Strain Name:
C57BL/6J-MtgxR1743Btlr/Mmmh
Stock Number:
039775-MU
Citation ID:
RRID:MMRRC_039775-MU
Other Names:
R1743 (G1), C57BL/6J-MtgxR1743Btlr
Major Collection:

Strain Information

St8sia1
Name: ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
Synonyms: Siat8a, GD3 synthase, GD3S, alpha-2,8-sialyltransferase, Siat8, 9330109E03Rik, ST8Sia I
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 20449
Homologene: 2282
Ank2
Name: ankyrin 2, brain
Synonyms: Ankyrin-2, Ank-2, Gm4392, Ankyrin-B, ankyrin B
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 109676
HGNC: HGNC:493
Cbx7
Name: chromobox 7
Synonyms: 1600014J01Rik, D15Ertd417e
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 52609
HGNC: HGNC:1557
Homologene: 65296
Cnst
Name: consortin, connexin sorting protein
Synonyms: 9630058J23Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226744
Homologene: 17139
Ap2b1
Name: adaptor-related protein complex 2, beta 1 subunit
Synonyms: 1300012O03Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 71770
HGNC: HGNC:563
Homologene: 137384
Wdfy3
Name: WD repeat and FYVE domain containing 3
Synonyms: 2610509D04Rik, Ggtb3, Bchs, D5Ertd66e, Bwf1, Alfy
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 72145
Homologene: 22855
Lrsam1
Name: leucine rich repeat and sterile alpha motif containing 1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227738
Homologene: 44526
Polr2a
Name: polymerase (RNA) II (DNA directed) polypeptide A
Synonyms: 220kDa, Rpo2-1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 20020
HGNC: HGNC:9187
Homologene: 721
Rapgef6
Name: Rap guanine nucleotide exchange factor (GEF) 6
Synonyms: C030018K18Rik, PDZ-GEF2, RA-GEF-2, Pdzgef2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 192786
Homologene: 22968
Bcl2l13
Name: BCL2 like 13
Synonyms: Mil1, BCL-RAMBO, Mil-1, E430016C20Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 94044
Homologene: 9111
Birc6
Name: baculoviral IAP repeat-containing 6
Synonyms: Bruce, D630005A10Rik, A430040A19Rik, apollon, A430032G04Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 12211
Homologene: 7248
Zc3h14
Name: zinc finger CCCH type containing 14
Synonyms: 1700016A15Rik, 2700069A02Rik, 1010001P15Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 75553
VEGA: 12
Homologene: 32605
Nomo1
Name: nodal modulator 1
Synonyms: PM5, D7Ertd156e, Nomo
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 211548
Homologene: 13810
Tacc2
Name: transforming, acidic coiled-coil containing protein 2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 57752
Homologene: 5087
Fndc3a
Name: fibronectin type III domain containing 3A
Synonyms: F730017H24Rik, 1700094E19Rik, D14Ertd453e, sys, Fndc3
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 319448
Homologene: 8952
Arhgap32
Name: Rho GTPase activating protein 32
Synonyms: PX-RICS, GC-GAP, p200RhoGAP, Grit, 3426406O18Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 330914
Homologene: 8812
Bub1
Name: BUB1, mitotic checkpoint serine/threonine kinase
Synonyms: Bub1a, D2Xrf87
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12235
HGNC: HGNC:1148
Homologene: 37910
Cenpf
Name: centromere protein F
Synonyms: 6530404A22Rik, Lek1, mitosin
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 108000
HGNC: HGNC:1857
Homologene: 22969
Aff4
Name: AF4/FMR2 family, member 4
Synonyms: Laf4l, Alf4
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 93736
Homologene: 8683
Sec23b
Name: SEC23 homolog B, COPII coat complex component
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 27054
Homologene: 74571
Rims2
Name: regulating synaptic membrane exocytosis 2
Synonyms: 2810036I15Rik, Syt3-rs, RIM2
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 116838
VEGA: 15
Homologene: 81639
Ccdc15
Name: coiled-coil domain containing 15
Synonyms: A630039F14Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 245902
VEGA: 9
Homologene: 28448
Taf1b
Name: TATA-box binding protein associated factor, RNA polymerase I, B
Synonyms: p63, A230108M10Rik, mTAFI68, 4930408G01Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 21340
VEGA: 12
Homologene: 31331
Mcm3ap
Name: minichromosome maintenance complex component 3 associated protein
Synonyms: GANP
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 54387
VEGA: 10
HGNC: HGNC:6946
Homologene: 2902
Dnah7a
Name: dynein, axonemal, heavy chain 7A
Synonyms: LOC381341, Dnahc7, Dnahc7a
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 627872
Homologene: 41287
Akt2
Name: thymoma viral proto-oncogene 2
Synonyms: PKBbeta, 2410016A19Rik, PKB
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 11652
HGNC: HGNC:392
Homologene: 48773
Ppil4
Name: peptidylprolyl isomerase (cyclophilin)-like 4
Synonyms: PPIase, 3732410E19Rik, 3830425H19Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 67418
Homologene: 12126
Ncam1
Name: neural cell adhesion molecule 1
Synonyms: NCAM, NCAM-120, NCAM-1, CD56, E-NCAM, NCAM-180, NCAM-140
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 17967
HGNC: HGNC:7656
Homologene: 40754
Fbf1
Name: Fas binding factor 1
Synonyms: 1110033G01Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217335
Homologene: 16531
Dnah8
Name: dynein, axonemal, heavy chain 8
Synonyms: P1-Loop, Hst6.7b, Dnahc8
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 13417
VEGA: 17
HGNC: HGNC:2952
Homologene: 1049
Ext2
Name: exostosin glycosyltransferase 2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14043
HGNC: HGNC:3513
Homologene: 345
Nipsnap2
Name: nipsnap homolog 2
Synonyms: Gbas, Nipsnap2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 14467
HGNC: HGNC:4179
Homologene: 1137
Epn2
Name: epsin 2
Synonyms: 9530051D10Rik, Ibp2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 13855
Homologene: 40710
Cul2
Name: cullin 2
Synonyms: 1300003D18Rik, 4932411N15Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 71745
HGNC: HGNC:2552
Homologene: 2662
Tsc22d2
Name: TSC22 domain family, member 2
Synonyms: 1810043J12Rik, 5530402M19Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 72033
Homologene: 8860
Timm21
Name: translocase of inner mitochondrial membrane 21
Synonyms: 2700002I20Rik, 1700034H14Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 67105
VEGA: 18
Homologene: 32211
Ranbp10
Name: RAN binding protein 10
Synonyms: 4432417N03Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 74334
Homologene: 49639
Ssh2
Name: slingshot protein phosphatase 2
Synonyms: SSH-2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237860
Homologene: 14116
Cep295
Name: centrosomal protein 295
Synonyms: LOC382128, 5830418K08Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 319675
Homologene: 27936
Nacc2
Name: nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
Synonyms: Btbd14a, 0610020I02Rik, C030048H19Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 67991
Homologene: 75239
Ghr
Name: growth hormone receptor
Synonyms: GHR/BP, GHBP
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 14600
HGNC: HGNC:4263
Homologene: 134
Nos3
Name: nitric oxide synthase 3, endothelial cell
Synonyms: ecNOS, 2310065A03Rik, Nos-3, eNOS
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 18127
HGNC: HGNC:7876
Homologene: 504
Klb
Name: klotho beta
Synonyms: betaKlotho
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 83379
Homologene: 12820
Cmya5
Name: cardiomyopathy associated 5
Synonyms: Myospryn, 2310076E21Rik, 2310076E16Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 76469
VEGA: 13
Homologene: 137367
Dnai3
Name: dynein axonemal intermediate chain 3
Synonyms: 4931433A13Rik, IC140, Ida7, Wdr63
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 242253
Homologene: 44922
Hephl1
Name: hephaestin-like 1
Synonyms: zyklopen, LOC244698, thd, cw, Zp
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 244698
Homologene: 9112
Loxl2
Name: lysyl oxidase-like 2
Synonyms: 9430067E15Rik, 1110004B06Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 94352
HGNC: HGNC:6666
Homologene: 1742
Nlrp1a
Name: NLR family, pyrin domain containing 1A
Synonyms: Nalp1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 195046
Homologene: 133820
Atp7b
Name: ATPase, Cu++ transporting, beta polypeptide
Synonyms: WND, Atp7a, Wilson protein
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 11979
HGNC: HGNC:870
Homologene: 20063
Csmd3
Name: CUB and Sushi multiple domains 3
Synonyms: 4930500N14Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 239420
Homologene: 65982
Slc16a7
Name: solute carrier family 16 (monocarboxylic acid transporters), member 7
Synonyms: D630004K10Rik, MCT2, 9030411M13Rik, 4921534N07Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 20503
Homologene: 20990
Slc25a30
Name: solute carrier family 25, member 30
Synonyms: KMCP1, 4933433D23Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 67554
VEGA: 14
Homologene: 57046
Pstpip1
Name: proline-serine-threonine phosphatase-interacting protein 1
Synonyms: def-2, CD2BP1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 19200
HGNC: HGNC:9580
Homologene: 37867
Or10n1
Name: olfactory receptor family 10 subfamily N member 1
Synonyms: GA_x6K02T2PVTD-33310486-33311418, M30, Olfr148, MOR224-4
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258498
VEGA: 9
Homologene: 128136
Pcdhb14
Name: protocadherin beta 14
Synonyms: Pcdhb17, PcdhbN, 2210006M07Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93885
Homologene: 70876
Lrrc9
Name: leucine rich repeat containing 9
Synonyms: 4921529O18Rik, 4930432K16Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 78257
Homologene: 12692
Gabbr2
Name: gamma-aminobutyric acid type B receptor subunit 2
Synonyms: LOC242425, Gababr2, Gpr51, GB2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242425
HGNC: HGNC:4507
Homologene: 55902
Tssk4
Name: testis-specific serine kinase 4
Synonyms: 4933424F08Rik, 1700020B19Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 71099
VEGA: 14
Homologene: 57078
Hnf4a
Name: hepatic nuclear factor 4, alpha
Synonyms: HNF-4, Nuclear receptor 2A1, MODY1, HNF4 alpha, Tcf14, Tcf4, Nr2a1, Hnf4
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 15378
HGNC: HGNC:5024
Homologene: 395
Qrsl1
Name: glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1
Synonyms: 2700038P16Rik, GatA
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 76563
Homologene: 6699
Sh3tc1
Name: SH3 domain and tetratricopeptide repeats 1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231147
Homologene: 10360
Usp9y
Name: ubiquitin specific peptidase 9, Y chromosome
Synonyms: Dffry, Fafl2
Type: Gene
Species: Mouse
Chromosome: Y
NCBI: 107868
Homologene: 68408
Sphkap
Name: SPHK1 interactor, AKAP domain containing
Synonyms: SKIP, 4930544G21Rik, A930009L15Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 77629
Homologene: 18172
Zfp821
Name: zinc finger protein 821
Synonyms: 4930566A11Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 75871
Homologene: 32345
Cnnm1
Name: cyclin M1
Synonyms: Acdp1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 83674
VEGA: 19
HGNC: HGNC:102
Homologene: 10673
Gm7275
Name: predicted gene 7275
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 639644
VEGA: 16
Coa8
Name: cytochrome c oxidase assembly factor 8
Synonyms: Apopt1, 2810002N01Rik, Apop-1, 1700081D05Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 68020
Homologene: 12225
Prkd1
Name: protein kinase D1
Synonyms: Prkcm, PKD1, Pkcm
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 18760
VEGA: 12
HGNC: HGNC:9407
Homologene: 55680
Nfkbiz
Name: nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta
Synonyms: Mail
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 80859
Homologene: 12734
Repin1
Name: replication initiator 1
Synonyms: Zfp464, AP4, E430037F08Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 58887
Homologene: 22810
Or10ak16
Name: olfactory receptor family 10 subfamily AK member 16
Synonyms: GA_x6K02T2QD9B-18644371-18643424, MOR259-8, Olfr1330
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 258331
Homologene: 121524
Glipr1l2
Name: GLI pathogenesis-related 1 like 2
Synonyms: 4921508O11Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 67537
Homologene: 17579
Sdc2
Name: syndecan 2
Synonyms: Hspg1, fibroglycan, 4833414L08Rik, Synd2
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 15529
Homologene: 2253
Kcne3
Name: potassium voltage-gated channel, Isk-related subfamily, gene 3
Synonyms: 2210017H05Rik, MiRP2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 57442
HGNC: HGNC:6243
Homologene: 3994
Gm10608
Name: predicted gene 10608
Synonyms: EG546165
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 546165
VEGA: 9
Coq8a
Name: coenzyme Q8A
Synonyms: 4632432J16Rik, Cabc1, Adck3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 67426
Homologene: 11345
Rnaset2b
Name: ribonuclease T2B
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 68195
VEGA: 17
Homologene: 31190
Or2b2
Name: olfactory receptor family 2 subfamily B member 2
Synonyms: GA_x6K02T2QHY8-11534186-11533245, Olfr1359, MOR256-35, MOR256-60
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 258067
Homologene: 11056
Oxct2a
Name: 3-oxoacid CoA transferase 2A
Synonyms: Scot-t1, Oxct2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 64059
Homologene: 137359
Tmem165
Name: transmembrane protein 165
Synonyms: Tparl, pFT27, Tpardl
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 21982
Homologene: 5411
Vmn2r42
Name: vomeronasal 2, receptor 42
Synonyms: V2r4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 22310
Homologene: 113703
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 53,427,814 bp
  • G to A, chromosome 1 at 83,277,515 bp
  • C to T, chromosome 1 at 179,610,392 bp
  • T to C, chromosome 1 at 180,182,229 bp
  • T to C, chromosome 1 at 189,654,263 bp
  • T to C, chromosome 2 at 26,060,143 bp
  • A to G, chromosome 2 at 32,941,883 bp
  • T to C, chromosome 2 at 93,730,225 bp
  • T to C, chromosome 2 at 127,813,850 bp
  • T to C, chromosome 2 at 144,587,489 bp
  • C to A, chromosome 2 at 163,566,339 bp
  • TCAGTTAACACCTATGAACAGT to TCAGT, chromosome 3 at 58,417,539 bp
  • T to C, chromosome 3 at 126,928,675 bp
  • C to A, chromosome 3 at 146,097,262 bp
  • A to G, chromosome 4 at 46,677,603 bp
  • A to G, chromosome 4 at 118,893,526 bp
  • A to T, chromosome 4 at 123,323,516 bp
  • T to C, chromosome 4 at 144,333,005 bp
  • G to A, chromosome 5 at 24,377,312 bp
  • A to G, chromosome 5 at 35,714,057 bp
  • C to A, chromosome 5 at 65,375,861 bp
  • G to T, chromosome 5 at 76,207,826 bp
  • G to T, chromosome 5 at 101,844,065 bp
  • T to C, chromosome 5 at 129,757,085 bp
  • T to A, chromosome 6 at 48,597,750 bp
  • T to A, chromosome 6 at 120,848,543 bp
  • A to T, chromosome 6 at 142,829,016 bp
  • A to T, chromosome 7 at 8,184,265 bp
  • A to G, chromosome 7 at 27,637,208 bp
  • G to T, chromosome 7 at 41,546,452 bp
  • G to A, chromosome 7 at 46,070,037 bp
  • C to T, chromosome 7 at 100,184,424 bp
  • C to A, chromosome 7 at 130,626,598 bp
  • A to T, chromosome 8 at 22,006,387 bp
  • G to T, chromosome 8 at 105,779,978 bp
  • G to A, chromosome 8 at 109,724,164 bp
  • C to T, chromosome 9 at 15,090,068 bp
  • C to T, chromosome 9 at 15,340,883 bp
  • A to G, chromosome 9 at 32,259,431 bp
  • A to T, chromosome 9 at 37,277,477 bp
  • A to T, chromosome 9 at 39,613,620 bp
  • G to T, chromosome 9 at 49,557,145 bp
  • T to C, chromosome 9 at 56,125,930 bp
  • CAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGA to CAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGA, chromosome 9 at 119,160,716 bp
  • A to G, chromosome 10 at 6,830,105 bp
  • A to T, chromosome 10 at 7,807,381 bp
  • A to T, chromosome 10 at 43,881,515 bp
  • C to T, chromosome 10 at 76,484,674 bp
  • G to T, chromosome 10 at 112,092,565 bp
  • A to G, chromosome 10 at 125,294,581 bp
  • T to A, chromosome 11 at 53,368,695 bp
  • A to G, chromosome 11 at 54,676,284 bp
  • T to A, chromosome 11 at 61,546,411 bp
  • A to G, chromosome 11 at 69,739,503 bp
  • A to T, chromosome 11 at 71,124,206 bp
  • T to A, chromosome 11 at 77,437,756 bp
  • T to C, chromosome 11 at 83,335,617 bp
  • A to G, chromosome 11 at 116,154,067 bp
  • A to G, chromosome 12 at 24,547,178 bp
  • G to A, chromosome 12 at 50,394,685 bp
  • A to T, chromosome 12 at 72,456,117 bp
  • T to C, chromosome 12 at 98,779,189 bp
  • T to A, chromosome 12 at 102,390,096 bp
  • T to C, chromosome 12 at 111,722,823 bp
  • A to G, chromosome 13 at 21,703,450 bp
  • A to G, chromosome 13 at 93,097,317 bp
  • C to A, chromosome 14 at 55,651,031 bp
  • T to A, chromosome 14 at 69,692,402 bp
  • A to T, chromosome 14 at 72,652,081 bp
  • C to A, chromosome 14 at 75,775,083 bp
  • G to A, chromosome 15 at 3,320,241 bp
  • A to G, chromosome 15 at 33,028,078 bp
  • A to T, chromosome 15 at 39,679,650 bp
  • A to G, chromosome 15 at 48,622,089 bp
  • G to A, chromosome 15 at 79,921,447 bp
  • A to G, chromosome 16 at 48,073,757 bp
  • G to T, chromosome 16 at 55,816,394 bp
  • G to T, chromosome 17 at 6,988,801 bp
  • G to T, chromosome 17 at 30,769,651 bp
  • A to G, chromosome 17 at 74,579,756 bp
  • A to T, chromosome 18 at 3,426,851 bp
  • T to G, chromosome 18 at 37,448,178 bp
  • G to C, chromosome 18 at 84,949,262 bp
  • A to T, chromosome 19 at 43,471,913 bp
  • A to G, chromosome Y at 1,316,727 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1743 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039775-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.