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Strain Name:
C57BL/6J-MtgxR5540Btlr/Mmmh
Stock Number:
043098-MU
Citation ID:
RRID:MMRRC_043098-MU
Other Names:
R5540 (G1), C57BL/6J-MtgxR5540Btlr
Major Collection:

Strain Information

Apobec3
Name: apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3
Synonyms: Rfv-3, CEM15, Rfv3, Gm20117
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 80287
Homologene: 105420
Ptpn14
Name: protein tyrosine phosphatase, non-receptor type 14
Synonyms: PTP36, C130080N23Rik, OTTMUSG00000022087
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 19250
HGNC: HGNC:9647
Homologene: 3941
Kdm5b
Name: lysine demethylase 5B
Synonyms: PLU-1, 2010009J12Rik, Rb-Bp2, Plu1, 2210016I17Rik, D1Ertd202e, Jarid1b
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 75605
Homologene: 48448
Hdac5
Name: histone deacetylase 5
Synonyms: mHDA1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 15184
Homologene: 3995
Stk24
Name: serine/threonine kinase 24
Synonyms: 1810013H02Rik, STE20
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 223255
VEGA: 14
Homologene: 20793
Mtor
Name: mechanistic target of rapamycin kinase
Synonyms: FKBP-rapamycin-associated protein FRAP, 2610315D21Rik, RAPT1, RAFT1, flat, Frap1, mechanistic target of rapamycin (serine/threonine kinase)
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 56717
HGNC: HGNC:3942
Homologene: 3637
Eif4g2
Name: eukaryotic translation initiation factor 4, gamma 2
Synonyms: Nat1, DAP-5, Natm1, E130105L11Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 13690
HGNC: HGNC:3297
Homologene: 37477
Morc3
Name: microrchidia 3
Synonyms: 1110051N18Rik, D16Jhu32e, 1110051N18Rik, Zcwcc3
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 338467
Homologene: 32257
Wdr59
Name: WD repeat domain 59
Synonyms: 5430401O09Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 319481
Homologene: 38685
Washc4
Name: WASH complex subunit 4
Synonyms: A230046K03Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 319277
VEGA: 10
Homologene: 123926
Ambra1
Name: autophagy/beclin 1 regulator 1
Synonyms: 2310079H06Rik, D030051N19Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228361
Homologene: 18204
Arid1a
Name: AT-rich interaction domain 1A
Synonyms: Osa1, 1110030E03Rik, Smarcf1, BAF250a
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 93760
Homologene: 21216
Kif20b
Name: kinesin family member 20B
Synonyms: N-6 kinesin, C330014J10Rik, Kif20b, Mphosph1, 33cex, magoo
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 240641
VEGA: 19
HGNC: HGNC:7212
Homologene: 9418
Adgrl2
Name: adhesion G protein-coupled receptor L2
Synonyms: Lphh1, Lec1, Lphn2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99633
Homologene: 22712
Traf3ip1
Name: TRAF3 interacting protein 1
Synonyms: 3930402D05Rik, MIP-T3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 74019
Homologene: 22913
Fbxo38
Name: F-box protein 38
Synonyms: SP329, 6030410I24Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 107035
VEGA: 18
Homologene: 34526
Dyrk1a
Name: dual-specificity tyrosine phosphorylation regulated kinase 1a
Synonyms: Mnbh, Dyrk, D16Ertd493e, 2310043O08Rik, D16Ertd272e
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 13548
HGNC: HGNC:3091
Homologene: 55576
Dync1h1
Name: dynein cytoplasmic 1 heavy chain 1
Synonyms: MAP1C, dynein heavy chain, retrograde transport, Dnec1, Loa, 9930018I23Rik, Dnchc1, Swl
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 13424
HGNC: HGNC:2961
Homologene: 1053
Rnpc3
Name: RNA-binding region (RNP1, RRM) containing 3
Synonyms: C030014B17Rik, 2810441O16Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 67225
Homologene: 9746
Dmxl2
Name: Dmx-like 2
Synonyms: E130119P06Rik, 6430411K14Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235380
HGNC: HGNC:2938
Homologene: 41022
Scube1
Name: signal peptide, CUB domain, EGF-like 1
Synonyms: A630023E24Rik, 7330410C13Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 64706
Homologene: 11224
Crebrf
Name: CREB3 regulatory factor
Synonyms: A930001N09Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 77128
Homologene: 12672
Fndc3b
Name: fibronectin type III domain containing 3B
Synonyms: 1600019O04Rik, fad104
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 72007
Homologene: 11244
Nbeal2
Name: neurobeachin-like 2
Synonyms: 1110014F23Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235627
Homologene: 86422
Grik4
Name: glutamate receptor, ionotropic, kainate 4
Synonyms: KA1, 6330551K01Rik, GluRgamma1, KA-1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 110637
HGNC: HGNC:4582
Homologene: 81829
Celf2
Name: CUGBP, Elav-like family member 2
Synonyms: Napor-2, ETR-3, B230345P09Rik, Cugbp2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14007
HGNC: HGNC:2550
Homologene: 4783
Stk11
Name: serine/threonine kinase 11
Synonyms: Lkb1, Par-4
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 20869
Homologene: 393
Asph
Name: aspartate-beta-hydroxylase
Synonyms: cI-37, 2310005F16Rik, aspartyl beta-hydroxylase, calsequestrin-binding protein, Junctin, jumbug, BAH, 3110001L23Rik, junctate
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 65973
HGNC: HGNC:757
Homologene: 20910
Mis18bp1
Name: MIS18 binding protein 1
Synonyms: C79407
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217653
Homologene: 10147
Trhde
Name: TRH-degrading enzyme
Synonyms: 9330155P21Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 237553
Homologene: 75007
Akr1c18
Name: aldo-keto reductase family 1, member C18
Synonyms: 20alpha-HSD, 20alpha-hydroxysteroid dehydrogenase
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 105349
HGNC: HGNC:386
Homologene: 128661
Rusc2
Name: RUN and SH3 domain containing 2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100213
Homologene: 18967
Myh8
Name: myosin, heavy polypeptide 8, skeletal muscle, perinatal
Synonyms: MyHC-pn, Myhs-p, Myhsp, 4832426G23Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17885
HGNC: HGNC:7578
Homologene: 68256
Garin3
Name: golgi associated RAB2 interactor 3
Synonyms: OTTMUSG00000005491, Fam71b
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 432552
Homologene: 51067
Stab2
Name: stabilin 2
Synonyms: STAB-2, FEEL-2
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 192188
Homologene: 23022
Rnasel
Name: ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
Synonyms: 2-5A-dependent RNAase, E230029I04Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 24014
Homologene: 8040
Ephb3
Name: Eph receptor B3
Synonyms: Sek4, MDK5, HEK2, Etk2, Tyro6, Cek10
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 13845
HGNC: HGNC:3394
Homologene: 20938
Slc66a1
Name: solute carrier family 66 member 1
Synonyms: Pqlc2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 212555
Homologene: 56784
Flg
Name: filaggrin
Synonyms: profilaggrin, fillagrin, ft
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 14246
VEGA: 3
Actl7a
Name: actin-like 7a
Synonyms: Tact2, t-actin 2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 11470
HGNC: HGNC:161
Homologene: 7613
Aox1
Name: aldehyde oxidase 1
Synonyms: retinal oxidase, Aox-1, Aox-2, Aox2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 11761
HGNC: HGNC:553
Homologene: 68165
Phactr1
Name: phosphatase and actin regulator 1
Synonyms: Rpel1, 9630030F18Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218194
Homologene: 33597
Col6a5
Name: collagen, type VI, alpha 5
Synonyms: Col6a5, Gm7455
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 665033
Homologene: 122792
Alpk3
Name: alpha-kinase 3
Synonyms: Midori
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 116904
Homologene: 10813
Slc24a1
Name: solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 214111
VEGA: 9
Homologene: 3472
Shcbp1
Name: Shc SH2-domain binding protein 1
Synonyms: mPAL
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 20419
Homologene: 32123
Spag17
Name: sperm associated antigen 17
Synonyms: 4931427F14Rik, PF6
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 74362
Homologene: 52601
Myom1
Name: myomesin 1
Synonyms: skelemin, D430047A17Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 17929
VEGA: 17
HGNC: HGNC:7613
Homologene: 31196
Me1
Name: malic enzyme 1, NADP(+)-dependent, cytosolic
Synonyms: Mod-1, Mdh-1, D9Ertd267e, Mod1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 17436
HGNC: HGNC:6983
Homologene: 134785
Npc1l1
Name: NPC1 like intracellular cholesterol transporter 1
Synonyms: Niemann-Pick disease, type C1, 9130221N23Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237636
HGNC: HGNC:7898
Homologene: 56585
Hpx
Name: hemopexin
Synonyms: hx, Hpxn
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 15458
HGNC: HGNC:5171
Homologene: 511
Gm5828
Name: predicted gene 5828
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 545306
Adam26b
Name: a disintegrin and metallopeptidase domain 26B
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 382007
Homologene: 128363
Slc26a7
Name: solute carrier family 26, member 7
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 208890
Homologene: 13770
Pde6a
Name: phosphodiesterase 6A, cGMP-specific, rod, alpha
Synonyms: Pdea
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225600
HGNC: HGNC:8785
Homologene: 380
Or51f5
Name: olfactory receptor family 51 subfamily F member 5
Synonyms: GA_x6K02T2PBJ9-5491151-5492095, MOR14-2, Olfr561
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259096
Homologene: 133029
Tmem256
Name: transmembrane protein 256
Synonyms: 3110009M16Rik, 1810027O10Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 69186
Homologene: 45148
Serpinb6b
Name: serine (or cysteine) peptidase inhibitor, clade B, member 6b
Synonyms: Spi12, NK13, ovalbumin
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 20708
HGNC: HGNC:8950
Homologene: 22633
Or6c8b
Name: olfactory receptor family 6 subfamily C member 8B
Synonyms: GA_x6K02T2PULF-10732607-10731678, MOR115-4, Olfr765
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 544748
Homologene: 105186
Tmtc4
Name: transmembrane and tetratricopeptide repeat containing 4
Synonyms: 5730419O14Rik, 4930403J22Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 70551
Homologene: 32796
Chrnb1
Name: cholinergic receptor nicotinic beta 1 subunit
Synonyms: Achr-2, Acrb, AChR beta
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 11443
HGNC: HGNC:1961
Homologene: 594
Or5an9
Name: olfactory receptor family 5 subfamily AN member 9
Synonyms: GA_x6K02T2RE5P-2573738-2574676, MOR214-5, Olfr1431
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258409
Homologene: 115495
Vps16
Name: VSP16 CORVET/HOPS core subunit
Synonyms: 1810074M16Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 80743
Homologene: 7116
Or4d2
Name: olfactory receptor family 4 subfamily D member 2
Synonyms: GA_x6K02T2PAEV-9540823-9539888, MOR240-1, Olfr463
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258408
HGNC: HGNC:8294
Homologene: 64870
Or4c58
Name: olfactory receptor family 4 subfamily C member 58
Synonyms: IC3, MOR232-5, GA_x6K02T2Q125-51285881-51284976, Olfr48
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 18347
Homologene: 85936
Rsph3a
Name: radial spoke 3A homolog (Chlamydomonas)
Synonyms: 4930524H12Rik, 1700012G05Rik, Rshl2, Rshl2a
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 66832
VEGA: 17
Homologene: 12043
Paqr5
Name: progestin and adipoQ receptor family member V
Synonyms: 0610010I15Rik, mPRg
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 74090
Homologene: 9788
Map3k9
Name: mitogen-activated protein kinase kinase kinase 9
Synonyms: Mlk1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 338372
VEGA: 12
HGNC: HGNC:6861
Homologene: 76377
Akr1b10
Name: aldo-keto reductase family 1, member B10
Synonyms: 2310005E10Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 67861
Homologene: 128412
Tmem225
Name: transmembrane protein 225
Synonyms: 1700030E15Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 75667
VEGA: 9
Homologene: 52854
Cd300ld
Name: CD300 molecule like family member d
Synonyms: Clm5, MAIR-IV, 4732429D16Rik, Cd300ld1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217305
Homologene: 129719
Fpr-rs7
Name: formyl peptide receptor, related sequence 7
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 321021
HGNC: HGNC:3827
Wdr81
Name: WD repeat domain 81
Synonyms: shakey 5, MGC32441, nur5
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 192652
Homologene: 13983
Gfi1
Name: growth factor independent 1 transcription repressor
Synonyms: Pal-1, Pal1, Gfi-1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 14581
HGNC: HGNC:4237
Homologene: 3854
Tnfrsf4
Name: tumor necrosis factor receptor superfamily, member 4
Synonyms: CD134, ACT35, Ox40, Txgp1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 22163
Homologene: 2496
Vash1
Name: vasohibin 1
Synonyms: G630009D10Rik, D930046M13Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238328
Homologene: 8941
1700008O03Rik
Name: RIKEN cDNA 1700008O03 gene
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 69349
Homologene: 19260
Pcdha4
Name: protocadherin alpha 4
Synonyms: Cnr1, Crnr1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 12936
HGNC: HGNC:8670
Homologene: 130626
Gm5329
Name: predicted gene 5329
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 102633076
Pcdhga8
Name: protocadherin gamma subfamily A, 8
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93716
HGNC: HGNC:8706
Homologene: 57162
Gm3956
Name: predicted gene 3956
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 100042673
RP23-227D7.10
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
4930481A15Rik
Name: RIKEN cDNA 4930481A15 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 74931
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 16,769,292 bp
  • A to G, chromosome 1 at 58,104,410 bp
  • G to A, chromosome 1 at 91,501,315 bp
  • A to G, chromosome 1 at 134,631,241 bp
  • G to T, chromosome 1 at 153,755,144 bp
  • A to T, chromosome 1 at 189,846,364 bp
  • T to C, chromosome 2 at 6,553,932 bp
  • A to G, chromosome 2 at 89,844,667 bp
  • A to G, chromosome 2 at 91,773,025 bp
  • T to A, chromosome 2 at 130,442,385 bp
  • G to A, chromosome 3 at 27,501,502 bp
  • T to C, chromosome 3 at 93,277,616 bp
  • A to C, chromosome 3 at 100,056,272 bp
  • A to T, chromosome 3 at 113,628,341 bp
  • G to T, chromosome 3 at 148,827,518 bp
  • A to G, chromosome 3 at 148,837,562 bp
  • A to G, chromosome 4 at 9,635,906 bp
  • A to G, chromosome 4 at 14,506,621 bp
  • A to G, chromosome 4 at 43,423,975 bp
  • A to T, chromosome 4 at 56,744,388 bp
  • A to C, chromosome 4 at 133,680,454 bp
  • A to T, chromosome 4 at 139,300,344 bp
  • A to G, chromosome 4 at 148,454,708 bp
  • C to T, chromosome 4 at 156,013,923 bp
  • A to T, chromosome 5 at 87,486,056 bp
  • T to A, chromosome 5 at 107,720,125 bp
  • A to G, chromosome 6 at 34,394,112 bp
  • G to A, chromosome 7 at 8,667,574 bp
  • T to A, chromosome 7 at 31,972,444 bp
  • A to G, chromosome 7 at 44,362,947 bp
  • G to A, chromosome 7 at 81,095,436 bp
  • C to T, chromosome 7 at 102,774,929 bp
  • A to G, chromosome 7 at 105,591,912 bp
  • A to G, chromosome 7 at 111,080,860 bp
  • A to T, chromosome 8 at 4,744,529 bp
  • C to A, chromosome 8 at 43,521,617 bp
  • A to G, chromosome 8 at 111,485,184 bp
  • T to C, chromosome 9 at 40,149,385 bp
  • T to C, chromosome 9 at 42,520,947 bp
  • A to T, chromosome 9 at 54,393,857 bp
  • T to C, chromosome 9 at 61,963,788 bp
  • A to G, chromosome 9 at 64,948,581 bp
  • A to G, chromosome 9 at 86,679,873 bp
  • T to A, chromosome 9 at 105,862,776 bp
  • A to T, chromosome 9 at 110,631,733 bp
  • A to G, chromosome 10 at 80,126,049 bp
  • A to G, chromosome 10 at 83,573,793 bp
  • A to G, chromosome 10 at 86,848,125 bp
  • C to T, chromosome 10 at 92,972,608 bp
  • T to A, chromosome 10 at 114,800,592 bp
  • G to T, chromosome 10 at 129,046,495 bp
  • A to G, chromosome 11 at 6,214,546 bp
  • A to G, chromosome 11 at 46,404,888 bp
  • C to A, chromosome 11 at 67,286,440 bp
  • A to T, chromosome 11 at 69,795,650 bp
  • A to T, chromosome 11 at 69,839,336 bp
  • T to C, chromosome 11 at 75,449,070 bp
  • A to T, chromosome 11 at 85,911,168 bp
  • T to A, chromosome 11 at 87,893,685 bp
  • T to C, chromosome 11 at 102,198,971 bp
  • T to A, chromosome 11 at 114,987,405 bp
  • T to C, chromosome 12 at 65,148,746 bp
  • G to T, chromosome 12 at 81,772,813 bp
  • ACTGCTGCTGCTGCTGCTGC to ACTGCTGCTGCTGCTGC, chromosome 12 at 86,680,057 bp
  • A to G, chromosome 12 at 110,660,950 bp
  • A to G, chromosome 13 at 4,137,179 bp
  • A to T, chromosome 13 at 32,977,558 bp
  • G to T, chromosome 13 at 42,956,774 bp
  • T to C, chromosome 14 at 121,294,281 bp
  • A to G, chromosome 14 at 122,933,129 bp
  • T to A, chromosome 15 at 79,897,919 bp
  • T to G, chromosome 15 at 83,616,666 bp
  • T to A, chromosome 16 at 21,220,860 bp
  • T to A, chromosome 16 at 93,847,380 bp
  • T to G, chromosome 16 at 94,685,343 bp
  • T to G, chromosome 17 at 7,945,958 bp
  • C to T, chromosome 17 at 20,114,094 bp
  • A to G, chromosome 17 at 26,742,097 bp
  • G to A, chromosome 17 at 71,109,787 bp
  • A to G, chromosome 18 at 32,007,090 bp
  • C to A, chromosome 18 at 36,954,837 bp
  • G to A, chromosome 18 at 37,817,908 bp
  • T to G, chromosome 18 at 61,231,366 bp
  • A to G, chromosome 18 at 62,514,793 bp
  • T to C, chromosome 19 at 5,407,026 bp
  • T to A, chromosome 19 at 12,210,460 bp
  • A to T, chromosome 19 at 34,938,460 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5540 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
043098-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.