Strain Name:
C57BL/6J-MtgxR0051Btlr/Mmmh
Stock Number:
038345-MU
Citation ID:
RRID:MMRRC_038345-MU
Other Names:
R0051 (G1), C57BL/6J-MtgxR0051Btlr
Major Collection:

Gene Information

Scarb1
Name: scavenger receptor class B, member 1
Synonyms: D5Ertd460e, Srb1, Cd36l1, Cla-1, SRBI, SR-BI, Hlb398, Hdlq1, Chohd1, Chohd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 20778
HGNC: HGNC:1664
Homologene: 21132
Slc12a5
Name: solute carrier family 12, member 5
Synonyms: KCC2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 57138
Homologene: 10665
Frrs1
Name: ferric-chelate reductase 1
Synonyms: Sdfr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 20321
Homologene: 40653
Anks3
Name: ankyrin repeat and sterile alpha motif domain containing 3
Synonyms: 2700067D09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 72615
VEGA: 16
Homologene: 12475
Rtel1
Name: regulator of telomere elongation helicase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 269400
Homologene: 13168
Drd5
Name: dopamine receptor D5
Synonyms: DRD1b, Drd-5, Gpcr1, Drd1b, D5R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 13492
HGNC: HGNC:3026
Homologene: 20216
Med13l
Name: mediator complex subunit 13-like
Synonyms: 2210413I17Rik, 6330591G05Rik, Trap240L, 9030618F05Rik, Thrap2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 76199
Homologene: 25256
Ncaph2
Name: non-SMC condensin II complex, subunit H2
Synonyms: 0610010J20Rik, 2610524G04Rik, D15Ertd785e, Kleisin beta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 52683
Homologene: 12045
Yeats2
Name: YEATS domain containing 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 208146
VEGA: 16
Homologene: 9967
Diaph3
Name: diaphanous related formin 3
Synonyms: p134MDia2, mDia2, 4930417P13Rik, Drf3, Diap3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 56419
VEGA: 14
Homologene: 84829
Ankrd11
Name: ankyrin repeat domain 11
Synonyms: 2410104C19Rik, 9530048I21Rik, 3010027A04Rik, Yod
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 77087
Homologene: 69134
Tut4
Name: terminal uridylyl transferase 4
Synonyms: 6030404K05Rik, 9230115F04Rik, Tent3a, Zcchc11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230594
Homologene: 35279
Dcp2
Name: decapping mRNA 2
Synonyms: 2410015D23Rik, 5730537H01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 70640
Homologene: 13968
Mafg
Name: v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
Synonyms: C630022N07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17134
HGNC: HGNC:6781
Homologene: 81816
Rbm26
Name: RNA binding motif protein 26
Synonyms: Pro1777, C230097K14Rik, 1700009P03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 74213
Homologene: 41468
Ddx39a
Name: DEAD box helicase 39a
Synonyms: 2610307C23Rik, BAT1, Ddx39
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 68278
Homologene: 68487
Abr
Name: active BCR-related gene
Synonyms: 6330400K15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 109934
HGNC: HGNC:81
Homologene: 11081
Cdc45
Name: cell division cycle 45
Synonyms: Cdc45l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 12544
HGNC: HGNC:1739
Homologene: 2616
Ecpas
Name: Ecm29 proteasome adaptor and scaffold
Synonyms: AI314180
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230249
Homologene: 6056
Slc43a2
Name: solute carrier family 43, member 2
Synonyms: 7630402D21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 215113
Homologene: 17555
Dnah7a
Name: dynein, axonemal, heavy chain 7A
Synonyms: LOC381341, Dnahc7, Dnahc7a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 627872
Homologene: 41287
Dmbt1
Name: deleted in malignant brain tumors 1
Synonyms: CRP-[b], CRP-[a], ebnerin, hensin, vomeroglandin, Crpd, MUCLIN, gp300
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 12945
HGNC: HGNC:2926
Homologene: 68990
Hspd1
Name: heat shock protein 1 (chaperonin)
Synonyms: Hsp60
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 15510
HGNC: HGNC:5261
Homologene: 1626
Rab37
Name: RAB37, member RAS oncogene family
Synonyms: B230331O03Rik, B230354I04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 58222
Homologene: 23303
Galnt14
Name: polypeptide N-acetylgalactosaminyltransferase 14
Synonyms: 0610033M06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 71685
Homologene: 56997
Rnf115
Name: ring finger protein 115
Synonyms: 2610028E05Rik, Zfp364, Rabring7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 67845
Homologene: 69167
Emc1
Name: ER membrane protein complex subunit 1
Synonyms: C230096C10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230866
Homologene: 9002
Nbeal1
Name: neurobeachin like 1
Synonyms: A530050O19Rik, ALS2CR17, A530083I02Rik, 2310076G13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 269198
Homologene: 16453
Serpina10
Name: serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
Synonyms: PZI
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 217847
Homologene: 9414
Stk32b
Name: serine/threonine kinase 32B
Synonyms: 2510009F08Rik, YANK2, STKG6, Stk32
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 64293
Homologene: 48654
Cfap46
Name: cilia and flagella associated protein 46
Synonyms: 9330101J02Rik, Ttc40
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 212124
Tbx10
Name: T-box 10
Synonyms: Tbx7, Tbx13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 109575
VEGA: 19
Homologene: 37399
Tmprss7
Name: transmembrane serine protease 7
Synonyms: LOC385645, B230219I23Rik, matriptase-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 208171
Homologene: 18178
Cacna1d
Name: calcium channel, voltage-dependent, L type, alpha 1D subunit
Synonyms: D-LTCC, Cchl1a, Cchl1a2, Cacnl1a2, 8430418G19Rik, Cav1.3alpha1, C79217
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 12289
VEGA: 14
HGNC: HGNC:1391
Homologene: 578
Ryr3
Name: ryanodine receptor 3
Synonyms: calcium release channel isoform 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20192
Homologene: 68151
Mrgprb1
Name: MAS-related GPR, member B1
Synonyms: MrgB1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233231
Homologene: 24986
Nlrp2
Name: NLR family, pyrin domain containing 2
Synonyms: PYPAF2, E330007A02Rik, Nalp2, Pan1, Nbs1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 232827
Homologene: 56789
Klf17
Name: Kruppel-like factor 17
Synonyms: D4Ertd561e, 7420700M05Rik, Zfp393
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 75753
Homologene: 12621
Mtrf1l
Name: mitochondrial translational release factor 1-like
Synonyms: 9130004K12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 108853
Homologene: 5905
Ptprn
Name: protein tyrosine phosphatase, receptor type, N
Synonyms: IA-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 19275
HGNC: HGNC:9676
Homologene: 48142
Fcrl6
Name: Fc receptor-like 6
Synonyms: FcRH6, ENSMUSG00000070504, moFcRH6, mIFGP6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 677296
Homologene: 88414
Dpp7
Name: dipeptidylpeptidase 7
Synonyms: QPP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 83768
Homologene: 22748
Fam102a
Name: family with sequence similarity 102, member A
Synonyms: C230093N12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 98952
Homologene: 51943
Zfp352
Name: zinc finger protein 352
Synonyms: 2czf48
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 236537
Homologene: 45160
Slc6a9
Name: solute carrier family 6 (neurotransmitter transporter, glycine), member 9
Synonyms: Glyt-1, Glyt1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 14664
Homologene: 5050
Ccdc146
Name: coiled-coil domain containing 146
Synonyms: 4930528G09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 75172
Homologene: 67159
Ugt2a3
Name: UDP glucuronosyltransferase 2 family, polypeptide A3
Synonyms: 2010321J07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 72094
Homologene: 55988
Coq2
Name: coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
Synonyms: 2310002F18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 71883
Homologene: 69192
Syna
Name: syncytin a
Synonyms: syncytin-A, Gm52
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 214292
Homologene: 86751
Lnx2
Name: ligand of numb-protein X 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 140887
Homologene: 17737
Zfp775
Name: zinc finger protein 775
Synonyms: C130032F08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243372
Homologene: 37089
Zfp575
Name: zinc finger protein 575
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 101544
Homologene: 45485
6330444E15Rik
Name: RIKEN cDNA 6330444E15 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Odf3
Name: outer dense fiber of sperm tails 3
Synonyms: SHIPPO1, 1700011O04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 69287
Homologene: 12306
Rwdd4a
Name: RWD domain containing 4A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 192174
Homologene: 16059
Mrpl4
Name: mitochondrial ribosomal protein L4
Synonyms: 1110017G11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 66163
VEGA: 9
Homologene: 32286
Ecsit
Name: ECSIT signalling integrator
Synonyms: Sitpec
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 26940
Homologene: 8080
Nek11
Name: NIMA (never in mitosis gene a)-related expressed kinase 11
Synonyms: 4932416N14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 208583
Homologene: 57008
Dalrd3
Name: DALR anticodon binding domain containing 3
Synonyms: 6330580J24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 67789
Homologene: 32388
Stac3
Name: SH3 and cysteine rich domain 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 237611
Homologene: 17039
Naip1
Name: NLR family, apoptosis inhibitory protein 1
Synonyms: D13Lsd1, Naip, Birc1a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 17940
VEGA: 13
HGNC: HGNC:7634
Homologene: 113589
Impg2
Name: interphotoreceptor matrix proteoglycan 2
Synonyms: PG10.2, IPM200, Spacrcan
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224224
Homologene: 9439
Ankhd1
Name: ankyrin repeat and KH domain containing 1
Synonyms: 1110004O12Rik, 9130019P20Rik, 4933432B13Rik, A530027J04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 108857
Homologene: 87006
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to G, chromosome 1 at 53,521,086 bp
  • A to G, chromosome 1 at 55,082,046 bp
  • T to A, chromosome 1 at 60,310,263 bp
  • A to G, chromosome 1 at 75,252,254 bp
  • A to T, chromosome 1 at 172,598,753 bp
  • A to G, chromosome 2 at 25,356,095 bp
  • G to A, chromosome 2 at 32,558,053 bp
  • T to C, chromosome 2 at 112,869,075 bp
  • T to A, chromosome 2 at 164,986,663 bp
  • C to T, chromosome 2 at 181,350,656 bp
  • A to G, chromosome 3 at 96,785,022 bp
  • T to C, chromosome 3 at 116,885,297 bp
  • A to G, chromosome 4 at 58,832,729 bp
  • T to C, chromosome 4 at 90,224,285 bp
  • T to G, chromosome 4 at 108,527,004 bp
  • T to C, chromosome 4 at 117,760,392 bp
  • T to C, chromosome 4 at 117,864,859 bp
  • T to A, chromosome 4 at 139,375,163 bp
  • C to A, chromosome 5 at 21,316,904 bp
  • A to G, chromosome 5 at 37,459,596 bp
  • A to G, chromosome 5 at 38,320,614 bp
  • A to G, chromosome 5 at 87,337,006 bp
  • T to C, chromosome 5 at 100,663,685 bp
  • T to A, chromosome 5 at 118,742,655 bp
  • C to A, chromosome 5 at 125,281,100 bp
  • A to T, chromosome 5 at 134,559,543 bp
  • A to G, chromosome 5 at 147,029,353 bp
  • A to G, chromosome 6 at 48,620,772 bp
  • A to T, chromosome 7 at 5,322,334 bp
  • A to G, chromosome 7 at 24,586,087 bp
  • A to G, chromosome 7 at 29,579,101 bp
  • A to G, chromosome 7 at 48,447,214 bp
  • G to T, chromosome 7 at 131,119,496 bp
  • A to G, chromosome 7 at 139,676,035 bp
  • C to A, chromosome 7 at 140,850,221 bp
  • A to G, chromosome 8 at 47,537,365 bp
  • A to G, chromosome 8 at 83,720,622 bp
  • C to A, chromosome 8 at 122,889,742 bp
  • C to A, chromosome 9 at 21,007,668 bp
  • C to T, chromosome 9 at 22,076,288 bp
  • A to G, chromosome 9 at 105,218,539 bp
  • T to C, chromosome 9 at 108,572,215 bp
  • T to C, chromosome 10 at 5,813,382 bp
  • T to C, chromosome 10 at 5,813,384 bp
  • G to A, chromosome 10 at 127,508,148 bp
  • T to C, chromosome 11 at 75,562,850 bp
  • T to A, chromosome 11 at 76,472,502 bp
  • T to C, chromosome 11 at 115,158,665 bp
  • G to T, chromosome 11 at 120,629,604 bp
  • A to G, chromosome 12 at 103,626,897 bp
  • T to C, chromosome 13 at 100,411,001 bp
  • G to A, chromosome 14 at 30,111,095 bp
  • A to G, chromosome 14 at 87,037,454 bp
  • A to C, chromosome 14 at 105,152,540 bp
  • T to C, chromosome 15 at 89,369,664 bp
  • G to C, chromosome 16 at 4,947,749 bp
  • G to T, chromosome 16 at 18,794,774 bp
  • T to A, chromosome 16 at 20,193,724 bp
  • T to C, chromosome 16 at 45,673,939 bp
  • T to A, chromosome 16 at 56,258,048 bp
  • C to A, chromosome 17 at 73,507,859 bp
  • T to C, chromosome 18 at 36,647,188 bp
  • T to A, chromosome 18 at 44,405,374 bp
  • T to C, chromosome 19 at 3,996,798 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0051 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038345-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.