Strain Name:
C57BL/6J-MtgxR6164Btlr
Stock Number:
044310-MU
Citation ID:
RRID:MMRRC_044310-MU
Other Names:
R6164 (G1)
Major Collection:

Gene Information

Ppp2r2d
Name: protein phosphatase 2, regulatory subunit B, delta
Synonyms: 1300017E19Rik, MDS026, D7Ertd753e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 52432
Homologene: 81915
Cdk17
Name: cyclin-dependent kinase 17
Synonyms: 6430598J10Rik, Pctk2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 237459
VEGA: 10
HGNC: HGNC:8750
Homologene: 55666
Foxm1
Name: forkhead box M1
Synonyms: Mpm2, HFH-11B, Foxm1b, Trident, WIN, Fkh16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 14235
HGNC: HGNC:3818
Homologene: 7318
Iqgap1
Name: IQ motif containing GTPase activating protein 1
Synonyms: D7Ertd257e, D7Ertd237e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 29875
HGNC: HGNC:6110
Homologene: 74514
Ccdc88c
Name: coiled-coil domain containing 88C
Synonyms: Daple, 0610010D24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 68339
VEGA: 12
Homologene: 18903
Secisbp2
Name: SECIS binding protein 2
Synonyms: 2210413N07Rik, SBP2, 2810012K13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 75420
Homologene: 11415
Ppp1r9a
Name: protein phosphatase 1, regulatory subunit 9A
Synonyms: 4930518N04Rik, NRB, Neurabin I, A230094E16Rik, neurabin-I, 2810430P21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243725
Homologene: 14247
Exoc4
Name: exocyst complex component 4
Synonyms: Sec8, Sec8l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 20336
Homologene: 40654
Senp7
Name: SUMO1/sentrin specific peptidase 7
Synonyms: 6030449K19Rik, 2410152H17Rik, 2900036C23Rik, 2810413I22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 66315
Homologene: 10778
Hdac4
Name: histone deacetylase 4
Synonyms: 4932408F19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 208727
Homologene: 55946
Sgo1
Name: shugoshin 1
Synonyms: 3300001M08Rik, Sgol1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 72415
Homologene: 23642
Syne1
Name: spectrin repeat containing, nuclear envelope 1
Synonyms: enaptin165, C130039F11Rik, SYNE-1, nesprin-1, A330049M09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 64009
VEGA: 10
Homologene: 52329
Ehd4
Name: EH-domain containing 4
Synonyms: 2210022F10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 98878
HGNC: HGNC:3245
Homologene: 26430
Ap1s1
Name: adaptor protein complex AP-1, sigma 1
Synonyms: AP19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 11769
HGNC: HGNC:559
Homologene: 20342
Muc16
Name: mucin 16
Synonyms: 1110008I14Rik, LOC385009, Gm21044
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 73732
Homologene: 141193
Hspg2
Name: perlecan (heparan sulfate proteoglycan 2)
Synonyms: Pcn, per, Plc, perlecan
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 15530
HGNC: HGNC:5273
Homologene: 68473
Man2a1
Name: mannosidase 2, alpha 1
Synonyms: Mana-2, Map-2, Mana2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 17158
HGNC: HGNC:6824
Homologene: 1777
Nup160
Name: nucleoporin 160
Synonyms: 2810011M03Rik, Gtl1-13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 59015
Homologene: 32509
Anpep
Name: alanyl (membrane) aminopeptidase
Synonyms: aminopeptidase N, Apn, Cd13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 16790
HGNC: HGNC:500
Homologene: 68163
Sag
Name: S-antigen, retina and pineal gland (arrestin)
Synonyms: Arr1, arrestin 1, visual arrestin 1, rod arrestin, A930001K18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 20215
Homologene: 455
Rgs21
Name: regulator of G-protein signalling 21
Synonyms: EG624910
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 624910
Homologene: 82452
Primpol
Name: primase and polymerase (DNA-directed)
Synonyms: Ccdc111
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 408022
Homologene: 14065
Cybrd1
Name: cytochrome b reductase 1
Synonyms: Dcytb, 2210407P13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 73649
Homologene: 69387
Dnah5
Name: dynein, axonemal, heavy chain 5
Synonyms: b2b1537Clo, b2b1154Clo, Dnahc5, b2b1565Clo, b2b1134Clo, b2b3491Clo, Mdnah5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 110082
HGNC: HGNC:2950
Homologene: 1048
Pcsk5
Name: proprotein convertase subtilisin/kexin type 5
Synonyms: PC5/6A, PC6, PC5A, SPC6, b2b1549Clo, b2b585Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 18552
VEGA: 19
HGNC: HGNC:8747
Homologene: 21244
Prdm1
Name: PR domain containing 1, with ZNF domain
Synonyms: Blimp-1, b2b1765Clo, PRDI-BF1, Blimp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 12142
HGNC: HGNC:9346
Homologene: 925
Nwd1
Name: NACHT and WD repeat domain containing 1
Synonyms: A230063L24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 319555
Homologene: 72261
Rnasel
Name: ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
Synonyms: E230029I04Rik, 2-5A-dependent RNAase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 24014
Homologene: 8040
Krt34
Name: keratin 34
Synonyms: Krt1-4, 4733401E01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16672
HGNC: HGNC:6452
Homologene: 31083
Krt6a
Name: keratin 6A
Synonyms: MK6a, mK6[a], Krt2-6a, Krt2-6c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 16687
VEGA: 15
Homologene: 136794
Pik3r6
Name: phosphoinositide-3-kinase regulatory subunit 5
Synonyms: p87PIKAP, p84 Pikap
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 104709
Homologene: 46215
Muc5b
Name: mucin 5, subtype B, tracheobronchial
Synonyms: MUC9, MUC5, 2300002I04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 74180
HGNC: HGNC:7516
Homologene: 136756
Bche
Name: butyrylcholinesterase
Synonyms: C730038G20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 12038
HGNC: HGNC:983
Homologene: 20065
Wnk4
Name: WNK lysine deficient protein kinase 4
Synonyms: Prkwnk4, 2010002J11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 69847
Homologene: 13020
Ccdc148
Name: coiled-coil domain containing 148
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227933
Homologene: 16353
Myo3b
Name: myosin IIIB
Synonyms: A430065P19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 329421
Homologene: 51393
Olfr472
Name: olfactory receptor 472
Synonyms: GA_x6K02T2PBJ9-10231953-10232885, MOR204-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258770
Atp1a2
Name: ATPase, Na+/K+ transporting, alpha 2 polypeptide
Synonyms: Atpa-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 98660
HGNC: HGNC:800
Homologene: 47947
Ercc6l2
Name: excision repair cross-complementing rodent repair deficiency, complementation group 6 like 2
Synonyms: 1700019D06Rik, 0610007P08Rik, 9330134C04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 76251
Homologene: 32564
Isoc2a
Name: isochorismatase domain containing 2a
Synonyms: Isoc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 664994
Homologene: 86122
Sdk1
Name: sidekick cell adhesion molecule 1
Synonyms: 6720466O15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 330222
Homologene: 27395
Osmr
Name: oncostatin M receptor
Synonyms: OSMRB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 18414
HGNC: HGNC:8507
Homologene: 2972
Fam71e2
Name: family with sequence similarity 71, member E2
Synonyms: 4930401F20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 243822
Homologene: 89225
Fmo1
Name: flavin containing monooxygenase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 14261
HGNC: HGNC:3769
Homologene: 55520
Sh3tc1
Name: SH3 domain and tetratricopeptide repeats 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231147
Homologene: 10360
Nlrp4c
Name: NLR family, pyrin domain containing 4C
Synonyms: Nalp-alpha, Rnh2, Nalp4c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 83564
Homologene: 75315
Vmn1r66
Name: vomeronasal 1 receptor 66
Synonyms: V1re11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 171264
Cfap100
Name: cilia and flagella associated protein 100
Synonyms: C030041G11Rik, Ccdc37, C230069K22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243538
Homologene: 18456
Vmn1r23
Name: vomeronasal 1 receptor 23
Synonyms: V1rc24
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 171197
Homologene: 110825
Sele
Name: selectin, endothelial cell
Synonyms: E-selectin, CD62E, Elam
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 20339
Homologene: 389
Decr1
Name: 2,4-dienoyl CoA reductase 1, mitochondrial
Synonyms: Decr, Nadph, 1200012F07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 67460
HGNC: HGNC:2753
Homologene: 68178
Clec4a4
Name: C-type lectin domain family 4, member a4
Synonyms: Dcir2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 474145
Homologene: 133910
Prl7a1
Name: prolactin family 7, subfamily a, member 1
Synonyms: PLP-E, PLP-G, Prlpe, Prlpg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 19113
Homologene: 136279
Snrnp25
Name: small nuclear ribonucleoprotein 25 (U11/U12)
Synonyms: 3300001G02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 78372
Homologene: 11592
Cpeb4
Name: cytoplasmic polyadenylation element binding protein 4
Synonyms: 4930447D24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 67579
Homologene: 12736
Hdac1-ps
Name: histone deacetylase 1, pseudogene
Synonyms: EG15181, Gm10093
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 15181
VEGA: 17
Insyn1
Name: inhibitory synaptic factor 1
Synonyms: 6030419C18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 319477
VEGA: 9
Homologene: 18538
Olfr707
Name: olfactory receptor 707
Synonyms: GA_x6K02T2PBJ9-9276470-9275547, MOR260-8P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 194433
Homologene: 133899
Gulp1
Name: GULP, engulfment adaptor PTB domain containing 1
Synonyms: 5730529O06Rik, Ced6, CED-6, 3110030A04Rik, GULP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 70676
Homologene: 9467
Rbpjl
Name: recombination signal binding protein for immunoglobulin kappa J region-like
Synonyms: RBP-J kappa-like, RBP-L, Rbpsuhl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 19668
Homologene: 7512
Pex11a
Name: peroxisomal biogenesis factor 11 alpha
Synonyms: PEX11alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18631
HGNC: HGNC:8852
Homologene: 20829
U2af1l4
Name: U2 small nuclear RNA auxiliary factor 1-like 4
Synonyms: auxiliary factor 26, U2af26
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233073
Homologene: 134014
Mup11
Name: major urinary protein 11
Synonyms: Gm12549
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100039028
Homologene: 74304
Fam122a
Name: family with sequence similarity 122, member A
Synonyms: 2410124L17Rik, Gm9849, 2900009I07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 68034
VEGA: 19
Homologene: 75240
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to C, chromosome 1 at 44,754,351 bp
  • G to T, chromosome 1 at 87,824,453 bp
  • G to T, chromosome 1 at 92,030,154 bp
  • A to T, chromosome 1 at 144,541,297 bp
  • T to C, chromosome 1 at 153,754,392 bp
  • T to G, chromosome 1 at 162,851,410 bp
  • T to A, chromosome 1 at 164,051,817 bp
  • T to C, chromosome 1 at 172,278,892 bp
  • T to A, chromosome 2 at 58,823,633 bp
  • T to A, chromosome 2 at 70,245,410 bp
  • T to C, chromosome 2 at 71,118,274 bp
  • T to A, chromosome 2 at 90,717,876 bp
  • C to T, chromosome 2 at 120,102,208 bp
  • T to C, chromosome 2 at 164,410,879 bp
  • T to A, chromosome 3 at 73,701,056 bp
  • G to A, chromosome 4 at 15,924,347 bp
  • C to T, chromosome 4 at 60,662,240 bp
  • T to C, chromosome 4 at 137,514,655 bp
  • C to A, chromosome 5 at 35,706,246 bp
  • T to C, chromosome 5 at 137,037,386 bp
  • C to T, chromosome 5 at 142,132,069 bp
  • C to T, chromosome 6 at 5,110,715 bp
  • T to A, chromosome 6 at 33,332,283 bp
  • A to G, chromosome 6 at 57,926,055 bp
  • T to C, chromosome 6 at 90,415,786 bp
  • T to C, chromosome 6 at 122,991,874 bp
  • A to G, chromosome 6 at 128,373,935 bp
  • T to C, chromosome 7 at 4,770,678 bp
  • T to C, chromosome 7 at 4,891,489 bp
  • T to C, chromosome 7 at 6,092,508 bp
  • T to A, chromosome 7 at 10,274,402 bp
  • T to C, chromosome 7 at 30,564,582 bp
  • G to A, chromosome 7 at 79,737,379 bp
  • A to G, chromosome 7 at 79,842,205 bp
  • A to C, chromosome 7 at 80,809,106 bp
  • G to T, chromosome 7 at 106,891,928 bp
  • A to G, chromosome 7 at 107,903,388 bp
  • T to C, chromosome 7 at 138,873,013 bp
  • A to T, chromosome 7 at 141,863,345 bp
  • C to T, chromosome 8 at 46,586,442 bp
  • C to T, chromosome 8 at 72,662,186 bp
  • T to C, chromosome 9 at 18,558,379 bp
  • C to A, chromosome 9 at 58,499,247 bp
  • C to T, chromosome 10 at 5,061,429 bp
  • C to T, chromosome 10 at 44,450,195 bp
  • T to C, chromosome 10 at 93,235,469 bp
  • T to C, chromosome 11 at 31,920,584 bp
  • T to A, chromosome 11 at 32,207,647 bp
  • A to G, chromosome 11 at 68,551,973 bp
  • G to A, chromosome 11 at 100,038,446 bp
  • C to T, chromosome 11 at 101,275,068 bp
  • T to C, chromosome 12 at 100,953,383 bp
  • C to A, chromosome 13 at 27,637,643 bp
  • G to A, chromosome 13 at 51,679,860 bp
  • A to G, chromosome 13 at 63,872,344 bp
  • A to G, chromosome 15 at 6,860,352 bp
  • A to T, chromosome 15 at 28,378,343 bp
  • C to T, chromosome 15 at 101,692,573 bp
  • T to A, chromosome 16 at 56,169,754 bp
  • G to A, chromosome 17 at 53,676,953 bp
  • A to G, chromosome 17 at 64,733,724 bp
  • T to C, chromosome 17 at 78,492,287 bp
  • A to G, chromosome 19 at 17,836,953 bp
  • T to A, chromosome 19 at 24,477,086 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6164 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044310-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.