Strain Name:
C57BL/6J-MtgxR6137Btlr
Stock Number:
044284-MU
Citation ID:
RRID:MMRRC_044284-MU
Other Names:
R6137 (G1)
Major Collection:

Gene Information

Tnpo3
Name: transportin 3
Synonyms: 5730544L10Rik, C430013M08Rik, D6Ertd313e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 320938
Homologene: 40848
Rbm47
Name: RNA binding motif protein 47
Synonyms: 9530077J19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 245945
Homologene: 36932
Chd1
Name: chromodomain helicase DNA binding protein 1
Synonyms: 4930525N21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 12648
HGNC: HGNC:1915
Homologene: 68174
Sacm1l
Name: SAC1 suppressor of actin mutations 1-like (yeast)
Synonyms: Sac1p, SAC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 83493
VEGA: 9
Homologene: 6320
Kif1b
Name: kinesin family member 1B
Synonyms: D4Mil1e, Kif1b alpha, Kif1b beta, KIF1Bp130, KIF1Bp204, N-3 kinesin, A530096N05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 16561
Homologene: 99835
Helz
Name: helicase with zinc finger domain
Synonyms: 9630002H22Rik, 9430093I07Rik, 3110078M01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 78455
Homologene: 8918
Akap13
Name: A kinase (PRKA) anchor protein 13
Synonyms: AKAP-Lbc, PROTO-LBC, PROTO-LB, Ht31, 5730522G15Rik, 1700026G02Rik, 5830460E08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 75547
HGNC: HGNC:371
Homologene: 4903
2310057M21Rik
Name: RIKEN cDNA 2310057M21 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 68277
Homologene: 11793
Ubap1
Name: ubiquitin-associated protein 1
Synonyms: 2700092A01Rik, NAG20
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 67123
Homologene: 9554
Cacnb1
Name: calcium channel, voltage-dependent, beta 1 subunit
Synonyms: Cchlb1, Cchb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 12295
HGNC: HGNC:1401
Homologene: 20186
Dars
Name: aspartyl-tRNA synthetase
Synonyms: 5730439G15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226414
HGNC: HGNC:2678
Homologene: 1032
Wwc2
Name: WW, C2 and coiled-coil domain containing 2
Synonyms: D8Ertd594e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 52357
Homologene: 32618
Dgkd
Name: diacylglycerol kinase, delta
Synonyms: DGKdelta, dgkd-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227333
HGNC: HGNC:2851
Homologene: 100054
Eef1aknmt
Name: EEF1A lysine and N-terminal methyltransferase
Synonyms: 5630401D24Rik, Mettl13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 71449
Homologene: 32285
Casp9
Name: caspase 9
Synonyms: Mch6, ICE-LAP6, Caspase-9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 12371
HGNC: HGNC:1511
Homologene: 31024
Lpl
Name: lipoprotein lipase
Synonyms: O 1-4-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 16956
HGNC: HGNC:6677
Homologene: 200
Selenot
Name: selenoprotein T
Synonyms: SelT, 5730408P04Rik, 2810407C02Rik, Selt
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 69227
Homologene: 32304
Atf7ip2
Name: activating transcription factor 7 interacting protein 2
Synonyms: 4930558K11Rik, PSM2, Get-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 75329
Homologene: 23509
Zfp236
Name: zinc finger protein 236
Synonyms: LOC240456
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 329002
Homologene: 7198
Fancm
Name: Fanconi anemia, complementation group M
Synonyms: C730036B14Rik, D12Ertd364e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 104806
VEGA: 12
Homologene: 35378
Ptgs2
Name: prostaglandin-endoperoxide synthase 2
Synonyms: Cox-2, cyclooxygenase 2, Pghs2, COX2, prostaglandin G/H synthase, PHS-2, cyclooxygenase-2, PGHS-2, Tis10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 19225
HGNC: HGNC:9605
Homologene: 31000
Cdh23
Name: cadherin 23 (otocadherin)
Synonyms: 4930542A03Rik, USH1D, mdfw, ahl, bob, nmf112, nmf181, nmf252, sals
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 22295
Homologene: 11142
Akap6
Name: A kinase (PRKA) anchor protein 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238161
VEGA: 12
HGNC: HGNC:376
Homologene: 3157
Tmem138
Name: transmembrane protein 138
Synonyms: 1700113I01Rik, 2900055D14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 72982
VEGA: 19
Homologene: 9518
Dchs1
Name: dachsous cadherin related 1
Synonyms: C130033F22Rik, 3110041P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233651
Homologene: 2771
Dnah17
Name: dynein, axonemal, heavy chain 17
Synonyms: LOC382552, 2810003K23Rik, Dnahcl1, Dnahc17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 69926
HGNC: HGNC:2946
Homologene: 72102
Fer1l6
Name: fer-1-like 6 (C. elegans)
Synonyms: EG631797
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 631797
Homologene: 53396
Myo7b
Name: myosin VIIB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 17922
HGNC: HGNC:7607
Homologene: 81947
Il17ra
Name: interleukin 17 receptor A
Synonyms: VDw217, Il17r
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 16172
HGNC: HGNC:5985
Homologene: 7378
Amigo3
Name: adhesion molecule with Ig like domain 3
Synonyms: E430002N15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 320844
Homologene: 45570
Ralgds
Name: ral guanine nucleotide dissociation stimulator
Synonyms: RalGDS, Rgds, Gnds
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 19730
HGNC: HGNC:9842
Homologene: 4562
Grin2b
Name: glutamate receptor, ionotropic, NMDA2B (epsilon 2)
Synonyms: NMDAR2B, NR2B, Nmdar2b, GluRepsilon2, GluN2B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 14812
HGNC: HGNC:4586
Homologene: 646
Grin2a
Name: glutamate receptor, ionotropic, NMDA2A (epsilon 1)
Synonyms: NR2A, NMDAR2A, GluRepsilon1, GluN2A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 14811
HGNC: HGNC:4585
Homologene: 645
Fbxw14
Name: F-box and WD-40 domain protein 14
Synonyms: Fbx12, E330009N23Rik, Fbxo12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 50757
Homologene: 110776
Topaz1
Name: testis and ovary specific PAZ domain containing 1
Synonyms: Gm9524
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 671232
VEGA: 9
Homologene: 19835
Frem3
Name: Fras1 related extracellular matrix protein 3
Synonyms: LOC333315
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 333315
Homologene: 35388
Ccdc51
Name: coiled-coil domain containing 51
Synonyms: 5730568A12Rik, Mitok
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 66658
Homologene: 11646
Pappa2
Name: pappalysin 2
Synonyms: placenta-specific 3, pregnancy-associated plasma preproprotein-A2, pregnancy-associated plasma protein-E, PAPP-A2, PLAC3, Pappe
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 23850
Homologene: 10661
Vmn2r9
Name: vomeronasal 2, receptor 9
Synonyms: EG435864
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 435864
Homologene: 129606
Nnt
Name: nicotinamide nucleotide transhydrogenase
Synonyms: 4930423F13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 18115
HGNC: HGNC:7863
1700092M07Rik
Name: RIKEN cDNA 1700092M07 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 74307
Tmc6
Name: transmembrane channel-like gene family 6
Synonyms: EVER1, D11Ertd204e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217353
Homologene: 5258
Fbxo11
Name: F-box protein 11
Synonyms: GENA 104, Jf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 225055
Homologene: 11843
Lypd3
Name: Ly6/Plaur domain containing 3
Synonyms: C4.4A, 2310061G07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 72434
Homologene: 8672
Styk1
Name: serine/threonine/tyrosine kinase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243659
Homologene: 49545
Sgsm2
Name: small G protein signaling modulator 2
Synonyms: D630003G22Rik, Rutbc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 97761
Homologene: 14780
Olfr1347
Name: olfactory receptor 1347
Synonyms: GA_x6K02T2QGBW-3218686-3217748, MOR103-11, MOR103-19_i
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258383
Homologene: 128065
Lamc2
Name: laminin, gamma 2
Synonyms: nicein, 100kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 16782
HGNC: HGNC:6493
Homologene: 4062
Nr1h3
Name: nuclear receptor subfamily 1, group H, member 3
Synonyms: LXR alpha, Unr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22259
HGNC: HGNC:7966
Homologene: 21165
Itm2c
Name: integral membrane protein 2C
Synonyms: BRI3, 3110038L02Rik, ITM3, Bricd2c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 64294
HGNC: HGNC:6175
Homologene: 11186
Immp1l
Name: IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
Synonyms: 2610528O17Rik, 1500034J20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 66541
Homologene: 41747
Olfr1040
Name: olfactory receptor 1040
Synonyms: GA_x6K02T2Q125-47615732-47614791, MOR185-12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 404323
Homologene: 79382
Tuba4a
Name: tubulin, alpha 4A
Synonyms: M[a]4, Tuba4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 22145
Homologene: 68496
Kng1
Name: kininogen 1
Synonyms: L-kininogen, H-kininigen
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 16644
HGNC: HGNC:6383
Homologene: 88343
Olfr325
Name: olfactory receptor 325
Synonyms: GA_x6K02T2NKPP-844642-843680, MOR275-5, MOR275-11_p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 258261
Homologene: 133015
Loxl4
Name: lysyl oxidase-like 4
Synonyms: 4833426I20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 67573
Homologene: 12977
Slc22a12
Name: solute carrier family 22 (organic anion/cation transporter), member 12
Synonyms: Rst, URAT1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 20521
Homologene: 56442
Prps1l3
Name: phosphoribosyl pyrophosphate synthetase 1-like 3
Synonyms: Gm5081
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 328099
Homologene: 68565
Ighv5-17
Name: immunoglobulin heavy variable 5-17
Synonyms: Gm16609
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 780794
4933402P03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to A, chromosome 1 at 75,216,055 bp
  • T to C, chromosome 1 at 85,894,692 bp
  • T to A, chromosome 1 at 87,936,381 bp
  • T to C, chromosome 1 at 128,368,439 bp
  • T to A, chromosome 1 at 150,100,993 bp
  • T to G, chromosome 1 at 153,166,153 bp
  • A to T, chromosome 1 at 158,871,543 bp
  • T to C, chromosome 1 at 162,535,886 bp
  • A to T, chromosome 2 at 28,547,588 bp
  • A to G, chromosome 2 at 86,145,969 bp
  • A to T, chromosome 2 at 91,191,851 bp
  • G to C, chromosome 2 at 105,964,208 bp
  • A to T, chromosome 3 at 58,585,284 bp
  • T to G, chromosome 4 at 41,379,262 bp
  • T to A, chromosome 4 at 141,805,349 bp
  • T to C, chromosome 4 at 149,238,426 bp
  • G to C, chromosome 5 at 66,026,283 bp
  • A to G, chromosome 5 at 108,849,016 bp
  • A to G, chromosome 6 at 29,555,268 bp
  • A to G, chromosome 6 at 120,475,582 bp
  • C to T, chromosome 6 at 131,311,016 bp
  • T to A, chromosome 6 at 135,923,458 bp
  • T to C, chromosome 7 at 6,488,845 bp
  • T to C, chromosome 7 at 24,640,494 bp
  • T to A, chromosome 7 at 75,677,416 bp
  • T to A, chromosome 7 at 105,765,106 bp
  • G to T, chromosome 7 at 131,357,613 bp
  • A to T, chromosome 8 at 47,856,263 bp
  • T to A, chromosome 8 at 68,892,747 bp
  • T to C, chromosome 8 at 80,615,047 bp
  • T to A, chromosome 9 at 108,053,728 bp
  • C to T, chromosome 9 at 109,089,415 bp
  • T to A, chromosome 9 at 109,276,222 bp
  • T to C, chromosome 9 at 122,797,756 bp
  • T to A, chromosome 9 at 123,569,005 bp
  • T to A, chromosome 10 at 60,434,512 bp
  • A to T, chromosome 11 at 58,581,068 bp
  • G to T, chromosome 11 at 69,816,696 bp
  • G to A, chromosome 11 at 74,850,851 bp
  • A to C, chromosome 11 at 98,005,782 bp
  • A to G, chromosome 11 at 107,619,060 bp
  • A to T, chromosome 11 at 117,776,328 bp
  • A to G, chromosome 11 at 118,025,654 bp
  • A to T, chromosome 12 at 53,140,354 bp
  • A to G, chromosome 12 at 57,238,888 bp
  • T to C, chromosome 12 at 65,130,382 bp
  • A to G, chromosome 12 at 113,859,295 bp
  • T to A, chromosome 13 at 119,336,328 bp
  • T to C, chromosome 15 at 58,559,206 bp
  • A to G, chromosome 16 at 9,653,449 bp
  • T to A, chromosome 16 at 10,201,411 bp
  • T to C, chromosome 16 at 23,074,645 bp
  • T to A, chromosome 17 at 15,758,688 bp
  • A to T, chromosome 17 at 88,008,669 bp
  • A to G, chromosome 18 at 31,999,974 bp
  • A to T, chromosome 18 at 82,671,794 bp
  • A to G, chromosome 19 at 6,542,724 bp
  • A to T, chromosome 19 at 8,740,784 bp
  • A to C, chromosome 19 at 10,574,835 bp
  • A to G, chromosome 19 at 42,598,793 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6137 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044284-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.