Strain Name:
C57BL/6J-MtgxR4922Btlr/Mmmh
Stock Number:
042524-MU
Citation ID:
RRID:MMRRC_042524-MU
Other Names:
R4922 (G1), C57BL/6J-MtgxR4922Btlr
Major Collection:

Strain Information

Enc1
Name: ectodermal-neural cortex 1
Synonyms: PIG10, Nrpb
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 13803
VEGA: 13
HGNC: HGNC:3345
Homologene: 2694
Lrrn1
Name: leucine rich repeat protein 1, neuronal
Synonyms: NLRR-1, 2810047E21Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16979
Homologene: 32036
Bmerb1
Name: bMERB domain containing 1
Synonyms: MINP, 2900011O08Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 67254
Homologene: 13236
Zmynd8
Name: zinc finger, MYND-type containing 8
Synonyms: 1110013E22Rik, 2010005I16Rik, ZMYND8, RACK7, 3632413B07Rik, Prkcbp1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228880
HGNC: HGNC:9397
Homologene: 32679
Rnf145
Name: ring finger protein 145
Synonyms: 3732413I11Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 74315
Homologene: 14427
Fancd2
Name: Fanconi anemia, complementation group D2
Synonyms: 2410150O07Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 211651
HGNC: HGNC:3585
Homologene: 13212
Prex2
Name: phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
Synonyms: 6230420N16Rik, C030045D06Rik, Depdc2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 109294
Homologene: 23523
Mtcl1
Name: microtubule crosslinking factor 1
Synonyms: t8219b25, 1110012J17Rik, Soga2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 68617
Homologene: 41017
Kntc1
Name: kinetochore associated 1
Synonyms: jgl
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 208628
Homologene: 32227
Atf7ip
Name: activating transcription factor 7 interacting protein
Synonyms: ATFa-associated Modulator, AM, 2610204M12Rik, Mcaf1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 54343
Homologene: 10051
Dcaf8
Name: DDB1 and CUL4 associated factor 8
Synonyms: H326, D1Ucla4, D1Dau35e, Wdr42a
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 98193
Homologene: 56725
Bltp1
Name: bridge-like lipid transfer protein family member 1
Synonyms: Tweek, FSA, 4932438A13Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229227
Homologene: 52105
Ryr2
Name: ryanodine receptor 2, cardiac
Synonyms: 9330127I20Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 20191
VEGA: 13
Homologene: 37423
Bmpr2
Name: bone morphogenetic protein receptor type 2
Synonyms: BMPR-II, BMP-2, 2610024H22Rik, BMPRII
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12168
HGNC: HGNC:1078
Homologene: 929
Cic
Name: capicua transcriptional repressor
Synonyms: 1200010B10Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 71722
Homologene: 87637
Bcl2
Name: B cell leukemia/lymphoma 2
Synonyms: Bcl-2, C430015F12Rik, D830018M01Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12043
HGNC: HGNC:990
Homologene: 527
Adgrb2
Name: adhesion G protein-coupled receptor B2
Synonyms: Bai2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230775
HGNC: HGNC:944
Homologene: 1288
Dennd1b
Name: DENN domain containing 1B
Synonyms: F730008N07Rik, 4632404N19Rik, 4930467M19Rik, 6820401H01Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 329260
Homologene: 11739
Ptk7
Name: PTK7 protein tyrosine kinase 7
Synonyms: 8430404F20Rik, mPTK7/CCK4, chz
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 71461
VEGA: 17
HGNC: HGNC:9618
Homologene: 43672
Cemip
Name: cell migration inducing protein, hyaluronan binding
Synonyms: 12H19.01.T7, 6330404C01Rik, 9930013L23Rik, Hybid
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 80982
Homologene: 10268
Prune2
Name: prune homolog 2
Synonyms: 6330414G02Rik, A330102H22Rik, A230083H22Rik, Olfaxin
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 353211
VEGA: 19
Homologene: 18939
Cd200r1
Name: CD200 receptor 1
Synonyms: OX2R, CD200R, Mox2r
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 57781
Homologene: 10957
Il6st
Name: interleukin 6 signal transducer
Synonyms: gp130, CD130, D13Ertd699e, 5133400A03Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 16195
HGNC: HGNC:6021
Homologene: 1645
Tcp1
Name: t-complex protein 1
Synonyms: Ccta, c-cpn, TRic, CCT, Tcp-1, Tp63, p63, Cct1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 21454
Homologene: 5656
Sorl1
Name: sortilin-related receptor, LDLR class A repeats-containing
Synonyms: LR11, mSorLA, 2900010L19Rik, Sorla
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 20660
Homologene: 2336
Cpsf3
Name: cleavage and polyadenylation specificity factor 3
Synonyms: 73 kDa
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 54451
VEGA: 12
HGNC: HGNC:2326
Homologene: 6499
Wdr75
Name: WD repeat domain 75
Synonyms: 1300003A18Rik, 2410118I19Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 73674
Homologene: 32771
Fancm
Name: Fanconi anemia, complementation group M
Synonyms: C730036B14Rik, D12Ertd364e
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 104806
VEGA: 12
Homologene: 35378
Akap11
Name: A kinase anchor protein 11
Synonyms: 6330501D17Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 219181
HGNC: HGNC:369
Homologene: 8279
Hectd4
Name: HECT domain E3 ubiquitin protein ligase 4
Synonyms: Gm15800
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 269700
Homologene: 28297
Pde4a
Name: phosphodiesterase 4A, cAMP specific
Synonyms: dunce, Dpde2, D9Ertd60e
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 18577
HGNC: HGNC:8780
Homologene: 4520
Tsc2
Name: TSC complex subunit 2
Synonyms: tuberin, Nafld, tuberous sclerosis 2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 22084
VEGA: 17
Homologene: 462
Kctd18
Name: potassium channel tetramerisation domain containing 18
Synonyms: 4932411A20Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 51960
Homologene: 12710
Gm1965
Name: predicted gene 1965
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 434065
Snapc4
Name: small nuclear RNA activating complex, polypeptide 4
Synonyms: 5730436L13Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227644
Homologene: 2321
Naip2
Name: NLR family, apoptosis inhibitory protein 2
Synonyms: Naip2, Naip-rs6, Birc1b
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 17948
HGNC: HGNC:7634
Homologene: 136092
Cyp4a10
Name: cytochrome P450, family 4, subfamily a, polypeptide 10
Synonyms: RP1, Cyp4a, D4Rp1, Msp-3
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 13117
HGNC: HGNC:2642
Homologene: 128044
Zfp629
Name: zinc finger protein 629
Synonyms: 9330199A09Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 320683
Homologene: 65318
Anxa3
Name: annexin A3
Synonyms: Anx3
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 11745
HGNC: HGNC:541
Homologene: 68445
Tmem30b
Name: transmembrane protein 30B
Synonyms: 9130011B11Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238257
VEGA: 12
Homologene: 133755
Hal
Name: histidine ammonia lyase
Synonyms: histidase, Hsd
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 15109
HGNC: HGNC:4806
Homologene: 68229
Ttc21b
Name: tetratricopeptide repeat domain 21B
Synonyms: 2410066K11Rik, line 158, Thm1, aln
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 73668
Homologene: 57006
Cfap251
Name: cilia and flagella associated protein 251
Synonyms: 4930415N18Rik, 4933428F06Rik, Wdr66
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 269701
Homologene: 16964
Albfm1
Name: albumin superfamily member 1
Synonyms: ARG, Gm17754, 5830473C10Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 622307
Homologene: 129803
Arfgef3
Name: ARFGEF family member 3
Synonyms: B930094H20Rik, D10Bwg1379e, BIG3
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 215821
VEGA: 10
Homologene: 41366
Cfap52
Name: cilia and flagella associated protein 52
Synonyms: 4933417B11Rik, 1700019F09Rik, Wdr16
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 71860
Homologene: 12416
Dpp10
Name: dipeptidylpeptidase 10
Synonyms: DPRP3, 6430601K09Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 269109
Homologene: 41400
Col15a1
Name: collagen, type XV, alpha 1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 12819
HGNC: HGNC:2192
Homologene: 1396
Snx19
Name: sorting nexin 19
Synonyms: 3526401K03Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 102607
VEGA: 9
Homologene: 8846
Nxpe3
Name: neurexophilin and PC-esterase domain family, member 3
Synonyms: LOC208684, LOC385658, Fam55c
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 385658
VEGA: 16
Homologene: 17030
Csf2rb
Name: colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
Synonyms: AIC2B, common beta chain, CDw131, beta c, Bc, Il5rb, Il3r, Il3rb1, Csf2rb1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 12983
VEGA: 15
HGNC: HGNC:2436
Homologene: 339
Hs3st4
Name: heparan sulfate (glucosamine) 3-O-sulfotransferase 4
Synonyms: Gm6915
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 628779
HGNC: HGNC:5200
Homologene: 82444
Dnase2a
Name: deoxyribonuclease II alpha
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 13423
HGNC: HGNC:2960
Homologene: 68179
Vmn1r10
Name: vomeronasal 1 receptor 10
Synonyms: V1rc1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 113858
Homologene: 76459
Chml
Name: choroideremia-like
Synonyms: Rep2, E030003F13Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12663
HGNC: HGNC:1941
Homologene: 31055
Wdr27
Name: WD repeat domain 27
Synonyms: 0610012K18Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 71682
VEGA: 17
Homologene: 18417
Rgl2
Name: ral guanine nucleotide dissociation stimulator-like 2
Synonyms: Rlf, KE1.5, Rab2l, Rgt2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 19732
HGNC: HGNC:9769
Homologene: 3494
Ugt2b36
Name: UDP glucuronosyltransferase 2 family, polypeptide B36
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231396
Homologene: 128251
Drgx
Name: dorsal root ganglia homeobox
Synonyms: Drg11, Prrxl1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 107751
Sp110
Name: Sp110 nuclear body protein
Synonyms: 52kDa, Ipr1, 5031415C07Rik, 5830484A20Rik, Ifi75
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 109032
HGNC: HGNC:5401
Homologene: 82192
Cyp21a1
Name: cytochrome P450, family 21, subfamily a, polypeptide 1
Synonyms: 21-OH, 21-hydroxylase, 21OH, Oh21-1, 21OHA, Cyp21, Oh21-1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 13079
Homologene: 68063
Mylip
Name: myosin regulatory light chain interacting protein
Synonyms: Mir, 9430057C20Rik, Idol
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218203
VEGA: 13
Homologene: 8309
Clec12a
Name: C-type lectin domain family 12, member a
Synonyms: Micl
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232413
Homologene: 51378
Or11i1
Name: olfactory receptor family 11 subfamily I member 1
Synonyms: GA_x6K02T2N6GK-529983-529033, MOR122-2, Olfr266
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 258482
Homologene: 51728
Ncoa4-ps
Name: nuclear receptor coactivator 4, pseudogene
Synonyms: Gm6768
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 627557
VEGA: 12
Speer4a2
Name: spermatogenesis associated glutamate (E)-rich protein 4A2
Synonyms: Gm10471
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100039045
Homologene: 69402
Fbxo16
Name: F-box protein 16
Synonyms: Fbx16
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 50759
VEGA: 14
Homologene: 9273
Bmp10
Name: bone morphogenetic protein 10
Synonyms: b2b2711Clo
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 12154
Homologene: 7644
Or4c15b
Name: olfactory receptor family 4 subfamily C member 15B
Synonyms: GA_x6K02T2Q125-50727797-50726862, MOR233-22, MOR233-19, Olfr1229
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 257921
Homologene: 79376
Trbv12-2
Name: T cell receptor beta, variable 12-2
Synonyms: Tcrb-V5.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 100124674
Sgo2b
Name: shugoshin 2B
Synonyms: Gm4975, Sgol2b
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244495
Homologene: 51867
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 11,169,940 bp
  • T to C, chromosome 1 at 45,816,478 bp
  • A to C, chromosome 1 at 57,965,548 bp
  • A to G, chromosome 1 at 59,867,424 bp
  • C to G, chromosome 1 at 85,589,118 bp
  • T to C, chromosome 1 at 92,644,368 bp
  • T to A, chromosome 1 at 94,022,478 bp
  • C to A, chromosome 1 at 106,712,646 bp
  • T to C, chromosome 1 at 123,378,153 bp
  • T to C, chromosome 1 at 139,085,914 bp
  • C to T, chromosome 1 at 172,186,335 bp
  • A to G, chromosome 1 at 174,609,851 bp
  • T to C, chromosome 1 at 175,687,146 bp
  • A to G, chromosome 2 at 26,369,233 bp
  • A to G, chromosome 2 at 66,242,771 bp
  • A to T, chromosome 2 at 89,282,467 bp
  • T to C, chromosome 2 at 165,812,392 bp
  • T to A, chromosome 3 at 36,987,165 bp
  • A to T, chromosome 3 at 106,822,260 bp
  • T to C, chromosome 4 at 47,258,719 bp
  • T to A, chromosome 4 at 101,835,532 bp
  • C to A, chromosome 4 at 115,521,094 bp
  • G to T, chromosome 4 at 130,007,852 bp
  • T to A, chromosome 5 at 21,995,587 bp
  • A to T, chromosome 5 at 26,084,793 bp
  • T to C, chromosome 5 at 87,066,324 bp
  • A to G, chromosome 5 at 90,579,711 bp
  • A to T, chromosome 5 at 96,820,429 bp
  • T to C, chromosome 5 at 121,359,315 bp
  • T to C, chromosome 5 at 123,256,053 bp
  • T to A, chromosome 5 at 123,802,246 bp
  • G to T, chromosome 6 at 41,119,147 bp
  • T to A, chromosome 6 at 57,113,826 bp
  • C to T, chromosome 6 at 87,433,575 bp
  • T to C, chromosome 6 at 89,146,543 bp
  • A to T, chromosome 6 at 107,568,350 bp
  • T to C, chromosome 6 at 113,585,473 bp
  • A to G, chromosome 6 at 129,359,478 bp
  • A to T, chromosome 6 at 136,560,041 bp
  • TCCCCC to TCCCCCCCC, chromosome 7 at 25,291,670 bp
  • T to A, chromosome 7 at 83,947,100 bp
  • G to T, chromosome 7 at 124,397,187 bp
  • A to G, chromosome 7 at 127,612,127 bp
  • A to T, chromosome 8 at 63,926,630 bp
  • A to G, chromosome 8 at 84,908,996 bp
  • T to C, chromosome 9 at 21,210,713 bp
  • T to A, chromosome 9 at 30,437,467 bp
  • C to A, chromosome 9 at 42,014,450 bp
  • T to A, chromosome 10 at 18,592,186 bp
  • A to T, chromosome 10 at 93,503,539 bp
  • T to A, chromosome 11 at 44,557,236 bp
  • A to G, chromosome 11 at 67,931,722 bp
  • T to C, chromosome 12 at 21,301,537 bp
  • G to A, chromosome 12 at 65,106,892 bp
  • G to A, chromosome 12 at 73,545,714 bp
  • A to G, chromosome 12 at 119,262,517 bp
  • T to C, chromosome 13 at 11,709,963 bp
  • G to A, chromosome 13 at 45,408,762 bp
  • C to T, chromosome 13 at 97,245,735 bp
  • T to C, chromosome 13 at 100,154,960 bp
  • C to T, chromosome 13 at 112,502,865 bp
  • A to T, chromosome 14 at 32,608,406 bp
  • C to T, chromosome 14 at 65,299,208 bp
  • A to T, chromosome 14 at 78,512,780 bp
  • T to A, chromosome 15 at 78,346,467 bp
  • A to G, chromosome 16 at 13,986,819 bp
  • A to T, chromosome 16 at 44,789,676 bp
  • T to C, chromosome 16 at 55,860,324 bp
  • A to G, chromosome 17 at 12,919,863 bp
  • C to A, chromosome 17 at 14,920,754 bp
  • T to A, chromosome 17 at 24,600,369 bp
  • A to G, chromosome 17 at 33,932,775 bp
  • G to A, chromosome 17 at 34,803,393 bp
  • C to A, chromosome 17 at 46,576,491 bp
  • A to C, chromosome 17 at 66,348,479 bp
  • A to T, chromosome 19 at 17,122,752 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4922 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
042524-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.