Strain Name:
C57BL/6J-MtgxR1943Btlr/Mmmh
Stock Number:
039961-MU
Citation ID:
RRID:MMRRC_039961-MU
Other Names:
R1943 (G1), C57BL/6J-MtgxR1943Btlr
Major Collection:

Gene Information

Dst
Name: dystonin
Synonyms: A830042E19Rik, 2310001O04Rik, Macf2, bullous pemphigoid antigen 1, BPAG1-n, BPAG1, athetoid, Bpag, ah, bullous pemphigoid antigen 1, Bpag1, nmf339, nmf203
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 13518
HGNC: HGNC:1090
Homologene: 136716
Cemip2
Name: cell migration inducing hyaluronidase 2
Synonyms: 3110012M15Rik, Tmem2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 83921
VEGA: 19
Homologene: 75008
Rnf38
Name: ring finger protein 38
Synonyms: Oip1, 1700065B19Rik, 2610202O07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 73469
Homologene: 32550
Ptpra
Name: protein tyrosine phosphatase, receptor type, A
Synonyms: PTP[a], RPTPalpha, Ptpa, RPTRalpha, PTPalpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 19262
HGNC: HGNC:9664
Homologene: 20621
Adam23
Name: a disintegrin and metallopeptidase domain 23
Synonyms: MDC3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 23792
HGNC: HGNC:202
Homologene: 2826
Tfr2
Name: transferrin receptor 2
Synonyms: Tfr2, Trfr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 50765
Homologene: 2428
Rapgef6
Name: Rap guanine nucleotide exchange factor (GEF) 6
Synonyms: Pdzgef2, PDZ-GEF2, C030018K18Rik, RA-GEF-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 192786
Homologene: 22968
Chchd6
Name: coiled-coil-helix-coiled-coil-helix domain containing 6
Synonyms: 1700021B03Rik, Micos25, 0710001P09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 66098
Homologene: 11920
Sf3a3
Name: splicing factor 3a, subunit 3
Synonyms: 4930512K19Rik, 60kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 75062
Homologene: 4949
Prrc2a
Name: proline-rich coiled-coil 2A
Synonyms: Wbp12, 3110039B05Rik, Bat-2, D17H6S51E, Bat2, G2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 53761
Homologene: 10567
Fh1
Name: fumarate hydratase 1
Synonyms: fumarase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 14194
HGNC: HGNC:3700
Homologene: 115
Lamtor4
Name: late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
Synonyms: 0910001L09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 66096
Homologene: 19241
Ryr2
Name: ryanodine receptor 2, cardiac
Synonyms: 9330127I20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 20191
VEGA: 13
Homologene: 37423
Slc43a2
Name: solute carrier family 43, member 2
Synonyms: 7630402D21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 215113
Homologene: 17555
Bicc1
Name: BicC family RNA binding protein 1
Synonyms: jcpk, Bic-C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 83675
Homologene: 12856
Dennd1b
Name: DENN/MADD domain containing 1B
Synonyms: 4632404N19Rik, 4930467M19Rik, 6820401H01Rik, F730008N07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 329260
Homologene: 11739
Vps13d
Name: vacuolar protein sorting 13D
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230895
Homologene: 15583
Lmo7
Name: LIM domain only 7
Synonyms: FBXO20, LOC380928
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 380928
HGNC: HGNC:6646
Homologene: 83924
Acp5
Name: acid phosphatase 5, tartrate resistant
Synonyms: TRAP, TRACP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 11433
VEGA: 9
HGNC: HGNC:124
Homologene: 137203
Chst15
Name: carbohydrate sulfotransferase 15
Synonyms: 4631426J05Rik, GalNAcS-6ST, MAd5, MAd5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 77590
Homologene: 8908
Mknk1
Name: MAP kinase-interacting serine/threonine kinase 1
Synonyms: 2410048M24Rik, Mnk1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 17346
HGNC: HGNC:7110
Homologene: 37838
Tyw3
Name: tRNA-yW synthesizing protein 3 homolog (S. cerevisiae)
Synonyms: 5230400J09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 209584
Homologene: 44531
Dhtkd1
Name: dehydrogenase E1 and transketolase domain containing 1
Synonyms: C330018I04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 209692
Homologene: 10278
Tmtc1
Name: transmembrane and tetratricopeptide repeat containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 387314
Homologene: 65299
Txndc12
Name: thioredoxin domain containing 12 (endoplasmic reticulum)
Synonyms: ERp16, 0610040B21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 66073
Homologene: 41074
Myo16
Name: myosin XVI
Synonyms: BM140241, C230040D10Rik, Nyap3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 244281
Homologene: 34710
Lama4
Name: laminin, alpha 4
Synonyms: laminin [a]4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 16775
HGNC: HGNC:6484
Homologene: 37604
Xirp2
Name: xin actin-binding repeat containing 2
Synonyms: A530024P18Rik, myomaxin, Cmya3, 2310008C07Rik, mXin beta, 2310003D02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241431
Homologene: 19388
Slc45a1
Name: solute carrier family 45, member 1
Synonyms: Dnb5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 242773
Homologene: 44908
Cntnap4
Name: contactin associated protein-like 4
Synonyms: E130114F09Rik, Caspr4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 170571
Homologene: 24912
Tmem62
Name: transmembrane protein 62
Synonyms: B830009D23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 96957
Homologene: 11801
Rnf32
Name: ring finger protein 32
Synonyms: 1700009J01Rik, Lmbr2, 2700025B22Rik, 4930542N22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 56874
Homologene: 10986
A2m
Name: alpha-2-macroglobulin
Synonyms: A2mp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 232345
HGNC: HGNC:7
Homologene: 37248
Ugt8a
Name: UDP galactosyltransferase 8A
Synonyms: Cgt, mCerGT, Ugt8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 22239
Homologene: 20715
Daw1
Name: dynein assembly factor with WDR repeat domains 1
Synonyms: 4930563E19Rik, Wdr69, b2b1584Clo, b2b1116Clo, 4933429D11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 71227
Adam34
Name: a disintegrin and metallopeptidase domain 34
Synonyms: testase 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 252866
Homologene: 78104
Abca8a
Name: ATP-binding cassette, sub-family A (ABC1), member 8a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 217258
HGNC: HGNC:38
Homologene: 131160
Arsa
Name: arylsulfatase A
Synonyms: As2, ASA, AS-A, As-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 11883
HGNC: HGNC:713
Homologene: 20138
Olfr169
Name: olfactory receptor 169
Synonyms: MOR273-3P, GA_x54KRFPKG5P-16014972-16014031
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 258158
Homologene: 128058
Cacna1i
Name: calcium channel, voltage-dependent, alpha 1I subunit
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 239556
HGNC: HGNC:1396
Homologene: 69331
Vmn2r93
Name: vomeronasal 2, receptor 93
Synonyms: EG627132
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 627132
Homologene: 129750
Snx15
Name: sorting nexin 15
Synonyms: 1500032B08Rik, E130013C21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 69024
Homologene: 12294
Ciao3
Name: cytosolic iron-sulfur assembly component 3
Synonyms: Narfl, 9030612I22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 67563
Homologene: 6750
Spef2
Name: sperm flagellar 2
Synonyms: C230086A09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 320277
Homologene: 23371
Adgrg3
Name: adhesion G protein-coupled receptor G3
Synonyms: A030001G24Rik, Gpr97, Pb99
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 54672
Homologene: 18129
Mug2
Name: murinoglobulin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 17837
Homologene: 136663
Zfp661
Name: zinc finger protein 661
Synonyms: 2810405K07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 72180
Homologene: 23275
Phtf1
Name: putative homeodomain transcription factor 1
Synonyms: Phft
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 18685
HGNC: HGNC:8939
Homologene: 4817
Shisa9
Name: shisa family member 9
Synonyms: CKAMP44, 2700045P11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 72555
Homologene: 109462
Osbpl3
Name: oxysterol binding protein-like 3
Synonyms: 1200014M06Rik, 6720421I08Rik, ORP3, OSBP3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 71720
Homologene: 49422
Luzp2
Name: leucine zipper protein 2
Synonyms: 9330154K17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233271
Homologene: 45618
Llgl1
Name: LLGL1 scribble cell polarity complex component
Synonyms: Lgl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 16897
HGNC: HGNC:6628
Homologene: 31220
Parp14
Name: poly (ADP-ribose) polymerase family, member 14
Synonyms: CoaSt6, collaborator of Stat6, 1600029O10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 547253
Homologene: 19697
Vmn2r96
Name: vomeronasal 2, receptor 96
Synonyms: EG433070
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 433070
Ercc3
Name: excision repair cross-complementing rodent repair deficiency, complementation group 3
Synonyms: XPB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 13872
HGNC: HGNC:3435
Homologene: 96
Cpz
Name: carboxypeptidase Z
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 242939
HGNC: HGNC:2333
Homologene: 2709
Olfr51
Name: olfactory receptor 51
Synonyms: MOR129-3, ID7, GA_x6K02T2QP88-4431129-4430206
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 18351
Homologene: 133578
Zfp715
Name: zinc finger protein 715
Synonyms: mszf15, 2610041B18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 69930
Homologene: 74591
Rsph6a
Name: radial spoke head 6 homolog A (Chlamydomonas)
Synonyms: Rshl1, RSP4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 83434
Homologene: 36476
Pmp2
Name: peripheral myelin protein 2
Synonyms: P2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 18857
HGNC: HGNC:9117
Homologene: 20589
Zfp512b
Name: zinc finger protein 512B
Synonyms: LOC269401, Znf512b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 269401
Homologene: 69314
Tigit
Name: T cell immunoreceptor with Ig and ITIM domains
Synonyms: Vstm3, ENSMUSG00000071552
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 100043314
VEGA: 16
Homologene: 18358
Dmgdh
Name: dimethylglycine dehydrogenase precursor
Synonyms: 1200014D15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 74129
Homologene: 8372
Slc7a10
Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 10
Synonyms: D7Bwg0847e, Asc-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 53896
Homologene: 56767
Tedc2
Name: tubulin epsilon and delta complex 2
Synonyms: 1600002H07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 72016
Homologene: 45943
Il1rn
Name: interleukin 1 receptor antagonist
Synonyms: F630041P17Rik, IL-1ra
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 16181
HGNC: HGNC:6000
Homologene: 11163
AC132362.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
Coro2a
Name: coronin, actin binding protein 2A
Synonyms: coronin 4, 9030208C03Rik, IR10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 107684
HGNC: HGNC:2255
Homologene: 2546
Zfp606
Name: zinc finger protein 606
Synonyms: 2410022M24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 67370
Homologene: 23514
Gm13199
Name: predicted gene 13199
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 791411
9130204L05Rik
Name: RIKEN cDNA 9130204L05 gene
Synonyms: LOC229550
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229550
Homologene: 135857
Rdh14
Name: retinol dehydrogenase 14 (all-trans and 9-cis)
Synonyms: 3110030G19Rik, PAN2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 105014
VEGA: 12
Homologene: 75139
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to A, chromosome 1 at 34,228,369 bp
  • T to C, chromosome 1 at 63,477,757 bp
  • A to T, chromosome 1 at 83,209,266 bp
  • C to A, chromosome 1 at 139,168,952 bp
  • C to T, chromosome 1 at 175,609,778 bp
  • C to T, chromosome 2 at 5,862,706 bp
  • T to G, chromosome 2 at 5,932,482 bp
  • T to C, chromosome 2 at 24,348,599 bp
  • A to G, chromosome 2 at 67,512,615 bp
  • A to T, chromosome 2 at 120,986,626 bp
  • A to G, chromosome 2 at 127,577,954 bp
  • T to C, chromosome 2 at 130,544,104 bp
  • T to C, chromosome 2 at 181,588,415 bp
  • T to C, chromosome 3 at 10,182,510 bp
  • A to G, chromosome 3 at 91,088,457 bp
  • G to T, chromosome 3 at 93,651,923 bp
  • A to T, chromosome 3 at 103,993,882 bp
  • A to G, chromosome 3 at 125,874,135 bp
  • A to T, chromosome 3 at 154,594,446 bp
  • A to T, chromosome 4 at 44,138,748 bp
  • A to T, chromosome 4 at 46,544,050 bp
  • G to A, chromosome 4 at 108,856,210 bp
  • T to C, chromosome 4 at 115,863,026 bp
  • A to G, chromosome 4 at 124,715,901 bp
  • A to T, chromosome 4 at 145,155,857 bp
  • A to G, chromosome 4 at 150,644,277 bp
  • T to C, chromosome 5 at 29,206,688 bp
  • C to T, chromosome 5 at 35,512,428 bp
  • C to A, chromosome 5 at 137,578,921 bp
  • A to G, chromosome 5 at 138,255,792 bp
  • A to G, chromosome 6 at 50,320,074 bp
  • C to T, chromosome 6 at 89,574,363 bp
  • A to G, chromosome 6 at 121,668,547 bp
  • T to C, chromosome 6 at 122,079,639 bp
  • G to T, chromosome 6 at 148,425,918 bp
  • T to C, chromosome 7 at 12,493,688 bp
  • A to C, chromosome 7 at 19,074,076 bp
  • T to A, chromosome 7 at 35,200,298 bp
  • A to T, chromosome 7 at 43,299,630 bp
  • A to T, chromosome 7 at 55,264,302 bp
  • A to T, chromosome 7 at 132,262,850 bp
  • G to A, chromosome 8 at 10,594,905 bp
  • T to A, chromosome 8 at 43,650,827 bp
  • A to T, chromosome 8 at 43,651,815 bp
  • C to T, chromosome 8 at 95,040,544 bp
  • T to A, chromosome 8 at 112,815,496 bp
  • C to T, chromosome 9 at 22,129,604 bp
  • T to C, chromosome 10 at 39,097,138 bp
  • A to G, chromosome 10 at 71,159,523 bp
  • A to G, chromosome 11 at 51,007,675 bp
  • A to G, chromosome 11 at 54,657,263 bp
  • A to G, chromosome 11 at 60,706,016 bp
  • T to A, chromosome 11 at 75,545,741 bp
  • T to C, chromosome 11 at 110,069,863 bp
  • T to C, chromosome 12 at 10,391,162 bp
  • T to C, chromosome 13 at 11,731,723 bp
  • T to C, chromosome 13 at 93,711,370 bp
  • G to T, chromosome 14 at 101,902,302 bp
  • T to G, chromosome 15 at 9,663,194 bp
  • T to A, chromosome 15 at 80,395,044 bp
  • G to A, chromosome 15 at 89,473,539 bp
  • A to G, chromosome 16 at 12,267,756 bp
  • A to T, chromosome 16 at 19,566,437 bp
  • A to G, chromosome 16 at 35,836,129 bp
  • T to A, chromosome 16 at 43,649,218 bp
  • C to A, chromosome 17 at 18,325,801 bp
  • C to T, chromosome 17 at 18,586,402 bp
  • G to A, chromosome 17 at 24,217,949 bp
  • C to T, chromosome 17 at 25,777,470 bp
  • A to G, chromosome 17 at 35,150,126 bp
  • A to G, chromosome 18 at 32,246,610 bp
  • A to G, chromosome 19 at 6,128,066 bp
  • G to A, chromosome 19 at 21,848,040 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1943 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039961-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.