Strain Name:
C57BL/6J-MtgxR0409Btlr/Mmmh
Stock Number:
038611-MU
Citation ID:
RRID:MMRRC_038611-MU
Other Names:
R0409 (G1), C57BL/6J-MtgxR0409Btlr
Major Collection:

Gene Information

Utrn
Name: utrophin
Synonyms: G-utrophin, Dmdl, DRP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 22288
VEGA: 10
Homologene: 21398
Colgalt2
Name: collagen beta(1-O)galactosyltransferase 2
Synonyms: Glt25d2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 269132
Homologene: 22865
Il21r
Name: interleukin 21 receptor
Synonyms: NILR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 60504
HGNC: HGNC:6006
Homologene: 11040
Rnf10
Name: ring finger protein 10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 50849
Homologene: 40990
Birc2
Name: baculoviral IAP repeat-containing 2
Synonyms: mcIAP1, MIAP1, IAP1, MIHB, Api1, cIAP1, cIAP-1, HIAP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 11797
HGNC: HGNC:590
Homologene: 900
Vps13c
Name: vacuolar protein sorting 13C
Synonyms: C230055H22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 320528
VEGA: 9
Homologene: 41188
Nup93
Name: nucleoporin 93
Synonyms: 2410008G02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 71805
Homologene: 40971
Cep104
Name: centrosomal protein 104
Synonyms: BC046331
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230967
Homologene: 44919
Rev1
Name: REV1, DNA directed polymerase
Synonyms: REV1, 1110027I23Rik, Rev1l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 56210
Homologene: 32309
Cdc40
Name: cell division cycle 40
Synonyms: PRP17, EHB3, 1200003H23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 71713
VEGA: 10
Homologene: 5716
Hectd1
Name: HECT domain E3 ubiquitin protein ligase 1
Synonyms: A630086P08Rik, opm, b2b327Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 207304
VEGA: 12
Homologene: 9115
Cnot1
Name: CCR4-NOT transcription complex, subunit 1
Synonyms: 6030411K04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234594
HGNC: HGNC:7877
Homologene: 9453
Mlh3
Name: mutL homolog 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 217716
VEGA: 12
HGNC: HGNC:7128
Homologene: 91153
Sec23b
Name: SEC23 homolog B, COPII coat complex component
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 27054
Homologene: 74571
Ei24
Name: etoposide induced 2.4 mRNA
Synonyms: PIG8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 13663
Homologene: 3588
Map2
Name: microtubule-associated protein 2
Synonyms: MAP-2, G1-397-34, Mtap2, repro4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 17756
HGNC: HGNC:6839
Homologene: 1779
Gmfb
Name: glia maturation factor, beta
Synonyms: 3110001O16Rik, 3110001H22Rik, D14Ertd630e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 63985
HGNC: HGNC:4373
Homologene: 37882
Noc3l
Name: NOC3 like DNA replication regulator
Synonyms: Fad24
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 57753
VEGA: 19
Homologene: 39642
Fnip1
Name: folliculin interacting protein 1
Synonyms: A730024A03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216742
Homologene: 28173
Eps8l2
Name: EPS8-like 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 98845
Homologene: 69358
Prkcb
Name: protein kinase C, beta
Synonyms: Pkcb, A130082F03Rik, PKC-Beta, Prkcb2, Prkcb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18751
HGNC: HGNC:9395
Homologene: 56424
Trp73
Name: transformation related protein 73
Synonyms: p73, deltaNp73, TAp73
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 22062
Homologene: 3960
Exph5
Name: exophilin 5
Synonyms: slac2-b, B130009M24Rik, AC079869.22gm5, Slac2b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 320051
Homologene: 9007
Sdk2
Name: sidekick cell adhesion molecule 2
Synonyms: 5330435L01Rik, 4632412F08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237979
Homologene: 10406
Fsd1l
Name: fibronectin type III and SPRY domain containing 1-like
Synonyms: A230072O16Rik, Csdufd1, Ccdc10, Fsd1nl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 319636
Homologene: 45825
Snapc4
Name: small nuclear RNA activating complex, polypeptide 4
Synonyms: 5730436L13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227644
Homologene: 2321
Gm872
Name: predicted gene 872
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Gsap
Name: gamma-secretase activating protein
Synonyms: A530088I07Rik, Pion
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 212167
Homologene: 45504
Fat4
Name: FAT atypical cadherin 4
Synonyms: 6030410K14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 329628
Homologene: 14377
Trim80
Name: tripartite motif-containing 80
Synonyms: 4933422H20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 432613
Homologene: 46325
Lrrc7
Name: leucine rich repeat containing 7
Synonyms: densin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 242274
Homologene: 10817
1700022I11Rik
Name: RIKEN cDNA 1700022I11 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 67317
Homologene: 52406
Aox2
Name: aldehyde oxidase 2
Synonyms: Aox3l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 213043
Homologene: 84622
Pls1
Name: plastin 1 (I-isoform)
Synonyms: I-fimbrin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 102502
HGNC: HGNC:9090
Homologene: 68270
Rnpepl1
Name: arginyl aminopeptidase (aminopeptidase B)-like 1
Synonyms: 1110014H17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 108657
Homologene: 36367
Ccdc81
Name: coiled-coil domain containing 81
Synonyms: 4921513D09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 70884
Homologene: 128447
Faxc
Name: failed axon connections homolog
Synonyms: 6230409E13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 76132
Homologene: 32781
Disp3
Name: dispatched RND transporter family member 3
Synonyms: G630052C06Rik, Ptchd2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242748
Homologene: 25712
Sema5a
Name: sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
Synonyms: M-Sema D, semF, Semaf, 9130201M22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 20356
VEGA: 15
Homologene: 2949
Fbxo43
Name: F-box protein 43
Synonyms: 4930533G20Rik, XErp1 homolog, endogenous meiotic inhibitor 2, Emi2, early mitotic inhibitor 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 78803
VEGA: 15
Homologene: 66393
1700113H08Rik
Name: RIKEN cDNA 1700113H08 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 76640
Homologene: 45695
Olfr1036
Name: olfactory receptor 1036
Synonyms: GA_x6K02T2Q125-47549689-47550621, MOR245-25, MOR262-13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258245
4933417A18Rik
Name: RIKEN cDNA 4933417A18 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 66761
Homologene: 23555
Nacad
Name: NAC alpha domain containing
Synonyms: mKIAA0363
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 192950
Homologene: 135717
Olfr474
Name: olfactory receptor 474
Synonyms: GA_x6K02T2PBJ9-10283869-10284801, MOR204-20
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258488
Tctn3
Name: tectonic family member 3
Synonyms: Tect3, 4930521E07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 67590
Homologene: 9221
Olfr889
Name: olfactory receptor 889
Synonyms: GA_x6K02T2PVTD-31795028-31795957, MOR162-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258475
Homologene: 138311
Gm6420
Name: predicted gene 6420
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alkbh3
Name: alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase
Synonyms: 1700108H04Rik, Abh3, 1810020C19Rik, mABH3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 69113
Homologene: 16393
Gm4540
Name: predicted gene 4540
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 100043594
Chil6
Name: chitinase-like 6
Synonyms: BYm, BC051070
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229688
Homologene: 77638
Tfpt
Name: TCF3 (E2A) fusion partner
Synonyms: 2400004F01Rik, Amida, FB1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 69714
Homologene: 8349
Car7
Name: carbonic anhydrase 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 12354
HGNC: HGNC:1381
Homologene: 55875
Gm8801
Name: predicted gene 8801
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 667766
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to C, chromosome 1 at 23,256,038 bp
  • A to T, chromosome 1 at 38,074,368 bp
  • A to T, chromosome 1 at 58,336,624 bp
  • A to G, chromosome 1 at 66,433,580 bp
  • A to G, chromosome 1 at 92,915,860 bp
  • G to T, chromosome 1 at 152,508,561 bp
  • C to A, chromosome 2 at 26,367,216 bp
  • T to A, chromosome 2 at 86,075,302 bp
  • T to A, chromosome 2 at 94,001,448 bp
  • T to A, chromosome 2 at 144,567,912 bp
  • C to T, chromosome 3 at 38,977,413 bp
  • A to G, chromosome 3 at 106,034,966 bp
  • C to T, chromosome 3 at 106,404,176 bp
  • A to G, chromosome 3 at 158,161,426 bp
  • T to A, chromosome 4 at 21,948,751 bp
  • A to C, chromosome 4 at 42,972,203 bp
  • T to C, chromosome 4 at 53,679,932 bp
  • T to G, chromosome 4 at 148,271,959 bp
  • C to T, chromosome 4 at 153,983,053 bp
  • T to A, chromosome 4 at 154,064,384 bp
  • G to A, chromosome 5 at 21,222,445 bp
  • A to T, chromosome 5 at 115,255,447 bp
  • G to A, chromosome 7 at 3,620,899 bp
  • A to G, chromosome 7 at 89,886,215 bp
  • T to C, chromosome 7 at 107,955,226 bp
  • A to T, chromosome 7 at 122,424,977 bp
  • G to T, chromosome 7 at 125,629,840 bp
  • A to G, chromosome 7 at 141,342,980 bp
  • A to G, chromosome 8 at 94,303,665 bp
  • T to C, chromosome 8 at 95,748,855 bp
  • G to A, chromosome 8 at 104,548,424 bp
  • A to C, chromosome 9 at 7,819,384 bp
  • A to G, chromosome 9 at 36,786,477 bp
  • C to T, chromosome 9 at 38,116,251 bp
  • C to A, chromosome 9 at 53,374,343 bp
  • T to A, chromosome 9 at 67,951,644 bp
  • A to T, chromosome 9 at 95,786,919 bp
  • G to T, chromosome 10 at 12,643,601 bp
  • G to T, chromosome 10 at 40,847,168 bp
  • G to T, chromosome 10 at 87,225,954 bp
  • C to A, chromosome 10 at 92,776,213 bp
  • T to C, chromosome 11 at 6,599,810 bp
  • A to G, chromosome 11 at 54,480,354 bp
  • T to C, chromosome 11 at 113,850,891 bp
  • T to C, chromosome 11 at 115,441,213 bp
  • T to A, chromosome 12 at 51,782,556 bp
  • A to G, chromosome 12 at 85,240,854 bp
  • A to T, chromosome 13 at 34,924,549 bp
  • T to C, chromosome 14 at 46,816,222 bp
  • A to T, chromosome 15 at 32,681,609 bp
  • C to T, chromosome 15 at 36,162,357 bp
  • T to G, chromosome 17 at 35,947,376 bp
  • A to G, chromosome 19 at 38,817,927 bp
  • T to C, chromosome 19 at 40,611,416 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0409 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038611-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.