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Strain Name:
C57BL/6J-MtgxR0127Btlr/Mmmh
Stock Number:
038412-MU
Citation ID:
RRID:MMRRC_038412-MU
Other Names:
R0127 (G1), C57BL/6J-MtgxR0127Btlr
Major Collection:

Strain Information

Hapln1
Name: hyaluronan and proteoglycan link protein 1
Synonyms: link protein, cartilage linking protein 1, Crtl1l, Crtl1, CLP, LP-1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 12950
VEGA: 13
HGNC: HGNC:2380
Homologene: 1420
Slc12a1
Name: solute carrier family 12, member 1
Synonyms: Nkcc2, mBSC1, D630042G03Rik, urehr3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 20495
Homologene: 286
Mkrn1
Name: makorin, ring finger protein, 1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 54484
HGNC: HGNC:7112
Homologene: 32175
Ccdc88c
Name: coiled-coil domain containing 88C
Synonyms: Daple, 0610010D24Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 68339
VEGA: 12
Homologene: 18903
Cmtm7
Name: CKLF-like MARVEL transmembrane domain containing 7
Synonyms: Cklfsf7
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 102545
VEGA: 9
Homologene: 15882
Dock5
Name: dedicator of cytokinesis 5
Synonyms: lr2, 1110060D06Rik, rlc
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 68813
VEGA: 14
Homologene: 57016
Znfx1
Name: zinc finger, NFX1-type containing 1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 98999
Homologene: 10877
Dido1
Name: death inducer-obliterator 1
Synonyms: DIO-1, 6720461J16Rik, Datf1, D130048F08Rik, dido, C130092D22Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 23856
HGNC: HGNC:2680
Homologene: 34139
Cep290
Name: centrosomal protein 290
Synonyms: Nphp6, b2b1454Clo, b2b1752Clo, Kiaa
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216274
VEGA: 10
Homologene: 77213
Zc3h13
Name: zinc finger CCCH type containing 13
Synonyms: C87618, 4930570G11Rik, 2600010B19Rik, 3110050K21Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 67302
VEGA: 14
Tnpo2
Name: transportin 2 (importin 3, karyopherin beta 2b)
Synonyms: Kpnb2b, TRN2, 1110034O24Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 212999
Homologene: 8381
Zcchc8
Name: zinc finger, CCHC domain containing 8
Synonyms: 5730565F05Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 70650
Homologene: 32349
Tsc22d1
Name: TSC22 domain family, member 1
Synonyms: TSC-22, Egr5, Tgfb1i4
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 21807
Homologene: 7573
Heatr5a
Name: HEAT repeat containing 5A
Synonyms: D930036F22Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 320487
VEGA: 12
Homologene: 19635
Rtf1
Name: RTF1, Paf1/RNA polymerase II complex component
Synonyms: 6530416A09Rik, 2900005O08Rik, Gtl7
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 76246
Homologene: 133868
Abca1
Name: ATP-binding cassette, sub-family A member 1
Synonyms: ABC1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 11303
HGNC: HGNC:29
Homologene: 21130
Rffl
Name: ring finger and FYVE like domain containing protein
Synonyms: 4930516L10Rik, fring, rififylin, 1700051E09Rik, Carp-2, Carp2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 67338
Homologene: 12116
Krit1
Name: KRIT1, ankyrin repeat containing
Synonyms: Krit1, 2010007K12Rik, Krit1B, Krit1A, A630036P20Rik, Ccm1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 79264
HGNC: HGNC:1573
Homologene: 12746
Tonsl
Name: tonsoku-like, DNA repair protein
Synonyms: 2810439M11Rik, Nfkbil2
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 72749
HGNC: HGNC:7801
Homologene: 22754
Atp6v1b2
Name: ATPase, H+ transporting, lysosomal V1 subunit B2
Synonyms: HO57, Atp6b2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 11966
HGNC: HGNC:854
Homologene: 1279
Oga
Name: O-GlcNAcase
Synonyms: Hy5, 5830447M11Rik, 4833427O07Rik, 2810009A20Rik, Mgea5
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 76055
VEGA: 19
HGNC: HGNC:7056
Homologene: 8154
Muc2
Name: mucin 2
Synonyms: 2010015E03Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 17831
HGNC: HGNC:7512
Homologene: 136755
Syt17
Name: synaptotagmin XVII
Synonyms: Bk
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 110058
Homologene: 9553
Baz1a
Name: bromodomain adjacent to zinc finger domain 1A
Synonyms: Gtl5, Wcrf180, Acf1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217578
HGNC: HGNC:960
Homologene: 45654
Sptbn2
Name: spectrin beta, non-erythrocytic 2
Synonyms: Spnb3
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 20743
VEGA: 19
Homologene: 48482
Rrbp1
Name: ribosome binding protein 1
Synonyms: mRRp0, ES/130, p180, mRRp1.8, mRRp2, mRRp5.4, mRRp10, mRRp16.8, mRRp15b, mRRp15a, mRRp41, mRRp47, 1700087N07Rik, 5730465C04Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 81910
Homologene: 68138
Tars3
Name: threonyl-tRNA synthetase 3
Synonyms: A530046H20Rik, Tarsl2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 272396
Homologene: 65036
Slc35f5
Name: solute carrier family 35, member F5
Synonyms: 1300003P13Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 74150
Homologene: 5745
Bbs1
Name: Bardet-Biedl syndrome 1
Synonyms: D19Ertd609e
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 52028
VEGA: 19
HGNC: HGNC:966
Homologene: 11641
Dnah5
Name: dynein, axonemal, heavy chain 5
Synonyms: Mdnah5, b2b1537Clo, b2b1565Clo, b2b1154Clo, b2b1134Clo, Dnahc5, b2b3491Clo
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 110082
HGNC: HGNC:2950
Homologene: 1048
Ttn
Name: titin
Synonyms: connectin, L56, mdm, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Dnah6
Name: dynein, axonemal, heavy chain 6
Synonyms: A730004I20Rik, Dnahc6
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 330355
HGNC: HGNC:2951
Homologene: 15221
Fat2
Name: FAT atypical cadherin 2
Synonyms: LOC245827, mKIAA0811, Fath2, EMI2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 245827
HGNC: HGNC:3596
Homologene: 1110
Kmt5b
Name: lysine methyltransferase 5B
Synonyms: Suv4-20h1, C630029K18Rik, Suv420h1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 225888
Homologene: 32351
Mapre2
Name: microtubule-associated protein, RP/EB family, member 2
Synonyms: D18Abb1e, RP1, EB2, C820009F03Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 212307
HGNC: HGNC:6891
Homologene: 134539
Pkhd1l1
Name: polycystic kidney and hepatic disease 1-like 1
Synonyms: D86 mRNA, PKHDL1, fibrocystin L
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 192190
Homologene: 16332
Fsip2
Name: fibrous sheath-interacting protein 2
Synonyms: OTTMUSG00000013335
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241516
Homologene: 110349
Slc15a3
Name: solute carrier family 15, member 3
Synonyms: cI-1, Ci1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 65221
Homologene: 69222
Gm5114
Name: predicted gene 5114
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 330513
Homologene: 45597
Csmd3
Name: CUB and Sushi multiple domains 3
Synonyms: 4930500N14Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 239420
Homologene: 65982
Ankrd50
Name: ankyrin repeat domain 50
Synonyms: E430012K20Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99696
Homologene: 129859
Rmdn2
Name: regulator of microtubule dynamics 2
Synonyms: Fam82a1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 381110
VEGA: 17
Homologene: 71930
Il4ra
Name: interleukin 4 receptor, alpha
Synonyms: IL-4 receptor alpha chain, CD124, Il4r
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 16190
HGNC: HGNC:6015
Homologene: 7784
Nebl
Name: nebulette
Synonyms: Lnebl, 1200007O21Rik, A630080F05Rik, D830029A09Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 74103
Homologene: 128431
Fam234b
Name: family with sequence similarity 234, member B
Synonyms: 8430419L09Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 74525
Homologene: 12572
Serac1
Name: serine active site containing 1
Synonyms: 4930511N22Rik, D17Ertd141e
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 321007
Homologene: 41900
Slc28a2b
Name: solute carrier family 28 member 2b
Synonyms: Gm14085
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 381417
Prkch
Name: protein kinase C, eta
Synonyms: Pkch
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 18755
HGNC: HGNC:9403
Homologene: 84384
Thsd7a
Name: thrombospondin, type I, domain containing 7A
Synonyms: LOC330267
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 330267
Homologene: 46582
Lamp1
Name: lysosomal-associated membrane protein 1
Synonyms: CD107a, Lamp-1, Perk
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 16783
HGNC: HGNC:6499
Homologene: 4061
Vmn2r89
Name: vomeronasal 2, receptor 89
Synonyms: V2r11, V2r10
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 22301
Caskin2
Name: CASK-interacting protein 2
Synonyms: 1600028L06Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 140721
Homologene: 32485
Cyp26b1
Name: cytochrome P450, family 26, subfamily b, polypeptide 1
Synonyms: P450RAI-2, retinoic acid B1, CP26
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232174
Homologene: 23179
Or5w8
Name: olfactory receptor family 5 subfamily W member 8
Synonyms: GA_x6K02T2Q125-49358694-49359620, MOR177-9, Olfr1151
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258631
Homologene: 36999
Or4p18
Name: olfactory receptor family 4 subfamily P member 18
Synonyms: GA_x6K02T2Q125-49890854-49889931, MOR225-2, Olfr1179
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258919
Homologene: 74070
Wt1
Name: WT1 transcription factor
Synonyms: Wt-1, D630046I19Rik, Wilms tumor 1 homolog
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22431
Homologene: 11536
Spag4
Name: sperm associated antigen 4
Synonyms: 1700041K21Rik, Sun4
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 245865
Homologene: 2343
Zbtb46
Name: zinc finger and BTB domain containing 46
Synonyms: 4933406L05Rik, 2610019F01Rik, Btbd4
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 72147
Homologene: 81908
Dynlt5
Name: dynein light chain Tctex-type 5
Synonyms: 1700055O19Rik, Tctex1d1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 67344
Homologene: 12117
Col16a1
Name: collagen, type XVI, alpha 1
Synonyms: [a]1 (XVI) collagen, 2700007F12Rik, A530052M23Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 107581
HGNC: HGNC:2193
Homologene: 1397
Dao
Name: D-amino acid oxidase
Synonyms: DAO, Dao-1, Dao1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 13142
HGNC: HGNC:2671
Homologene: 37553
Pop5
Name: processing of precursor 5, ribonuclease P/MRP family (S. cerevisiae)
Synonyms: 1500019J17Rik, Rnasep3, 2700077E03Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 117109
Homologene: 41076
Cep89
Name: centrosomal protein 89
Synonyms: 2610507L03Rik, Ccdc123
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 72140
Homologene: 12444
Trim12c
Name: tripartite motif-containing 12C
Synonyms: Trim12-2, 9230105E10Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 319236
Homologene: 75345
Pkd1l2
Name: polycystic kidney disease 1 like 2
Synonyms: 1700126L06Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 76645
Homologene: 124481
Spire2
Name: spire type actin nucleation factor 2
Synonyms: Spir-2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234857
Homologene: 72212
Igsf9b
Name: immunoglobulin superfamily, member 9B
Synonyms: LOC235086, AI414108
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235086
Homologene: 19472
Or8g32
Name: olfactory receptor family 8 subfamily G member 32
Synonyms: GA_x6K02T2PVTD-33090395-33091330, MOR171-33P, MOR171-49, Olfr951
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258046
VEGA: 9
HGNC: HGNC:8484
Homologene: 71961
Slc35g2
Name: solute carrier family 35, member G2
Synonyms: LOC245020, Tmem22
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 245020
Homologene: 11893
Als2cl
Name: ALS2 C-terminal like
Synonyms: mRn.49018, D930044G19Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235633
Homologene: 17152
Vrk2
Name: vaccinia related kinase 2
Synonyms: 2810003O05Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 69922
Homologene: 55966
Acap1
Name: ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
Synonyms: Centb1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216859
Homologene: 22835
Dlx4
Name: distal-less homeobox 4
Synonyms: DII D, Dlx-4, Dlx7
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 13394
HGNC: HGNC:2917
Homologene: 7292
Bphl
Name: biphenyl hydrolase like
Synonyms: 2010012D11Rik, 5730533B08Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 68021
VEGA: 13
HGNC: HGNC:1094
Homologene: 55812
Or11g2
Name: olfactory receptor family 11 subfamily G member 2
Synonyms: GA_x6K02T2PMLR-6326342-6327313, MOR106-13P, Olfr744
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 257884
Homologene: 128063
Ugt3a2
Name: UDP glycosyltransferases 3 family, polypeptide A2
Synonyms: Ugt3a, Ugt3a1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 105887
Homologene: 122787
Krtap13-22
Name: keratin associated protein 13-22
Synonyms: 2310061N02Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 69661
Homologene: 130759
Cbr1
Name: carbonyl reductase 1
Synonyms: CR
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 12408
HGNC: HGNC:1548
Homologene: 37524
Ly6g5b
Name: lymphocyte antigen 6 family member G5B
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 266614
Homologene: 49666
Mep1a
Name: meprin 1 alpha
Synonyms: meprin A alpha-subunit, Mep-1a, Mep-1, meprin alpha, Mep1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 17287
HGNC: HGNC:7015
Homologene: 31323
Hps1
Name: HPS1, biogenesis of lysosomal organelles complex 3 subunit 1
Synonyms: 6030422N11Rik, Hermansky-Pudlak syndrome 1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 192236
HGNC: HGNC:5163
Homologene: 163
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 125,576,205 bp
  • T to A, chromosome 2 at 17,392,983 bp
  • T to C, chromosome 2 at 76,742,198 bp
  • T to A, chromosome 2 at 76,877,011 bp
  • T to A, chromosome 2 at 82,984,925 bp
  • A to G, chromosome 2 at 87,857,483 bp
  • A to G, chromosome 2 at 88,402,355 bp
  • C to A, chromosome 2 at 105,133,457 bp
  • G to A, chromosome 2 at 119,726,743 bp
  • T to A, chromosome 2 at 122,517,069 bp
  • A to G, chromosome 2 at 125,219,762 bp
  • C to T, chromosome 2 at 143,989,944 bp
  • T to C, chromosome 2 at 156,068,042 bp
  • T to C, chromosome 2 at 167,044,210 bp
  • T to C, chromosome 2 at 180,671,824 bp
  • G to A, chromosome 2 at 181,411,815 bp
  • T to C, chromosome 3 at 38,456,235 bp
  • A to G, chromosome 3 at 55,049,748 bp
  • T to C, chromosome 4 at 53,067,155 bp
  • T to C, chromosome 4 at 103,002,452 bp
  • T to A, chromosome 4 at 130,052,857 bp
  • A to G, chromosome 5 at 3,822,178 bp
  • T to C, chromosome 5 at 22,004,136 bp
  • T to A, chromosome 5 at 114,019,963 bp
  • T to A, chromosome 5 at 115,240,171 bp
  • C to G, chromosome 5 at 123,707,337 bp
  • A to G, chromosome 6 at 12,554,908 bp
  • A to G, chromosome 6 at 39,399,275 bp
  • T to A, chromosome 6 at 73,038,734 bp
  • A to G, chromosome 6 at 84,577,208 bp
  • T to C, chromosome 6 at 135,218,823 bp
  • C to A, chromosome 7 at 35,428,262 bp
  • T to C, chromosome 7 at 39,408,456 bp
  • A to T, chromosome 7 at 65,664,969 bp
  • A to G, chromosome 7 at 104,340,906 bp
  • T to A, chromosome 7 at 118,409,941 bp
  • G to T, chromosome 7 at 125,569,070 bp
  • C to A, chromosome 7 at 141,748,954 bp
  • T to C, chromosome 8 at 13,174,491 bp
  • T to A, chromosome 8 at 69,103,460 bp
  • T to C, chromosome 8 at 85,040,628 bp
  • A to G, chromosome 8 at 117,050,048 bp
  • A to C, chromosome 8 at 123,358,097 bp
  • G to T, chromosome 9 at 27,334,385 bp
  • A to G, chromosome 9 at 39,393,942 bp
  • C to T, chromosome 9 at 100,553,117 bp
  • T to C, chromosome 9 at 110,891,867 bp
  • T to C, chromosome 9 at 114,781,670 bp
  • T to A, chromosome 10 at 100,536,925 bp
  • G to T, chromosome 11 at 26,534,313 bp
  • T to C, chromosome 11 at 55,289,286 bp
  • A to T, chromosome 11 at 69,887,217 bp
  • G to A, chromosome 11 at 82,812,632 bp
  • T to G, chromosome 11 at 95,141,229 bp
  • C to A, chromosome 11 at 115,800,994 bp
  • A to G, chromosome 12 at 51,925,405 bp
  • T to A, chromosome 12 at 54,898,706 bp
  • C to A, chromosome 12 at 73,721,787 bp
  • T to C, chromosome 12 at 100,935,740 bp
  • A to G, chromosome 13 at 34,064,046 bp
  • A to T, chromosome 13 at 89,607,869 bp
  • A to G, chromosome 14 at 50,618,332 bp
  • A to G, chromosome 14 at 51,455,703 bp
  • A to T, chromosome 14 at 67,846,042 bp
  • A to T, chromosome 14 at 75,323,254 bp
  • A to G, chromosome 14 at 76,418,981 bp
  • T to C, chromosome 15 at 9,306,256 bp
  • C to T, chromosome 15 at 28,294,925 bp
  • A to G, chromosome 15 at 44,554,605 bp
  • T to C, chromosome 15 at 47,981,930 bp
  • G to T, chromosome 15 at 76,633,485 bp
  • T to C, chromosome 16 at 88,707,454 bp
  • C to A, chromosome 16 at 93,609,987 bp
  • G to T, chromosome 17 at 6,048,840 bp
  • A to G, chromosome 17 at 35,114,591 bp
  • A to G, chromosome 17 at 43,497,886 bp
  • A to T, chromosome 17 at 79,670,569 bp
  • A to G, chromosome 18 at 23,804,175 bp
  • A to G, chromosome 19 at 3,786,465 bp
  • G to T, chromosome 19 at 4,724,744 bp
  • A to T, chromosome 19 at 4,895,029 bp
  • T to A, chromosome 19 at 10,855,986 bp
  • A to G, chromosome 19 at 42,771,111 bp
  • A to T, chromosome 19 at 45,771,888 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0127 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
038412-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.