Strain Name:
C57BL/6J-MtgxR3881Btlr/Mmmh
Stock Number:
040795-MU
Citation ID:
RRID:MMRRC_040795-MU
Other Names:
R3881 (G1), C57BL/6J-MtgxR3881Btlr
Major Collection:

Gene Information

Esr2
Name: estrogen receptor 2 (beta)
Synonyms: ERbeta, ER beta, oestrogen receptor beta, Estrb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 13983
HGNC: HGNC:3468
Homologene: 1100
Hps5
Name: HPS5, biogenesis of lysosomal organelles complex 2 subunit 2
Synonyms: ruby eye 2, Hermansky-Pudlak syndrome 5, ru-2, ru2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 246694
Homologene: 35333
Gpd2
Name: glycerol phosphate dehydrogenase 2, mitochondrial
Synonyms: Gdm1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14571
HGNC: HGNC:4456
Homologene: 352
Icos
Name: inducible T cell co-stimulator
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 54167
HGNC: HGNC:5351
Homologene: 8097
Dgat2
Name: diacylglycerol O-acyltransferase 2
Synonyms: 0610010B06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 67800
Homologene: 23580
Actn4
Name: actinin alpha 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 60595
HGNC: HGNC:166
Homologene: 55857
Rpp38
Name: ribonuclease P/MRP 38 subunit
Synonyms: C330006A15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227522
Homologene: 4680
Enpp2
Name: ectonucleotide pyrophosphatase/phosphodiesterase 2
Synonyms: ATX, Autotaxin, PD-Ialpha, Npps2, Pdnp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 18606
HGNC: HGNC:3357
Homologene: 4526
Cep41
Name: centrosomal protein 41
Synonyms: 2810431D15Rik, Tsga14, 1700017E11Rik, Cep41
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 83922
Homologene: 10284
Zfp106
Name: zinc finger protein 106
Synonyms: Sh3bp3, sirm, H3a, Cd-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20402
Homologene: 40787
Ints4
Name: integrator complex subunit 4
Synonyms: 2610034N24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 101861
Homologene: 69427
Ube4b
Name: ubiquitination factor E4B
Synonyms: 4930551I19Rik, UFD2, 4933406G05Rik, D4Bwg0973e, UFD2a, Ufd2p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 63958
Homologene: 107623
Sdha
Name: succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
Synonyms: SDH2, FP, 2310034D06Rik, SDHF
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 66945
Homologene: 3073
Cyfip2
Name: cytoplasmic FMR1 interacting protein 2
Synonyms: 1500004I01Rik, 6430511D02Rik, Pir121
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 76884
Homologene: 7936
Ipo13
Name: importin 13
Synonyms: Kap13, Imp13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230673
Homologene: 40968
Mcm3ap
Name: minichromosome maintenance complex component 3 associated protein
Synonyms: GANP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 54387
VEGA: 10
HGNC: HGNC:6946
Homologene: 2902
Mier2
Name: MIER family member 2
Synonyms: 2700087H15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 70427
Homologene: 18941
Kcnh5
Name: potassium voltage-gated channel, subfamily H (eag-related), member 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238271
VEGA: 12
HGNC: HGNC:6254
Homologene: 15858
Rplp1
Name: ribosomal protein, large, P1
Synonyms: acidic ribosomal phosphoprotein P1, C430017H15Rik, 2410042H16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 56040
VEGA: 9
Homologene: 137330
Aptx
Name: aprataxin
Synonyms: 2410016G21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 66408
Homologene: 41634
Jup
Name: junction plakoglobin
Synonyms: PG, plakoglobin, Ctnng, gamma-catenin, D930025P04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16480
HGNC: HGNC:6207
Homologene: 1680
Angptl4
Name: angiopoietin-like 4
Synonyms: NG27, HFARP, BK89, FIAF
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 57875
Homologene: 10755
Clca4a
Name: chloride channel accessory 4A
Synonyms: 9130020L07Rik, Clca6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 99663
HGNC: HGNC:2018
Homologene: 40808
Recql5
Name: RecQ protein-like 5
Synonyms: Recql5b, Recq5b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 170472
HGNC: HGNC:9950
Homologene: 31232
Itsn2
Name: intersectin 2
Synonyms: Eh domain, SH3 domain regulator of endocytosis 2, Ese2, Sh3d1B, Sh3p18
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 20403
VEGA: 12
HGNC: HGNC:6184
Homologene: 22627
Paxip1
Name: PAX interacting (with transcription-activation domain) protein 1
Synonyms: PTIP, D5Ertd149e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 55982
HGNC: HGNC:8624
Timm50
Name: translocase of inner mitochondrial membrane 50
Synonyms: TIM50L, 2810403L02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 66525
Homologene: 57031
Cep95
Name: centrosomal protein 95
Synonyms: 4732496G21Rik, F630025I20Rik, Ccdc45
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 320162
Homologene: 16297
Fam13b
Name: family with sequence similarity 13, member B
Synonyms: 2610024E20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225358
VEGA: 18
HGNC: HGNC:1335
Homologene: 9585
Itpr3
Name: inositol 1,4,5-triphosphate receptor 3
Synonyms: Itpr-3, tf, Ip3r3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 16440
HGNC: HGNC:6182
Homologene: 1675
Myo6
Name: myosin VI
Synonyms: Myo6rsv, rsv, Tlc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 17920
HGNC: HGNC:7605
Homologene: 56417
Fbn1
Name: fibrillin 1
Synonyms: Fib-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14118
HGNC: HGNC:3603
Homologene: 30958
Dnah10
Name: dynein, axonemal, heavy chain 10
Synonyms: Dnahc10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 56087
HGNC: HGNC:2941
Homologene: 25816
Dnah2
Name: dynein, axonemal, heavy chain 2
Synonyms: D330014H01Rik, Dnahc2, Dnhd3, 2900022L05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 327954
HGNC: HGNC:2948
Homologene: 72110
Def6
Name: differentially expressed in FDCP 6
Synonyms: 2410003F05Rik, IBP, SLAT, IRF-4-binding protein, 6430538D02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 23853
HGNC: HGNC:2760
Homologene: 11103
9530053A07Rik
Name: RIKEN cDNA 9530053A07 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 319482
Homologene: 130055
Kif1a
Name: kinesin family member 1A
Synonyms: C630002N23Rik, Kns1, ATSV, LOC381283, N-3 kinesin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 16560
HGNC: HGNC:888
Homologene: 99729
Letm2
Name: leucine zipper-EF-hand containing transmembrane protein 2
Synonyms: D030041N04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 270035
Homologene: 56358
Fbxw14
Name: F-box and WD-40 domain protein 14
Synonyms: E330009N23Rik, Fbxo12, Fbx12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 50757
Homologene: 110776
Shank2
Name: SH3 and multiple ankyrin repeat domains 2
Synonyms: ProSAP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 210274
Homologene: 105965
Olfr1331
Name: olfactory receptor 1331
Synonyms: GA_x6K02T2QD9B-18670866-18669913, MOR259-3P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 258159
Homologene: 134082
Mroh3
Name: maestro heat-like repeat family member 3
Synonyms: 2310006M14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 76422
Nin
Name: ninein
Synonyms: 3110068G20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 18080
Homologene: 40632
Ttc28
Name: tetratricopeptide repeat domain 28
Synonyms: 2310015L07Rik, TPRBK
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 209683
Homologene: 41023
Rnf180
Name: ring finger protein 180
Synonyms: 3110001E11Rik, Rines
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 71816
VEGA: 13
Homologene: 18677
4933402N03Rik
Name: RIKEN cDNA 4933402N03 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233918
Homologene: 52852
Dlgap1
Name: DLG associated protein 1
Synonyms: D17Bwg0511e, 4933422O14Rik, SAPAP1, Gkap, DAP-1 beta, GKAP/SAPAP, Sapap1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224997
HGNC: HGNC:2905
Homologene: 31258
Zdhhc22
Name: zinc finger, DHHC-type containing 22
Synonyms: LOC238331
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238331
VEGA: 12
Homologene: 45486
Ocln
Name: occludin
Synonyms: Ocl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 18260
HGNC: HGNC:8104
Homologene: 1905
Cyp2d34
Name: cytochrome P450, family 2, subfamily d, polypeptide 34
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223706
VEGA: 15
Homologene: 86099
Tmprss11a
Name: transmembrane protease, serine 11a
Synonyms: LOC194597
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 194597
Homologene: 62723
Myoz2
Name: myozenin 2
Synonyms: Fatz-2, calsarcin-1, 1110012I24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 59006
HGNC: HGNC:1330
Homologene: 9583
Olfr1495
Name: olfactory receptor 1495
Synonyms: MOR266-9, GA_x6K02T2RE5P-4101369-4102328
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258341
Homologene: 73965
Ly6c1
Name: lymphocyte antigen 6 complex, locus C1
Synonyms: Ly-6C, Ly6c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 17067
Homologene: 113718
Olfr154
Name: olfactory receptor 154
Synonyms: 912-93, MOR175-1, Olfr4-3, GA_x6K02T2Q125-47143827-47142871, OR93
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 27216
Homologene: 104131
Nr2f6
Name: nuclear receptor subfamily 2, group F, member 6
Synonyms: Erbal2, COUP-TF3, EAR2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 13864
HGNC: HGNC:7977
Homologene: 7706
Tex11
Name: testis expressed gene 11
Synonyms: 4930565P14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 83558
Homologene: 49962
Zfp88
Name: withdrawn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: UN
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 60,997,697 bp
  • A to G, chromosome 1 at 93,082,301 bp
  • A to T, chromosome 1 at 136,192,257 bp
  • T to A, chromosome 2 at 3,329,246 bp
  • C to T, chromosome 2 at 57,338,975 bp
  • T to A, chromosome 2 at 85,664,425 bp
  • A to G, chromosome 2 at 120,532,149 bp
  • A to T, chromosome 2 at 125,367,571 bp
  • T to C, chromosome 3 at 123,013,720 bp
  • T to C, chromosome 3 at 144,957,318 bp
  • A to G, chromosome 4 at 40,702,709 bp
  • A to G, chromosome 4 at 117,897,756 bp
  • A to G, chromosome 4 at 118,869,353 bp
  • A to T, chromosome 4 at 149,365,404 bp
  • C to T, chromosome 5 at 27,748,839 bp
  • C to T, chromosome 5 at 86,445,805 bp
  • A to T, chromosome 5 at 111,183,240 bp
  • T to C, chromosome 5 at 124,773,031 bp
  • A to G, chromosome 6 at 30,658,398 bp
  • T to A, chromosome 7 at 28,140,038 bp
  • C to A, chromosome 7 at 28,311,007 bp
  • G to A, chromosome 7 at 28,898,266 bp
  • A to G, chromosome 7 at 46,771,996 bp
  • A to G, chromosome 7 at 97,516,257 bp
  • G to A, chromosome 7 at 99,169,743 bp
  • T to C, chromosome 7 at 131,139,094 bp
  • T to C, chromosome 7 at 144,405,384 bp
  • C to A, chromosome 8 at 25,593,868 bp
  • C to T, chromosome 8 at 71,376,031 bp
  • A to G, chromosome 9 at 61,914,422 bp
  • A to G, chromosome 9 at 80,264,256 bp
  • A to T, chromosome 9 at 109,271,194 bp
  • G to A, chromosome 10 at 76,506,446 bp
  • C to T, chromosome 10 at 79,548,750 bp
  • A to G, chromosome 11 at 46,208,335 bp
  • T to A, chromosome 11 at 69,451,347 bp
  • A to G, chromosome 11 at 100,378,381 bp
  • A to G, chromosome 11 at 106,806,292 bp
  • G to A, chromosome 11 at 115,893,954 bp
  • G to T, chromosome 11 at 115,893,955 bp
  • G to A, chromosome 12 at 4,634,546 bp
  • C to T, chromosome 12 at 70,042,541 bp
  • A to T, chromosome 12 at 75,130,891 bp
  • T to C, chromosome 12 at 76,167,620 bp
  • T to A, chromosome 12 at 86,983,626 bp
  • G to T, chromosome 13 at 74,339,192 bp
  • A to G, chromosome 13 at 100,511,635 bp
  • A to T, chromosome 13 at 105,250,407 bp
  • A to G, chromosome 15 at 54,919,692 bp
  • A to G, chromosome 15 at 65,014,867 bp
  • T to C, chromosome 15 at 75,045,587 bp
  • T to A, chromosome 15 at 82,618,617 bp
  • A to G, chromosome 17 at 27,113,840 bp
  • T to C, chromosome 17 at 28,220,215 bp
  • G to A, chromosome 17 at 33,777,034 bp
  • T to A, chromosome 17 at 70,786,815 bp
  • A to T, chromosome 18 at 34,462,059 bp
  • T to C, chromosome 19 at 13,768,780 bp
  • C to A, chromosome X at 100,933,415 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3881 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040795-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.