Strain Name:
C57BL/6J-MtgxR6041Btlr
Stock Number:
044209-MU
Citation ID:
RRID:MMRRC_044209-MU
Other Names:
R6041 (G1)
Major Collection:

Gene Information

Pax6
Name: paired box 6
Synonyms: Pax-6, AEY11, 1500038E17Rik, Dickie's small eye, Dey, Gsfaey11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18508
HGNC: HGNC:8620
Homologene: 1212
Psen2
Name: presenilin 2
Synonyms: PS-2, Ad4h, ALG-3, PS2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 19165
HGNC: HGNC:9509
Homologene: 386
Macf1
Name: microtubule-actin crosslinking factor 1
Synonyms: Acf7, trabeculin alpha, Aclp7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 11426
Homologene: 136191
Tet1
Name: tet methylcytosine dioxygenase 1
Synonyms: BB001228, 2510010B09Rik, Cxxc6, D10Ertd17e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 52463
Homologene: 12735
Sipa1l1
Name: signal-induced proliferation-associated 1 like 1
Synonyms: Spar, 4931426N11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 217692
VEGA: 12
Homologene: 9189
Npy5r
Name: neuropeptide Y receptor Y5
Synonyms: Y5R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 18168
HGNC: HGNC:7958
Homologene: 21241
Scrib
Name: scribbled planar cell polarity
Synonyms: Crc, Scrb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 105782
Homologene: 44228
Rapgef2
Name: Rap guanine nucleotide exchange factor (GEF) 2
Synonyms: 5830453M24Rik, nRapGEP, CNRasGEF, RA-GEF-1, Pdzgef1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 76089
Homologene: 35477
Vipr2
Name: vasoactive intestinal peptide receptor 2
Synonyms: VIP receptor subtype 2, VPAC2R, VPAC2, Vip2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 22355
Homologene: 2540
Dgkh
Name: diacylglycerol kinase, eta
Synonyms: 5930402B05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 380921
VEGA: 14
HGNC: HGNC:2854
Homologene: 99373
Pi4ka
Name: phosphatidylinositol 4-kinase alpha
Synonyms: Pik4ca
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224020
HGNC: HGNC:8983
Homologene: 11171
Tbc1d23
Name: TBC1 domain family, member 23
Synonyms: D030022P07Rik, 4930451A13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 67581
VEGA: 16
Homologene: 10126
Senp1
Name: SUMO1/sentrin specific peptidase 1
Synonyms: 2310046A20Rik, D15Ertd528e, E330036L07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223870
Homologene: 8731
F2rl2
Name: coagulation factor II (thrombin) receptor-like 2
Synonyms: PAR-3, PAR3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 14064
HGNC: HGNC:3539
Homologene: 36151
Hexa
Name: hexosaminidase A
Synonyms: Hex-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 15211
VEGA: 9
HGNC: HGNC:4878
Homologene: 20146
Rad17
Name: RAD17 checkpoint clamp loader component
Synonyms: MmRad24, 9430035O09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 19356
VEGA: 13
HGNC: HGNC:9807
Homologene: 32117
Pmf1
Name: polyamine-modulated factor 1
Synonyms: 2600009M07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 67037
Homologene: 5224
Gfm2
Name: G elongation factor, mitochondrial 2
Synonyms: EFG2, 6530419G12Rik, MST027, A930009M04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 320806
Homologene: 6238
Dmxl2
Name: Dmx-like 2
Synonyms: 6430411K14Rik, E130119P06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235380
HGNC: HGNC:2938
Homologene: 41022
Trak1
Name: trafficking protein, kinesin binding 1
Synonyms: hyrt, 2310001H13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 67095
Homologene: 25103
Scn10a
Name: sodium channel, voltage-gated, type X, alpha
Synonyms: Nav1.8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 20264
VEGA: 9
Homologene: 21300
Casc3
Name: cancer susceptibility candidate 3
Synonyms: Mln51, Btz
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 192160
Homologene: 7208
Leng8
Name: leukocyte receptor cluster (LRC) member 8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 232798
Homologene: 13612
Calcoco1
Name: calcium binding and coiled coil domain 1
Synonyms: Gcap11, CoCoA, 1810009B06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 67488
Homologene: 10845
Ptprs
Name: protein tyrosine phosphatase, receptor type, S
Synonyms: PTP-NU3, RPTPsigma, Ptpt9, PTPsigma
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 19280
HGNC: HGNC:9681
Homologene: 20626
Nipbl
Name: NIPBL cohesin loading factor
Synonyms: 4933421G18Rik, 4921518A06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 71175
VEGA: 15
Homologene: 15850
Dnajb11
Name: DnaJ heat shock protein family (Hsp40) member B11
Synonyms: ABBP-2, 1810031F23Rik, Dj9, ERdj3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 67838
Homologene: 9464
Clmn
Name: calmin
Synonyms: 9330188N17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 94040
VEGA: 12
Homologene: 11683
Smcr8
Name: Smith-Magenis syndrome chromosome region, candidate 8 homolog (human)
Synonyms: D030073L15Rik, 2310076G09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237782
Homologene: 16989
Rbp3
Name: retinol binding protein 3, interstitial
Synonyms: Irbp, Rbp-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 19661
VEGA: 14
HGNC: HGNC:9921
Homologene: 9261
Abca3
Name: ATP-binding cassette, sub-family A (ABC1), member 3
Synonyms: ABC-C, Abc3, 1810036E22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 27410
HGNC: HGNC:33
Homologene: 37437
Myof
Name: myoferlin
Synonyms: 2310051D19Rik, E030042N20Rik, Fer1l3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 226101
VEGA: 19
HGNC: HGNC:3656
Homologene: 40882
Myh13
Name: myosin, heavy polypeptide 13, skeletal muscle
Synonyms: extraocular myosin, EO Myosin, MyHC-eo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 544791
HGNC: HGNC:7571
Homologene: 55780
Cacna1d
Name: calcium channel, voltage-dependent, L type, alpha 1D subunit
Synonyms: 8430418G19Rik, Cchl1a, Cacnl1a2, C79217, Cchl1a2, D-LTCC, Cav1.3alpha1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 12289
VEGA: 14
HGNC: HGNC:1391
Homologene: 578
Megf10
Name: multiple EGF-like-domains 10
Synonyms: LOC240312, 3000002B06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 70417
Homologene: 23771
Zfp804b
Name: zinc finger protein 804B
Synonyms: LOC207618
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 207618
Homologene: 52304
Zfp941
Name: zinc finger protein 941
Synonyms: BC066028
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 407812
Rad9b
Name: RAD9 checkpoint clamp component B
Synonyms: A630082N15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231724
Homologene: 17006
Trank1
Name: tetratricopeptide repeat and ankyrin repeat containing 1
Synonyms: C030048J01Rik, A230061D21Rik, Lba1, LOC235639
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 320429
Homologene: 45845
Sclt1
Name: sodium channel and clathrin linker 1
Synonyms: Tg(CAG-sb10)1Dla, CAGGS-SB10, Tg(ACTB-sb10)1Dla, 2610207F23Rik, 4931421F20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 67161
Homologene: 27031
Auh
Name: AU RNA binding protein/enoyl-coenzyme A hydratase
Synonyms: W91705
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 11992
HGNC: HGNC:890
Homologene: 1284
Cyp2b19
Name: cytochrome P450, family 2, subfamily b, polypeptide 19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 13090
Homologene: 104114
Gpr142
Name: G protein-coupled receptor 142
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217302
Homologene: 18770
Fshr
Name: follicle stimulating hormone receptor
Synonyms: follicle-stimulating hormone receptor, FSH-R, Follitropin receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 14309
VEGA: 17
HGNC: HGNC:3969
Homologene: 117
Flg2
Name: filaggrin family member 2
Synonyms: EG229574
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229574
Homologene: 134146
Dhx30
Name: DEAH (Asp-Glu-Ala-His) box polypeptide 30
Synonyms: helG, C130058C04Rik, 2810477H02Rik, Ddx30
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 72831
Homologene: 15779
Lrrk1
Name: leucine-rich repeat kinase 1
Synonyms: C230002E15Rik, D130026O16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233328
Homologene: 23464
Dnah7b
Name: dynein, axonemal, heavy chain 7B
Synonyms: LOC227058, Dnahc7b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227058
Homologene: 41287
Them4
Name: thioesterase superfamily member 4
Synonyms: 4921507I02Rik, 2700077M13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 75778
Homologene: 14208
Olfr1026
Name: olfactory receptor 1026
Synonyms: MOR196-4, GA_x6K02T2Q125-47402610-47403533
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258577
Homologene: 73971
Agbl2
Name: ATP/GTP binding protein-like 2
Synonyms: Ccp2, Ccp2, A430081C19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 271813
Homologene: 11715
Dpep1
Name: dipeptidase 1
Synonyms: MBD
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 13479
HGNC: HGNC:3002
Homologene: 80192
Fam189a2
Name: family with sequence similarity 189, member A2
Synonyms: LOC381217
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 381217
VEGA: 19
Homologene: 3540
Zswim5
Name: zinc finger SWIM-type containing 5
Synonyms: 4933426E21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 74464
Homologene: 18958
Ace
Name: angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
Synonyms: CD143
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 11421
HGNC: HGNC:2707
Homologene: 37351
Gm5724
Name: predicted gene 5724
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 435927
Derl3
Name: Der1-like domain family, member 3
Synonyms: IZP6, 1810063P04Rik, derlin-3, 1810006I20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 70377
VEGA: 10
Homologene: 41566
R3hdm4
Name: R3H domain containing 4
Synonyms: C030046I01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 109284
VEGA: 10
Homologene: 16343
Bmp10
Name: bone morphogenetic protein 10
Synonyms: b2b2711Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12154
Homologene: 7644
Mup-ps1
Name: major urinary protein, pseudogene 1
Synonyms: Gm12547
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100417331
Gm17655
Name: predicted gene, 17655
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100504130
Gm45844
Name: predicted gene 45844
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Rpl10-ps3
Name: ribosomal protein L10, pseudogene 3
Synonyms: Gm10041
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 100043346
VEGA: 9
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 46,289,645 bp
  • C to A, chromosome 1 at 180,245,727 bp
  • G to A, chromosome 2 at 85,923,391 bp
  • A to T, chromosome 2 at 90,808,027 bp
  • A to G, chromosome 2 at 105,683,902 bp
  • T to A, chromosome 3 at 41,627,177 bp
  • T to C, chromosome 3 at 79,069,162 bp
  • A to C, chromosome 3 at 88,396,051 bp
  • T to A, chromosome 3 at 93,220,361 bp
  • A to T, chromosome 3 at 94,317,499 bp
  • C to A, chromosome 4 at 60,088,549 bp
  • A to C, chromosome 4 at 116,962,621 bp
  • T to A, chromosome 4 at 123,513,848 bp
  • T to C, chromosome 5 at 6,771,231 bp
  • T to G, chromosome 5 at 110,047,573 bp
  • A to T, chromosome 5 at 122,351,352 bp
  • A to G, chromosome 6 at 87,434,320 bp
  • A to C, chromosome 6 at 141,739,038 bp
  • T to C, chromosome 7 at 4,145,569 bp
  • C to A, chromosome 7 at 7,278,184 bp
  • A to T, chromosome 7 at 26,759,427 bp
  • T to C, chromosome 7 at 66,262,133 bp
  • A to T, chromosome 7 at 140,812,245 bp
  • A to T, chromosome 8 at 66,682,023 bp
  • A to T, chromosome 8 at 123,200,655 bp
  • A to G, chromosome 9 at 50,344,782 bp
  • A to G, chromosome 9 at 54,416,753 bp
  • A to G, chromosome 9 at 59,563,236 bp
  • C to T, chromosome 9 at 110,084,598 bp
  • A to G, chromosome 9 at 111,377,796 bp
  • A to G, chromosome 9 at 119,609,469 bp
  • A to T, chromosome 9 at 121,460,412 bp
  • G to T, chromosome 10 at 62,813,373 bp
  • T to C, chromosome 10 at 75,893,501 bp
  • A to G, chromosome 10 at 79,913,661 bp
  • A to G, chromosome 11 at 60,779,568 bp
  • A to T, chromosome 11 at 67,364,730 bp
  • T to G, chromosome 11 at 98,828,559 bp
  • A to C, chromosome 11 at 105,975,308 bp
  • A to T, chromosome 11 at 114,806,377 bp
  • T to A, chromosome 12 at 82,342,250 bp
  • A to G, chromosome 12 at 104,781,872 bp
  • A to C, chromosome 12 at 116,142,984 bp
  • T to A, chromosome 13 at 52,919,086 bp
  • T to A, chromosome 13 at 95,701,109 bp
  • T to A, chromosome 13 at 97,172,623 bp
  • T to C, chromosome 13 at 100,617,766 bp
  • A to T, chromosome 14 at 30,042,357 bp
  • T to C, chromosome 14 at 33,956,482 bp
  • C to T, chromosome 14 at 78,587,627 bp
  • T to A, chromosome 15 at 8,324,264 bp
  • C to T, chromosome 15 at 76,067,172 bp
  • C to T, chromosome 15 at 98,058,216 bp
  • C to A, chromosome 15 at 102,717,939 bp
  • A to G, chromosome 16 at 17,360,572 bp
  • A to T, chromosome 16 at 22,868,721 bp
  • T to G, chromosome 16 at 57,173,150 bp
  • T to A, chromosome 17 at 24,376,380 bp
  • T to A, chromosome 17 at 56,419,080 bp
  • A to T, chromosome 17 at 88,985,986 bp
  • A to T, chromosome 18 at 57,180,549 bp
  • A to T, chromosome 19 at 23,984,829 bp
  • A to G, chromosome 19 at 37,924,620 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6041 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044209-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.