Strain Name:
C57BL/6J-MtgxR5076Btlr/Mmmh
Stock Number:
042665-MU
Citation ID:
RRID:MMRRC_042665-MU
Other Names:
R5076 (G1), C57BL/6J-MtgxR5076Btlr
Major Collection:

Strain Information

Capzb
Name: capping actin protein of muscle Z-line subunit beta
Synonyms: CPbeta1, Cappb1, CPB1, CPB2, CPbeta2, 1700120C01Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 12345
HGNC: HGNC:1491
Homologene: 3620
Pitpnc1
Name: phosphatidylinositol transfer protein, cytoplasmic 1
Synonyms: C330017I21Rik, 1110020B03Rik, RDGB-BETA, RDGBB1, 5830436L09Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 71795
Homologene: 138301
Pdss1
Name: prenyl (solanesyl) diphosphate synthase, subunit 1
Synonyms: mSPS1, 2700031G06Rik, 2610203G20Rik, Tprt
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 56075
Homologene: 5353
Mllt6
Name: myeloid/lymphoid or mixed-lineage leukemia; translocated to, 6
Synonyms: Af17
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 246198
HGNC: HGNC:7138
Homologene: 31347
Itpr1
Name: inositol 1,4,5-trisphosphate receptor 1
Synonyms: Pcp-1, Pcp1, IP3R1, InsP3R type I, P400, Ip3r, opt, wblo, Itpr-1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16438
HGNC: HGNC:6180
Homologene: 1673
Zfyve1
Name: zinc finger, FYVE domain containing 1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217695
VEGA: 12
Homologene: 10945
Mrps5
Name: mitochondrial ribosomal protein S5
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 77721
Homologene: 32726
Kif2c
Name: kinesin family member 2C
Synonyms: 4930402F02Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 73804
HGNC: HGNC:6393
Homologene: 21355
Tasor2
Name: transcription activation suppressor family member 2
Synonyms: Fam208b, BC016423
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 105203
VEGA: 13
Homologene: 26435
Robo3
Name: roundabout guidance receptor 3
Synonyms: Robo3a, Rbig1, Rig1, Rig-1, Robo3b
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 19649
Homologene: 32119
Peg3
Name: paternally expressed 3
Synonyms: Gcap4, End4, Pw1, Zfp102
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18616
HGNC: HGNC:8826
Homologene: 31363
Ppfia1
Name: protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
Synonyms: Liprin-alpha1, liprin, C030014K08Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233977
HGNC: HGNC:9245
Homologene: 20802
Acp6
Name: acid phosphatase 6, lysophosphatidic
Synonyms: ACPL1, 5730559A09Rik, mPACPL1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 66659
Homologene: 41128
Hjurp
Name: Holliday junction recognition protein
Synonyms: 6430706D22Rik, A730008H23Rik, C330011F01Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 381280
Homologene: 10184
Mindy1
Name: MINDY lysine 48 deubiquitinase 1
Synonyms: 4930504E06Rik, NF-E2 inducible protein, Fam63a, 1810005H09Rik, cI-40
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 75007
Homologene: 32409
Pnisr
Name: PNN interacting serine/arginine-rich
Synonyms: Sfrs18, 5730406M06Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 66625
Homologene: 32802
Trappc6b
Name: trafficking protein particle complex 6B
Synonyms: 5830498C14Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 78232
VEGA: 12
Homologene: 42466
Cd34
Name: CD34 antigen
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12490
HGNC: HGNC:1662
Homologene: 1343
Adgrd1
Name: adhesion G protein-coupled receptor D1
Synonyms: E230012M21Rik, Gpr133
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 243277
Homologene: 34616
Epb41l4b
Name: erythrocyte membrane protein band 4.1 like 4b
Synonyms: Lulu2, D4Ertd346e, 6430543G08Rik, Ehm2, Epb4.1l4b
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 54357
Homologene: 69270
Ppp1r3a
Name: protein phosphatase 1, regulatory subunit 3A
Synonyms: GM, RGL
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 140491
HGNC: HGNC:9291
Homologene: 48124
Dnah14
Name: dynein, axonemal, heavy chain 14
Synonyms: LOC381311, Gm980, A230079K17Rik, Dnahc14
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 240960
HGNC: HGNC:2945
Homologene: 90078
Insrr
Name: insulin receptor-related receptor
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 23920
HGNC: HGNC:6093
Homologene: 56539
Or4f6
Name: olfactory receptor family 4 subfamily F member 6
Synonyms: Olfr1310, GA_x6K02T2Q125-73056609-73055671, MOR245-3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258441
Homologene: 74053
Tcaf2
Name: TRPM8 channel-associated factor 2
Synonyms: Fam115c
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232748
Homologene: 17147
Klrb1-ps1
Name: killer cell lectin-like receptor subfamily B member 1, pseudogene 1
Synonyms: Nkrp1e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 724020
Krtap9-5
Name: keratin associated protein 9-5
Synonyms: OTTMUSG00000002205
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 435286
Homologene: 135766
Spock3
Name: sparc/osteonectin, cwcv and kazal-like domains proteoglycan 3
Synonyms: testican 3, 2900045C01Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 72902
Homologene: 9662
Vrtn
Name: vertebrae development associated
Synonyms: 7420416P09Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 432677
VEGA: 12
Homologene: 41236
Unc5d
Name: unc-5 netrin receptor D
Synonyms: D930029E11Rik, Unc5h4
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 210801
Homologene: 15450
Gpi-ps
Name: glucose-6-phosphate isomerase, pseudogene
Synonyms: LOC233995, Gm1840
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 669429
Sh3rf2
Name: SH3 domain containing ring finger 2
Synonyms: 9130023G24Rik, RNF158
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 269016
Homologene: 17618
Pdhx
Name: pyruvate dehydrogenase complex, component X
Synonyms: Pdx1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 27402
Homologene: 55757
Mdga1
Name: MAM domain containing glycosylphosphatidylinositol anchor 1
Synonyms: Mamdc3, 1200011I03Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 74762
Homologene: 17780
Tmem163
Name: transmembrane protein 163
Synonyms: 2610024A01Rik, SV31
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 72160
Homologene: 12798
Zfp788
Name: zinc finger protein 788
Synonyms: 2810426N06Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 67607
Homologene: 137363
Krtap4-23
Name: keratin associated protein 4-23
Synonyms: Gm11596
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 670464
Homologene: 124486
Lrrc39
Name: leucine rich repeat containing 39
Synonyms: 2010005E21Rik, 9430028I06Rik, Myomasp
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 109245
Homologene: 13668
Vmn1r184
Name: vomeronasal 1 receptor, 184
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 100312477
Homologene: 74353
Cdh15
Name: cadherin 15
Synonyms: M cadherin, Mcad, Cdh14
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 12555
HGNC: HGNC:1754
Homologene: 3622
Emilin3
Name: elastin microfibril interfacer 3
Synonyms: EMILIN-T, 1110013O17Rik, Emilin5
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 280635
Homologene: 18817
Dhrs7
Name: dehydrogenase/reductase 7
Synonyms: 2310016E22Rik, retSDR4, 5730564L20Rik, retDSR4, dehydrogenase/reductase (SDR family) member 7
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 66375
VEGA: 12
Homologene: 9350
Cplane2
Name: ciliogenesis and planar polarity effector 2
Synonyms: LOC279260, 6330545A04Rik, b2b2804Clo, b2b2827Clo, Rsg1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 76166
Homologene: 12793
Aadacl3
Name: arylacetamide deacetylase like 3
Synonyms: LOC230883
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230883
Homologene: 28426
Entpd8
Name: ectonucleoside triphosphate diphosphohydrolase 8
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 72090
Homologene: 77857
Ccdc17
Name: coiled-coil domain containing 17
Synonyms: 1100001F07Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 622665
Homologene: 77410
Clstn2
Name: calsyntenin 2
Synonyms: Cst-2, CSTN2, CS2, 2900042C18Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 64085
Homologene: 49698
Poc1b
Name: POC1 centriolar protein B
Synonyms: Wdr51b, 4933430F16Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 382406
Homologene: 41728
Or10ad1b
Name: olfactory receptor family 10 subfamily AD member 1B
Synonyms: Olfr286, MOR286-2, EG629524, GA_x6K02T2NBG7-5528233-5529186
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 629524
Homologene: 134078
Ctsw
Name: cathepsin W
Synonyms: lymphopain
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 13041
VEGA: 19
HGNC: HGNC:2546
Homologene: 37471
Ehd1
Name: EH-domain containing 1
Synonyms: RME-1, Past1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 13660
HGNC: HGNC:3242
Homologene: 81678
Chil4
Name: chitinase-like 4
Synonyms: Chi3l4, Ym2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 104183
Homologene: 74931
Ak1
Name: adenylate kinase 1
Synonyms: B430205N08Rik, Ak-1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 11636
HGNC: HGNC:361
Homologene: 20135
Pdxk
Name: pyridoxal (pyridoxine, vitamin B6) kinase
Synonyms: 2310036D04Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216134
HGNC: HGNC:8819
Homologene: 2731
H2-Q4
Name: histocompatibility 2, Q region locus 4
Synonyms: H-2Q4, Qb1, Qat-4, Qa4, Qa-4, Qb-1, H2-Gs10
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 15015
Homologene: 128352
Eif5a2
Name: eukaryotic translation initiation factor 5A2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 208691
HGNC: HGNC:3301
Homologene: 1490
4933434E20Rik
Name: RIKEN cDNA 4933434E20 gene
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99650
Homologene: 41041
Or4a79
Name: olfactory receptor family 4 subfamily A member 79
Synonyms: Olfr1252, MOR231-22_p, GA_x6K02T2Q125-51162884-51161940
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 404331
Homologene: 128094
Ube2nl
Name: ubiquitin-conjugating enzyme E2N-like
Synonyms: EG620934
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 620934
Pcdhgb1
Name: protocadherin gamma subfamily B, 1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93699
HGNC: HGNC:8708
Homologene: 81867
Mrpl33
Name: mitochondrial ribosomal protein L33
Synonyms: 0610009M10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 66845
Homologene: 81733
Muc3a
Name: mucin 3A, cell surface associated
Synonyms: A630081J09Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 619309
Homologene: 133536
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • GT to GTT, chromosome 1 at 88,266,524 bp
  • A to T, chromosome 1 at 127,500,276 bp
  • A to G, chromosome 1 at 181,757,234 bp
  • A to T, chromosome 1 at 194,948,030 bp
  • A to G, chromosome 2 at 22,899,917 bp
  • A to G, chromosome 2 at 25,085,054 bp
  • T to C, chromosome 2 at 32,633,448 bp
  • T to A, chromosome 2 at 89,721,401 bp
  • T to C, chromosome 2 at 103,041,077 bp
  • A to T, chromosome 2 at 112,008,592 bp
  • T to A, chromosome 2 at 127,600,852 bp
  • T to A, chromosome 2 at 160,909,318 bp
  • G to A, chromosome 3 at 28,782,737 bp
  • C to T, chromosome 3 at 87,802,629 bp
  • A to G, chromosome 3 at 90,056,252 bp
  • G to A, chromosome 3 at 95,295,399 bp
  • T to A, chromosome 3 at 97,167,989 bp
  • A to G, chromosome 3 at 106,202,597 bp
  • A to T, chromosome 3 at 116,579,540 bp
  • T to A, chromosome 4 at 21,874,990 bp
  • C to T, chromosome 4 at 57,040,984 bp
  • A to T, chromosome 4 at 116,599,021 bp
  • A to T, chromosome 4 at 117,174,869 bp
  • A to T, chromosome 4 at 139,287,814 bp
  • A to G, chromosome 4 at 141,217,385 bp
  • G to A, chromosome 4 at 144,456,070 bp
  • T to A, chromosome 5 at 31,650,451 bp
  • A to T, chromosome 5 at 129,143,989 bp
  • T to A, chromosome 5 at 137,210,540 bp
  • A to G, chromosome 6 at 14,754,681 bp
  • T to C, chromosome 6 at 42,629,467 bp
  • A to G, chromosome 6 at 108,405,529 bp
  • C to T, chromosome 6 at 129,119,788 bp
  • A to G, chromosome 7 at 6,708,420 bp
  • A to T, chromosome 7 at 26,266,921 bp
  • T to A, chromosome 7 at 41,648,584 bp
  • A to G, chromosome 7 at 61,549,532 bp
  • G to A, chromosome 7 at 144,506,264 bp
  • T to G, chromosome 8 at 5,640,130 bp
  • C to T, chromosome 8 at 28,694,676 bp
  • T to A, chromosome 8 at 63,345,855 bp
  • C to A, chromosome 8 at 122,864,348 bp
  • T to A, chromosome 9 at 37,418,560 bp
  • T to C, chromosome 9 at 97,483,079 bp
  • G to T, chromosome 10 at 78,450,307 bp
  • C to T, chromosome 10 at 99,107,841 bp
  • G to A, chromosome 11 at 97,669,500 bp
  • C to T, chromosome 11 at 99,792,872 bp
  • A to T, chromosome 11 at 99,949,468 bp
  • A to T, chromosome 11 at 107,296,267 bp
  • A to G, chromosome 12 at 59,050,308 bp
  • T to C, chromosome 12 at 72,659,481 bp
  • C to T, chromosome 12 at 83,555,647 bp
  • C to A, chromosome 12 at 84,649,474 bp
  • C to T, chromosome 13 at 3,576,357 bp
  • T to A, chromosome 15 at 98,226,761 bp
  • A to G, chromosome 17 at 29,850,554 bp
  • T to C, chromosome 17 at 35,380,441 bp
  • G to A, chromosome 18 at 37,685,595 bp
  • G to T, chromosome 18 at 42,053,924 bp
  • T to C, chromosome 19 at 5,468,458 bp
  • T to C, chromosome 19 at 6,277,221 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5076 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
042665-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.