 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 60613
HGNC: HGNC:6298
Homologene: 78107
Lrrd1
Name: leucine rich repeats and death domain containing 1
Synonyms: 4932412H11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 242838
Homologene: 18247
Atg9b
Name: autophagy related 9B
Synonyms: eONE, Nos3as, Apg9l2, LOC213948
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 213948
Homologene: 72638
Gm10047
Name: predicted gene 10047
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Abcb9
Name: ATP-binding cassette, sub-family B (MDR/TAP), member 9
Synonyms: TAPL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 56325
HGNC: HGNC:50
Homologene: 10491
Lpcat3
Name: lysophosphatidylcholine acyltransferase 3
Synonyms: Mboat5, Oact5, Grcc3f
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 14792
Homologene: 14678
Klhl42
Name: kelch-like 42
Synonyms: C230080I20Rik, Klhdc5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232539
Homologene: 45842
Pcsk6
Name: proprotein convertase subtilisin/kexin type 6
Synonyms: PACE4, b2b2830Clo, SPC4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18553
HGNC: HGNC:8569
Homologene: 20569
Ap3b2
Name: adaptor-related protein complex 3, beta 2 subunit
Synonyms: Naptb, beta3B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 11775
HGNC: HGNC:567
Homologene: 55837
Vmn2r70
Name: vomeronasal 2, receptor 70
Synonyms: EG620835
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 670940
Homologene: 115466
Olfr293
Name: olfactory receptor 293
Synonyms: GA_x6K02T2NHDJ-9457744-9456734, MOR221-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 257906
Homologene: 79385
Olfr703
Name: olfactory receptor 703
Synonyms: GA_x6K02T2PBJ9-9222217-9223176, MOR283-7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258589
Htra1
Name: HtrA serine peptidase 1
Synonyms: HtrA1, L56, Prss11, insulin-like growth factor binding protein 5 protease, RSPP11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 56213
HGNC: HGNC:9476
Homologene: 31114
Muc5b
Name: mucin 5, subtype B, tracheobronchial
Synonyms: MUC9, MUC5, 2300002I04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 74180
HGNC: HGNC:7516
Homologene: 136756
Exoc3l
Name: exocyst complex component 3-like
Synonyms: C730015A04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 277978
Homologene: 18629
Olfr869
Name: olfactory receptor 869
Synonyms: GA_x6K02T2PVTD-13878275-13879204, MOR145-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258550
Homologene: 138312
Egr2
Name: early growth response 2
Synonyms: Egr-2, Krox20, NGF1-B, Krox-20, Zfp-25
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 13654
HGNC: HGNC:3239
Homologene: 20123
Abi3
Name: ABI gene family, member 3
Synonyms: 2210414K06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 66610
Homologene: 9505
Gm10840
Name: predicted gene 10840
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
VEGA: 11
Ltbp2
Name: latent transforming growth factor beta binding protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 16997
HGNC: HGNC:6715
Homologene: 369
Rpgrip1
Name: retinitis pigmentosa GTPase regulator interacting protein 1
Synonyms: nmf247, 4930505G06Rik, 4930401L23Rik, A930002K18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 77945
Homologene: 10679
Vpreb2
Name: pre-B lymphocyte gene 2
Synonyms: Vpreb-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 22363
VEGA: 16
Homologene: 84741
Arvcf
Name: armadillo repeat gene deleted in velocardiofacial syndrome
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 11877
HGNC: HGNC:728
Homologene: 31046
Olfr183
Name: olfactory receptor 183
Synonyms: GA_x54KRFPKG5P-55229158-55230087, MOR183-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 258478
Homologene: 27178
Jmjd8
Name: jumonji domain containing 8
Synonyms: 2610003J06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 72106
Homologene: 12441
D17H6S56E-5
Name: DNA segment, Chr 17, human D6S56E 5
Synonyms: G7e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 110956
VEGA: 17
Sh3pxd2a
Name: SH3 and PX domains 2A
Synonyms: Tks5, Fish, 2310014D11Rik, Sh3md1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 14218
VEGA: 19
Homologene: 7317
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 44,057,205 bp
  • A to G, chromosome 1 at 135,161,145 bp
  • A to G, chromosome 1 at 171,408,430 bp
  • T to C, chromosome 2 at 25,660,698 bp
  • A to G, chromosome 2 at 72,198,778 bp
  • G to T, chromosome 2 at 73,829,856 bp
  • A to T, chromosome 2 at 79,301,031 bp
  • C to A, chromosome 2 at 118,248,292 bp
  • A to C, chromosome 2 at 121,204,497 bp
  • A to G, chromosome 2 at 126,742,223 bp
  • A to T, chromosome 2 at 129,800,568 bp
  • G to A, chromosome 2 at 131,238,831 bp
  • G to T, chromosome 2 at 132,305,155 bp
  • A to T, chromosome 2 at 157,560,488 bp
  • T to C, chromosome 3 at 52,992,750 bp
  • T to A, chromosome 3 at 98,619,144 bp
  • T to C, chromosome 3 at 106,570,817 bp
  • T to C, chromosome 4 at 57,710,145 bp
  • G to T, chromosome 4 at 62,464,033 bp
  • T to C, chromosome 4 at 104,826,815 bp
  • A to G, chromosome 4 at 115,068,565 bp
  • T to A, chromosome 4 at 120,697,955 bp
  • C to G, chromosome 4 at 148,464,949 bp
  • A to G, chromosome 5 at 3,866,418 bp
  • C to T, chromosome 5 at 14,539,471 bp
  • T to C, chromosome 5 at 21,226,832 bp
  • G to T, chromosome 5 at 24,387,398 bp
  • T to A, chromosome 5 at 104,455,805 bp
  • A to G, chromosome 5 at 114,636,457 bp
  • T to C, chromosome 5 at 124,082,085 bp
  • A to T, chromosome 6 at 6,109,277 bp
  • T to C, chromosome 6 at 124,701,474 bp
  • A to G, chromosome 6 at 136,559,816 bp
  • A to G, chromosome 6 at 147,092,168 bp
  • T to A, chromosome 7 at 65,962,928 bp
  • T to C, chromosome 7 at 76,698,840 bp
  • T to C, chromosome 7 at 81,466,193 bp
  • T to C, chromosome 7 at 85,566,044 bp
  • T to C, chromosome 7 at 86,664,340 bp
  • T to A, chromosome 7 at 106,845,389 bp
  • T to A, chromosome 7 at 130,961,532 bp
  • T to A, chromosome 7 at 141,856,818 bp
  • C to T, chromosome 8 at 105,293,685 bp
  • G to A, chromosome 8 at 110,636,952 bp
  • A to T, chromosome 9 at 20,137,191 bp
  • G to A, chromosome 9 at 35,486,807 bp
  • G to A, chromosome 9 at 42,375,191 bp
  • A to C, chromosome 9 at 110,767,929 bp
  • C to T, chromosome 10 at 50,718,402 bp
  • T to C, chromosome 10 at 60,530,978 bp
  • T to A, chromosome 10 at 67,540,480 bp
  • A to G, chromosome 11 at 95,832,715 bp
  • C to A, chromosome 11 at 106,161,100 bp
  • T to A, chromosome 12 at 55,293,821 bp
  • G to A, chromosome 12 at 84,809,587 bp
  • T to C, chromosome 12 at 84,813,288 bp
  • T to G, chromosome 12 at 85,879,359 bp
  • A to G, chromosome 13 at 24,694,226 bp
  • A to G, chromosome 14 at 34,733,794 bp
  • A to T, chromosome 14 at 52,141,144 bp
  • G to A, chromosome 14 at 56,372,873 bp
  • T to C, chromosome 16 at 17,980,767 bp
  • T to A, chromosome 16 at 18,403,458 bp
  • T to C, chromosome 16 at 21,968,053 bp
  • G to A, chromosome 16 at 59,000,491 bp
  • A to G, chromosome 17 at 25,829,281 bp
  • C to A, chromosome 17 at 34,998,066 bp
  • A to T, chromosome 17 at 35,010,619 bp
  • T to C, chromosome 18 at 46,967,836 bp
  • G to A, chromosome 18 at 61,690,244 bp
  • A to T, chromosome 19 at 16,640,810 bp
  • A to G, chromosome 19 at 47,267,183 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0045 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038339-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.