Strain Name:
C57BL/6J-MtgxR0446Btlr/Mmmh
Stock Number:
038647-MU
Citation ID:
RRID:MMRRC_038647-MU
Other Names:
R0446 (G1), C57BL/6J-MtgxR0446Btlr
Major Collection:

Gene Information

Lyst
Name: lysosomal trafficking regulator
Synonyms: D13Sfk13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 17101
VEGA: 13
HGNC: HGNC:1968
Homologene: 61
Emx2
Name: empty spiracles homeobox 2
Synonyms: Pdo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 13797
HGNC: HGNC:3341
Homologene: 3023
Kmt2e
Name: lysine (K)-specific methyltransferase 2E
Synonyms: 9530077A04Rik, 1810033J14Rik, D230038D11Rik, Mll5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 69188
Homologene: 18822
Pdzd2
Name: PDZ domain containing 2
Synonyms: Gm21706, 4930537L06Rik, LOC223364, Pdzk3, A930022H17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 68070
Homologene: 23393
Fryl
Name: FRY like transcription coactivator
Synonyms: 2510002A14Rik, 2310004H21Rik, 9030227G01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 72313
Homologene: 103956
Enpp2
Name: ectonucleotide pyrophosphatase/phosphodiesterase 2
Synonyms: Npps2, Pdnp2, PD-Ialpha, Autotaxin, ATX
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 18606
HGNC: HGNC:3357
Homologene: 4526
Trmt13
Name: tRNA methyltransferase 13
Synonyms: A930028L21Rik, 4631408H19Rik, Ccdc76
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229780
Homologene: 6875
Lmnb1
Name: lamin B1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 16906
HGNC: HGNC:6637
Homologene: 55912
Rbfox2
Name: RNA binding protein, fox-1 homolog (C. elegans) 2
Synonyms: Fxh, Rbm9, Fbm2, 2810460A15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 93686
VEGA: 15
HGNC: HGNC:9906
Homologene: 49375
Diaph1
Name: diaphanous related formin 1
Synonyms: p140mDia, mDia1, Diap1, Dia1, D18Wsu154e, Drf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 13367
HGNC: HGNC:2876
Homologene: 129567
Uvrag
Name: UV radiation resistance associated gene
Synonyms: Uvragl, 9530039D02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 78610
Homologene: 31150
Polr1a
Name: polymerase (RNA) I polypeptide A
Synonyms: mRPA1, 2900087K15Rik, 3010014K16Rik, RPA194, 194kDa, Rpo1-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 20019
Homologene: 7033
Usp34
Name: ubiquitin specific peptidase 34
Synonyms: A530081C03Rik, Murr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17847
Homologene: 40978
Orc5
Name: origin recognition complex, subunit 5
Synonyms: Orc5l, MmORC5, mouse origin recognition complex 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 26429
HGNC: HGNC:8491
Homologene: 37636
Cog7
Name: component of oligomeric golgi complex 7
Synonyms: 5630400E24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233824
Homologene: 33431
Gm14124
Name: predicted gene 14124
Synonyms: Gm10749, EG640962
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 100216455
Homologene: 134546
Cpsf4
Name: cleavage and polyadenylation specific factor 4
Synonyms: 30kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 54188
HGNC: HGNC:2327
Homologene: 38216
Bag1
Name: BCL2-associated athanogene 1
Synonyms: Rap46
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 12017
HGNC: HGNC:937
Homologene: 3190
Neurod6
Name: neurogenic differentiation 6
Synonyms: Nex, Math-2, Nex1m, Atoh2, Math2, bHLHa2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 11922
Homologene: 7632
Cuzd1
Name: CUB and zona pellucida-like domains 1
Synonyms: UTCZP, UO-44, ERG-1, Itmap1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 16433
Homologene: 7389
Cdc37
Name: cell division cycle 37
Synonyms: p50Cdc37
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12539
VEGA: 9
HGNC: HGNC:1735
Homologene: 38268
Mkln1
Name: muskelin 1, intracellular mediator containing kelch motifs
Synonyms: A130067F06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 27418
HGNC: HGNC:7109
Homologene: 8305
Ubr2
Name: ubiquitin protein ligase E3 component n-recognin 2
Synonyms: E130209G04Rik, 9930021A08Rik, ENSMUSG00000043296
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224826
VEGA: 17
Homologene: 26151
Dapk1
Name: death associated protein kinase 1
Synonyms: 2310039H24Rik, 2810425C21Rik, D13Ucla1, DAP-Kinase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 69635
VEGA: 13
HGNC: HGNC:2674
Homologene: 3626
Tbc1d32
Name: TBC1 domain family, member 32
Synonyms: C6orf170, D630037F22Rik, Bromi, b2b2284Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 544696
VEGA: 10
Homologene: 51889
Brip1
Name: BRCA1 interacting protein C-terminal helicase 1
Synonyms: 8030460J03Rik, BACH1, 3110009N10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237911
Homologene: 32766
Cdipt
Name: CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
Synonyms: D7Bwg0575e, 9530042F15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 52858
HGNC: HGNC:1769
Homologene: 7159
Cmya5
Name: cardiomyopathy associated 5
Synonyms: 2310076E16Rik, Myospryn, 2310076E21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 76469
VEGA: 13
Homologene: 137367
Casp1
Name: caspase 1
Synonyms: Caspase-1, Il1bc, ICE, interleukin 1 beta-converting enzyme
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12362
VEGA: 9
HGNC: HGNC:1499
Homologene: 133272
Svep1
Name: sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
Synonyms: Polydom, 4833413O10Rik, 1110021D17Rik, D430029O09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 64817
Homologene: 23386
Pkd1l3
Name: polycystic kidney disease 1 like 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 244646
Homologene: 14627
Fam160b1
Name: family with sequence similarity 160, member B1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 226252
VEGA: 19
Homologene: 28133
Avl9
Name: AVL9 cell migration associated
Synonyms: 5830411G16Rik, D730049P16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 78937
Homologene: 62425
Naip2
Name: NLR family, apoptosis inhibitory protein 2
Synonyms: Naip2, Birc1b, Naip-rs6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 17948
HGNC: HGNC:7634
Homologene: 136092
Zfand4
Name: zinc finger, AN1-type domain 4
Synonyms: Anubl1, 2810002D23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 67492
VEGA: 6
Homologene: 18373
Fbxw26
Name: F-box and WD-40 domain protein 26
Synonyms: Gm5163
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 382109
Homologene: 110776
Zan
Name: zonadhesin
Synonyms: Zan
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 22635
Homologene: 124417
Nlrp12
Name: NLR family, pyrin domain containing 12
Synonyms: Nalp12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 378425
Homologene: 16972
Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms: OTTMUSG00000005786, LOC380698
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 380698
Homologene: 70869
Olfr1346
Name: olfactory receptor 1346
Synonyms: GA_x6K02T2QGBW-3203957-3204898, MOR103-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258918
Homologene: 74134
Mdm1
Name: transformed mouse 3T3 cell double minute 1
Synonyms: Mdm-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 17245
VEGA: 10
Homologene: 9692
Map3k13
Name: mitogen-activated protein kinase kinase kinase 13
Synonyms: C130026N12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 71751
VEGA: 16
HGNC: HGNC:6852
Homologene: 37958
Krt20
Name: keratin 20
Synonyms: cytokeratin 20, 9030623C06Rik, CK20
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 66809
Homologene: 56837
Slc6a19
Name: solute carrier family 6 (neurotransmitter transporter), member 19
Synonyms: B0AT1, 4632401C08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 74338
Homologene: 52819
Olfr1153
Name: olfactory receptor 1153
Synonyms: GA_x6K02T2Q125-49395950-49396882, MOR177-7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258633
Homologene: 27230
Notch4
Name: notch 4
Synonyms: Int3, N4, Int-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 18132
HGNC: HGNC:7884
Homologene: 3351
Olfr920
Name: olfactory receptor 920
Synonyms: GA_x6K02T2PVTD-32458442-32459374, MOR165-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258783
VEGA: 9
Gss
Name: glutathione synthetase
Synonyms: GS-A/GS-B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14854
HGNC: HGNC:4624
Homologene: 148
Tex55
Name: testis expressed 55
Synonyms: 4930435E12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 74663
Homologene: 17614
1110051M20Rik
Name: RIKEN cDNA 1110051M20 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228356
Homologene: 11471
Gad1-ps
Name: glutamate decarboxylase 1, pseudogene
Synonyms: Gad-1ps
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 382407
VEGA: 10
Myrf
Name: myelin regulatory factor
Synonyms: LOC386531, Gm98, LOC225908
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 225908
HGNC: HGNC:1181
Homologene: 32167
B3galt4
Name: UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
Synonyms: Gal-T2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 54218
HGNC: HGNC:919
Homologene: 2805
Slc23a2
Name: solute carrier family 23 (nucleobase transporters), member 2
Synonyms: SVCT2, YSPL3, Slc23a1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 54338
Homologene: 68440
Pltp
Name: phospholipid transfer protein
Synonyms: Bpife, OD107
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18830
HGNC: HGNC:9093
Homologene: 4536
Actr3b
Name: ARP3 actin-related protein 3B
Synonyms: ARP11, Arp3b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 242894
Homologene: 4180
Rftn2
Name: raftlin family member 2
Synonyms: 2700010E02Rik, 3222401M22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 74013
Homologene: 16954
1700094D03Rik
Name: RIKEN cDNA 1700094D03 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 73545
VEGA: 3
Homologene: 78671
Mrgprb3
Name: MAS-related GPR, member B3
Synonyms: MrgB3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 404238
Homologene: 138632
Olfr480
Name: olfactory receptor 480
Synonyms: MOR204-32, GA_x6K02T2PBJ9-10395807-10394869
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 56861
Homologene: 72039
Olfr522
Name: olfactory receptor 522
Synonyms: GA_x6K02T2PBJ9-42315125-42314187, MOR103-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258954
Homologene: 62435
Olfr958
Name: olfactory receptor 958
Synonyms: MOR224-9, GA_x6K02T2PVTD-33247839-33246901
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258327
VEGA: 9
Homologene: 27128
Tmem25
Name: transmembrane protein 25
Synonyms: 0610039J01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 71687
Homologene: 12403
Pccb
Name: propionyl Coenzyme A carboxylase, beta polypeptide
Synonyms: 1300012P06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 66904
HGNC: HGNC:8654
Homologene: 447
Prss42
Name: protease, serine 42
Synonyms: Tessp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235628
Homologene: 27410
S1pr4
Name: sphingosine-1-phosphate receptor 4
Synonyms: Edg6, S1P4, lpC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 13611
VEGA: 10
HGNC: HGNC:3170
Homologene: 2799
Klhdc1
Name: kelch domain containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 271005
Homologene: 18155
Tigit
Name: T cell immunoreceptor with Ig and ITIM domains
Synonyms: Vstm3, ENSMUSG00000071552
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 100043314
VEGA: 16
Homologene: 18358
Fam170a
Name: family with sequence similarity 170, member A
Synonyms: LOC225497, Znfd
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225497
VEGA: 18
Homologene: 86702
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 55,214,195 bp
  • T to C, chromosome 2 at 87,896,855 bp
  • G to A, chromosome 2 at 91,304,764 bp
  • T to C, chromosome 2 at 132,078,433 bp
  • A to G, chromosome 2 at 150,268,073 bp
  • T to C, chromosome 2 at 155,567,745 bp
  • A to T, chromosome 2 at 164,854,400 bp
  • A to G, chromosome 3 at 90,064,459 bp
  • G to A, chromosome 3 at 116,582,626 bp
  • G to A, chromosome 4 at 40,936,609 bp
  • C to T, chromosome 4 at 58,088,280 bp
  • C to T, chromosome 5 at 22,546,457 bp
  • T to A, chromosome 5 at 23,497,534 bp
  • T to A, chromosome 5 at 25,831,732 bp
  • G to A, chromosome 5 at 73,097,417 bp
  • T to A, chromosome 5 at 137,391,658 bp
  • T to A, chromosome 5 at 145,177,244 bp
  • T to A, chromosome 6 at 31,449,504 bp
  • C to T, chromosome 6 at 55,679,629 bp
  • G to T, chromosome 6 at 56,736,483 bp
  • T to C, chromosome 6 at 71,950,664 bp
  • C to T, chromosome 6 at 116,288,054 bp
  • T to C, chromosome 7 at 3,234,029 bp
  • T to C, chromosome 7 at 6,475,025 bp
  • A to G, chromosome 7 at 48,643,236 bp
  • T to A, chromosome 7 at 98,906,485 bp
  • A to T, chromosome 7 at 108,066,725 bp
  • T to C, chromosome 7 at 121,937,072 bp
  • A to G, chromosome 7 at 126,978,264 bp
  • A to T, chromosome 7 at 131,316,280 bp
  • A to T, chromosome 7 at 140,162,471 bp
  • C to G, chromosome 8 at 109,623,649 bp
  • A to G, chromosome 9 at 5,306,662 bp
  • T to C, chromosome 9 at 21,142,542 bp
  • G to T, chromosome 9 at 38,755,818 bp
  • A to T, chromosome 9 at 39,550,451 bp
  • T to C, chromosome 9 at 44,796,581 bp
  • T to C, chromosome 9 at 100,982,797 bp
  • A to G, chromosome 9 at 109,743,720 bp
  • G to A, chromosome 9 at 110,799,273 bp
  • T to A, chromosome 10 at 56,192,898 bp
  • A to T, chromosome 10 at 81,498,989 bp
  • C to A, chromosome 10 at 99,445,521 bp
  • T to G, chromosome 10 at 118,152,056 bp
  • A to G, chromosome 11 at 23,467,207 bp
  • A to T, chromosome 11 at 58,995,412 bp
  • A to T, chromosome 11 at 86,157,601 bp
  • G to A, chromosome 11 at 99,437,776 bp
  • A to C, chromosome 12 at 69,283,308 bp
  • T to A, chromosome 13 at 13,638,048 bp
  • T to A, chromosome 13 at 60,725,287 bp
  • T to C, chromosome 13 at 73,691,695 bp
  • T to A, chromosome 13 at 93,093,656 bp
  • A to C, chromosome 13 at 100,161,782 bp
  • A to T, chromosome 15 at 12,375,024 bp
  • T to C, chromosome 15 at 54,910,027 bp
  • A to T, chromosome 15 at 77,099,255 bp
  • T to A, chromosome 16 at 21,921,555 bp
  • G to A, chromosome 16 at 38,828,702 bp
  • G to T, chromosome 16 at 43,662,271 bp
  • T to C, chromosome 17 at 33,951,018 bp
  • C to T, chromosome 17 at 34,565,363 bp
  • A to T, chromosome 17 at 46,983,298 bp
  • A to G, chromosome 18 at 37,853,590 bp
  • T to A, chromosome 18 at 50,280,632 bp
  • T to A, chromosome 18 at 56,743,259 bp
  • G to C, chromosome 19 at 10,218,162 bp
  • G to A, chromosome 19 at 57,381,407 bp
  • A to T, chromosome 19 at 59,463,916 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0446 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038647-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.