Strain Name:
C57BL/6J-MtgxR1568Btlr/Mmmh
Stock Number:
039607-MU
Citation ID:
RRID:MMRRC_039607-MU
Other Names:
R1568 (G1), C57BL/6J-MtgxR1568Btlr
Major Collection:

Gene Information

Bdnf
Name: brain derived neurotrophic factor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 12064
HGNC: HGNC:1033
Homologene: 7245
Slc6a1
Name: solute carrier family 6 (neurotransmitter transporter, GABA), member 1
Synonyms: XT-1, Gabt, GAT-1, Gabt1, Gat1, Xtrp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 232333
Homologene: 2290
Nfia
Name: nuclear factor I/A
Synonyms: NF1-A, 9430022M17Rik, 1110047K16Rik, NF1A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 18027
HGNC: HGNC:7784
Homologene: 4086
Secisbp2
Name: SECIS binding protein 2
Synonyms: 2210413N07Rik, 2810012K13Rik, SBP2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 75420
Homologene: 11415
Nfya
Name: nuclear transcription factor-Y alpha
Synonyms: Sez10, Cbf-b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 18044
HGNC: HGNC:7804
Homologene: 32114
Virma
Name: vir like m6A methyltransferase associated
Synonyms: 1110037F02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 66185
Homologene: 41043
Proser1
Name: proline and serine rich 1
Synonyms: 2810046L04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 212127
Homologene: 13463
Sf3b1
Name: splicing factor 3b, subunit 1
Synonyms: SF3b155, 2810001M05Rik, Prp10, Targ4, SAP155
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 81898
Homologene: 6696
Fasn
Name: fatty acid synthase
Synonyms: A630082H08Rik, FAS
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 14104
HGNC: HGNC:3594
Homologene: 55800
Osr1
Name: odd-skipped related transcription factor 1
Synonyms: Odd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 23967
VEGA: 12
HGNC: HGNC:8111
Homologene: 8035
Myh14
Name: myosin, heavy polypeptide 14
Synonyms: 2400004E04Rik, NMHC II-C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 71960
Homologene: 23480
Clca2
Name: chloride channel accessory 2
Synonyms: Clca5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229933
HGNC: HGNC:2016
Homologene: 4765
Dsp
Name: desmoplakin
Synonyms: 5730453H04Rik, DP, 2300002E22Rik, rul
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 109620
HGNC: HGNC:3052
Homologene: 37922
Adam18
Name: a disintegrin and metallopeptidase domain 18
Synonyms: Adam27, Dtgn3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 13524
HGNC: HGNC:196
Homologene: 74941
Clca4a
Name: chloride channel accessory 4A
Synonyms: Clca6, 9130020L07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 99663
HGNC: HGNC:2018
Homologene: 40808
Ppp3ca
Name: protein phosphatase 3, catalytic subunit, alpha isoform
Synonyms: Calna, CN, 2900074D19Rik, Caln, PP2BA alpha, PP2B alpha 1, CnA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 19055
HGNC: HGNC:9314
Homologene: 55497
Dync2h1
Name: dynein cytoplasmic 2 heavy chain 1
Synonyms: 4432416O06Rik, DHC2, b2b414Clo, Dnchc2, m407Asp, m152Asp, D030010H02Rik, D330044F14Rik, DHC1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 110350
HGNC: HGNC:2962
Homologene: 14468
Cenpe
Name: centromere protein E
Synonyms: CENP-E, 312kDa, Kif10, N-7 kinesin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229841
HGNC: HGNC:1856
Homologene: 20429
Magi3
Name: membrane associated guanylate kinase, WW and PDZ domain containing 3
Synonyms: 4732496O19Rik, 6530407C02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 99470
Homologene: 26431
Cblb
Name: Casitas B-lineage lymphoma b
Synonyms: Cbl-b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 208650
VEGA: 16
HGNC: HGNC:1542
Homologene: 15856
Dna2
Name: DNA replication helicase/nuclease 2
Synonyms: Dna2l, E130315B21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 327762
HGNC: HGNC:2939
Homologene: 6124
Sec22a
Name: SEC22 homolog A, vesicle trafficking protein
Synonyms: Sec22l2, 1810005C06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 317717
Homologene: 8246
Pde4b
Name: phosphodiesterase 4B, cAMP specific
Synonyms: Dpde4, dunce
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 18578
HGNC: HGNC:8781
Homologene: 1953
Dnah5
Name: dynein, axonemal, heavy chain 5
Synonyms: b2b1537Clo, b2b1565Clo, b2b3491Clo, b2b1154Clo, Mdnah5, Dnahc5, b2b1134Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 110082
HGNC: HGNC:2950
Homologene: 1048
Pkhd1l1
Name: polycystic kidney and hepatic disease 1-like 1
Synonyms: PKHDL1, fibrocystin L, D86 mRNA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 192190
Homologene: 16332
Clspn
Name: claspin
Synonyms: E130314M08Rik, C85083
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 269582
Homologene: 11138
Cacna1d
Name: calcium channel, voltage-dependent, L type, alpha 1D subunit
Synonyms: C79217, Cav1.3alpha1, 8430418G19Rik, Cchl1a2, Cacnl1a2, D-LTCC, Cchl1a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 12289
VEGA: 14
HGNC: HGNC:1391
Homologene: 578
Sybu
Name: syntabulin (syntaxin-interacting)
Synonyms: A830027B17Rik, Golsyn/Syntabulin, 5730410E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 319613
VEGA: 15
Homologene: 9838
Cpne8
Name: copine VIII
Synonyms: 1200003E11Rik, 1500031E20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 66871
Homologene: 12049
4931408C20Rik
Name: RIKEN cDNA 4931408C20 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 210940
Homologene: 86827
Lrguk
Name: leucine-rich repeats and guanylate kinase domain containing
Synonyms: 4921528H16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 74354
Homologene: 34923
Insr
Name: insulin receptor
Synonyms: IR, IR-B, D630014A15Rik, 4932439J01Rik, CD220, IR-A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 16337
HGNC: HGNC:6091
Homologene: 20090
Arhgef38
Name: Rho guanine nucleotide exchange factor (GEF) 38
Synonyms: 9130221D24Rik, D630013G24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 77669
Homologene: 137396
Ahnak
Name: AHNAK nucleoprotein (desmoyokin)
Synonyms: 1110004P15Rik, 2310047C17Rik, DY6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 66395
VEGA: 19
HGNC: HGNC:347
Homologene: 67425
Pde8a
Name: phosphodiesterase 8A
Synonyms: Pde8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 18584
HGNC: HGNC:8793
Homologene: 1957
Adgb
Name: androglobin
Synonyms: 9130014G24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 215772
Homologene: 100289
Vwde
Name: von Willebrand factor D and EGF domains
Synonyms: LOC232585
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 232585
Homologene: 35456
Zyg11a
Name: zyg-11 family member A, cell cycle regulator
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230590
Homologene: 66294
Olfr1308
Name: olfactory receptor 1308
Synonyms: GA_x6K02T2Q125-73008844-73007882, MOR245-22
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258258
Homologene: 45797
Krt76
Name: keratin 76
Synonyms: 2310001L23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 77055
Homologene: 22931
Prl8a9
Name: prolactin family8, subfamily a, member 9
Synonyms: PLP-Cbeta, 1600019F10Rik, Prlpc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 67310
Homologene: 11344
0610010F05Rik
Name: RIKEN cDNA 0610010F05 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 71675
Homologene: 19038
Olfr1410
Name: olfactory receptor 1410
Synonyms: GA_x6K02T2R7CC-81146179-81145211, MOR208-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 258484
Homologene: 74205
Adamdec1
Name: ADAM-like, decysin 1
Synonyms: 2210414L24Rik, Dcsn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 58860
VEGA: 14
Homologene: 8711
Slc39a10
Name: solute carrier family 39 (zinc transporter), member 10
Synonyms: 2900042E17Rik, Zip10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 227059
Homologene: 34076
Lgmn
Name: legumain
Synonyms: preprolegumain, AEP, Prsc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 19141
HGNC: HGNC:9472
Homologene: 38075
Adra1d
Name: adrenergic receptor, alpha 1d
Synonyms: Adra-1, Adra1, alpha1D-AR, Gpcr8, Adra1a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 11550
HGNC: HGNC:280
Homologene: 551
Olfr658
Name: olfactory receptor 658
Synonyms: GA_x6K02T2PBJ9-7273558-7272587, MOR34-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 259051
Homologene: 105161
Aars2
Name: alanyl-tRNA synthetase 2, mitochondrial
Synonyms: Aarsl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 224805
VEGA: 17
Homologene: 56897
Spag6l
Name: sperm associated antigen 6-like
Synonyms: PF16, Spag6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 50525
Homologene: 8252
Lamp3
Name: lysosomal-associated membrane protein 3
Synonyms: DC-LAMP, 1200002D17Rik, Cd208, TSC403
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 239739
VEGA: 16
Homologene: 8670
Icosl
Name: icos ligand
Synonyms: B7h, GL50-B, B7-H2, ICOS-L, B7RP-1, LICOS, GL50
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 50723
VEGA: 10
Homologene: 49412
Serpinb6b
Name: serine (or cysteine) peptidase inhibitor, clade B, member 6b
Synonyms: ovalbumin, NK13, Spi12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 20708
HGNC: HGNC:8950
Homologene: 22633
Ankmy1
Name: ankyrin repeat and MYND domain containing 1
Synonyms: 4930483I10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 241158
Homologene: 9561
Atp8b4
Name: ATPase, class I, type 8B, member 4
Synonyms: Im
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241633
Homologene: 133162
Lpgat1
Name: lysophosphatidylglycerol acyltransferase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226856
Homologene: 8914
D6Ertd527e
Name: DNA segment, Chr 6, ERATO Doi 527, expressed
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 52372
Vmn2r86
Name: vomeronasal 2, receptor 86
Synonyms: EG625109
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 625109
Homologene: 129606
Cd163
Name: CD163 antigen
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 93671
HGNC: HGNC:1631
Homologene: 128811
Atp8b2
Name: ATPase, class I, type 8B, member 2
Synonyms: Id
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 54667
Homologene: 23226
Rgs20
Name: regulator of G-protein signaling 20
Synonyms: 2900073E09Rik, Rgsz1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 58175
Homologene: 2745
Zfp873
Name: zinc finger protein 873
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 408062
Homologene: 134319
Vmn1r229
Name: vomeronasal 1 receptor 229
Synonyms: V1re1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 171224
Homologene: 74319
Npffr1
Name: neuropeptide FF receptor 1
Synonyms: NPFF1R, LOC237362, NPFF1, Gpr147
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 237362
Homologene: 23348
Olfr1466
Name: olfactory receptor 1466
Synonyms: MOR202-12, GA_x6K02T2RE5P-3672907-3673839
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 258689
Homologene: 133677
Vmn1r238
Name: vomeronasal 1 receptor, 238
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 100312476
Homologene: 128342
Ghdc
Name: GH3 domain containing
Synonyms: D11Lgp1e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 80860
Homologene: 32760
Wfdc13
Name: WAP four-disulfide core domain 13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 408190
Homologene: 134107
Klrc3
Name: killer cell lectin-like receptor subfamily C, member 3
Synonyms: NKG2E
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 58179
HGNC: HGNC:6376
Homologene: 130643
Gins2
Name: GINS complex subunit 2 (Psf2 homolog)
Synonyms: 4833427B12Rik, 2210013I18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 272551
Homologene: 41105
Spag6
Name: sperm associated antigen 6
Synonyms: BC061194, Spag6l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 381350
Homologene: 133723
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to T, chromosome 1 at 5,020,827 bp
  • T to C, chromosome 1 at 26,685,869 bp
  • A to T, chromosome 1 at 46,826,215 bp
  • C to G, chromosome 1 at 55,019,395 bp
  • T to C, chromosome 1 at 92,607,954 bp
  • T to C, chromosome 1 at 92,881,116 bp
  • A to T, chromosome 1 at 191,776,426 bp
  • A to G, chromosome 2 at 18,733,114 bp
  • A to G, chromosome 2 at 109,723,794 bp
  • C to A, chromosome 2 at 111,960,240 bp
  • G to T, chromosome 2 at 126,325,394 bp
  • T to C, chromosome 2 at 131,546,172 bp
  • G to T, chromosome 2 at 164,686,934 bp
  • T to C, chromosome 3 at 53,477,759 bp
  • T to C, chromosome 3 at 89,949,848 bp
  • A to C, chromosome 3 at 104,089,527 bp
  • C to T, chromosome 3 at 133,132,464 bp
  • T to A, chromosome 3 at 135,239,758 bp
  • A to G, chromosome 3 at 136,928,544 bp
  • A to G, chromosome 3 at 144,952,929 bp
  • A to T, chromosome 3 at 145,075,649 bp
  • T to C, chromosome 4 at 11,528,776 bp
  • T to G, chromosome 4 at 98,111,224 bp
  • A to C, chromosome 4 at 102,597,699 bp
  • A to G, chromosome 4 at 108,183,646 bp
  • T to A, chromosome 4 at 126,581,517 bp
  • G to T, chromosome 6 at 13,187,800 bp
  • T to A, chromosome 6 at 34,086,438 bp
  • C to G, chromosome 6 at 87,111,524 bp
  • G to T, chromosome 6 at 114,307,770 bp
  • T to A, chromosome 6 at 124,326,154 bp
  • T to C, chromosome 6 at 129,639,547 bp
  • G to A, chromosome 7 at 44,611,698 bp
  • A to G, chromosome 7 at 81,292,263 bp
  • T to A, chromosome 7 at 104,644,770 bp
  • A to T, chromosome 8 at 3,165,576 bp
  • T to G, chromosome 8 at 24,647,783 bp
  • T to C, chromosome 8 at 120,582,200 bp
  • T to C, chromosome 9 at 7,157,553 bp
  • A to T, chromosome 10 at 10,442,665 bp
  • T to A, chromosome 10 at 61,626,233 bp
  • C to T, chromosome 10 at 62,949,187 bp
  • T to C, chromosome 10 at 78,077,882 bp
  • C to A, chromosome 10 at 82,060,279 bp
  • C to T, chromosome 10 at 130,453,141 bp
  • T to C, chromosome 11 at 23,589,971 bp
  • A to G, chromosome 11 at 100,768,505 bp
  • A to T, chromosome 11 at 120,813,249 bp
  • G to A, chromosome 12 at 9,579,798 bp
  • T to C, chromosome 12 at 102,394,609 bp
  • A to T, chromosome 13 at 27,561,542 bp
  • T to C, chromosome 13 at 32,974,912 bp
  • T to C, chromosome 13 at 38,175,147 bp
  • A to G, chromosome 13 at 51,673,107 bp
  • G to T, chromosome 14 at 30,075,267 bp
  • T to A, chromosome 14 at 68,570,883 bp
  • T to A, chromosome 15 at 28,409,177 bp
  • A to T, chromosome 15 at 44,545,501 bp
  • G to T, chromosome 15 at 44,718,832 bp
  • G to T, chromosome 15 at 90,619,642 bp
  • T to A, chromosome 15 at 101,885,008 bp
  • A to T, chromosome 16 at 19,673,525 bp
  • T to C, chromosome 16 at 35,347,628 bp
  • C to T, chromosome 16 at 52,135,829 bp
  • T to A, chromosome 17 at 20,814,805 bp
  • G to T, chromosome 17 at 45,516,088 bp
  • A to C, chromosome 17 at 48,391,234 bp
  • T to C, chromosome 18 at 3,123,358 bp
  • G to A, chromosome 19 at 9,002,375 bp
  • C to A, chromosome 19 at 13,342,175 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1568 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039607-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.