Strain Name:
C57BL/6J-MtgxR5867Btlr/Mmmh
Stock Number:
043233-MU
Citation ID:
RRID:MMRRC_043233-MU
Other Names:
R5867 (G1), C57BL/6J-MtgxR5867Btlr
Major Collection:

Gene Information

Pi4k2a
Name: phosphatidylinositol 4-kinase type 2 alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 84095
VEGA: 19
Homologene: 101681
Lamb1
Name: laminin B1
Synonyms: Lamb-1, D130003D08Rik, C80098, Lamb1-1, C81607
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 16777
HGNC: HGNC:6486
Homologene: 1722
Drd1
Name: dopamine receptor D1
Synonyms: D1 receptor, Drd-1, C030036C15Rik, Drd1a, Gpcr15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 13488
VEGA: 13
HGNC: HGNC:3020
Homologene: 30992
Cd36
Name: CD36 molecule
Synonyms: fatty acid translocase, FAT, Scarb3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 12491
HGNC: HGNC:1663
Homologene: 73871
Wdr82
Name: WD repeat domain containing 82
Synonyms: 9430077D24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 77305
Homologene: 42951
Kif20a
Name: kinesin family member 20A
Synonyms: Rabkinesin-6, Rab6kifl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 19348
VEGA: 18
HGNC: HGNC:9787
Homologene: 38093
Cyfip1
Name: cytoplasmic FMR1 interacting protein 1
Synonyms: Shyc, E030028J09Rik, l7Rl1, l(7)1Rl, pl-1, Sra-1, P140SRA-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 20430
Homologene: 22628
Vps13c
Name: vacuolar protein sorting 13C
Synonyms: C230055H22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 320528
VEGA: 9
Homologene: 41188
Ascc3
Name: activating signal cointegrator 1 complex subunit 3
Synonyms: Helic1, B630009I04Rik, ASC1p200
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 77987
VEGA: 10
Homologene: 4973
Zfhx3
Name: zinc finger homeobox 3
Synonyms: Sci, A230102L03Rik, Atbf1, WBP9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 11906
HGNC: HGNC:777
Homologene: 21366
Srebf2
Name: sterol regulatory element binding factor 2
Synonyms: SREBP-2, SREBP2gc, bHLHd2, SREBP2, nuc, lop13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 20788
VEGA: 15
Homologene: 20966
Pspc1
Name: paraspeckle protein 1
Synonyms: PSP1, 5730470C09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 66645
Homologene: 10108
Ubr7
Name: ubiquitin protein ligase E3 component n-recognin 7 (putative)
Synonyms: 5730410I19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 66622
VEGA: 12
Homologene: 11998
Ap1g1
Name: adaptor protein complex AP-1, gamma 1 subunit
Synonyms: gamma-adaptin, D8Ertd374e, Adtg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 11765
HGNC: HGNC:555
Homologene: 47995
Dclk2
Name: doublecortin-like kinase 2
Synonyms: 6330415M09Rik, Dcamkl2, Click-II
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 70762
Homologene: 69431
Tfrc
Name: transferrin receptor
Synonyms: Mtvr1, TfR1, Mtvr-1, CD71, Trfr, p90, 2610028K12Rik, E430033M20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 22042
Homologene: 2429
Vps50
Name: VPS50 EARP/GARPII complex subunit
Synonyms: 1700034M03Rik, Ccdc132, 8430415E05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 73288
Homologene: 11498
Ptprm
Name: protein tyrosine phosphatase, receptor type, M
Synonyms: RPTPmu
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 19274
VEGA: 17
HGNC: HGNC:9675
Homologene: 37694
Clmn
Name: calmin
Synonyms: 9330188N17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 94040
VEGA: 12
Homologene: 11683
Trpm2
Name: transient receptor potential cation channel, subfamily M, member 2
Synonyms: TRPC7, 9830168K16Rik, Trrp7, LTRPC2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 28240
Homologene: 20709
Cd209b
Name: CD209b antigen
Synonyms: 1810030I22Rik, mSIGNR1, SIGNR1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 69165
HGNC: HGNC:1641
Homologene: 84858
Pdk4
Name: pyruvate dehydrogenase kinase, isoenzyme 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 27273
HGNC: HGNC:8812
Homologene: 129720
Klhl6
Name: kelch-like 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 239743
Homologene: 15603
Camta2
Name: calmodulin binding transcription activator 2
Synonyms: Kiaa0909-hp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216874
Homologene: 9021
Ephb2
Name: Eph receptor B2
Synonyms: Prkm5, Sek3, Erk, Qek5, Cek5, Nuk, eteck, Drt, Tyro5, Hek5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 13844
HGNC: HGNC:3393
Homologene: 37925
Gm5134
Name: predicted gene 5134
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 333669
Homologene: 129891
Akip1
Name: A kinase (PRKA) interacting protein 1
Synonyms: ICRFP703N2430Q5.6, BCA3, D7H11orf17, D930014E17Rik, ORF27, ICRFP703B1614Q5.6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 57373
HGNC: HGNC:1170
Homologene: 10765
Cdh7
Name: cadherin 7, type 2
Synonyms: CDH7L1, 9330156F07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 241201
HGNC: HGNC:1766
Homologene: 68391
Vmn2r1
Name: vomeronasal 2, receptor 1
Synonyms: V2r83, EG56544
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 56544
Homologene: 84832
Ahnak
Name: AHNAK nucleoprotein (desmoyokin)
Synonyms: 2310047C17Rik, DY6, 1110004P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 66395
VEGA: 19
HGNC: HGNC:347
Homologene: 67425
Neu2
Name: neuraminidase 2
Synonyms: MBS, brain sialidase, MSS, MTS, cystolic sialidase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 23956
HGNC: HGNC:7759
Homologene: 3927
Lmod3
Name: leiomodin 3 (fetal)
Synonyms: 5430424A14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 320502
HGNC: HGNC:6649
Homologene: 28097
Mfsd6l
Name: major facilitator superfamily domain containing 6-like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 215723
Homologene: 17128
Gm16432
Name: predicted gene 16432
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Pkd1l2
Name: polycystic kidney disease 1 like 2
Synonyms: 1700126L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 76645
Homologene: 124481
Aldoart1
Name: aldolase 1 A, retrogene 1
Synonyms: 4921524E03Rik, Aldo1-ps2, Aldoa-ps2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 353204
Homologene: 128442
Mefv
Name: Mediterranean fever
Synonyms: pyrin, TRIM20, FMF, marenostrin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 54483
VEGA: 16
HGNC: HGNC:6998
Homologene: 32441
Ttc7
Name: tetratricopeptide repeat domain 7
Synonyms: fsn, hea, 1110035E02Rik, 1700007L07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 225049
Homologene: 12515
Gtsf2
Name: gametocyte specific factor 2
Synonyms: BC048502
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223927
VEGA: 15
Homologene: 77620
Fam43a
Name: family with sequence similarity 43, member A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224093
Homologene: 17800
Olfr1033
Name: olfactory receptor 1033
Synonyms: MOR199-2, GA_x6K02T2Q125-47516301-47517233
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258571
Homologene: 138314
Cyp2a5
Name: cytochrome P450, family 2, subfamily a, polypeptide 5
Synonyms: Coh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 13087
Homologene: 85917
Vmn1r42
Name: vomeronasal 1 receptor 42
Synonyms: V1ra6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 113848
Homologene: 130651
Cers4
Name: ceramide synthase 4
Synonyms: Trh1, CerS4, Lass4, 2900019C14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 67260
Homologene: 11582
Pdrg1
Name: p53 and DNA damage regulated 1
Synonyms: 1110004D19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 68559
Homologene: 12779
Zcchc3
Name: zinc finger, CCHC domain containing 3
Synonyms: 2810406K24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 67917
Homologene: 13214
Slc50a1
Name: solute carrier family 50 (sugar transporter), member 1
Synonyms: Rga, Rag1ap1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 19729
Homologene: 40647
Spata31d1d
Name: spermatogenesis associated 31 subfamily D, member 1D
Synonyms: Fam75d1d, 4932411G14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 238663
Homologene: 129932
Igkv4-77
Name: immunoglobulin kappa variable 4-77
Synonyms: Gm8732
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 667621
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to T, chromosome 1 at 87,596,756 bp
  • T to A, chromosome 1 at 110,048,851 bp
  • A to T, chromosome 1 at 178,111,236 bp
  • A to G, chromosome 2 at 86,041,451 bp
  • A to G, chromosome 2 at 152,414,524 bp
  • T to C, chromosome 2 at 153,014,055 bp
  • A to G, chromosome 3 at 64,104,569 bp
  • A to G, chromosome 3 at 86,791,859 bp
  • T to C, chromosome 3 at 89,269,280 bp
  • T to A, chromosome 4 at 72,852,533 bp
  • C to T, chromosome 4 at 136,675,422 bp
  • T to C, chromosome 5 at 17,785,735 bp
  • T to C, chromosome 6 at 3,536,965 bp
  • T to A, chromosome 6 at 5,487,452 bp
  • C to G, chromosome 6 at 69,111,088 bp
  • A to C, chromosome 6 at 89,844,779 bp
  • A to G, chromosome 6 at 97,248,002 bp
  • T to C, chromosome 7 at 26,842,958 bp
  • A to C, chromosome 7 at 55,926,313 bp
  • A to G, chromosome 7 at 109,707,477 bp
  • T to C, chromosome 8 at 3,924,246 bp
  • T to C, chromosome 8 at 4,521,318 bp
  • T to C, chromosome 8 at 108,793,446 bp
  • C to T, chromosome 8 at 109,818,982 bp
  • T to A, chromosome 8 at 117,055,011 bp
  • A to G, chromosome 9 at 67,982,622 bp
  • A to G, chromosome 9 at 106,185,304 bp
  • C to T, chromosome 10 at 50,842,183 bp
  • A to G, chromosome 10 at 76,008,616 bp
  • A to G, chromosome 10 at 77,932,409 bp
  • G to T, chromosome 11 at 68,557,210 bp
  • A to G, chromosome 11 at 70,670,152 bp
  • T to A, chromosome 12 at 31,298,955 bp
  • T to A, chromosome 12 at 102,761,494 bp
  • G to T, chromosome 12 at 104,781,755 bp
  • T to C, chromosome 13 at 54,054,163 bp
  • T to C, chromosome 13 at 59,727,240 bp
  • A to T, chromosome 14 at 56,762,041 bp
  • T to A, chromosome 15 at 82,169,786 bp
  • C to T, chromosome 15 at 103,439,636 bp
  • T to C, chromosome 16 at 3,715,933 bp
  • T to C, chromosome 16 at 19,982,820 bp
  • T to A, chromosome 16 at 30,601,459 bp
  • T to A, chromosome 16 at 32,620,412 bp
  • T to C, chromosome 17 at 67,045,981 bp
  • A to G, chromosome 17 at 87,322,472 bp
  • G to A, chromosome 18 at 34,632,415 bp
  • T to C, chromosome 19 at 9,010,052 bp
  • T to C, chromosome 19 at 42,105,485 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5867 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043233-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.