Strain Name:
C57BL/6J-MtgxR6017Btlr
Stock Number:
044191-MU
Citation ID:
RRID:MMRRC_044191-MU
Other Names:
R6017 (G1)
Major Collection:

Gene Information

Ppp1r9a
Name: protein phosphatase 1, regulatory subunit 9A
Synonyms: neurabin-I, 4930518N04Rik, NRB, Neurabin I, 2810430P21Rik, A230094E16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243725
Homologene: 14247
Cdc42ep4
Name: CDC42 effector protein (Rho GTPase binding) 4
Synonyms: 1500041M20Rik, Borg4, CEP4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 56699
Homologene: 8110
Oxsr1
Name: oxidative-stress responsive 1
Synonyms: Osr1, 2210022N24Rik, 2810422B09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 108737
HGNC: HGNC:8508
Homologene: 31288
Kcnj1
Name: potassium inwardly-rectifying channel, subfamily J, member 1
Synonyms: ROMK, Kir1.1, ROMK-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 56379
VEGA: 9
HGNC: HGNC:6255
Homologene: 56764
Stk24
Name: serine/threonine kinase 24
Synonyms: 1810013H02Rik, STE20
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 223255
VEGA: 14
Homologene: 20793
Vps35l
Name: VPS35 endosomal protein sorting factor like
Synonyms: Vsp35l, 9030624J02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 71517
Homologene: 10659
Wdfy3
Name: WD repeat and FYVE domain containing 3
Synonyms: 2610509D04Rik, Bwf1, D5Ertd66e, Alfy, Ggtb3, Bchs
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 72145
Homologene: 22855
Map4
Name: microtubule-associated protein 4
Synonyms: MAP 4, Mtap4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 17758
HGNC: HGNC:6862
Homologene: 1780
Copb1
Name: coatomer protein complex, subunit beta 1
Synonyms: 2610019B04Rik, Copb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 70349
HGNC: HGNC:2231
Homologene: 5664
Myo18a
Name: myosin XVIIIA
Synonyms: MyoPDZ
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 360013
Homologene: 7977
Trrap
Name: transformation/transcription domain-associated protein
Synonyms: transactivation/transformation-domain associated protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100683
Homologene: 39246
Arpc2
Name: actin related protein 2/3 complex, subunit 2
Synonyms: p34-Arc, 2210023N03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 76709
HGNC: HGNC:705
Homologene: 4187
Epha8
Name: Eph receptor A8
Synonyms: Hek3, EphA8, Eek
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 13842
HGNC: HGNC:3391
Homologene: 22436
Nf2
Name: neurofibromin 2
Synonyms: moesin-ezrin-radixin-like protein, schwannomin, merlin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18016
HGNC: HGNC:7773
Homologene: 2180
Scfd1
Name: Sec1 family domain containing 1
Synonyms: 3110021P21Rik, RA410, STXBP1L2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 76983
VEGA: 12
Homologene: 5650
B3galt5
Name: UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5
Synonyms: b3Galt-V, 1190002B21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 93961
HGNC: HGNC:920
Homologene: 13230
Crebrf
Name: CREB3 regulatory factor
Synonyms: A930001N09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 77128
Homologene: 12672
Bod1l
Name: biorientation of chromosomes in cell division 1-like
Synonyms: A230054D04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 665775
Homologene: 45109
Zfp457
Name: zinc finger protein 457
Synonyms: Rslcan-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 431706
Homologene: 75311
Hgfac
Name: hepatocyte growth factor activator
Synonyms: HGFA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 54426
HGNC: HGNC:4894
Homologene: 1170
Cacfd1
Name: calcium channel flower domain containing 1
Synonyms: mFwe, 5930434B04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 381356
HGNC: HGNC:1365
Homologene: 41182
Cldn1
Name: claudin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 12737
HGNC: HGNC:2032
Homologene: 9620
Hepacam2
Name: HEPACAM family member 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 101202
Homologene: 18724
Eml2
Name: echinoderm microtubule associated protein like 2
Synonyms: 1600029N02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 72205
Homologene: 8125
Dpys
Name: dihydropyrimidinase
Synonyms: DHPase, 1300004I01Rik, 1200017I10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 64705
HGNC: HGNC:3013
Homologene: 20359
Ddx11
Name: DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
Synonyms: 4732462I11Rik, essa15a, KRG2, CHL1, CHLR1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 320209
VEGA: 17
HGNC: HGNC:2736
Homologene: 68973
Skor2
Name: SKI family transcriptional corepressor 2
Synonyms: Fussel18, Gm7348, Corl2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 664805
VEGA: 18
Homologene: 64797
Spata31d1c
Name: spermatogenesis associated 31 subfamily D, member 1C
Synonyms: 4932441B19Rik, Fam75d1c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 238683
VEGA: 13
Ush2a
Name: usherin
Synonyms: MUSH2A, A930037M10Rik, LOC381317, Ush2a, Ushrn, A930011D15Rik, LOC269160
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 22283
Homologene: 66151
Cntnap5c
Name: contactin associated protein-like 5C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 620292
VEGA: 17
Homologene: 128806
Adgrv1
Name: adhesion G protein-coupled receptor V1
Synonyms: Gpr98, Mgr1, Mass1, VLGR1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 110789
Homologene: 19815
Cyp1a2
Name: cytochrome P450, family 1, subfamily a, polypeptide 2
Synonyms: P450-3, CP12, aromatic compound inducible
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 13077
VEGA: 9
HGNC: HGNC:2596
Homologene: 68082
Ephb3
Name: Eph receptor B3
Synonyms: MDK5, HEK2, Etk2, Sek4, Cek10, Tyro6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 13845
HGNC: HGNC:3394
Homologene: 20938
Fbxo44
Name: F-box protein 44
Synonyms: Fbx6a, FBX30, Fbxo6a, FBG3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230903
Homologene: 13232
Csmd3
Name: CUB and Sushi multiple domains 3
Synonyms: 4930500N14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239420
Homologene: 65982
Spata6
Name: spermatogenesis associated 6
Synonyms: Hash, KRP, 1700062C23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 67946
Homologene: 10410
Stab1
Name: stabilin 1
Synonyms: MS-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 192187
Homologene: 9035
Slc8a1
Name: solute carrier family 8 (sodium/calcium exchanger), member 1
Synonyms: Ncx1, D930008O12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 20541
VEGA: 17
Homologene: 69090
Tyro3
Name: TYRO3 protein tyrosine kinase 3
Synonyms: Sky, Brt, Sky, Dtk, Tif, Etk-2, Rse
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22174
Homologene: 4585
Adgb
Name: androglobin
Synonyms: 9130014G24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 215772
Homologene: 100289
Vmn2r105
Name: vomeronasal 2, receptor 105
Synonyms: EG627743
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 627743
Homologene: 129680
Cyp4a12a
Name: cytochrome P450, family 4, subfamily a, polypeptide 12a
Synonyms: Cyp4a12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 277753
Homologene: 134044
Kctd16
Name: potassium channel tetramerisation domain containing 16
Synonyms: 2900055J20Rik, 4930434H12Rik, LOC383347
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 73001
VEGA: 18
Homologene: 44779
Ptk6
Name: PTK6 protein tyrosine kinase 6
Synonyms: Sik, Tksk
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20459
HGNC: HGNC:9617
Homologene: 68494
Slc2a7
Name: solute carrier family 2 (facilitated glucose transporter), member 7
Synonyms: OTTMUSG00000010396
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 435818
Homologene: 72470
Cyp2d26
Name: cytochrome P450, family 2, subfamily d, polypeptide 26
Synonyms: 1300006E06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 76279
VEGA: 15
Homologene: 130660
Gss
Name: glutathione synthetase
Synonyms: GS-A/GS-B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14854
HGNC: HGNC:4624
Homologene: 148
Ip6k2
Name: inositol hexaphosphate kinase 2
Synonyms: Ihpk2, 1500005N04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 76500
Homologene: 56929
Kif28
Name: kinesin family member 28
Synonyms: Gm1305, LOC383592
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 383592
Homologene: 130945
Mpp4
Name: membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
Synonyms: DLG6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227157
Homologene: 23296
Dsn1
Name: DSN1 homolog, MIS12 kinetochore complex component
Synonyms: 1700022L09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 66934
Homologene: 49806
Olfr855
Name: olfactory receptor 855
Synonyms: MOR148-1, GA_x6K02T2PVTD-13330461-13331399
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258517
Homologene: 74176
Lce1e
Name: late cornified envelope 1E
Synonyms: 1110031B11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 68694
Irx5
Name: Iroquois homeobox 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 54352
Homologene: 38105
Hepacam
Name: hepatocyte cell adhesion molecule
Synonyms: 2900042E01Rik, Glialcam
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 72927
Homologene: 17652
Kcnf1
Name: potassium voltage-gated channel, subfamily F, member 1
Synonyms: LOC382571
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 382571
HGNC: HGNC:6246
Homologene: 124236
Zfp758
Name: zinc finger protein 758
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224598
Homologene: 138293
Mettl17
Name: methyltransferase like 17
Synonyms: 2310032K15Rik, Mett11d1, D14Ertd209e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 52535
Homologene: 11226
Olfr147
Name: olfactory receptor 147
Synonyms: MOR164-1, M3, GA_x6K02T2PVTD-32098059-32099003
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258869
VEGA: 9
Homologene: 128279
Plekhg2
Name: pleckstrin homology domain containing, family G (with RhoGef domain) member 2
Synonyms: Clg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 101497
Homologene: 16341
Kcnk12
Name: potassium channel, subfamily K, member 12
Synonyms: mntk1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 210741
VEGA: 17
HGNC: HGNC:6274
Homologene: 11107
Serpina1b
Name: serine (or cysteine) preptidase inhibitor, clade A, member 1B
Synonyms: Spi1-2, D12Ucla2, PI2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 20701
HGNC: HGNC:8941
Homologene: 20103
Uts2b
Name: urotensin 2B
Synonyms: Urp, Uts2d
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224065
Homologene: 52352
Cmtm1
Name: CKLF-like MARVEL transmembrane domain containing 1
Synonyms: CHLFH1a, Cklfsf1, CKLFH1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 100504164
Homologene: 134399
Gm7347
Name: predicted gene 7347
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 664804
Homologene: 69402
Gm13102
Name: predicted gene 13102
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100041077
Homologene: 133722
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 59,121,359 bp
  • C to A, chromosome 1 at 74,262,486 bp
  • T to A, chromosome 1 at 179,699,453 bp
  • T to C, chromosome 1 at 188,957,514 bp
  • T to G, chromosome 2 at 27,013,428 bp
  • T to A, chromosome 2 at 119,816,666 bp
  • C to A, chromosome 2 at 155,587,465 bp
  • C to A, chromosome 2 at 156,996,242 bp
  • C to T, chromosome 2 at 181,195,812 bp
  • T to A, chromosome 3 at 92,707,933 bp
  • C to A, chromosome 4 at 111,774,827 bp
  • T to A, chromosome 4 at 115,326,279 bp
  • G to T, chromosome 4 at 136,931,743 bp
  • T to C, chromosome 4 at 144,109,237 bp
  • G to T, chromosome 4 at 148,158,553 bp
  • T to C, chromosome 4 at 150,165,172 bp
  • T to C, chromosome 5 at 26,057,278 bp
  • T to C, chromosome 5 at 35,044,395 bp
  • A to T, chromosome 5 at 41,818,760 bp
  • T to C, chromosome 5 at 101,851,359 bp
  • A to G, chromosome 5 at 144,844,241 bp
  • C to A, chromosome 6 at 3,483,332 bp
  • T to A, chromosome 6 at 4,906,363 bp
  • G to A, chromosome 7 at 19,201,163 bp
  • G to A, chromosome 7 at 28,362,884 bp
  • T to C, chromosome 7 at 114,236,797 bp
  • T to A, chromosome 7 at 118,809,921 bp
  • T to A, chromosome 8 at 92,358,250 bp
  • C to A, chromosome 8 at 104,310,951 bp
  • T to C, chromosome 9 at 19,585,434 bp
  • A to T, chromosome 9 at 32,394,104 bp
  • A to G, chromosome 9 at 37,380,760 bp
  • A to T, chromosome 9 at 38,403,620 bp
  • T to C, chromosome 9 at 57,681,030 bp
  • G to A, chromosome 9 at 108,797,267 bp
  • T to C, chromosome 9 at 110,034,619 bp
  • A to G, chromosome 9 at 119,264,777 bp
  • T to C, chromosome 10 at 10,450,036 bp
  • A to T, chromosome 11 at 4,816,137 bp
  • A to G, chromosome 11 at 77,841,523 bp
  • A to T, chromosome 11 at 113,729,366 bp
  • T to C, chromosome 12 at 17,175,081 bp
  • T to C, chromosome 12 at 51,445,678 bp
  • A to G, chromosome 12 at 103,729,272 bp
  • A to G, chromosome 13 at 65,035,079 bp
  • G to A, chromosome 13 at 67,293,699 bp
  • A to T, chromosome 13 at 81,397,423 bp
  • C to T, chromosome 14 at 31,141,544 bp
  • C to T, chromosome 14 at 51,891,617 bp
  • C to T, chromosome 14 at 121,302,245 bp
  • T to A, chromosome 15 at 39,846,718 bp
  • C to A, chromosome 15 at 48,314,012 bp
  • A to G, chromosome 15 at 82,790,573 bp
  • T to C, chromosome 16 at 21,222,031 bp
  • G to T, chromosome 16 at 26,363,219 bp
  • T to C, chromosome 16 at 27,361,043 bp
  • A to G, chromosome 16 at 96,315,184 bp
  • T to A, chromosome 17 at 20,208,627 bp
  • A to G, chromosome 17 at 22,373,731 bp
  • A to C, chromosome 17 at 26,757,849 bp
  • A to T, chromosome 17 at 58,104,698 bp
  • A to G, chromosome 17 at 66,130,017 bp
  • A to G, chromosome 17 at 81,648,254 bp
  • T to C, chromosome 17 at 87,746,736 bp
  • T to C, chromosome 18 at 40,258,943 bp
  • T to A, chromosome 18 at 76,858,927 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6017 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044191-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.