Strain Name:
C57BL/6J-MtgxR0879Btlr/Mmmh
Stock Number:
039046-MU
Citation ID:
RRID:MMRRC_039046-MU
Other Names:
R0879 (G1), C57BL/6J-MtgxR0879Btlr
Major Collection:

Gene Information

Fgd4
Name: FYVE, RhoGEF and PH domain containing 4
Synonyms: Frabin-gamma, Frabin-beta, Frabin-alpha, Frabin, 9330209B17Rik, ZFYVE6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224014
Homologene: 26727
Pelp1
Name: proline, glutamic acid and leucine rich protein 1
Synonyms: 4930563C04Rik, MNAR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 75273
Homologene: 8664
Enpp2
Name: ectonucleotide pyrophosphatase/phosphodiesterase 2
Synonyms: Autotaxin, Npps2, PD-Ialpha, Pdnp2, ATX
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 18606
HGNC: HGNC:3357
Homologene: 4526
Baz2a
Name: bromodomain adjacent to zinc finger domain, 2A
Synonyms: Tip5, Walp3, C030005G16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 116848
VEGA: 10
HGNC: HGNC:962
Homologene: 8393
Brd2
Name: bromodomain containing 2
Synonyms: Ring3, Frg-1, D17H6S113E, Fsrg1, Rnf3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 14312
HGNC: HGNC:1103
Homologene: 74540
Zfp292
Name: zinc finger protein 292
Synonyms: Zn-16, Zn-15, Krox-10, Zfp-15, 9430062L07Rik, 5730450D02Rik, Zfp15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 30046
Homologene: 8493
Dnah7a
Name: dynein, axonemal, heavy chain 7A
Synonyms: LOC381341, Dnahc7, Dnahc7a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 627872
Homologene: 41287
Npas4
Name: neuronal PAS domain protein 4
Synonyms: LE-PAS, Nxf, Npas4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 225872
VEGA: 19
Homologene: 15333
C6
Name: complement component 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 12274
HGNC: HGNC:1339
Homologene: 47
Aagab
Name: alpha- and gamma-adaptin binding protein
Synonyms: 2310007F21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 66939
VEGA: 9
Homologene: 11648
Stk32b
Name: serine/threonine kinase 32B
Synonyms: 2510009F08Rik, YANK2, STKG6, Stk32
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 64293
Homologene: 48654
Stra6
Name: stimulated by retinoic acid gene 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 20897
Homologene: 7554
Zp2
Name: zona pellucida glycoprotein 2
Synonyms: Zp-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 22787
Homologene: 48194
Jag1
Name: jagged 1
Synonyms: Serrate-1, Headturner, Htu, ABE2, Ozz, Gsfabe2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 16449
HGNC: HGNC:6188
Homologene: 180
Ltbr
Name: lymphotoxin B receptor
Synonyms: TNFRrp, TNF receptor-related protein, LT-beta receptor, LT beta-R, Tnfbr, Ltar, TNF-R-III, TNFCR, TNFR2-RP, LTbetaR, Tnfrsf3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 17000
HGNC: HGNC:6718
Homologene: 1753
Akap6
Name: A kinase (PRKA) anchor protein 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238161
VEGA: 12
HGNC: HGNC:376
Homologene: 3157
Dnah17
Name: dynein, axonemal, heavy chain 17
Synonyms: LOC382552, 2810003K23Rik, Dnahcl1, Dnahc17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 69926
HGNC: HGNC:2946
Homologene: 72102
Col7a1
Name: collagen, type VII, alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12836
HGNC: HGNC:2214
Homologene: 73
Wdr17
Name: WD repeat domain 17
Synonyms: 3010002I12Rik, B230207L18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 244484
Homologene: 12460
Ryr3
Name: ryanodine receptor 3
Synonyms: calcium release channel isoform 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20192
Homologene: 68151
Vmn1r76
Name: vomeronasal 1 receptor 76
Synonyms: V1rg4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 171239
Usp17le
Name: ubiquitin specific peptidase 17-like E
Synonyms: Gm6596, Dub3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 625530
Homologene: 131315
Vmn2r102
Name: vomeronasal 2, receptor 102
Synonyms: EG224572
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224572
Homologene: 115024
Selenbp2
Name: selenium binding protein 2
Synonyms: acetaminophen-binding protein, AP56, Lpsb2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 20342
Homologene: 2930
Megf8
Name: multiple EGF-like-domains 8
Synonyms: Egfl4, b2b288Clo, b2b1702Clo, m687Ddg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 269878
HGNC: HGNC:3233
Homologene: 15988
Mybpc1
Name: myosin binding protein C, slow-type
Synonyms: Slow-type C-protein, 8030451F13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 109272
HGNC: HGNC:7549
Homologene: 1846
Eml6
Name: echinoderm microtubule associated protein like 6
Synonyms: 2900083P10Rik, C230094A16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237711
Homologene: 104282
Igsf9b
Name: immunoglobulin superfamily, member 9B
Synonyms: LOC235086, AI414108
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235086
Homologene: 19472
Adprs
Name: ADP-ribosylserine hydrolase
Synonyms: Arh3, Adprhl2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100206
Homologene: 9863
Kbtbd10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Rft1
Name: RFT1 homolog
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 328370
Homologene: 5343
Zfp821
Name: zinc finger protein 821
Synonyms: 4930566A11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 75871
Homologene: 32345
Plscr2
Name: phospholipid scramblase 2
Synonyms: PL scramblase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 18828
Homologene: 134152
Ceacam5
Name: carcinoembryonic antigen-related cell adhesion molecule 5
Synonyms: 1600029H12Rik, Psg30
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 73250
Homologene: 115938
Oxnad1
Name: oxidoreductase NAD-binding domain containing 1
Synonyms: 2410002F01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 218885
Homologene: 16303
Adm
Name: adrenomedullin
Synonyms: AM
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 11535
HGNC: HGNC:259
Homologene: 873
AC154271.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Zfp865
Name: zinc finger protein 865
Synonyms: 6430526N21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 319748
Homologene: 19652
Pde6d
Name: phosphodiesterase 6D, cGMP-specific, rod, delta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 18582
HGNC: HGNC:8788
Homologene: 1954
Gm4775
Name: predicted gene 4775
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 212084
VEGA: 14
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 53,427,860 bp
  • A to G, chromosome 1 at 86,545,801 bp
  • A to T, chromosome 2 at 69,683,483 bp
  • T to C, chromosome 2 at 113,030,243 bp
  • A to G, chromosome 2 at 137,100,081 bp
  • A to G, chromosome 3 at 94,699,556 bp
  • T to C, chromosome 4 at 34,811,218 bp
  • C to T, chromosome 4 at 126,316,617 bp
  • A to G, chromosome 5 at 37,459,596 bp
  • A to G, chromosome 6 at 125,313,375 bp
  • A to G, chromosome 7 at 5,031,343 bp
  • A to T, chromosome 7 at 11,930,735 bp
  • A to C, chromosome 7 at 17,757,702 bp
  • A to G, chromosome 7 at 25,338,471 bp
  • A to T, chromosome 7 at 104,769,647 bp
  • G to T, chromosome 7 at 104,769,648 bp
  • A to G, chromosome 7 at 110,628,352 bp
  • G to T, chromosome 7 at 120,135,534 bp
  • T to G, chromosome 8 at 54,661,481 bp
  • T to C, chromosome 8 at 109,721,842 bp
  • T to C, chromosome 9 at 27,333,742 bp
  • T to C, chromosome 9 at 58,135,204 bp
  • T to A, chromosome 9 at 63,617,610 bp
  • T to C, chromosome 9 at 92,287,793 bp
  • T to C, chromosome 9 at 108,976,091 bp
  • G to A, chromosome 10 at 88,571,516 bp
  • A to G, chromosome 10 at 128,121,304 bp
  • A to G, chromosome 11 at 29,850,816 bp
  • A to G, chromosome 11 at 70,395,297 bp
  • C to T, chromosome 11 at 118,056,835 bp
  • G to T, chromosome 12 at 52,880,799 bp
  • A to G, chromosome 13 at 85,127,207 bp
  • T to C, chromosome 14 at 30,682,748 bp
  • T to A, chromosome 14 at 32,099,596 bp
  • T to C, chromosome 14 at 106,100,793 bp
  • A to G, chromosome 15 at 4,763,336 bp
  • T to C, chromosome 15 at 54,877,930 bp
  • A to G, chromosome 16 at 16,477,449 bp
  • T to C, chromosome 17 at 19,694,192 bp
  • A to T, chromosome 17 at 34,113,446 bp
  • T to C, chromosome 19 at 4,986,916 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0879 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039046-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.