Strain Name:
C57BL/6J-MtgxR5670Btlr/Mmmh
Stock Number:
043313-MU
Citation ID:
RRID:MMRRC_043313-MU
Other Names:
R5670 (G1)
Major Collection:

Gene Information

Arhgef10
Name: Rho guanine nucleotide exchange factor (GEF) 10
Synonyms: 6430549H08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234094
Homologene: 22827
Vps54
Name: VPS54 GARP complex subunit
Synonyms: Vps54l, 5330404P15Rik, mSLP8, wr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 245944
Homologene: 5605
Slc4a2
Name: solute carrier family 4 (anion exchanger), member 2
Synonyms: B3RP, Ae2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 20535
Homologene: 128699
Fzd6
Name: frizzled class receptor 6
Synonyms: Fz6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 14368
VEGA: 15
HGNC: HGNC:4044
Homologene: 2617
Rab3gap2
Name: RAB3 GTPase activating protein subunit 2
Synonyms: 1110059F07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 98732
Homologene: 40842
Dip2b
Name: disco interacting protein 2 homolog B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239667
Homologene: 72227
Trim24
Name: tripartite motif-containing 24
Synonyms: Tif1a, D430004I05Rik, A130082H20Rik, TIF1alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 21848
Homologene: 20830
Nfe2l2
Name: nuclear factor, erythroid derived 2, like 2
Synonyms: Nrf2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18024
HGNC: HGNC:7782
Homologene: 2412
Prss16
Name: protease, serine 16 (thymus)
Synonyms: TSSP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 54373
HGNC: HGNC:9480
Homologene: 38106
Phldb1
Name: pleckstrin homology like domain, family B, member 1
Synonyms: LL5A, D330037A14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 102693
Homologene: 15903
Rnd2
Name: Rho family GTPase 2
Synonyms: Arhn, Rohn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 11858
Homologene: 21123
Btla
Name: B and T lymphocyte associated
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 208154
Homologene: 52233
Chd2
Name: chromodomain helicase DNA binding protein 2
Synonyms: 2810040A01Rik, 2810013C04Rik, 5630401D06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 244059
HGNC: HGNC:1917
Homologene: 37462
Steap2
Name: six transmembrane epithelial antigen of prostate 2
Synonyms: 4921538B17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 74051
Homologene: 17682
Copg1
Name: coatomer protein complex, subunit gamma 1
Synonyms: D6Ertd71e, D6Wsu16e, Copg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 54161
HGNC: HGNC:2236
Homologene: 56745
Ilkap
Name: integrin-linked kinase-associated serine/threonine phosphatase 2C
Synonyms: 1600009O09Rik, PP2C-DELTA, 0710007A14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 67444
Homologene: 31525
Pi16
Name: peptidase inhibitor 16
Synonyms: 1200009H11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 74116
Homologene: 134317
Pdgfra
Name: platelet derived growth factor receptor, alpha polypeptide
Synonyms: CD140a, Pdgfr-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 18595
HGNC: HGNC:8803
Homologene: 31361
Col4a4
Name: collagen, type IV, alpha 4
Synonyms: [a]4(IV), E130010M05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12829
HGNC: HGNC:2206
Homologene: 20071
Rgs21
Name: regulator of G-protein signalling 21
Synonyms: EG624910
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 624910
Homologene: 82452
Bmper
Name: BMP-binding endothelial regulator
Synonyms: Cv2, 3110056H04Rik, CV-2, Crim3, crossveinless-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 73230
VEGA: 9
Homologene: 12494
Tespa1
Name: thymocyte expressed, positive selection associated 1
Synonyms: A430001F24Rik, 5830405N20Rik, Itprid3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 67596
VEGA: 10
Homologene: 106645
Syne2
Name: spectrin repeat containing, nuclear envelope 2
Synonyms: nesprin-2, syne-2, D12Ertd777e, 6820443O06Rik, Nesp2g, Cpfl8, diminished cone electroretinogram, dice
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 319565
Homologene: 56700
Mttp
Name: microsomal triglyceride transfer protein
Synonyms: MTP, 1810043K16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 17777
HGNC: HGNC:7467
Homologene: 212
Zfp648
Name: zinc finger protein 648
Synonyms: LOC207678, Gm10178
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 100503355
Homologene: 18996
Glce
Name: glucuronyl C5-epimerase
Synonyms: heparan sulfate-glucuronic acid C5-epimerase, Hsepi, C130034A12Rik, 1110017N23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 93683
Homologene: 14111
Rnf213
Name: ring finger protein 213
Synonyms: D11Ertd759e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 672511
Homologene: 45439
Fer1l6
Name: fer-1-like 6 (C. elegans)
Synonyms: EG631797
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 631797
Homologene: 53396
Nwd1
Name: NACHT and WD repeat domain containing 1
Synonyms: A230063L24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 319555
Homologene: 72261
Sptbn5
Name: spectrin beta, non-erythrocytic 5
Synonyms: EG640524, Spnb5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 640524
Homologene: 41150
Dscam
Name: DS cell adhesion molecule
Synonyms: 4932410A21Rik, Down syndrome cell adhesion molecule
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 13508
HGNC: HGNC:3039
Homologene: 74393
Vmn2r10
Name: vomeronasal 2, receptor 10
Synonyms: VR16, V2r16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 22307
Homologene: 129606
Olfr173
Name: olfactory receptor 173
Synonyms: GA_x54KRFPKG5P-54960233-54959268, MOR184-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 259002
HGNC: HGNC:8349
Homologene: 45084
Ddb2
Name: damage specific DNA binding protein 2
Synonyms: p48, 2610043A19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 107986
HGNC: HGNC:2718
Homologene: 83
Igkv8-18
Name: immunoglobulin kappa variable 8-18
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 667859
Cap2
Name: CAP, adenylate cyclase-associated protein, 2 (yeast)
Synonyms: 2810452G09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 67252
Homologene: 101397
Gm4787
Name: predicted gene 4787
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 214321
Homologene: 86950
Lpin3
Name: lipin 3
Synonyms: 9130206L11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 64899
Homologene: 84844
Tpte
Name: transmembrane phosphatase with tensin homology
Synonyms: Pten2, Vsp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234129
Homologene: 50411
Tm4sf1
Name: transmembrane 4 superfamily member 1
Synonyms: 12A8 target antigen, L6 antigen, L6, M3s1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 17112
Homologene: 7409
Tmprss13
Name: transmembrane protease, serine 13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 214531
Homologene: 12936
Ahsg
Name: alpha-2-HS-glycoprotein
Synonyms: fetuin-A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 11625
VEGA: 16
HGNC: HGNC:349
Homologene: 1225
Olfr1271
Name: olfactory receptor 1271
Synonyms: GA_x6K02T2Q125-51620802-51619885, MOR227-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258789
Tlx2
Name: T cell leukemia, homeobox 2
Synonyms: Enx, Ncx1, Hox11l1, NCX, Hox11L.1, Tlx1l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 21909
HGNC: HGNC:5057
Homologene: 7575
Olfr1389
Name: olfactory receptor 1389
Synonyms: GA_x6K02T2QP88-6004387-6003452, MOR256-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 259069
Homologene: 86690
Dtd2
Name: D-tyrosyl-tRNA deacylase 2
Synonyms: 4930578F06Rik, B830049N13Rik, 6530401N04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 328092
Homologene: 12634
Pramel29
Name: PRAME like 29
Synonyms: C87977
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 97187
Homologene: 103830
Nkain4
Name: Na+/K+ transporting ATPase interacting 4
Synonyms: C030019F02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 58237
Homologene: 10978
Olfr365
Name: olfactory receptor 365
Synonyms: GA_x6K02T2NLDC-33885305-33886243, MOR138-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258656
Homologene: 74156
Ikzf2
Name: IKAROS family zinc finger 2
Synonyms: Helios, Zfpn1a2, A730095J18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 22779
Homologene: 22659
4930524J08Rik
Name: RIKEN cDNA 4930524J08 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Vwa1
Name: von Willebrand factor A domain containing 1
Synonyms: WARP, 4932416A11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 246228
Homologene: 11270
Plekha2
Name: pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
Synonyms: TAPP2, 6430512N22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 83436
Homologene: 41822
Mfsd8
Name: major facilitator superfamily domain containing 8
Synonyms: 2810423E13Rik, Cln7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 72175
Homologene: 115814
Ndufaf4
Name: NADH:ubiquinone oxidoreductase complex assembly factor 4
Synonyms: 3000003G13Rik, 1110007M04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 68493
Homologene: 40928
Gm38100
Name: predicted gene, 38100
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 69,577,900 bp
  • A to G, chromosome 1 at 82,485,579 bp
  • T to C, chromosome 1 at 91,391,141 bp
  • A to G, chromosome 1 at 144,536,942 bp
  • C to A, chromosome 1 at 154,204,217 bp
  • C to T, chromosome 1 at 175,921,613 bp
  • C to T, chromosome 1 at 185,221,899 bp
  • T to A, chromosome 1 at 185,277,205 bp
  • T to A, chromosome 2 at 37,201,994 bp
  • T to C, chromosome 2 at 75,677,118 bp
  • T to C, chromosome 2 at 90,265,964 bp
  • C to T, chromosome 2 at 91,212,581 bp
  • C to G, chromosome 2 at 120,085,567 bp
  • A to G, chromosome 2 at 160,897,330 bp
  • A to G, chromosome 2 at 180,943,202 bp
  • A to T, chromosome 3 at 40,822,049 bp
  • A to T, chromosome 3 at 57,293,087 bp
  • A to T, chromosome 3 at 138,125,113 bp
  • A to T, chromosome 4 at 24,898,636 bp
  • A to G, chromosome 4 at 144,209,622 bp
  • A to G, chromosome 4 at 155,774,465 bp
  • C to T, chromosome 5 at 5,673,681 bp
  • G to T, chromosome 5 at 24,434,838 bp
  • T to C, chromosome 5 at 75,173,495 bp
  • T to C, chromosome 5 at 99,979,209 bp
  • A to T, chromosome 5 at 108,999,044 bp
  • T to C, chromosome 6 at 37,965,601 bp
  • C to T, chromosome 6 at 70,356,149 bp
  • G to A, chromosome 6 at 83,069,826 bp
  • C to T, chromosome 6 at 87,912,235 bp
  • A to T, chromosome 7 at 73,441,717 bp
  • T to C, chromosome 8 at 14,954,774 bp
  • C to T, chromosome 8 at 22,327,748 bp
  • C to A, chromosome 8 at 25,059,238 bp
  • T to A, chromosome 8 at 72,693,117 bp
  • T to A, chromosome 9 at 23,473,463 bp
  • T to C, chromosome 9 at 44,715,781 bp
  • A to G, chromosome 9 at 45,344,955 bp
  • A to G, chromosome 9 at 62,060,511 bp
  • T to C, chromosome 10 at 130,354,755 bp
  • T to A, chromosome 11 at 21,264,864 bp
  • T to G, chromosome 11 at 49,431,208 bp
  • C to T, chromosome 11 at 101,468,999 bp
  • A to G, chromosome 11 at 119,434,686 bp
  • T to A, chromosome 12 at 51,999,860 bp
  • G to A, chromosome 12 at 75,950,959 bp
  • G to A, chromosome 12 at 81,378,031 bp
  • C to T, chromosome 13 at 22,003,051 bp
  • T to A, chromosome 13 at 46,531,083 bp
  • A to T, chromosome 15 at 39,031,115 bp
  • C to T, chromosome 15 at 58,622,482 bp
  • A to G, chromosome 15 at 100,190,104 bp
  • T to A, chromosome 16 at 22,898,163 bp
  • A to T, chromosome 16 at 45,250,419 bp
  • G to A, chromosome 16 at 58,797,061 bp
  • G to A, chromosome 16 at 96,718,164 bp
  • C to T, chromosome 17 at 29,326,896 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5670 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
043313-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.